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All Journal International Journal of Electrical and Computer Engineering Majalah Ilmiah Teknologi Elektro TELKOMNIKA (Telecommunication Computing Electronics and Control) Physics Student Journal Jurnal EECCIS Journal of Natural A Natural B The Journal of Pure and Applied Chemistry Research Jurnal Fisika Unand ELKOMIKA: Jurnal Teknik Energi Elektrik, Teknik Telekomunikasi, & Teknik Elektronika Science and Technology Indonesia al Kimiya : Jurnal Ilmu Kimia dan Terapan Majalah Ilmiah Teknologi Elektro
Setyawan Purnomo Sakti
Department Of Physics, Brawijaya University, Malang
Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Control & Systems Engineering Earth & Planetary Sciences Electrical & Electronics Engineering Energy Engineering Environmental Science Materials Science & Nanotechnology Medicine & Pharmacology Physics

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Journal : International Journal of Electrical and Computer Engineering

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Long term temperature stability of thermal cycler developed using low profile microprocessor cooler Setyawan Purnomo Sakti; Adin Okta Triqadafi; Aldi Dwi Putra; Triswantoro Putro; Dewi Anggraeni
International Journal of Electrical and Computer Engineering (IJECE) Vol 13, No 1: February 2023
Publisher : Institute of Advanced Engineering and Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11591/ijece.v13i1.pp278-287

Abstract

Developing a low-cost thermal cycler for a polymerase chain reaction (PCR) is becoming interested in the pandemic era caused by viruses. PCR is the standard gold for the diagnostic. However, in a low-income country, the availability of the device is limited. In this work, the development of a thermal cycler uses electronic modules available in the market. The central part is thermoelectric for heating and cooling, an embedded system to control, and a low-profile cooling fan. The system temperature control used a combination of feedforward, bang-bang, and proportional-integral-derivative (PID) control. The control parameter of the PID was successfully obtained by using Chien servo tuning. The feedforward and bang-bang control are used to optimize the cooling cycle and minimize the rise time. The system shows a well-suited temperature accuracy at the denaturation, annealing, and extension temperature with a temperature deviation of less than 0.5 °C. System performance is maintained even though the system has been running non-stop for 24 hours. The low-profile cooling fan, which is usually used for CPU cooling, shows good results in maintaining temperature stability.
Co-Authors Achmad Nurul Fauzie Adin Okta Triqadafi Agus Naba Akhmad Sabarudin Akhmad Sabarudin Aldi Dwi Putra Aprilia Nur Tasfiyati Arinto Yudi Ponco Wardoyo Dewi Anggraeni Didik Rahadi Santosa Didik Rahadi Santoso Eko Malis Elvina Dhiaul Iftitah Farida Wahyuni Fenny Irawati Hari Arief Dharmawan Hariyadi Soetedjo Lalu Sahrul Hudha Layli Amaliya Masruroh Masruroh Masruroh MASRUROH MUHAMMAD ULIN NUHA Nalle, Ferry Chrismiadi Nur Chabibah Rahmadwati Rizal Y Aji Saputra, Aditya Ilham Sigit Kurniawan Sri Sugiarti Sukma Wahyu Fitriani, Sukma Wahyu Triswantoro Putro Umi Salamah Unggul P. Juswono Unggul Punjung Juswono