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All Journal Majalah Kedokteran Andalas Human Care Journal Warta Pengabdian Andalas: Jurnal Ilmiah Pengembangan Dan Penerapan Ipteks Jurnal Ilmu Kesehatan Indonesia (JIKSI) Vitalitas Medis : Jurnal Kesehatan Dan Kedokteran Multidisciplinary Indonesian Center Journal
Nita Afriani
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Religion Humanities Computer Science & IT Earth & Planetary Sciences Education Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Ekspresi HER2/neu(c-ErbB2) pada Kanker Kolorektal Nita Afriani; Ening Krisnuhoni; Nur Rahadiani
Majalah Kedokteran Andalas Vol 37 (2014): Supplement 2 | Published in December 2014
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (4684.439 KB)

Abstract

Kanker kolorektal merupakan keganasan pada kolon dan rektum, penyebab morbiditas danmortalitas ketiga terbanyak diantara keganasan lainnya. Penelitian ekspresi HER2 pada kankerkolorektal memiliki rentang yang cukup jauh yaitu 0-83% dan belum pernah dipublikasi dilndonesia. Penelitian ini bertujuan untuk menilai ekspresi HER2 pada kanker kolorektal. Studicross-secfiona/ dilakukan terhadap 51 sediaan blok parafin kanker kolorektal rentang tahunJanuari 2011-Desember 2012 di Departemen Patologi Anatorni RS Cipto MangunkusumoJakarta. Penilaian karakteristik sampel diambil dari rekam medis dan penilaian histopatologidari sediaan HE pasien kanker kolorektal. Pulasan imunohistokimia HER2 menggunakanantibodipoliklonalantiHER2(DAKO). Rata-rata usia penderita adalah 57.8t13.54tahun,58.8%penderita adalah laki-laki dan 41.2o/o perempuan. Semua sediaan adalah adenokarsinomakolorektal. Ekspresi HER2 positif ditemukan sebanyak 5(9.8%) kasus.AbstractColorectal cancer is a neoplasia of colon and rectum ,and also the 3rd leading cause ofmorbidity and mortality among men and women in the world. HER2 expression has controversialresults ranging from 0-83% and never been pubiished in lndonesia. This research aims tostudy HER2 expression in colorectal cancer. Cross-sectional study was conducted in 51 casesof colorectal cancer from January 2011 until December 2012 in Pathology Department ofCipto Mangunkusumo Hospital. Patient characteristic was reviewed from medical record andhistopathologic was evaluated from HE slides. lmunohistochemistry staining used anti HER2polyclonal antibody frorn DAKO. Mean age was 57.8113.54 years, 58.8% were males and41.2o4 were females. Positive HER2 was 5 cases (9.8%).
KORELASI KECEMASAN DENGAN JENIS TENSION TYPE HEADACHE PADA MAHASISWA KEDOKTERAN ANGKATAN 2019 DI UNIVERSITAS ANDALAS Dian Pertiwi Alty; Restu Susanti; Nita Afriani
HUMAN CARE JOURNAL Vol 5, No 3 (2020): Human Care Journal
Publisher : Universitas Fort De Kock

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32883/hcj.v5i3.766

Abstract

Tension type headache is the most common primary headache. Tension type headache can be triggered by anxiety. Anxiety often occurs in medical students, especially in new students. The aim of this  study was to determine the correlation between anxiety and tension-type headache among medical students batch 2019 in Andalas University. This was an analytic study using cross-sectional design. Sampling was done by stratified random sampling technique and we obtained sample from 79 respondents. Headache diagnosis was based on the consensus of PERDOSSI 2018 which in accordance with International Classification of Headache Disorder 3rd Edition (Beta version). Anxiety was diagnosed by using Hamilton Rating Scale for Anxiety questionnaire that had been validated. The correlation between variabels was analyzed using Spearman Rho test. The results of univariate analysis showed that the majority of respondent were women (69,6%). The most common anxiety category was mild anxiety (57%). The most common tension-type headache type was infrequent type (62%). The results of bivariate analysis showed 8 sample (34,8%) which experienced moderate-severe anxiety had infrequent tension-type  headache and 41 samples (73,2 %) which experienced mild anxiety also had infrequent tension type headache. This study showed that anxiety was positively correlated with tension-type headache (r=0,327 p=0.003)
Promosi Kesehatan Periksa Payudara Sendiri (SADARI) pada Ibu-Ibu Majelis Taklim Mesjid Baitul Chair Komplek Bea Cukai Teluk Bayur Kota Padang Nita Afriani; Biomechy Oktomalio Putri; Malinda Meinapuri; Sheila Diana; SM Rezvi; Eryati Darwin; Roza Silvia; YN Zuhal Chaisart Chaniago; Tegar Abdillah
Warta Pengabdian Andalas Vol 30 No 2 (2023)
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat (LPPM) Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jwa.30.2.297-303.2023

Abstract

Breast self-examination (BSE) is a breast examination carried out by the woman herself every month regularly. BSE as a step for early detection of breast cancer is highly recommended for women, especially those aged 40 years and over, because the higher the age, the greater the risk of developing breast cancer. This activity aimed to determine the level of knowledge and attitudes and carry out health promotion about BSE to the pilgrim women of the Baitul Chair Mosque, Teluk Bayur, Padang. 11 women of the society attended this activity. The level of knowledge and attitudes regarding BSE was assessed using a simple questionnaire consisting of five questions regarding knowledge and attitudes, respectively. The survey resulted in no history of breast cancer or family history of breast cancer; as many as 81.8% of mothers had never received information about BSE before. The level of knowledge showed that 63.6% of mothers have good knowledge and a good attitude about BSE, 55.5%. Health behaviour, knowledge and attitudes must be improved, including health promotion. Health promotion as one of the driving factors can increase the knowledge and attitudes that will manifest in BSE actions for early detection of breast cancer.
Gambaran Kadar Trigliserida dan Tekanan Darah pada Masyarakat Perumahan Universitas Andalas Caesar Rayhand Arrafif Nasution; Eti Yerizel; Nita Afriani
Vitalitas Medis : Jurnal Kesehatan dan Kedokteran Vol. 2 No. 2 (2025): Vitalitas Medis : Jurnal Kesehatan dan Kedokteran
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62383/vimed.v2i2.1453

Abstract

Hypertension is a disease that often causes death and complications related to cardiovascular disease. The prevalence of hypertension in Indonesia is 34.11%. One of the factors that influence the incidence of hypertension is high levels of the triglycerides in the blood (hypertriglycerida). This study aims to determine the description between triglycerides levels and the incidence of hypertension in the community of Bandar Buat Village. This research was a descriptive study with 29 respondents taken using total sampling techniques from secondary data of community service in the village of Bandar Buat in 2019. Data were selected based on inclusion criteria and exclusion criteria, the data were processed in table to generate frequency and percentages distribution. The results showed that the majority of respondents aged 18-50 years (55.1%), were women (58.6%). The results showed that respondents' triglycerides levels were dominated by hypertriglycerida (58.6%) and blood pressure classification was dominated by normotension (55.2%). Based on age, most people with hypertriglycerida and hypertension are above 50 years old. Based on sex, hypertriglycerida and hypertension both are sufferers more frequent in men. The number of percentage were 66.7%; 75% respectively. The conclusion of this research is the triglycerides level of respondents is dominated by respondents with hypertriglycerida, the majority are aged>50 years, male sex. The incidence of hypertension is high, with majority sufferers aged>50 years, male sex.
CREATIVE PROBLEM SOLVING LEARNING MODEL USING QUIZIZZ APPLICATION ON STUDENTS' LEARNING OUTCOMES IN INDONESIAN LANGUAGE SUBJECTS IN GRADE VIII OF SMP NEGERI 1 CINA, BONE REGENCY Nita Afriani; Jusman; Suhardiman
Multidisciplinary Indonesian Center Journal (MICJO) Vol. 2 No. 2 (2025): Vol. 2 No. 2 Edisi April 2025
Publisher : PT. Jurnal Center Indonesia Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62567/micjo.v2i2.586

Abstract

The use of technology in education is an alternative to improve the quality and quantity of results and processes, including sources in learning where teachers and students are required to actively use technology in the teaching and learning process. This research is a quantitative research with a quasi-experimental method . The purpose of this study was to determine the effect of the use of creative problem solving learning media based on technology using the Quizizz application on student learning outcomes in the Indonesian language subject of class VIII SMP Negeri 1 Cina, Bone Regency. The research was conducted in March-May 2024. The research location was at SMP Negeri 1 Cina, Bone Regency. Respondents were 35 students consisting of 19 male respondents and 16 female respondents. Data analysis techniques used the help of excel and spss applications. The results of the study showed that there was an effect of the use of creative problem solving learning media based on technology using the Quizizz application on student learning outcomes p value <0.05. the conclusion of this study is that there is an effect of the use of creative problem solving learning media based on technology using the Quizizz application on student learning outcomes.
Pengaruh Pemberian Human Wharton’s jelly mesenchymal stem cells Terhadap Gambaran Histopatologi Sel Hepatosit yang Diinduksi Aluminium Klorida Putri Amran, Fajriana Anggun; Nita Afriani; Dolly Irfandy; Eryati Darwin; Eka Nofita; Tofrizal
Jurnal Ilmu Kesehatan Indonesia Vol. 6 No. 3 (2025): September 2025
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jikesi.v6i3.1508

Abstract

Latar Belakang:   Aluminium klorida (AlCl3) adalah zat hepatotoksik yang dapat ditemukan dalam air, udara, serta berbagai bahan makanan , sehingga manusia berpotensi terpapar setiap hari. Paparan kronis AlCl3 diketahui menimbulkan akumulasi pada hepar yang berujung pada kerusakan hepatosit. Gambaran histopatologi khas akibat paparan toksik ini meliputi degenerasi hidrofik, piknosis, karioreksis, kariolisis, dan nekrosis.  Dengan. Human Wharton’s jelly mesenchymal stem cells (HWJ-MSCs), yang berasal dari jaringan mucoid plasenta, memiliki sifat multipotent, regenerative dan imunomodulator, sehingga berpotensi memperbaiki kerusakan hepatosit. Objektif:    Penelitian ini bertujuan unutuk mengetahui pengaruh pemberian HWJ-MSCs terhadap gambaran histopatologi sel hepatosit tikus yang diinduksi aluminium klorida Metode:    Penelitian eksperimental laboratorik dengan desain Post Test Only Control Group dilakukan pada 18 ekor tikus wistar jantan. Hewan dibagi menjadi tiga kelompok : kontrol negative, kontrol positif dengan induksi AlCl3 dan perlakuan dengan induksi AlCl3 ditambah pemberian HWJ-MSCs. Hepar difiksasi, diproses histologis, dan diwarnai menggunakan H&E. Presentase kerusakan hepatosit dinilai pada tiga lapangan pandang dengan pembesaran 400x Hasil:      Rerata kerusakan hepatosit adalah 1,7% pada kontrol negative, 68,7% pada kontrol positif, dan 35,8% pada kelompok perlakukan. Tampak perbaikan gambaran histopatologi pada kelompok perlakuan dibanding kelompok kontrol kontrol positif. Kesimpulan:  Pemberian HWJ-MSCs berpotensi menurunkan kerusakan hepatosit akibat induksi AlCl3 meskipun dosis yang diberikan belum cukup untuk mengembalikan kondisi sel hepatosit normal.
Co-Authors Caesar Rayhand Arrafif Nasution Dian Pertiwi Alty Ening Krisnuhoni Eryati Darwin Eti Yerizel Jusman Malinda Meinapuri Nur Rahadiani Putri Amran, Fajriana Anggun Putri, Biomechy Oktomalio Restu Susanti Roza Silvia Sheila Diana SM Rezvi Suhardiman Tegar Abdillah Tofrizal YN Zuhal Chaisart Chaniago