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All Journal JCPS (Journal of Current Pharmaceutical Sciences) Jurnal Kesehatan Tambusai Jurnal Pengabdian kepada Masyarakat Journal of Innovation Research and Knowledge Jurnal Pengabdian Masyarakat Bangsa E-Amal: Jurnal Pengabdian Kepada Masyarakat Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan Journal of Medicine and Health
Rizka Mulya Miranti
Universitas Muhammadiyah Banjarmasin
Agriculture, Biological Sciences & Forestry Arts Humanities Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Dentistry Economics, Econometrics & Finance Education Energy Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Mathematics Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

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Journal : Journal of Innovation Research and Knowledge

 1 
EFEKTIVITAS INFUSA JAHE MERAH (ZINGIBER OFFICINALE VAR. RUBRUM) SEBAGAI ANTIDIARE PADA MENCIT PUTIH JANTAN YANG DI INDUKSI OLEUM RICINI DENGAN METODE TRANSIT INTESTINAL Yulis Azizah; Rizka Mulya Miranti; Dedi Hartanto; Retna Eka Dewi
Journal of Innovation Research and Knowledge Vol. 3 No. 3: Agustus 2023
Publisher : Bajang Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53625/jirk.v3i3.6348

Abstract

Red ginger is a plant of the Zingiberaceae family which contains active compounds which are consider to have a major contribution to the anti-diarrheal effect are steroids, tannins, flavonoids, and saponins. The purpose of this study was to determine if red ginger infusion has an antidiarrheal effect and what is the effective dose if it has an anti- diarrheal effect. This research is an experimental with a Completely Randomised plan (CRP) with a one way model. Twenty-four mice were randomly assigned to 6 groups of 4 mice within each group. The Red ginger infusion was tested with 3 different dosage variations; 1.047 g/kgBW, 2.095 g/kgBW, and 4.19 g/kgBW. The Antidiarrheal activity in this study was determined by computing the ratio of the bowel length passed through the marker to total length of the intestine. The results showed that red ginger infusion has an anti-diarrheal effect. Infusion of red ginger at doses of 1.047 g/kg BB, 2.095 g/kg BB and 4.19 g/kgBW, resulting in average ratios of 0.596, 0.37975 and 0.164125, consecutively. Based on a statiscal data analysis with the Mann Whitney Test, it was obtained that the ratio between a dose of 4.19 g / kgBW and the Loperamide comparison group of 4 mg / kgBW dose did not have a meaningful difference. So the most effective dose of red ginger infusion as an anti-diarrhea is 4.19 g/kgBW.
UJI AKTIVITAS ANTIOKSIDAN PADA EKSTRAK ETANOL 70% TANAMAN TERATAI PUTIH (Nymphaea nouchali L) Yulianita Pratiwi Indah Lestari; Raudatul Patimah; Mustika Muthaharah; Rizka Mulya Miranti; Tuty Mulyani; Aris Purwanto
Journal of Innovation Research and Knowledge Vol. 3 No. 4: September 2023
Publisher : Bajang Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53625/jirk.v3i4.6551

Abstract

Many aquatic plants grow in these rivers, one of which is the lotus. Lotus (Nymphaea) is a plant that often lives in the swamplands of South Kalimantan, especially Banjarmasin. The lotus is a wild plant in its natural habitat, which is not foreign to Indonesian people. Some Indonesian people only know about the beauty of this plant. It turns out that apart from its beauty, the lotus also has benefits for curing various diseases. The lotus plant can also be used as medicine because it contains several different chemical ingredients in each part. This research aims to determine the antioxidant activity of extracts from various parts of the White Lotus plant (Nymphaea nouchali L) using the DPPH method. The plant parts tested include: flower parts, flower stalks, leaves and petioles. Based on the research results, the highest antioxidant activity test was found in flower extract, namely with an IC50 value of 66.906 μg/mL, and the lowest was found in leaf extract, namely with an IC50 value of 99.449 μg/mL. Quercetin as a comparison standard has an IC50 value of 6.337 μg/mL with a "very strong" antioxidant activity category, while flower extract, flower stalk extract, leaf extract and leaf stalk extract have a "strong" antioxidant activity category.
UJI ANTIINFLAMASI EKSTRAK ETANOL BIJI PETAI (PARKIA SPECIOSA HASSK.) TERHADAP MENCIT PUTIH (MUS MUSCULUS) JANTAN YANG DIINDUKSI KARAGENIN Latipah Latipah; Rizka Mulya Miranti; Tuty Mulyani
Journal of Innovation Research and Knowledge Vol. 3 No. 9: Februari 2024
Publisher : Bajang Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Petai seeds contain phenolic compounds, flavonoids, terpenoids, and steroids which are thought to have a role in anti-inflammatory effect. In this study, the anti-inflammatory effect of petai seed extract was tested using the paw edema method induced by 1% carrageenin. The test was carried out by dividing 5 groups, namely negative control, positive control and ethanol extract of petai seeds with doses of 100,200 and 300 mg/kgBW. In this study, there were 4 test parameters, namely the percent edema, AUC (Area Under Curve), the percent inhibition of inflammation, and the percent relative potential of anti-inflammatory power. The test data were analyzed by analysis of variance (ANOVA) then followed by the Post Hoc test using the LSD (Least Square Differences) method with a 95% confidence level to see the differences between treatments. Based on the results of these tests, the results stated that the administration of ethanol extract of petai seeds had anti-inflammatory power with the best dose of 300 mg/kgBB.
Co-Authors Andreanus A. Soemardji Aris Purwanto Aris Purwanto Dewi, Retna Eka Eliza Ardika Fajeriyati, Nurul Fandiny, Yeny fatimah Fatimah Halisa, Siti N Hartanto, Dedi Hasan Ismail Jihan Jihan Jihan Jihan, Jihan Latipah Latipah Maharani, Dewi Mi'rajunnisa Mi’rajunnisa, Mi’rajunnisa Muhammad Muhammad Mulyani, Risya Mulyani, Tuty Mustharah, Mustika Mustika Muthaharah Nashihah, Siti Norhikmah Norhikmah Nurma, Nurma Nurul Fajeriyati Rabiatul Adewiyah Rahmawati, Rahmawati Raudatul Patimah Raudatul Patimah Raudatul Patimah, Raudatul Rizka Amalia Safitri, Salsabila Nurlaila Salsabila, Nur Syifa Salsabilla, Syifa Aulia Sari, Cindy Fransiska Sazidan, Akhbar Arya Jouraist Siti Kusmardiyani Tuty Mulyani Tuty Tuty Mulyani Yulianita Pratiwi Indah Lestari Yulis Azizah Yuspa, Yuspa