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All Journal Indonesian Journal of Urology Emerging Science Journal Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia Jurnal Aisyah : Jurnal Ilmu Kesehatan Jurnal Ilmu Bedah Indonesia JOURNAL LA MEDIHEALTICO Narra J Open Access Indonesian Journal of Medical Reviews Journal of Medical Science; Jurnal Ilmu Medis Rumah Sakit Umum Daerah dr. Zainoel Abidin, Banda Aceh International Journal of Public Health Excellence (IJPHE) Zona Kedokteran: Program Studi Pendidikan Dokter Universitas Batam Eduvest - Journal of Universal Studies Jurnal Kedokteran Hewan Journal of International Surgery and Clinical Medicine
Ismy, Jufriady
Department Of Surgery, Zainoel Abidin Hospital, Faculty Of Medicine, Universitas Syiah Kuala
Aerospace Engineering Biochemistry, Genetics & Molecular Biology Computer Science & IT Dentistry Education Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary

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Severe foreskin adhesion and meatal stenosis – complications after Circumcision: A Case Report Khalilullah, Said Alfin; Ismy, Jufriady
Journal of International Surgery and Clinical Medicine Vol. 3 No. 1 (2023): (Available online: June 2023)
Publisher : Surgical Residency Program Syiah Kuala University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/jiscm.v3i1.32

Abstract

Introduction: Although circumcision is the most common surgical surgery performed on newborn males, problems can still occur regardless of the technique utilized by the operator. Case description: This case report aims to highlight the case of a 13-year-old boy who presented with severe foreskin adhesion and meatal stenosis after circumcision and underwent surgical reconstruction. During surgery, the foreskin firmly bonds to the glans and cannot be scraped away. Even the glans penis is injured when released abruptly. The glans penis was then clearly visible and could be distinguished between the skin and glans penis after a circumferential incision was performed on the penis skin above the coronary sulcus. Adhesiolysis was then conducted from the proximal to the distal wound. After that, the meatoplasty was performed. Conclusion: Since issues related to complications of circumcision continue to emerge, it is important to have a proper understanding of the circumcision procedure and how to manage the complication. To our knowledge, this is the new insight into managing severe foreskin adhesion with a good outcome.
A potential treatment for erectile dysfunction: Effect of platelet-rich plasma administration on axon and collagen regeneration in cavernous nerve injury Ismy, Jufriady; Khalilullah, Said A.; Maulana, Reza; Hidayatullah, Furqan
Narra J Vol. 4 No. 2 (2024): August 2024
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v4i2.880

Abstract

Recent studies highlighted the role of platelet-rich plasma (PRP) in progenitor cell homing, migration, and nerve cell regeneration while also inhibiting fibrosis and apoptosis in cavernous nerve injury (CNI). The aim of this study was to investigate the effect of PRP administration on axon and collagen regeneration in CNI. A true experimental study using a post-test-only control group design was conducted. Twenty-five male Wistar rats (Rattus norvegicus), weighing 200–300 grams, were divided into five groups: two control groups (sham procedure and negative control), and three experimental groups receiving local PRP, intraperitoneal PRP, and a combination of local and intraperitoneal PRP. The cavernous nerve was injured with a hemostasis clamp for one minute before 200 µL of 200 PRP was injected locally, intraperitoneally, or both, depending on the group. After four weeks, the rats were euthanized, tissue segments (2 mm) from each cavernous nerve and mid-penis were collected and analyzed for collagen density, axon diameter, and number of myelinated axons. Our study found that collagen growth was slower in CNI group without PRP (sham procedure) compared to all PRP groups (local, intraperitoneal, and combination). The intraperitoneal PRP group had the highest collagen density at 5.62 µm; however, no significant difference was observed in collagen density among all groups (p=0.056). Similar axon diameter was found across the groups, with no statistically significant difference observed (p=0.856). In the number of myelinated axons, a significant difference was found among all groups with significantly more axons in local PRP and combined local and intraperitoneal PRP groups compared to others (p=0.026). In conclusion, PRP administration improved a number of myelinated axons in CNI, suggesting PRP role in CNI regeneration and the potential for an innovative approach to treating erectile dysfunction associated with CNI.
The Diagnosis and Management of Bladder Cancer: A Literature Review Ikhwan, Haznur; Dahril; Ismy, Jufriady; Ridha, Muhammad; Mauny, Muhammad Puteh; Khalilullah, Said Alfin; Triyaka, Rendy; Maulana, Reza; Hidayatullah, Furqan
International Journal of Public Health Excellence (IJPHE) Vol. 4 No. 1 (2024): June-December
Publisher : PT Inovasi Pratama Internasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55299/ijphe.v4i1.1061

Abstract

Cancer is still one of the health problems around the world. Cancer is an uncontrolled (abnormal) cell division and can invade surrounding tissues and can also spread to other parts of the body through the blood and lymphatic system known as metastasis. This disease is often diagnosed in men aged 50-80 years with an average age of 73 years. Bladder cancer is divided into transitional cell carcinoma (95%), squamous cell carcinoma (3%), adenocarcinoma (2%), and less than 1% small cell tumors (paraneoplastic syndrome). Risk factors for this disease are smoking, exposure to carcinogenic substances, drugs, infection with the parasite Schistosoma haematobium, chronic irritation (stone disease), physical trauma (in the uroepithelial layer), infectious diseases and those that have not been proven to be the cause are coffee, alcohol, saccharin and cyclamate sweeteners. The prognosis of the disease depends on histologic examination to see the stage of the disease and by tissue biopsy. Methods: This paper is based on a literature search of clinical practice guidelines, scientific literature, websites, and textbooks on the topic of bladder cancer. Results and Discussion: Hematuria is the main clinical symptom in addition to other symptoms as a complaint of bladder cancer. The disease is divided into non-muscle-invasive bladder cancer (NMIBC) and muscle-invasive bladder cancer (MIBC). Non-invasive and invasive cancer conditions play an important role in the treatment and prognosis of the disease. MIBC is a disease condition with high morbidity and mortality. Conclusion: Cystoscopy followed by biopsy resection is the diagnostic standard followed by anatomic pathology examination (histology and cytology) for definitive diagnosis of the disease. The prognosis will be better if the disease is still at superficial and non-invasive stage (Ta), so that only transurethral tumor resection followed by chemotherapy drugs, intravesical and results will be more satisfactory.
Evaluasi Uji Diagnostik POSSUM Dan P-POSSUM Sebagai Prediktor Mortalitas Pada Pasien Laparotomi Emergensi Di Rumah Sakit Umum Daerah Dr. Zainoel Abidin Banda Aceh Putra, Novrianda Eka; Muslim, Muslim; Ismy, Jufriady; Erdani, Ferry; Hidayat, Imam
Majalah Kedokteran Indonesia Vol 75 No 1 (2025): Journal of The Indonesian Medical Association - Majalah Kedokteran Indonesia, Vo
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.75.1-2025-1605

Abstract

Introduction: Laparotomy is a frequent surgical procedure carried out in emergency settings due to various indications and related to a considerable amount of postoperative mortality rate. POSSUM and P-POSSUM are known as two of the most favorable methods to calculate the likelihood of postoperative mortality, so that optimization of patient management can be achieved. The purpose of this research is to assess the predictive power of POSSUM and P-POSSUM scoring systems for emergency laparotomy patients in terms of accuracy, sensitivity, specificity, and Area Under the Curve (AUC) value. Method: This study uses an observational analytical method with a prospective cohort approach, and was performed at Dr. Zainoel Abidin Regional General Hospital Banda Aceh since January until May 2024. Mortality status was observed for 30 days after surgery. The accuracy of POSSUM and P-POSSUM was assessed based on sensitivity, specificity, and AUC values obtained from the Receiver Operating Characteristic (ROC) curve. Results: A total of 13 subjects experienced mortality within 30 days after surgery out of 29 subjects involved in this study. Analysis based on the ROC curve shows that POSSUM and P-POSSUM equally have 100% sensitivity and 75% specificity. The AUC values obtained were 0.851 and 0.837 respectively. Conclusion: POSSUM and P-POSSUM scoring systems have good accuracy as mortality predictors in emergency laparotomy patients.
Pengaruh Pemberian Ketoprofen Supposituria terhadap Penurunan Intensitas Nyeri saat Pelepasan Kateter Uretra Menetap Jufriady Ismy; Andreas; Yudhi Aulia
Journal of Medical Science Vol 3 No 1 (2022): Journal of Medical Science
Publisher : LITBANG RSUDZA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (296.37 KB) | DOI: 10.55572/jms.v3i1.54

Abstract

Kateter urin adalah selang yang dimasukkan ke dalam kandung kemih untuk mengalirkan urine. Kateter ini biasanya dimasukkan melalui uretra ke dalam kandung kemih. Pemberian ketoprofen digunakan untuk mengurangi intensitas nyeri pada saat pelepasan kateter. Tujuan dari penelitian ini adalah untuk mengetahui efektivitas pemberian Ketoprofen pada pasien saat pelepasan kateter urin. Tujuan jangka panjang dari penelitian ini adalah mendapatkan suatu metode intervensi pendukung manajemen nyeri yang dapat dilakukan oleh perawat di ruang rawat bedah sehingga dapat meningkatkan kepuasan pasien terhadap pelayanan yang diberikan. Penelitian ini merupakan penelitian uji klinis (clinical trials) desain paralel. Uji klinis adalah penelitian eksperimental terencana yang dilakukan pada manusia. Peneliti pada penelitian uji klinis akan memberikan perlakuan atau intervensi pada 60 peserta atau subjek penelitian. Terdapat 2 kelompok penelitian yang akan dinilai. Terdapat 30 sampel akan diberikan perlakuan ketoprofen supposituria, dan 30 sampel sebagai kelompok kontrol. Pengambilan sampel menggunakan teknik consecutive sampling dengan kriteria inklusi: 1) Pasien diruang rawat bedah dan memakai kateter; 2) masa pemasangan kateter tidak lebih dari 3 hari; 3) pasien diatas 18 tahun; 4) pasien tidak menjalani operasi pada uretra vesica urinaria. Hasil penelitian menggunakan normalitas data menggunakan uji kolmogorov-smirnov menunjukkan bahwa nilai p-value < 0.05 pada masing-masing kelompok, maka dapat disimpulkan bahwa data berdistribusi tidak normal. Dari analisis uji Mann Whitney ditemukan pengaruh yang signifikan pada pemberian ketoprofen terhadap penurunan skala nyeri (p <0.05). Kami akan mensosialisasikan kepada devisi Bagian Urologi/ KSM Ilmu Bedah RSUDZA/FKUSK untuk menjadikan hasil penelitian ini menjadi standar operasional prosedur (SOP) yang harus di jalankan pada pasien-pasien yang dilakukan pelepasan kateter.
Pengaruh Diuretik Terhadap Stone-Free Rate Batu Ureter dengan Pneumatic Lithotripsy Jufriady Ismy; Muhammad Ridha; Dahril; Rayyan Al Faruqi; Muyasir
Journal of Medical Science Vol 3 No 2 (2022): Journal of Medical Science
Publisher : LITBANG RSUDZA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55572/jms.v3i2.82

Abstract

Pneumatic Lithotripsy (PL) is considered effective in fragmenting hard stones, and this procedure can also be performed transurethrally and percutaneously on large stones. This study aimed to see the percentage of Stone Free Rate (SFR) by administering force diuretics to ureteral stones that were crushed using PL. Previous studies have found that intravenous loop diuretic administration is effective, safe, and efficient in obtaining a much higher percentage of SFR and can reduce the average number of sessions per stone during extracorporeal shock wave lithotripsy (ESWL). We identified study subjects from early July-September 2022 and obtained as many as 38 study subjects (SP) with stones in the distal ureter <20mm. Subjects were randomly selected and divided into two groups: the group given diuretics (K2) and not given (K1). With a 90% confidence degree and 15% sampling error, based on Lameshow's formula, 30 SP can be observed; eight other subjects were excluded because they experienced a decrease in systolic pressure >25% (5 SP) and the remaining stones came out without splitting (3SP). The results obtained were SFR levels that were statistically significant (p<0.05) and clinically using the Mann-Whitney statistical test. Administration of diuretics to patients with distal ureteral stones undergoing URS with Pneumatic Lithotripsy is safe and effective as an anti-retropulsion method. It is the strategy of choice in centers that do not provide laser lithotripsy or flexible ureteroscope.
Optimizing quality of life for prostate cancer patients: a comprehensive approach Juliar Adista, Rangga; Ismy, Jufriady
Eduvest - Journal of Universal Studies Vol. 5 No. 2 (2025): Eduvest - Journal of Universal Studies
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/eduvest.v5i2.33281

Abstract

This comprehensive review examines evidence-based interventions for optimizing quality of life in prostate cancer patients. Synthesizing a multifaceted approach, the review encompasses lifestyle modifications, educational support, cognitive-behavioural therapies, and survivorship care coordination. Robust evidence underscores the efficacy of integrating tailored exercise regimens, dietary modifications, and multidisciplinary care teams to address the multifaceted physical and psychological impacts of prostate cancer. Cognitive-behavioural approaches demonstrate significant value in mitigating emotional distress, while survivorship care coordination, interfacing with primary care, emerges as crucial for ensuring seamless transitions and long-term health optimization. Acknowledging inherent limitations, the review delineates key research recommendations to inform future investigations, emphasizing the dynamic nature of healthcare advancements in the ongoing pursuit of superior patient outcomes.
FAKTOR - FAKTOR YANG MEMPENGARUHI TINGKAT KELANGSUNGAN HIDUP 5 TAHUN PASIEN DENGAN KANKER KANDUNG KEMIH DI RSUD DR. ZAINOEL ABIDIN BANDA ACEH Merysia Karmila; Jufriady Ismy; Imam Hidayat; Safrizal Rahman; Muhammad Ridha; Muhammad Azmi Fanany
Zona Kedokteran: Program Studi Pendidikan Dokter Universitas Batam Vol 15 No 2 (2025): Zona Kedokteran: Program Studi Pendidikan Dokter Universitas Batam
Publisher : Universitas Batam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37776/zked.v15i2.1725

Abstract

ABSTRACT Background: Bladder cancer is the tenth most common cancer worldwide, and its prevalence is gradually increasing globally. In Indonesia, there are 7,828 new cases of bladder cancer each year, which cause 3,885 deaths. The survival of bladder cancer patients highly depends on many factors. Objective: To identify the factors that influence the 5-year survival rate of patients with bladder cancer at zainoel abidin hospital. Method: An analytical one year study using a retrospective cohort design to analize the factors affecting the 5-year survival rate of bladder cancer patients for 5 years, starting from 2015 until 2019 with medical record data. Result: The average age of the 151 patients was 59±11.9 years, and 126 patients (83,4%) were male. The majority 105 patients (69.54%) were under 65 years old. A total of 127 patients (84.11%) were smokers, 65 patients (43%) with high school degree, 50 patients (33,11%) were self-employed, 96 patients (63.58%) is underweight BMI. Based on stadium of bladder cancer, the majority of patients (34.44%) had T3, and the most common treatment (78.81%) was TURBT and refused to radikal cystectomy. Patient survival rates were influenced by age (P value = 0.00), education level (P value = 0.003), occupation (P value =0,01), treatment (P value = 0,005), and T category (P value = 0.00). Conclusion: Age, education level, occupation, treatment and T category have a significant impact on bladder cancer patients survival rate. Keywords: Bladder cancer, 5-years survival, Age, Education level, Occupaton, Smokers, BMI, T Category, Treatment.
Emerging Non-Invasive Therapies and Their Effectiveness in the Comprehensive Management of Prostate Cancer: a Systematic Review of Current Trends and Future Directions Aditya, Tengku Rizky; Ismy, Jufriady
Journal La Medihealtico Vol. 6 No. 3 (2025): Journal La Medihealtico
Publisher : Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journallamedihealtico.v6i3.2159

Abstract

Prostate cancer remains one of the most prevalent cancers globally, with traditional treatments like surgery, chemotherapy, and radiation often causing significant side effects and lengthy recovery. This study explores emerging non-invasive therapies—such as androgen-receptor pathway inhibitors (ARPI), radioligand therapy with lutetium, immunotherapy, high-intensity focused ultrasound (HIFU), and cryoablation—evaluating their efficacy, side effects, progression-free survival (PFS), overall survival (OS), and tumor reduction. A systematic review of recent studies revealed that ARPIs and lutetium-based radioligand therapy significantly improve PFS and OS in metastatic cases. Meanwhile, HIFU and cryoablation show promise in localized prostate cancer, offering effective tumor control with shorter recovery and fewer long-term complications than surgery. Immunotherapy, notably immune checkpoint inhibitors, demonstrated efficacy in select patient groups but posed risks of immune-related adverse events. While these therapies highlight a shift toward personalized treatment—leveraging genomic and clinical markers to optimize patient care—long-term data on their outcomes and side effects remain limited. This review underscores the potential of non-invasive therapies to transform prostate cancer management by enhancing quality of life and reducing treatment burdens. However, extensive research and clinical trials are essential to validate these approaches as standard care.
Analisis Lima Tahun Angka Harapan Hidup Pada Keganasan Kandung Kemih Ismy, Jufriady; Mauny, Muhammad Puteh; Muyasir
Journal of Medical Science Vol 6 No 1 (2025): Journal of Medical Science
Publisher : LITBANG RSUDZA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55572/jms.v6i1.140

Abstract

Kanker kandung kemih adalah kanker kedua yang paling umum dan menyumbang 3,2% dari total kasus kanker di seluruh dunia. dari total kasus kanker di seluruh dunia. Di Indonesia, Kanker kandung kemih adalah kanker genitourinari kedua yang paling sering terjadi dan insidensinya meningkat 15% setiap tahunnya. Harapan hidup pasien kanker kandung kemih dipengaruhi oleh berbagai faktor, seperti usia, stadium kanker, jenis pengobatan, dan kualitas hidup pasien. Penelitian ini bertujuan untuk menganalisis angka harapan hidup pasien dengan kanker kandung kemih dan faktor-faktor risiko yang memengaruhinya, serta mengukur kualitas hidup dengan menggunakan EORTC QLQ-C30 versi 3.0. Penelitian ini menggali data pasien keganasan kandung kemih yang dirawat di RSUDZA Banda Aceh dari 2019 hingga 2023 dengan pendekatan retrospektif berdasarkan kode ICX C67.0. Hasil penelitian menunjukkan bahwa dari 157 kasus yang diambil dari sistem registrasi rekam medis RSUDZA, informasi berhasil terkumpul dari 126 pasien atau keluarganya (tingkat respons = 92%) sehingga jumlah subjek penelitian akhir 98 pasien. Analisis univariat untuk variabel seperti usia, jenis kelamin, dan beberapa karakteristik lainnya. Kedua, analisis bivariat digunakan untuk mengeksplorasi hubungan antara karakteristik pasien, seperti usia dan jenis kelamin, dengan faktor lainnya. Metode statistik yang digunakan dalam analisis bivariat disesuaikan dengan jenis data dan distribusinya. Terakhir, analisis multivariat menggunakan regresi logistik untuk mengidentifikasi faktor-faktor yang mempengaruhi ketahanan hidup pasien. Penelitian ini dilakukan di RSUD dr. Zainoel Abidin Banda Aceh, dengan tujuan untuk mengetahui faktor-faktor yang mempengaruhi prognosis pasien kanker kandung kemih. Mayoritas subjek penelitian adalah laki-laki (92,9%). Analisis mengungkapkan bahwa faktor risiko yang signifikan memengaruhi angka harapan hidup pasien adalah staging kategori T, dengan p<0,001 dan OR 146,4 (95% CI) dengan rata-rata kualitas hidup pasien yang diukur dengan EORTC QLQ-C30 versi 3.0, adalah 32,88% (SD ± 22%). Penelitian ini menggambarkan pentingnya deteksi dini dan penanganan kanker kandung kemih untuk menjaga kualitas hidup pasien dan menekankan peran kategori T dalam manajemen pasien untuk meningkatkan prognosis mereka. Hasil ini dapat membantu pengambilan keputusan klinis yang lebih baik dalam perawatan pasien kanker kandung kemih. Hasil penelitian ini khususnya menyoroti peran yang dimainkan oleh kategori T dalam manajemen pasien, yang telah terbukti memiliki pengaruh signifikan terhadap prognosis pasien.
Co-Authors Aditya, Tengku Rizky Adyasa Manggala Putra, Idham Agreno, Marshal Amirsyah, Mirnasari Andreas Bahagianto, Aditya Fajar Bangun I Y Budiman, B Dahril Darmi, Noer Faisal Dasrul Dasrul Dasrul Dasrul Deslo, Jauhari Dessy R. Emril Erdani, Ferry Ferry Erdani Furqan Hidayatullah Ibhaliswan, Andi Akbar Ikhwan, Haznur Imam Hidayat Indra Firdaus, Gugum Isa, Muntadhar Muhammad Jauhari Deslo Jufitriani Ismy Juliar Adista, Rangga Khairan, K Khalilullah, Said Alfin Liarto, Jason Limbong, Ahmad Affandi M Yusuf Maimun Syukri Mauny, Muhammad Puteh Merysia Karmila Mirnasari, Mirnasari Moh. Rasyid Ridho Muhammad Azmi Fanany Muhammad Bintang Iqbal Muhammad Ridha Muhammad Ridha Muhammad Yusuf Muslim Muslim Muyasir Nanan Sekarwana Putra, Novrianda Eka Rayyan Al Faruqi Reza Maulana Ronasky, T RR. Ella Evrita Hestiandari Safrizal Rahman Safrizal Rahman, Safrizal Said A. Khalilullah Syahmardani Ibnu Syahputra, Dian Adi T Ronasky Triyaka, Rendy Y, Bangun I Yudhi Aulia