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All Journal Journal of Natural Product and Pharmaceutical Chemistry Journal of Natural Sciences and Mathematics Research Abdimas Talenta : Jurnal Pengabdian Kepada Masyarakat Indonesian Journal of Pharmaceutical and Clinical Research International Journal Of Science, Technology & Management (IJSTM) Indonesian Journal of Applied Research (IJAR)
Siti Morin Sinaga
Department Of Pharmaceutical Chemistry, Faculty Of Pharmacy, Universitas Sumatera Utara, Jl. Tri Dharma No. 5, Kampus USU, Medan. Sumatera Utara, Indonesia 20155.
Aerospace Engineering Agriculture, Biological Sciences & Forestry Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Earth & Planetary Sciences Education Electrical & Electronics Engineering Energy Engineering Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mechanical Engineering Medicine & Pharmacology Physics Public Health Social Sciences Transportation

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Journal : International Journal Of Science, Technology

 1 
Isolation Of Chitosan From Cuttlefish Bones Ningrum, Siti Rahmi; Sinaga, Siti Morin; Harahap, Urip
International Journal of Science, Technology & Management Vol. 3 No. 3 (2022): May 2022
Publisher : Publisher Cv. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46729/ijstm.v3i3.523

Abstract

One of the potential natural resources in Indonesia is the abundance of natural resources in the marine sector. The survey results show that the sale of cuttlefish in the market indicates that the demand for cuttlefish is very high. Cuttlefish is a type of marine animal that is widely consumed by the public because of its very high protein content, but the part used from this cuttlefish is the meat, while the squid bones are discarded. Cuttlefish bone is one of the natural ingredients that contains chitin, and when the isolation process is carried out with the stages of deproteinization, demineralization, and deacetylation, it can produce chitosan compounds. The aim of the study was to isolate chitosan from cuttlefish bones. Isolation of chitosan includes 3 basic stages, namely deproteinization, demineralization, and deacetylation. Then the characteristics of chitosan from cuttlefish bones are analyzed, namely water content analysis, ash content, protein content, ninhydrin test, and FT-IR characteristics. The results of characteristic testing of 8.04% water content, 1.73% ash content, and 4.8% protein content, ninhydrin test results showed that cuttlefish bone chitosan had an amine group, and FT-IR results showed that the absorption bands of C-O and C-N groups. The conclusion of this study shows that chitosan can be isolated from cuttlefish bones.
Determination Of Vitamin C And Antioxidant Activity In Fresh Red Guava (Psidium Guajava L.) And Red Guava Commercial Fruit Juices Khairiyah, Siti; Sinaga, Siti Morin; Putra, Effendy De
International Journal of Science, Technology & Management Vol. 3 No. 4 (2022): July 2022
Publisher : Publisher Cv. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46729/ijstm.v3i4.543

Abstract

Red guava (Psidium guajava L.) has various benefits such as overcoming digestive disorders, thrush and dengue fever and can be used for anticancer herbal therapy. Red guava fruit is a fruit with the highest levels of vitamin C compared to other fruits. It contains carotenoid compounds and phenolic compounds that act as antioxidants. Red guava fruit is often processed into fruit juice drinks that are packaged in various types of packaging and distributed commercially so that people can consume red guava fruit more efficiently. Determination of vitamin C levels using the UV-Visible spectrophotometric method and the results obtained that the vitamin C content of red guava commercial fruit juice is higher than fresh red guava juice. Measurement of antioxidant activity of red guava fruit and its commercial fruit juice using ABTS methods. The results obtained in the ABTS method, fresh red guava juice and its commercial fruit juice have very strong antioxidant activity (IC50 < 50 µg/mL).
Isolation of Chitosan From Dogol Shrimp Skin (Parapenaeopsis sculptilis) Anggreini, Dea; Yuandani, Yuandani; Sinaga, Siti Morin
International Journal of Science, Technology & Management Vol. 4 No. 1 (2023): January 2023
Publisher : Publisher Cv. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46729/ijstm.v4i1.737

Abstract

In Indonesia, shrimp underwent a "cold storage" process where the heads, tails, and shells were discarded as waste. This shrimp waste could pollute the environment around the factory so it needed to be utilized. So far, shrimp shells had only been used as ingredients for making crackers, shrimp paste, and animal feed supplements. The remaining shrimp shells that had been separated were made into chitosan which was then subjected to characterization tests. The three steps of the chitosan isolation process were deproteinization, demineralization, and deacetylation. The analytical tests carried out were testing the water content, ash content, and functional groups contained in chitosan which were identified using the Fourier Transform Infra Red (FT-IR) Spectrophotometer. Based on the test results, there was a moisture content of 9.27% ??and an ash content of 1.69% in the chitosan samples made from shrimp shells. Functional groups of shrimp shell chitosan were identified using FT-IR characteristics. The -NH- group, which was represented by the N-H and O-H stretching groups, could be seen in the absorption band 1456.26 in the wave range 3000–30500. The conclusion of this study was that chitosan could be extracted from shrimp shells and meet the characterization criteria.
Phytochemical and FTIR Analysis Of Coriander Leaf Infusion As An Active Pharmaceutical Ingredient Wulandari, Suci; Sinaga, Siti Morin; Harahap, Urip
International Journal of Science, Technology & Management Vol. 4 No. 4 (2023): July 2023
Publisher : Publisher Cv. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46729/ijstm.v4i4.878

Abstract

This study reported that the sample used in the study was an infusion using fresh coriander leaves samples taken in the Lubuk Pakam area. Several studies have shown that the active components of coriander seeds are essential oils such as sabiene, myrcene, alphaterpine, ocimene, linalool, graniol, decanal, desilaldehyde, trantridecen, petroselinic acid, octadesenic acid, d-mannite, scopoletin, psimena, kamfena and felandren. These components cause coriander to have a good effect as a medicinal component. In previous studies, Linalool is believed to have antioxidant, anxiety, antibacterial (especially gram-positive) and antifungal effects. This activity is suspected because coriander contains secondary metabolites such as alkaloids, saponins, flavonoids, tannins, steroids, triterpenoids, glycosides. So this research was conducted to determine the content of secondary metabolites in coriander leaves by phytochemical screening. Phytochemical screening is a test to determine the class of chemical compounds present in coriander leaf infusion samples. Fourier transform infrared spectroscopy (FTIR) analysis was performed to find the isolating compounds in coriander leaves. The results showed that one secondary metabolite compound was negative in examining steroid secondary metabolites. The results of extract assistance with FTIR showed the presence of saponins with a molecular weight of 873.0 g/mol at a retention time of 19,287 minutes, but the peaks produced were not dominant.
Co-Authors Aminah Dalimunthe Anggreini, Dea Cintya, Henni Denny Satria, Denny Effendy De Lux Putra Effendy De Lux Putra, Effendy De Lux Fathur Rahman Furi, Mustika Ginting, Nahitma Ginting, Nahitma Harfiansyah, M. Deddy Hutabalian, Marshinta Romarta Uly Iksen, Iksen Jansen Silalahi Kevin kevin Lida Karo Karo Mursalina Mursalina Nasri Nasri, Nasri Ningrum, Siti Rahmi Putra, Effendy De Siregar, Nina Ashariani Siti Khairiyah Suci Wulandari Syukur Berkat Waruwu Urip Harahap Wardono, Sri Yosy Cinthya Eriwaty Silalahi Yuandani