Article Per Year (5 Year)
p-Index From 2020 - 2025
2.155
P-Index
This Author published in this journals
All Journal Majalah Kedokteran Bandung Jurnal Pengabdian Kepada Masyarakat (Indonesian Journal of Community Engagement) Universa Medicina Jurnal Kesehatan Manarang Jurnal Analis Kesehatan Jurnal Kesehatan Borneo Journal of Medical Laboratory Technology JURNAL INOVASI DAN PENGABDIAN MASYARAKAT INDONESIA Prosiding Seminar Kesehatan Masyarakat Prosiding Seminar Nasional Unimus Lontara Journal Of Health Science And Technology
Andri Sukeksi
Analis Kesehatan Fakultas Keperawatan dan Kesehatan Universitas Muhammadiyah Semarang
Humanities Biochemistry, Genetics & Molecular Biology Chemistry Decision Sciences, Operations Research & Management Dentistry Education Engineering Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary

Published : 16 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 16 Documents
Search

 1   2 
Differences in Alcohol Consumption Duration on Cholesterol Levels Nuroini, Fitri; Agustin, Dela Putri; Isworo, Joko Teguh; Sukeksi, Andri
PROSIDING SEMINAR KESEHATAN MASYARAKAT Vol 2 No October (2024): Proceeding of The 1st International Seminar on Public Health and Sports (IS
Publisher : Fakultas Kesehatan Masyarakat, Universitas Muhammadiyah Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26714/prosidingfkm.v2iOctober.631

Abstract

Background: Alcohol is toxic containing hydrophilic ethanol so that it easily enters the body which will be converted into acetaldehyde by aldehyde dehydrogenase (ALDH) and oxidized to acetate. Excessive acetate is converted into acetyl-CoA which is converted into fatty acids that will continue to accumulate to increase cholesterol. Consuming alcohol within 5 years with a frequency of 3-4x per week can increase cholesterol levels. The study aimed to determine the difference in the duration of alcohol consumption (≤ 5 and > 5 years) on cholesterol levels. Method: Analytic observational research with a cross-sectional approach. Samples were taken randomly from as many as 20 people who consumed alcohol ≤ 5 and > 5 years at a cafe in Salatiga. Cholesterol levels were examined using the POCT method, and then cholesterol levels were statistically analyzed using Shapiro Wil and Independent T-Test. Result: The mean cholesterol levels of respondents who consumed alcohol ≤ 5 and > 5 years were 172.30 ± 16.63 mg/dL and 236.80 ± 34.74 mg/dL, respectively. Cholesterol levels of respondents who consume alcohol ≤ 5 are still in the normal category while cholesterol levels of respondents who consume > 5 years fall into the high-risk category. Based on the statistical results, it is known that the data is normally distributed and there are differences between respondents who consume alcohol ≤ 5 years and > 5 years. Conclusion: The cholesterol levels of respondents who consumed alcohol > 5 years were higher than those who consumed alcohol ≤ 5 years.
PERBANDINGAN SATURASI OKSIGEN DIUKUR DENGAN OKSIMETRI NADI DAN ANALISIS GAS DARAH (AGD) ARTERI PADA PASIEN PPOK DI RSPAW SALATIGA Puspitaningrum, Rioni Wahyu; Sukeksi, Andri; Wahyuningtyas, Nunung Dartini
Prosiding Seminar Nasional Unimus Vol 7 (2024): Transformasi Teknologi Menuju Indonesia Sehat dan Pencapaian Sustainable Development G
Publisher : Universitas Muhammadiyah Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Penyakit Paru Obstruktif Kronik (PPOK) merupakan penyakit tidak menular dan masih menjadi masalah kesehatan global khususnya di Indonesia. Terjadinya penyempitan saluran pernapasan di interpretasikan melalui sesak napas dan penurunan saturasi oksigen dalam darah, sehingga pasien PPOK perlu dilakukan terapi dengan tetap memantau saturasi oksigen pasien. Metode pengukuran saturasi oksigen hemoglobindalam darah (SO2) dapat melalui analisis gas darah (AGD) arteri secara invasif dan pengukuran SpO2 nadi secara non invasif menggunakan oksimetri nadi dengan instrument pulse oximeter (PO). Tujuan dari penelitian ini adalah untuk mengetahui perbedaan saturasi oksigen diukur menggunakan oksimetri nadi dan analisis gas darah arteri pada pasien PPOK di RSPAW Salatiga. Desain penelitian yang digunakan crosssectional, dengan jumlah sampel penelitian adalah 66 pasien rawat inap di RSPAW. Hasil rata– rata saturasi oksigen pasien PPOK di RSPAW Salatiga yangdiperiksa menggunakan oksimetri nadi adalah 97.3% dan AGD adalah 94.4%.Sensitivitas dan spesifisitas saturasi oksigen dengan oksimetri nadi adalah 31.8%dan 86.4%. Terdapat perbedaan yang signifikan hasil saturasi oksigen diukurmenggunakan oksimetri nadi dan analisis gas darah arteri pada pasien PPOK di RSPAW Salatiga.Kata kunci : Saturasi Oksigen, Oksimetri Nadi, Analisis Gas Darah, PPOK, Sensitivitas, Spesifisitas
Hubungan Jumlah Eritrosit Dengan Nilai Laju Endap Darah Pada Perokok Konvensional Wulandari, Try; Sukeksi, Andri; Putri, Gela Setya Ayu
Prosiding Seminar Nasional Unimus Vol 7 (2024): Transformasi Teknologi Menuju Indonesia Sehat dan Pencapaian Sustainable Development G
Publisher : Universitas Muhammadiyah Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Rokok konvensional mengandung kurang lebih 4.000 senyawa kimia, salah satunya adalah karbon monoksida yang dapat menyebabkan suplai oksigen ke dalam jaringan tubuh terganggu akibat karbon monoksida yang berikatan dengan eritrosit, sehingga menyebabkan tubuh merangsang hormon eritropoietin untuk memproduksi lebih banyak eritrosit. Peningkatan jumlah eritrosit menyebabkan eritrosit lebih mudah menempel satu sama lain, sehingga memudahkan terbentuknya rouleaux dan mengakibatkan pengendapan eritrosit menjadi lebih cepat, sehingga meningkatkan nilai laju endap darah. Penelitian menggunakanpenelitian kuantitatif. Populasi yang diteliti dalam penelitian adalah mahasiswa DIV analis kesehatan angkatan 2021 dan 2022 Universitas Mohammadiyah Semarang. Pengambilan sampel dilakukan secarapurposive sampling sebanyak 30 sampe. Hasil penelitian menunjukkan hasil jumlah eritrosit pada perokokkonvensional diperoleh 4,5 - 5,5 sebanyak 22 responden (73,33%), sedangkan hasil jumlah eritrosit >5,5sebanyak 8 responden (26,67%) dan hasil nilai LED pada perokok konvensional diperoleh <= 10 sebanyak23 responden (76,67%), sedangkan nilai LED >10 sebanyak 7 responden (23,33%). Korelasi antara jumlaheritrosit dengan LED pada perokok konvensional dengan menggunakan uji statistik  Pearson diperoleh hasilp-value sebesar 0,000. Kesimpulan dari penelitian ini yaitu terdapat hubungan antara jumlah eritrositdengan LED pada perokok konvensional.  Kata Kunci : Jumlah eritrosit, laju endap darah, dan merokok.
Potensi Ekstrak Etanol Daun Sirih (Piper Betle L.) Sebagai Pengganti ADP (Adenosine Diphosphate) Pada Pemeriksaan Agregasi Trombosit Sukeksi, Andri; Rahmawati, Rizqi Yogania
Lontara Journal of Health Science and Technology Vol. 2 No. 1 (2021): Ilmu dan Teknologi Kesehatan
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Politeknik Muhammadiyah Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53861/lontarariset.v2i1.184

Abstract

Adenosine diphosphate (ADP) reagent is often used in the examination of platelet aggregation, yet has limitations in terms of price and availability. Natural source namely betel leaf (Piper betle L.) are believed to be used as a substitute for ADP because betel leaf have the characteristics of styptic (to resist bleeding), vulnerary (to heal skin wounds), and anti-inflammatory (to preserve inflammation) (Moeljanto & Mulyono, 2003). The aim of this study was to determine the potential of betel leaf on the examination of platelet aggregation. The method used in this research included the betel leaf extraction using ethanol as solvent with an evaporator. The extract obtained was used as a substitute for the ADP reagent in platelet examination in the form of determining the percentage of platelet aggregation in 16 human blood samples, with a population of students at the University of Muhammadiyah Semarang. The final results showed that the addition of betel leaf extraction to the 16 blood samples examined gave an average value of platelet aggregation percentage which was higher (65%) than the mean value of platelet aggregation using ADP reagent mixing (57%). Both results fall within the normal value range, namely 50-70%. It can be concluded that betel leaf extract has the potential to be used as a replacement reagent for ADP in the process of examining platelets, especially in determining the percentage value of platelet aggregation.
Effect Of Donor Blood Storage Period on Hemoglobin Levels and Erythrocyte Cell Morphology Wulandari, Eka Wahyu Putri; Afriansyah, Muhammad Ardi; Sukeksi, Andri
Jurnal Kesehatan Manarang Vol 10 No 2 (2024): August 2024
Publisher : Politeknik Kesehatan Kemenkes Mamuju

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33490/jkm.v10i2.929

Abstract

Blood is a body fluid whose stability can be influenced by both internal and external factors such as storage period. Storing blood specimens for a long time can cause changes in the physiological condition of blood cells such as color, size, shape and cell formation. This study aims to determine the effect of the storage period for donor blood specimens at UTD RSUP dr. Kariadi Semarang on hemoglobin levels and erythrocyte morphology. The research design is an experiment using a modified Time Series design with a pre and posttest control group design. The samples in this study were CPDA-1 (Citrate Phosphate Dextrose Adenine) donor blood specimens at the Blood Transfusion Unit of RSUP dr. Kariadi Semarang. Observation of erythrocyte cell morphology using blood smear preparations (SHD). Primary data was taken from the results of measurements of hemoglobin levels and observations of erythrocyte cell morphology with blood specimens examined directly (day 0) and storage days 1, 2, and 3. Analysis of research data used the One-way Anova statistical test. The results of the One-Way Anova test showed that there was a significant difference in hemoglobin levels on the 3rd day of donor blood storage (p-value 0.000). The results of the evaluation of erythrocyte cell morphology showed that there were abnormalities in crenation morphology on the 3rd day of storage. Blood specimens should be processed immediately after they leave the body because the condition of the blood cells is still stable and optimal for use in laboratory tests.
Pengaruh Penundaan Sampel Terhadap Nilai Agregasi Trombosit Darah Sitrat Pada Suhu Ruang (25ºC) Putri, Gela Setya Ayu; Ulya, Iha Himatul; Sukeksi, Andri
Borneo Journal of Medical Laboratory Technology Vol. 8 No. 1 (2025): Borneo Journal of Medical Laboratory Technology
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjmlt.v8i1.10651

Abstract

Pemeriksaan agregasi trombosit merupakan pemeriksaan penting untuk mengevaluasi fungsi trombosit. Pemeriksaan ini bersifat sangat sensitif dan dipengaruhi oleh berbagai faktor, seperti konsentrasi sodium sitrat, jumlah trombosit, suhu penyimpanan, dan waktu penundaan pemeriksaan. Metode pemeriksaan dapat dilakukan secara otomatis maupun manual, salah satunya menggunakan metode Velaskar. Permasalahan yang sering terjadi di laboratorium adalah penundaan pemeriksaan, yang berpotensi menyebabkan kerusakan fungsi trombosit sehingga meningkatkan persentase agregasi. Penelitian ini bertujuan mengetahui perbedaan persentase agregasi trombosit berdasarkan variasi waktu penundaan sampel darah sitrat pada suhu ruang (25°C). Desain penelitian yang digunakan adalah analitik eksperimental. Sampel darah vena diperoleh dari enam responden, kemudian dibagi ke dalam empat kelompok perlakuan yaitu kelompok segera diperiksa (kontrol), ditunda 2 jam, 3 jam, dan 4 jam. Agregasi trombosit diperiksa menggunakan metode Velaskar dengan pewarnaan Giemsa. Data dianalisis dengan One-Way Anova dan Post-Hoc. Hasil penelitian menunjukkan rata-rata persentase agregasi trombosit pada kelompok kontrol, penundaan 2 jam, 3 jam, dan 4 jam berturut-turut adalah 56,3%, 59,6%, 71,5%, dan 75,5%. Analisis One-Way Anova menunjukkan nilai signifikansi 0,000 (p<0,05), menandakan adanya perbedaan bermakna antar kelompok. Uji Post Hoc mengungkap bahwa tidak terdapat perbedaan signifikan antara kelompok kontrol dan penundaan 2 jam (p>0,05), sedangkan penundaan 3 dan 4 jam menunjukkan perbedaan yang signifikan (p<0,05). Dengan demikian, pemeriksaan agregasi trombosit masih dapat dilakukan hingga 2 jam setelah pengambilan sampel pada suhu ruang, namun penundaan lebih dari 2 jam tidak direkomendasikan karena dapat memengaruhi akurasi hasil.
Co-Authors Afriansyah, Muhammad Ardi Agustin, Dela Putri Ana Hidayati Mukaromah Budi Santosa Budi Santosa Gela Setya Ayu Putri Handayani, Sri Puji Henna Ria Sunoko, Henna Ria Janah, Inayah Qori Nur Jimat, Resi Tondho Joko Teguh Isworo Kadarwati, Ari Maolida, Nurul Meturan, Dessy Marselina Meyliana, Adinda Noor Fadillah Nuroini, Fitri Pratama, Aji Sukma Puspitaningrum, Rioni Wahyu Ragil Saptaningtyas, Ragil Rahmawati, Rizqi Yogania Sari, Sri Mayang Stalis Norma Ethica Ulya, Iha Himatul Wahyuningtyas, Nunung Dartini Wulandari, Eka Wahyu Putri Wulandari, Try