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All Journal JURNAL BISNIS STRATEGI JDM (Jurnal Dinamika Manajemen) JBTI : Jurnal Bisnis : Teori dan Implementasi Anterior Jurnal Indonesian Journal of Community Services Munaddhomah: Jurnal Manajemen Pendidikan Islam Sibatik Journal : Jurnal Ilmiah Bidang Sosial, Ekonomi, Budaya, Teknologi, Dan Pendidikan eCo-Fin AKADEMIK: Jurnal Mahasiswa Ekonomi & Bisnis Borobudur Management Review Journal of Accounting and Finance Management (JAFM) Journal of Artificial Intelligence and Digital Business Cerdika: Jurnal Ilmiah Indonesia Jurnal Ilmiah Sultan Agung PESHUM Al-Hayat: Journal of Islamic Education Folia Medica Indonesiana
Heru Sulistyo
Faculty of Economic, Sultan Agung Islamic University, Indonesia
Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Electrical & Electronics Engineering Engineering Health Professions Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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Examination of Micro Vascular Density on Metastatic Colorectal Cancer of RAS Mutant-Type as Anti Vegf Therapy Predictor Sulistyo, Heru; Budipramana, Vicky Sumarki
Folia Medica Indonesiana Vol. 57, No. 2
Publisher : Folia Medica Indonesiana

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Abstract

According to the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) on Colon Cancer Version 2.2019, mCRC patients with mutant type RAS were treated with anti-VEGF. However, the use of the targeting therapy still had inconsistent results. Neoangiogenesis studies had been used as a basis to assess the prognosis of mCRC. Microvascular density (MVD) had become the morphological gold standard to assess neovascularization in human tumors. This study proved the existence of low microvascular density (MVD) in mCRC patients with mutant type RAS status as a predictor of failure of anti-VEGF therapy. There were 29 patients at Dr. Soetomo Academic Hospital from 2015-2018 who had their RAS status checked and tested for microvascular density (MVD). The results of this study were analyzed using SPSS 23.0. In the Mutant-type of RAS group, this study examined microvascular density (MVD). 11 (73%) research subjects with high MVD scores and 4 (27%) research subjects had low MVD scores. Besides, 27% microvascular density (MVD) was low, in the mutant-type of RAS mCRC patient which could be a predictor factor for the failure of anti-VEGF therapy.
Pengaruh Customer Experience Terhadap Repurchase Intention Melalui Customer Loyalty Pada Pengguna Shopeefood Adiani, Azza Khisnu; Sulistyo, Heru
RIGGS: Journal of Artificial Intelligence and Digital Business Vol. 5 No. 1 (2026): Februari - April
Publisher : Prodi Bisnis Digital Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/riggs.v5i1.6171

Abstract

Penelitian ini bertujuan untuk menguji dan menganalisis pengaruh customer experience terhadap repurchase intention dengan customer loyalty sebagai variabel mediasi pada pengguna layanan ShopeeFood di kalangan mahasiswa Universitas Islam Sultan Agung Semarang. Jenis pendekatan dalam penelitian ini yaitu menggunakan pendekatan kuantitatif dengan metode survei. Teknik pengumpulan data dilakukan melalui penyebaran kuesioner kepada responden yang merupakan pengguna aktif ShopeeFood dan telah melakukan pembelian lebih dari dua kali. Jumlah sampel yang diambil dalam penelitian ini sebanyak 100 responden yang ditentukan menggunakan teknik purposive sampling. Data yang telah terkumpul dianalisis menggunakan analisis jalur (path analysis) untuk menguji hubungan antarvariabel serta peran mediasi customer loyalty dalam model penelitian. Hasil penelitian menunjukkan bahwa customer experience berpengaruh signifikan terhadap customer loyalty, dan customer loyalty memiliki pengaruh signifikan terhadap repurchase intention. Namun demikian, customer experience tidak terbukti memiliki pengaruh signifikan secara langsung terhadap repurchase intention. Temuan ini mengindikasikan bahwa customer loyalty berperan sebagai variabel mediasi yang memperkuat hubungan antara customer experience dan repurchase intention. Penelitian ini memberikan kontribusi teoretis dalam pengembangan literatur pemasaran jasa digital, khususnya pada konteks layanan online food delivery. Selain itu, hasil penelitian ini diharapkan dapat menjadi bahan pertimbangan praktis bagi penyedia layanan ShopeeFood dalam merancang strategi peningkatan loyalitas pelanggan. Penelitian selanjutnya disarankan untuk menambahkan variabel lain yang relevan guna memperkaya model penelitian dan memperdalam pemahaman mengenai perilaku konsumen digital.
Co-Authors ., Nurhidayati Adiani, Azza Khisnu Aniek, Sri Anita Rahayuningsih, Anita Ayuni, Sri Ayuni, Sri Azhar, Syafrudin Aulia Budhi Cahyono Budipramana, Vicky Sumarki Fibriantoro, Dedy Gunarto Gunarto Henny Pratiwi Adi Ibnu Khajar Ikke Oktavianti, Renita Kirana, Putricia Lutfi Nurcholis Marno Nugroho Mulya Noviana, Nana Mulyana Mulyana Nunung Ghoniyah Nurdin, Muh. Nur Islam Oetami, Elok Retno Pamungkas, Gufa Bagus Puspitaningrum, Putri Febiana Rushami Zien Yusoff Sahni, Sahni Saputri, Pungky Lela Setiyarti, Tettie Solikhin, Muhammad Sri Anik, Sri Subiyantoro Sundari, Pipit Suparman Suparman Uttami, Regitasari Setyaning Zainal Alim Adiwijaya, Zainal Alim