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All Journal Medical Journal of Indonesia Narra J Makara Journal of Health Research Kesmas: Jurnal Kesehatan Masyarakat Nasional (National Public Health Journal)
Din Syafruddin
Eijkman Institute for Molecular Biology
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Journal : Medical Journal of Indonesia

 1 
Malaria and Anopheles spp in the villages of Salubarana and Kadaila, Mamuju District, South Sulawesi Province, Indonesia Nurdin, Armyn; Syafruddin, Din; Wahid, Isra; Noor, Nur N.; Sunahara, Toshihiko; Mogi, Motoyoshi
Medical Journal of Indonesia Vol 12, No 4 (2003): October-December
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (208.954 KB) | DOI: 10.13181/mji.v12i4.119

Abstract

Malaria epidemiology in Salubarana and Kadaila villages, Mamuju District, South Sulawesi Province, Indonesia was studied from July-December 2002 to obtain baseline data related to the parasite, mosquito vector, human host, and environmental factors. Monthly malariometric surveys conducted during the six- month period revealed a relatively high prevalence of malaria in Kadaila in comparison to Salubarana. Kadaila was mainly inhabited by migrants from Java, Bali, Lombok, and from other districts of South Sulawesi. Salubarana, on the other hand, was inhabited mainly by indigenous Mandarese. Analysis of 1,113 blood smears taken from individuals randomly involved in the survey revealed 59 positive samples, consisting of Plasmodium falciparum or P. vivax. These two species predominated the samples examined and were occasionally found as mixed infection. Anopheles barbirostris was confirmed as a vector for malaria in this area whereas 7 other species An. barbumbrosus, An. parangensis, An. vagus, An. crawfordi, An.pseudobarbirostris, An. Tessellatus, and An. subpictus should be considered as potential vectors. The first mentioned species predominated, using mainly riverbeds and ground pools as breeding places with a habit of indoor or outdoor resting. These findings could be useful for establishing evidence-based malaria control program in the area. (Med J Indones 2003; 12: 252-8) Keywords: malaria epidemiology, parasite, vectors, environmental factors, Indonesia
Malaria in Jayapura District, Papua Province, Indonesia and resistance to sulfadoxine-pyrimethamine Sorontou, Yohanna; Asih, Puji B.S.; Wanandi, Septelia I.; Ramelan, Wahyuning; Syafruddin, Din
Medical Journal of Indonesia Vol 16, No 1 (2007): January-March
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (269.135 KB) | DOI: 10.13181/mji.v16i1.254

Abstract

Malaria poses a major public health problem in Papua. The rapid spread of drug-resistant parasites and deterioration of the malaria control program following the monetary crisis and civil strife in the late 90’es have worsened the malaria situation in many areas of Papua. To re-assess the current magnitude of malaria problem, a malariometric survey was conducted in three sub-districts of Jayapura District, as well as antimalarial drug sensitivity test using sulfadoxine-pyrimethamine (SP) at the outpatient clinics of Abepura General Hospital (RSU), Hamadi Primary Health Center and Panti Asuhan Katolik Clinics, Sentani, Jayapura District, Papua Province. Screening of 543 subjects in three sub-districts revealed 185 malaria positive subjects, either with P. falciparum, P. vivax or mixed of the two species. All of the malaria cases were asymptomatic. In the SP drug sensitivity test, of the 56 subjects involved, 32 were classified as early treatment failure and two subjects were classified as late treatment failure. The remaining 22 subjects were classified as adequate clinical and parasitological response (ACPR). These results indicated that the surveyed area has a high malaria prevalence and treatment failure to SP and therefore alert to the need of deploying new antimalarial regiment that suit the remote setting. (Med J Indones 2007; 16:32-8) Keywords: malaria, sulfadoxine-pyrimethamine (SP) resistance, Jayapura District, Indonesia
Co-Authors Ahmad Safrudin Ahmed, Rukhsana Amru, Khaeriah Armyn Nurdin Asih, Puji B S Asih, Puji BS. Bukhari, Agussalim Dewayanti, Farahana Kresno Djaharuddin, Irawaty Halik, Handayani Haryoto Kusnoputranto Hasyim, Ammar A. Irawati, Yana IRFAN IDRIS Isra Wahid Itani, Kei Iyori, Mitsuhiro Koning, Korrie De Limato, Ralalicia Miladi Kurniasari Motoyoshi Mogi Nakamura, Kurumi Nur N. Noor Nurisyah, Sitti Permana, Dendi Hadi Puji B.S. Asih Risandi, Rifqi Septelia I. Wanandi Sitorus, Alfred Sudirman Nasir Syahrani, Lepa Toshihiko Sunahara Tulloch, Olivia Umar Fahmi Achmadi Wahyuning Ramelan Wangsamuda, Suradi Yohanna Sorontou Yoshida, Shigeto Yusuf Yenni Zainal, Kartika H.