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All Journal PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Jurnal EDUCATIO: Jurnal Pendidikan Indonesia Jurnal Farmasi dan Sains Indonesia (JFSI) Jurnal Abdimas Bina Bangsa INDRA: Jurnal Pengabdian kepada Masyarakat Sinteza Jurnal Pengabdian Inovasi Masyarakat Indonesia Jurnal Sains dan Kesehatan Lentera Negeri JPEPT
Erma Ewisa Oktresia
Prodi Farmasi, Fakultas Kesehatan, Universitas Hamzanwadi, Lombok, Indonesia
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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Uji Aktivitas Ekstrak Etanol Kulit Buah Rambutan (Nephelium lappaceum L.) sebagai Penurun Kadar Asam Urat Tikus yang Diinduksi Jus Hati Ayam Sasmita, Yulinda Dinar; Oktresia, Erma Ewisa; Rafsanjani, Arief
Sinteza Vol. 1 No. 2 (2021): August
Publisher : Universitas Hamzanwadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29408/sinteza.v1i2.4449

Abstract

Asam urat adalah hasil akhir dari katabolisme (pemecahan) suatu zat yang bernama purin. Kadar asam urat normal pada laki-laki dewasa adalah sekitar 2-7,5 mg/dL, sementara pada wanita yang sudah dewasa adalah 2- 6,5 mg/dL. Peningkatan kadar asam urat diatas normal dapat menyebabkan penumpukan Kristal asam urat di jaringan. Xantin oksidase merupakan enzim yang berperan dalam mengkatalis oksidasi hipoxantin menjadi xantin dan menjadi asam urat. Penghambatan xantin oksidase menjadi target untuk menurunkan produksi asam urat. Penelitian ini bertujuan untuk menguji aktivitas ekstrak etanol dalam menurunkan kadar asam urat tikus yang diinduksi jus hati ayam. Penelitian ini merupakan penelitian eksperimental dengan desain kelompok pre dan posttest. Kulit rambutan diekstraksi menggunakan metode maserasi dengan menggunakan pelarut etanol 70%. Hasil penelitian menunjukkan bahwa ekstrak etanol kulit buah rambutan mampu menurunkan kadar asam urat tikus yang diinduksi jus hati ayam secara signifikan (p<0,05 Ekstrak etanol kulit buah rambutan dosis 3 memiliki kemampuan menurunkan kadar asam urat tikus yang lebih baik dibandingkan kelompok kontrol positif (Allopurinol). Ekstrak etanol kulit buah rambutan mengandung senyawa plavonoid, tanin, alkaloid, saponin dan terpenoid.
Gambaran Tingkat Kepuasan Pasien terhadap Pelayanan Informasi Obat di Apotek Wilayah Lombok Timur Hartono, M. Herry; Oktresia, Erma Ewisa; Sovia, Fitriwati
Sinteza Vol. 3 No. 2 (2023): August
Publisher : Universitas Hamzanwadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29408/sinteza.v3i2.18969

Abstract

Pharmaceutical services are a direct and responsible service to patients. One of the pharmaceutical service activities that align with the concept of pharmaceutical care is found in the quality of Drug Information Services (PIO) in pharmacies. The aim of this research is to determine the implementation of DIS based on the Indonesian Minister of Health Regulation No.73 of 2016 in pharmacies in the East Lombok region. This study is observational descriptive using quantitative analysis in the form of calculating the percentage of Respondent Achievement Level (TCR). Data was collected using a questionnaire covering eight activities that pharmacists should undertake when providing drug information, which were subsequently used as indicators. Sample selection was done through purposive sampling with a minimum of 96 samples. Based on the research results, the TCR percentage values for the indicators were as follows: information on drug efficacy at 78% with a good category; dosage form at 78% with a good category; usage instructions at 75% with a good category; drug dosage at 74% with a good category; side effects at 74% with a good category; drug storage at 74% with a good category; safety for pregnant and nursing mothers at 46% with a fair category; information on drug prices obtained a score of 90% with a very good category. The average TCR score for the 8 indicators was 73.3% with a good category in providing drug information services in accordance with the Indonesian Minister of Health Regulation No.73 of 2016 in pharmacies in the East Lombok region.
Analisis Efektivitas Biaya Penggunaan Insulin Lantus dan Apidra di RSUD Dr. R. Soedjono Selong Oktresia, Erma Ewisa; Sovia, Fitriwati; Ramadhan, Leny; Ramadani, Lalu Khilal
Sinteza Vol. 4 No. 2 (2024): August
Publisher : Universitas Hamzanwadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29408/sinteza.v4i2.26475

Abstract

Indonesia is one of the countries with the highest number of type II diabetes mellitus patients in the world, reaching 10.7 million people. Diabetes mellitus requires long-term treatment to control patients' blood glucose levels. The types of therapy used vary, leading to differences in costs and treatment outcomes. The use of insulin is a significant issue in diabetes mellitus therapy, especially at RSUD Dr. R. Soedjono, concerning its cost-effectiveness and therapeutic efficacy. This study aims to analyze the cost-effectiveness of using Lantus and Apidra insulin therapies.This research is an observational analytic study with a cross-sectional design, and data collection was conducted retrospectively at RSUD Dr. R. Soedjono Selong. The sample selection was based on predetermined inclusion and exclusion criteria. Observations were made on the Length of Stay (LOS) and Direct Medical Cost (DMC) for each sample. Based on LOS and DMC data, the Average Cost-Effectiveness Ratio (ACER) was calculated. The results showed that the average LOS for Lantus insulin use was 4 days, while for Apidra insulin use, it was 5 days. The average DMC for Lantus insulin was Rp.2,395,734, while for Apidra insulin, it reached Rp. 2,590,218. Based on LOS and DMC data, the ACER value for Lantus insulin was Rp 598,934/day, while for Apidra insulin, it was Rp 518,043/day. The use of Apidra insulin is more cost-effective because it has a lower ACER value.
Formulasi dan Uji Aktivitas Antibakteri Sediaan Mouthwash Fraksi Metanol Daun Seledri (Apium graveolens L.) terhadap Pertumbuhan Bakteri Streptococcus mutans Penyebab Karies Gigi Zulhijjati, Mirzalina; Yuliana, Tri Puspita; Fatmayanti, Baiq Risma; Oktresia, Erma Ewisa
Sinteza Vol. 6 No. 1 (2026): February
Publisher : Universitas Hamzanwadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29408/sinteza.v6i1.31994

Abstract

Streptococcus mutans is a bacterium found in the human oral cavity and is the primary cause of tooth decay. The effects of Streptococcus mutans bacteria can be eliminated with mouthwash formulated with natural ingredients, one of which is celery leaves, which are known to have antibacterial properties against the growth of Streptococcus mutans. The purpose of this study was to determine the best concentration of a mouthwash formulation using the methanol fraction of celery leaves based on the results of the physical properties evaluation test and to determine the antibacterial activity of a mouthwash formulation using the methanol fraction of celery leaves in inhibiting the growth of Streptococcus mutans bacteria. This study was a quantitative study using a laboratory experimental method with a posttest-only control group design. This study is a quantitative study using a laboratory experiment method with a posttest-only control group design by observing the area of ​​the inhibition zone as the dependent variable. The area of ​​the inhibition zone of each formula was compared with the control using the ANOVA test. The results of the physical properties evaluation test, including ogrnanoleptic tests, pH tests, homogeneity tests, specific gravity tests, and cycling tests, met the requirements for good physical quality. The highest antibacterial activity results were found in formula III with a concentration of 1.5% celery leaf methanol fraction with an average inhibitory power of 23.63 mm with a Very Strong category.
Tingkat kunjungan masyarakat pada pelayanan posyandu keluarga di desa Toya, Nusa Tenggara Timur Hartini Haritani; Sulistia Ardyati; Erma Ewisa Oktresia; Fitriwati Sovia; Muhammad Zainul Majdi; Atiaturrahmaniah Atiaturrahmaniah; Baiq Aryani Novianti
Lentera Negeri Vol. 3 No. 1 (2022): Lentera Negeri
Publisher : Indonesian Institute For Counseling, Education and Therapy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29210/99360

Abstract

Posyandu cadres are the driving force for the implementation of family posyandu services, both in moving targets, services and reporting. With the changing level of posyandu to a family type of this system increases the workload of posyandu cadres, the competence and skills of cadres need to be improved through training and mentoring. The data obtained was qualitative data with descriptive analysis method.  Data collection was carried out by conducting observations, interviews and technical training to posyandu cadres with the aim of providing knowledge about family posyandu services, and basic skills at tables 1 to table 8 for cadres so that the presence of this small group of people could increase the number of targeted visits to posyandu.  The results obtained from this activity were: the number of visits by pregnant women, toddlers and the elderly had increased. However, the strategy was needed to increase youth's interest in posyandu according to the number of visits by teenagers.
Formulation and Evaluation of the Physical Properties of Clay Mask Containing Ethanol Extract of Kenikir (Cosmos caudatus) Leaves Puspawan Hariadi; Rina Sri Apriani; Baiq Maylinda Gemantari; Tri Puspita Yuliana; Erma Ewisa Oktresia; Fitriwati Sovia
Journal of Pharmacology Experiment and Pharmaceutical Technology Vol. 1 No. 2 (2025): JPEPT
Publisher : DSM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.64015/jpept.v1i2.19

Abstract

The demand for natural-based cosmetic products continues to increase due to their perceived safety and minimal side effects. Kenikir leaves (Cosmos caudatus Kunth) are known to contain active compounds such as flavonoids, tannins, and phenols, which have antioxidant potential and can be utilized in facial mask preparations. This study aims to formulate a clay mask preparation from the ethanol extract of kenikir leaves and evaluate its physical properties. The extract was obtained through maceration using 96% ethanol, and then formulated into three concentrations: F1 (0.5%), F2 (1%), and F3 (2%). The evaluation of the preparation included organoleptic tests, adhesion test, spreadability test, and pH measurement. The results showed that F1 had a pH of 6, adhesion time of 2 seconds, and spreadability of 5.3 cm. F2 had a pH of 6, adhesion time of 2 seconds, and spreadability of 5.2 cm. F3 had a pH of 6, adhesion time of 4.6 seconds, and spreadability of 5 cm. The evaluation results indicated that all clay mask formulations met the physical quality criteria for clay masks.
Co-Authors Abdul Rahim Akbar, Farid Ansori, Ilham Arief Rafsanjani Atiaturrahmaniah Atiaturrahmaniah Baiq Aryani Novianti Baiq Maylinda Gemantari Baiq Risma Fatmayanti Ersi Arviana Ihsan Fitri, Sri Wardiatul Fitriwati Sovia Hardiyanti, Novi Hartini Haritani Hartono, M. Herry Hayyinatusolehah Hayyinatusolehah Immawati, Herlina Leny Ramadhan Mehratul, Nuniq Muhammad Zainul Majdi Muhlisun Azim Ningrum, Novi Stia Nisa, Ulyatin Novi Hardiyanti Nurwarini, Selsi Puspawan Hariadi Rahman, Rizky Alita Ramadani, Lalu Khilal raudatul jannah Riki Riki Rina Sri Apriani Sasmita, Yulinda Dinar Sulistia Ardyati Sulistia Ardyati Tri Puspita Yuliana Yuyun Febriani Zaiki, Destia Sipa Zulhijjati, Mirzalina