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All Journal CAKRA KIMIA (Indonesian E-Journal of Applied Chemistry) Jurnal Kimia (Journal of Chemistry) Jurnal Ilmu Lingkungan Disease Prevention and Public Health Journal Pharmaciana: Jurnal Kefarmasian Jurnal Riset Kesehatan BIOMA : Jurnal Biologi Makassar Wikrama Parahita : Jurnal Pengabdian Masyarakat Jurnal Manajemen Kesehatan Yayasan RS.Dr. Soetomo Martabe : Jurnal Pengabdian Kepada Masyarakat Jurnal Media Sains Jurnal ABDINUS : Jurnal Pengabdian Nusantara Jurnal Peduli Masyarakat Indonesian Journal of Global Health research Jurnal Ilmiah Medicamento Poltekita: Jurnal Pengabdian Masyarakat INDRA: Jurnal Pengabdian kepada Masyarakat Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Makara Journal of Science Jurnal Bioconcetta Benzena Pharmaceutical Scientific Journal UNBI Mengabdi Bali International Scientific Forum Jurnal Info Kesehatan Jurnal Ilmiah Teknologi Pertanian Agrotechno
Ni Putu Widayanti
Universitas Bali Internasional
Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Electrical & Electronics Engineering Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Green synthesis of silver nanoparticles with sintrong leaf infusion (Crassocephalum crepidioides) as antibacterial activity I Wayan Tanjung Aryasa Aryasa; Putu Diah Darmayanti; Ni Putu Widayanti
Pharmaciana Vol. 16 No. 1 (2026): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/pharmaciana.v16i1.31320

Abstract

Substances with dimensions in the 1–100 nm range are categorized as nanoparticles. Physicochemical properties differ markedly from those of conventional bulk materials. Silver is particular interest for its well-documented antimicrobial capacity, which is greatly amplified when silver is reduced to nanoparticle size. AgNPs have been developed as effective agents for combating bacterial and fungal infections. Among available synthesis routes, green biosynthesis has gained prominence as a clean and sustainable option. It harnesses the reduction potential of plant-derived metabolites to produce nanoparticles without generating harmful waste. The antimicrobial efficacy of the synthesized AgNPs was assessed against Staphylococcus aureus and Escherichia coli via the agar diffusion method, and characterization was carried out using PSA and UV-Vis spectrophotometry at repeated intervals. PSA measurements indicated that raising AgNO₃ from 1 to 2 mM produced nanoparticles with average diameters of 63.1 nm and 52.0 nm, respectively. UV-Vis data collected from the first day showed an ascending then descending trend, with AgNP-characteristic absorption peaks in the 422–452 nm zone. Antibacterial testing produced distinct inhibition: zone diameters against Staphylococcus aureus were AgNPs 1 10.57 ± 0.02 mm, AgNPs 2 10.21 ± 0.35 mm, AgNPs 3 10.98 ± 0.20 mm, and AgNPs 4 11.02 ± 0.51 mm, while inhibition against Escherichia coli yielded AgNPs 1 8.93 ± 0.04 mm, AgNPs 2 8.80 ± 0.10 mm, AgNPs 3 9.07 ± 0.07 mm, and AgNPs 4 9.31 ± 0.43 mm. Overall, these data confirm the antibacterial potential of AgNPs biosynthesized from sintrong leaf infusion effectively inhibited both tested bacterial organisms.
Co-Authors Adie Wahyudi Oktavia Gama Ayu Saka Laksmita W Darma, I Gede Wahyu Surya Desak Putu Risky Vidika Apriyanthi Dewi Puspita Apsari Dwijastuti, Ni Made Sri Fitriayu Refi, Maria Agustina I GUSTI AGUNG AYU SATWIKHA DEWI - I Gusti Kamasan Arijana I Nyoman Suarsana I Wayan Tanjung Aryasa I Wayan Tanjung Aryasa Aryasa I. A. R. Astiti Asih Iriani, Yulidia Iswari, Ni Wayan Gita Jeharu, Sofiana Agustin L., Yulidia Iriani Muhammad Nanda Aprilianto Ni Luh Desyani Ni Made Puspawati Ni Putu Rahayu Artini Ni Putu Widiantari Oktaviani, Fatikhatul Putri Pramesti, Ayu Christin Putu Diah Darmayanti Putu Yudhistira Budhi Setiawan Risky Vidika A Risky Vidika Apriyanthi Sashmita, Geby Septiasari, Ni Putu Senshi Sutrisna Putra, I Gusti Putu Agus Ferry Vidika A, Risky Vidika, Desak Putu Risky Widnyani, Ni Made Wintariani, Ni Putu WIWIK SUSANAH RITA Yenni Ciawi Yulidia Iriani Yulidia Iriani L.