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All Journal Jambi Medical Journal : Jurnal Kedokteran dan Kesehatan Majalah Kedokteran Bandung Althea Medical Journal Indonesian Journal of Urology Indonesian Journal of Obstetrics & Gynecology Science Majalah Patologi Indonesia Bioscientia Medicina : Journal of Biomedicine and Translational Research Jurnal Ilmu Bedah Indonesia Bioscientia Medicina : Journal of Biomedicine and Translational Research Jurnal Locus Penelitian dan Pengabdian Eduvest - Journal of Universal Studies
Anglita Yantisetiasti
Department Of Anatomical Pathology, Faculty Of Medicine/Padjadjaran University, Hasan Sadikin Hospital, Bandung.
Aerospace Engineering Automotive Engineering Biochemistry, Genetics & Molecular Biology Computer Science & IT Decision Sciences, Operations Research & Management Electrical & Electronics Engineering Health Professions Immunology & microbiology Mathematics Medicine & Pharmacology Neuroscience Public Health Social Sciences

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A Rare Primary Breast Angiosarcoma with Bone Metastasis: A Case Report Sari , Rupita; Kiki A. Rizki; Anglita Yantisetiasti
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 8 No. 10 (2024): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v8i10.1095

Abstract

Background: Angiosarcoma is a rare and aggressive malignant tumor originating from endothelial cells. Primary breast angiosarcoma (PBA) is exceedingly uncommon, accounting for less than 1% of all breast malignancies. Bone metastasis from PBA is even rarer, making it a unique clinical entity. Case presentation: We present the case of a 37-year-old woman who initially presented with a rapidly enlarging breast mass. A biopsy confirmed the diagnosis of PBA, and she underwent a modified radical mastectomy followed by radiotherapy. Seventeen months later, she developed progressive lower extremity weakness and urinary and bowel incontinence. Imaging revealed a spinal metastasis at the Th4-Th6 level. Biopsy and immunohistochemistry confirmed metastatic angiosarcoma. The patient underwent laminectomy and posterior stabilization. Conclusion: This case highlights the rarity and aggressive nature of PBA with bone metastasis. It emphasizes the importance of early detection, comprehensive treatment, and long-term surveillance in managing this challenging disease. Further research is needed to understand the underlying mechanisms and develop effective therapeutic strategies for PBA with bone metastasis.
Co-Authors A, Aditiyono A.W., Gatot Nyarumenteng Aaron Tigor Sihombing Abdul Hadi Hassan Ahmad Agil Ahmad Ramdan Andi Kurniadi, Andi Anita Permatasari Bashari, Muhammad Hasan Bethy S Hernowo Bethy S Hernowo, Bethy Betthy S Hernowo, Betthy S Betthy S. Hernowo Betthy S. S. Hernowo Betty Marlina Birgitta M Dewayani Dandy Tanuwidjaja Darmadji Ismono Darmadji Ismono, Darmadji Deassy Ariefiany Desy Anggraini Desy Anggraini Dewayani, Birgitta Maria Dodi Suardi fachri, Dliyauddin Gatot Nyarumenteng Adhipurnawan Winarno Gita Tiara Dewi Nasution Gunasegaran, Kirtana Handayani, Astri Harsono, Ali Budi Hermin Aminah Usman Husain, Okky I Made Jatiluhur Indra Jaya Irawan, M.Naseh Sajadi Budi Kartika Hapsari Kemala Isnainiasih Mantilidewi Kiki A. Rizki Kirtana Gunasegaran Lindayanti Tanzil M.Naseh Sajadi Budi Irawan Mantilidewi, Kemala I. Misuari Sabirin, Muhammad Syah Muhammad Rivai Noor Fitriana, Maya Rindra Rizqyahya Retossa Rizki Diposarosa Salima, Siti Sari , Rupita Siwendro, Afrisya Bimo Sri Rejeki, Henny Sri Suryanti Sunardi, Mas Adi Suryajaya, Bernard Santoso Suwandi Sugandi Yoyos Dias Ismiarto