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All Journal Jambi Medical Journal : Jurnal Kedokteran dan Kesehatan Majalah Kedokteran Bandung Althea Medical Journal Indonesian Journal of Urology Majalah Patologi Indonesia Bioscientia Medicina : Journal of Biomedicine and Translational Research Jurnal Ilmu Bedah Indonesia Bioscientia Medicina : Journal of Biomedicine and Translational Research Jurnal Locus Penelitian dan Pengabdian Eduvest - Journal of Universal Studies
Anglita Yantisetiasti
Department Of Anatomical Pathology, Faculty Of Medicine/Padjadjaran University, Hasan Sadikin Hospital, Bandung.
Aerospace Engineering Automotive Engineering Biochemistry, Genetics & Molecular Biology Computer Science & IT Decision Sciences, Operations Research & Management Electrical & Electronics Engineering Health Professions Immunology & microbiology Mathematics Medicine & Pharmacology Neuroscience Public Health Social Sciences

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Karakteristik Klinikopatologi Adenokarsinoma Prostat di Rumah Sakit Hasan Sadikin dari Tahun 2016-2023 Farera, Farah; Yantisetiasti, Anglita; Agustina, Hasrayati
Majalah Patologi Indonesia Vol. 35 No. 1 (2026): MPI
Publisher : Perhimpunan Dokter Spesialis Patologi Anatomik Indonesia (PDSPA)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55816/mpi.v35i1.657

Abstract

Background Prostate adenocarcinoma (PA) ranks as the fifth most prevalent malignancy in men and the fifth leading cause of death in Indonesia. The growing number of elderly population and increased use of Prostate Specific Antigen (PSA) testing have led to a threefold rise in Prostate Carcinoma (PC) incidence in recent years. This study aims to profile the clinicopathological characteristics of PA cases at Hasan Sadikin General Hospital (RSHS) in Bandung during the period 2016-2023.   Methods We conducted a descriptive, cross-sectional study at RSHS in Bandung, utilizing medical records for data collection. Inclusion criteria comprised all histopathologically diagnosed PA cases between 2016 and 2023, with exclusion criteria pertaining to patients with incomplete medical records.   Results Our study revealed an average patient age of 72±9.0 year old. The most prevalent age group was those aged 70-79 years old (n=73, 38.8%). The mean PSA level among patients was 256±375.5 ng/ml). The majority of patients were diagnosed at stage IV (n=128, 68.1%). Biopsy was the most frequently used specimen collection method (n=154, 81.9%). Most samples exhibited a Gleason Score of 9 (n=65, 34.6%), belonged to Grade Group 5 (n=84, 44.7%), and had a poorly differentiated histopathological grade (n=132, 70.2%). Approximately 68.1% of patients presented with metastatic disease, with bone metastases being the most common (n=55,70,5 %).   Conclusion PA typically manifests in older individuals, frequently manifesting in 70-79 age group with less favorable histopathological features.
Co-Authors Aaron Tigor Sihombing Abdul Hadi Hassan Ahmad Agil Ahmad Ramdan Anita Permatasari Bashari, Muhammad Hasan Bethy S Hernowo Bethy S Hernowo, Bethy Betthy S Hernowo, Betthy S Betthy S. Hernowo Betthy S. S. Hernowo Betty Marlina Birgitta M Dewayani Dandy Tanuwidjaja Darmadji Ismono Darmadji Ismono, Darmadji Deassy Ariefiany Desy Anggraini Desy Anggraini Dewayani, Birgitta Maria fachri, Dliyauddin Farera, Farah Gatot Nyarumenteng Adhipurnawan Winarno Gita Tiara Dewi Nasution Gunasegaran, Kirtana Handayani, Astri Hasrayati Agustina Hermin Aminah Usman Husain, Okky I Made Jatiluhur Indra Jaya Irawan, M.Naseh Sajadi Budi Kiki A. Rizki Kirtana Gunasegaran Lindayanti Tanzil M.Naseh Sajadi Budi Irawan Mantilidewi, Kemala I. Misuari Sabirin, Muhammad Syah Muhammad Rivai Noor Fitriana, Maya Rindra Rizqyahya Retossa Rizki Diposarosa Sari , Rupita Siwendro, Afrisya Bimo Sri Rejeki, Henny Sri Suryanti Sunardi, Mas Adi Suryajaya, Bernard Santoso Suwandi Sugandi Yoyos Dias Ismiarto