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All Journal BALI MEDICAL JOURNAL (BMJ) Medicina E-Jurnal Medika Udayana E-Journal Obstetric & Gynecology Udayana Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia) ISM (Intisari Sains Medis) : Jurnal Kedokteran Indonesian Journal of Perinatology Journal of Global Pharma Technology
Tjokorda Gde Agung Suwardewa
Departemen Obstetri Dan Ginekologi, Fakultas Kedokteran, Universitas Udayana, RSUP Prof. Dr. I.G.N.G. Ngoerah, Bali, Indonesia
Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Nursing Public Health

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Karakteristik Pasien Kanker Serviks yang Menjalani Radikal Histerektomi dan Limfadenektomi Pelvik Bilateral di RSUP Sanglah Tahun 2018-2019 Kirana, Ni Wayan Prabasiwi; Mahendra, I Nyoman Bayu; Suwardewa, Tjokorda Gde Agung; Winata, I Gde Sastra
E-Jurnal Medika Udayana Vol 12 No 1 (2023): E-Jurnal Medika Udayana
Publisher : Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/MU.2023.V12.i01.P16

Abstract

Cervical cancer is an over or uncontrolled cell growth in the cervix, mainly caused by infection with HPV types 16 and 18. Some prognostic and predictive factors already established to determine the future therapeutic outcomes. Common treatments for early stage cervical cancer are radical hysterectomy and pelvic lymphadenectomy. This study aims to know the characteristic description of cervical cancer patients who had undergone radical hysterectomy and bilateral pelvic lymphadenectomy in Sanglah Hospital from 2018-2019. Samples were chosen from a list of inclusion and exclusion criteria. Data analysis was conducted using the software SPSS ver. 26 to obtain the characteristics of the cervical cancer case that had radical hysterectomy and bilateral pelvic lymphadenectomy based on age, parity, tumor size, clinical stage, histopathological profile which includes histopathological type, degree of differentiation, LVSI, incision margin, parametrial invasion, and pelvic lymph node metastasis. Result shows that cervical cancer patients that had radical hysterectomy and bilateral pelvic lymphadenectomy in Sanglah Hospital, Denpasar, Bali from 2018-2019 are 50.9% from the age group 46-55 years old, 69.8% with multiparity (2-4 children), 69.8% were found with tumor <4cm, and 35.8% were found with stage IIB cancer. The most common histopathological type was squamous cell carcinoma (47.2%). Vaginal incision margins and parametrial invasion were generally negative, 73.6% and 86.8%. Pelvic lymph node metastases were also mostly negative (77.4%). Most of the data on the degree of differentiation and LVSI were not listed (92.6% and 50.9%). There was no significant relationship between age, parity, tumor size, clinical stage, histopathological type, and pelvic lymph node metastases.
ANGKA KELANGSUNGAN HIDUP PASIEN KANKER SERVIKS DI RUMAH SAKIT UMUM PUSAT PROF. DR. I.G.N.G. NGOERAH Mahastya, I Wayan Cahya; Budiana, I Nyoman Gede; Mulyana, Ryan Saktika; Suwardewa, Tjokorda Gde Agung; Wijaya Surya, I Gede Ngurah Harry
E-Jurnal Medika Udayana Vol 13 No 8 (2024): E-Jurnal Medika Udayana
Publisher : Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/MU.2024.V13.i08.P17

Abstract

ABSTRACT Cervical cancer is a type of cancer that develops in the cervix as a result of an infection with high-risk HPV. Cervical cancer patients have varying survival rates. This will be influenced by the patient's prognostic factors such as age, histopathological type, metastases, stage, tumor size, and treatment modalities. This research employs an analytical observational approach and utilizes a retrospective cohort research design. Survival rates will be measured using Kaplan Meier and log-rank based on prognostic factors. The research was carried out at RSUP Prof. Dr. I.G.N.G. Ngoerah, utilizing data from cervical cancer patients in the year 2021. The sample in this study was 245 samples. From 245 samples, 55 patients (22.4%) experienced events (died), 32 patients (13.1%) were uncensored (alive), and 158 patients (64.5%) were censored. The highest one-year survival rate based on prognostic factors was patients with age <40 years (78.8%), histopathological type of SCC (78.1%), no metastases (78.2%), patients with stage I (81%), tumor size < 2 cm (82.9%), and treatment modalities of chemotherapy, radiotherapy, and hysterectomy (90%). The results of the analysis based on the log rank test which reports only the incidence of metastasis factors show significant results on the one-year survival of cervical cancer patients. The overall one-year survival rate for cervical cancer patients is 77.6%. To determine the survival rate for cervical cancer patients over three and five years, further research is required. Keywords: Cervical cancer, HPV, Kaplan-Meier, Log rank, and Survival rate.
Co-Authors Agrifa Eko Albert Sembiring Alfonso Anggriawan Anak Agung Gede Putra Wiradnyana Anak Agung Ngurah Anantasika Anom Suardika Daniel Hadinata Susanto Endang Sri Widiyanti Evert Solomon Pangkahila Heni Sunyoto I Gde Sastra Winata I Gede Putu Surya I Gusti Kamasan Arijana I Gusti Putu Mayun Mayura I Ketut Surya Negara I Ketut Suwiyoga I Nyoman Gede Budiana I Nyoman Hariyasa Sanjaya I NYOMAN MANTIK ASTAWA I Wayan Artana Putra I Wayan Megadhana I Wayan Putu Sutirta Yasa IB Gde Udyoga Manuaba, IB Gde Udyoga Ida Bagus Putra Adnyana Jaqueline Sudiman Johannes Hartono Kirana, Ni Wayan Prabasiwi Komang W Budiartha Made Bagus Dwi Aryana Made Suyasa Jaya Mahastya, I Wayan Cahya Ni Putu Yoni Prastini Kaesasih Nyoman Bayu Mahendra Piere Emanuel Yoltuwu Ryan Saktika Mulyana Stella Kawilarang Stella Kawilarang, Stella Sugianto Sugianto Wijaya Surya, I Gede Ngurah Harry William Alexander Setiawan