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Penentuan Nilai Sun Protection Factor (SPF) Nanoemulgel Ekstrak Daun Keji Beling dan Kelor Anindita, Reza Anindita; Uzia Beandrade, Maya; Kurnia Putri, Intan; Dwi Nathalia, Dede
JURNAL BIOSHELL Vol 12 No 2 (2023): Oktober
Publisher : Universitas Islam Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56013/bio.v12i2.2380

Abstract

The incidence of skin cancer was found to be 5.9% -7.8% spread across various hospitals or the third position for most cancers after cervical and breast cancer. One solution to prevent skin cancer is the use of sunscreen or sunscreen. The purpose of this study was to determine the SPF value of nanoemulgel ethanol extract of keji beling and kelor leaves. This type of research is quantitative. The samples used were keji beling and kelor leaf extracts. The extraction method is maceration with 96% ethanol solvent. Testing the SPF value using the spectrophotometric method with a wavelength of 290-320 nm with an increase of 5 nm intervals. The results of this study showed that the best nanoemulgel value was found in formula 1 (F1) 5% of 42.17. The SPF value with a concentration of 3% is 12.19 (maximum protection category), 4% is 15.46 (ultra category), and 5% is 11.33 (maximum category). The conclusion from the study of nanoemulgel extracts of keji beling and kelor leaves has the potential to be used as a sunscreen preparation.
Antibacterial Bioactivity Test of Bilimbi Fruit Ethanol Extract (Averrhoa bilimbi Linn). Against Propionibacterium acnes, Staphylococcus epidermidis and Staphylococcus aureus Anindita, Reza; Nathalia, Dede Dwi; Perwitasari, Melania; Putri, Intan Kurnia; Beandrade, Maya Uzia; Harahap, Nofria Rizki Amalia
Biology, Medicine, & Natural Product Chemistry Vol 13, No 1 (2024)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14421/biomedich.2024.131.173-182

Abstract

One of the causes of acnes is the bacteria Propionibacterium acnes, Staphylococcus epidermidis, and Staphylococcus aureus. An alternative solution to this problem is to develop natural medicines from plants, one of which is the star fruit (Averrhoa bilimbi Linn). The purpose of this study was to test the bioactivity of star fruit against the growth of P. acnes, S. epidermidis, and S. aureus. This research method used an experimental research design with the treatment of A. bilimbi fruit ethanol extract concentrations of 50%, 60%, 70%, 80%, and 90%, chloramphenicol antibiotics as control (+), and sterile distilled water as control (-). All treatments were given to P. acnes, S. epidermidis, and S. aureus bacteria using the Kirby Baeur (disc diffusion) method. The results of this study were the effectiveness of the bioactivity compound of the ethanolic extract of A. bilimbi fruit seen on P. acnes and S. epidermidis bacteria with concentrations of 70%, 80%, and 90%. Thus, it can be concluded that A. bilimbi fruit has the potential to be developed as a natural medicine for acne caused by P. acnes and S. epidermidis.
Density of House Dust Mites (HDM) Dermathopagoides sp. In Jatimulya Village South Tambun District Bekasi City Reza Anindita; Salma Lailatul Amwia; Maulin Inggraini; Dede Dwi Nathalia
Jurnal Medis Islam Internasional Vol 3 No 2 (2022): June
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/iimj.v3i2.3015

Abstract

Background: House Dust Mites (HDM) are arthropods that trigger allergies such as asthma and rhinitis. The percentage of these animals as the cause of asthma according to WHO data (2013) is around 50% -80%. Objective: The purpose of this study was to obtain new information about the density of HDM in the city of Bekasi as well as to complement the existing data so that it can be used as a reference in formulating an allergy prevention program caused by HDM. Methods:This  study  was  designedwith  a  quasi-experimental  study  research  method using a comparative pre-test post-test non-equivalent control group design.The sample in this study was divided into two groups, namely one control group and one treatment group  from  the  sample  selected  by  purposive  sampling.  The population studied were students of the Hidayatullah Islamic Boarding School inSurabaya. Result: This type of research is quantitative descriptive with a cross-sectional research design. The sample in this study were 9 houses of residents of the village of Jati Bulak, RT 001/ RW 003, Jatimulya Village, Tambun Selatan District. The location points for dust sampling for each house are mattresses, carpets and floors. The working procedure of this research includes the pre-analytic stage in the form of preparation of tools and materials, the analytical stage in the form of HDM examination with the sedimentation method, the post-analytic stage in the form of confirmation of HDM identification. Conclusion:From research result that has been done, it can be concluded that the HDM figures in 9 houses of Jati Bulak villagers RT 001/ RW 003 Jatimulya Village, Tambun Selatan District are in the low category.
Monitoring Pediculosis Capitis in Students At Al-Muhajirin Islamic Boarding School, Cikarang Pusat, West Java, Indonesia Anindita, Reza; Wahyu, Ega Nuraini; Perwitasari, Melania; Nathalia, Dede Dwi; Beandrade, Maya Uzia; Harahap, Nofria Rizki Amalia
Jurnal Medis Islam Internasional Vol 5 No 2 (2024)
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/iimj.v5i2.5783

Abstract

Introduction : Pediculosis capitis is a scalp hair disorder caused by an infestation of the lice of Pediculus humanus capitis. The spread of this disease is dominant in Islamic boarding school students. This disease besides causing itching and lesions on the scalp also causes loss of concentration and enjoyment of learning in children. The objective of this study was to determine the percentage of female students infested with P. humanus capitis. Methods : The design of this research is cross-sectional. The sample for this study was 41 female students of grade 7 at AL-Muhajirin Islamic Boarding School, Central Cikarang, West Java. Examination of  P. humanus capitis on all female students was carried out using the serit method. The P. humanus capitis lice found were then collected and preserved preparations were made for microscopic morphological identification. Results : The results of this study showed that from 41 samples, 36 (87.8%) students were found to be positive for P. humanus capitis. Conclusions : The conclusion from this study is that the percentage of pediculosis capitis in female students is high, so it is necessary to take countermeasures in the form of head lice medication and education about personal hygiene for class 7 female students at Al-Muhajirin Islamic Boarding School, Central Cikarang, West Java
Anti-Bacterial Activity of Etanolic Extract and Essential Oil of Basil (Ocimum sanctum) on Growth Staphylococcus aureus Salmonella thypii and Eschericia coli Perwitasari, Melania; Anindita, Reza; Beandrade, Maya Uzia; Nathalia, Dede Dwi; Hasmar, Wahyu Nuraini; Putri, Intan Kurnia
Jurnal ILMU DASAR Vol 24 No 2 (2023)
Publisher : Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/jid.v24i2.31367

Abstract

Antimicrobial resistance is one of the biggest health problems. Indonesia is a country with a positive high number of E. coli (71%) Extended Spectrum Beta Lactamase (ESBL) in the Asia Pacific. Many studies report that essential oils and extracts from several species of Ocimum have antimicrobial activity against gram-positive and negative bacteria. Antibacterial activity is related to active compounds contained in plants that are also affected by the place of growth, harvesting and post-harvesting. Research related to the activity of basil (Ocimum sanctum) that already exists does not provide complete and comprehensive data related to where to grow, harvest and post-harvest basil leaves. Basil leaves that have been set parameters for growth, harvest and post-harvest processes are extracted using maceration method with 70% etanol solvent and distilled to obtain essential oils (EO). Etanolic extract (EE) and EO were tested for their activity against Escherichia coli, Staphylococcus aureus and Salmonella thypii bacteria. The results showed that the basil leaves obtained from Margahayu sub-district, East Bekasi, had a dry simplicia yield of 12.8% ± 1.5, yield of EE 16.9% ± 1.6, EO content of 0.56%. The etanolic extract of basil leaves contains alkaloids, saponins, tannins, phenolics, flavonoids, glycosides, triterpenoids and steroids. The conclusion from the results of this study is the etanol extract and essential oils of basil leaves can inhibit the growth of bacteria, both basile leaves. The inhibition zone diameter is higher in gram positive bacteria (S. aureus) than gram negative bacteria (S. thypii and E. coli).
EPIDEMIOLOGY OF PITYRIASIS VERSICOLOR IN ELEMENTARY SCHOOL CHILDREN IN THE BANTAR GEBANG, BEKASI Anindita, Reza; Eka Wahyu Wulandari; Maulin Inggraini; Melania Perwitasari; Maya Uzia Beandrade; Dede Dwi Nathalia; Intan Kurnia Putri
Muhammadiyah International Public Health and Medicine Proceeding Vol. 3 No. 1 (2023): PROCEEDING MUHAMMADIYAH INTERNATIONAL PUBLIC HEALTH AND MEDICINE CONFERENCE - T
Publisher : Fakultas Kesehatan Masyarakat Universitas Muhammadiyah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61811/miphmp.v3i1.449

Abstract

Pityriasis versicolor (PV) is a disease caused by a superficial fungus, namely Malassezia furfur. This disease is chronic with skin appearance that has characteristics in the form of well-defined skin lesions and white (hypopigmentation) and pink to brownish (hyperpigmentation). PV disease causes itching and a psychological impact in the form of a decrease in self-confidence. The purpose of this study was to determine the percentage of PV incidence in elementary school children at the Garbage Disposal Site, Bantar gebang, Bekasi, West Java. This type of research is quantitative and descriptive with a cross-sectional design. The research sample consisted of 87 elementary school students in grades 1 and 2 who were selected based on inclusion criteria, namely the presence of hypopigmented and hyperpigmented lesions. The examination was carried out microscopically with the solatip method using 10% KOH. Data analysis was performed by using descriptive statistical tests. The results of this study showed that there were 35 (40%) students who were positively infected with PV, which was confirmed by the presence of spores and hyphae of the fungus M. furfur. The age most affected by PV is 7 years old, with a percentage of 17 (49%) students, while the percentage of the sex most affected by PV is male, with as many as 23 (53%) students. The study concludes that the prevalence of children in grades 1 and 2 at Yayasan Dinamika Indonesia Elementary School around the Bantargebang landfill, Bekasi, West Java, is in the middle category. The factors that influence the incidence of PV in this study are outdoor activities, which cause the facial area to sweat easily, and lack of personal hygiene.
Simulation of Betel Leaf Extraction as a Provision of Entrepreneurship Knowledge for Students Regarding the Preparation of Raw Materials for Pharmaceutical Products Reza Anindita; Dede Dwi Nathalia; Intan Kurnia Putri; Melania Perwitasari; Maya Uzia Beandrade
Bubungan Tinggi: Jurnal Pengabdian Masyarakat Vol 6, No 4 (2024)
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/btjpm.v6i4.11875

Abstract

Referring to the need to provide materials and skills regarding the preparation and extraction of natural ingredients with medicinal potential to vocational pharmacy students, it is necessary to carry out integrated school Community Service (Pengabdian Kepada Masyrakat or PKM) activities. This Community Service aims to assess the level of knowledge and skills regarding the preparation and extraction of betel leaf simplicia before being formulated into various pharmaceutical products. This Community Service activity was carried out using the method of simulation and demonstration on the preparation and extraction of green betel leaf simplicia. The results of the activities were then evaluated using the pre and post-test methods to measure participants' understanding of the preparation and extraction of betel leaves. The participants of this Community Service were from Daya Utama Vocational High School, consisting of 26 students accompanied by three supervising teachers. Before being given materials and skills for preparing and extracting natural ingredients, the average score of students' knowledge level was 52.5. After the provision of materials and skills, it increased to 69.3. The conclusion was that the student's knowledge level increased by 16.73, with the t-test results showing a significant difference before and after the provision of materials and skills.
Community Knowledge about Medicinal Plants in Samudra Jaya and Pahlawan Setia Villages, North Bekasi Anindita, Reza; Haediningrum, Syahla; Beandrade, Maya Uzia; Putri, Intan Kurnia; Nathalia, Dede Dwi; Perwitasari, Melania; Harahap, Nofria Rizki Amalia; Rahmadi, Chandra
Journal of Tropical Ethnobiology Vol. 7 No. 1 (2024): January 2024
Publisher : The Ethnobiological Society of Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The purpose of this study was to describe the knowledge and use of medicinal plants by the people of Samudra Jaya and Pahlawan Setia Villages, Tarumajaya Sub-district, North Bekasi. The research design is an exploratory survey and observation. The sample numbered 119 people, consisting of 69 people representing Pahlawan Setia Village and 50 people representing Samudra Jaya Village. The sampling technique used purposive random sampling. Variables in this study include the value of community knowledge about medicinal plants, the value of community knowledge about the use of medicinal plants, the organs of plants that are often used, the percentage of how to use medicinal plants, and the families and species of plants used as medicine. Data analysis was carried out descriptively. The results showed that the value of community knowledge about medicinal plants was 354 (classified as good), the value of community knowledge regarding the use of medicinal plants was 300.4 (classified as good), the organs of plants that were often used as medicine were leaves (95%), the percentage of how to use medicinal plants are more dominant by boiling (91%), there are 19 families with 22 species of plants used as medicine. The family includes Zingiberaceae, Polygonaceae, Liliaceae, Acanthaceae, Oxalidaceae, Talinaceae, Crassulaceae, Rubiaceae, Lamiaceae, Piperaceae, Basellaceae, Euphorbiaceae, Solanaceae, Caricaceae, Menispermaceae, Asparagaceae, Zingiberaceae, Myrtaceae, Rutaceae, Leguminosae, and Moraceae, with plant species: kunyit (Curcuma domestica), jambu biji (Psidium guajava), sirih hijau (Piper betle), mengkudu (Morinda citrifolia), lidah buaya (Aloe vera), brotowali (Tinospora crispa), sambiloto (Andrographis paniculata), saga (Abrus precatorius), jahe (Zingiber officinale), belimbing wuluh (Averrhoa bilimbi), cocor bebek (Kalanchoe pinnata), ciplukan (Physalis peruviana), jeruk nipis (Citrus aurantiifolia), jarak pagar (Jatropa curcas), kumis kucing (Orthosiphon aristatus), gondola (Basella rubhalin), pepaya (Carica papaya), ginseng jawa (Talinum paniculatum), telang (Clitoria ternatea), getih-getihan (Rivina humilis), tin (Ficus carica), and suji (Dracaena angustifolia). The study concludes that the results of survey scores regarding the knowledge and use of medicinal plants by the people of Samudra Jaya and Pahlawan Setia Villages are classified as good. The species of medicinal plants that are most widely used are the Zingiberaceae family, with local names of plant species, namely jahe and kunyit. Both plants are used by boiling to relieve menstrual pain and treat bloating and colds.
ACCURACY OF THE USE OF ANTITUBERCULOSIS DRUGS IN PATIENTS WITH PULMONARY TUBERCULOSIS COMORBID WITH TYPE 2 DIABETES MELITUS IN HOSPITAL X BEKASI CITY FOR THE PERIOD 2019-2022: ACCURACY OF THE USE OF ANTITUBERCULOSIS DRUGS IN PATIENTS WITH PULMONARY TUBERCULOSIS COMORBID WITH TYPE 2 DIABETES MELITUS IN HOSPITAL X BEKASI CITY FOR THE PERIOD 2019-2022 rachmita arianti, Anisa; Dzakiya, Meisya Putri; Harahap, Nofria Rizki Amalia; Nathalia, Dede Dwi
Jurnal Mitra Kesehatan Vol. 7 No. 1 (2024): Jurnal Mitra Kesehatan
Publisher : STIKes Mitra Keluarga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47522/jmk.v7i1.373

Abstract

Introduction: Pulmonary tuberculosis is a chronic infection caused by the bacterium Mycobacterium tuberculosis. The disease can lead to severe complications, including diabetes, which increases the risk of death. In addition, the prevalence of TB-DM in Indonesia reaches 14.8%. Objective: This study was to evaluate the use of antituberculosis drugs in patients with pulmonary TB comorbid with diabetes mellitus using the right indication, right dose, and right drug indicators. Methods: The research design used was observational with a retrospective approach. This study used independent variables including age, gender, treatment profile, stage of treatment, correct drug, correct dose and correct indication. The sampling technique used was consecutive sampling. The sample of this study consisted of 62 outpatients who were analyzeddescriptively quantitatively using Microsoft Excel. Results: This study shows that the number of male (65%) and female (35%) patients with the majority age 46-55 years (45%). Lung TB drug use therapy is dominant OAT Kombipak (69.4%) and KDT (30.6%). Evaluation of drug use showed the level of indication accuracy of 100%, the right dose of 83.9%, and the right drug of 93.5%. Conclusion: Based on compliance with the "National Guidelines for TB Control" issued by the Ministry of Health of the Republic of Indonesia in 2016, the treatment provided to outpatient TB patients with DM comorbidity at Hospital X in Bekasi Cityfrom 2019 to 2022 showed a 100% accuracy rate for indications (62 patients), 83.9% accuracy rate for dosages (52 patients), and 93.5% accuracy rate for drug selection (58 patients).
Botany, Pharmacognosy, and Phytochemical Study of Gymnanthemum amygdalina (Delile) Sch.Bip. Leaves from Bandung, West Java, Indonesia Anindita, Reza; Tahapary, Manuela Esterlita; Nathalia, Dede Dwi; Putri, Intan Kurnia; Beandrade, Maya Uzia
RUMPHIUS Vol 7 No 2 (2025): RUMPHIUS Pattimura Biological Journal
Publisher : Universitas Pattimura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30598/rumphiusv7i2p138-147

Abstract

Gymnanthemum amygdalina (Delile) Sch.Bip. possesses antioxidant, antibacterial, anticholesterol, anticancer, and antidiabetic properties. This study aimed to determine the morphology of leaves, stems, flowers, and roots, as well as the microscopic powder characteristics, phytochemical profile, and Thin Layer Chromatography (TLC) pattern of G. amygdalina leaves. The samples were collected from Bandung City, West Java, Indonesia. Methods included morphological examination, microscopic powder analysis, phytochemical screening, and TLC. The morphological characterization of G. amygdalina showed that the leaves measured 10–22 cm in length and 2–8 cm in width, with an oblong shape, acuminate tips, acute bases, pinnate venation, serrated margins, rough surfaces, woody stems, and a taproot system. Microscopic examination revealed fragments of trichomes. Phytochemical screening indicated the presence of alkaloids, flavonoids, saponins, tannins, and terpenoids/steroids. TLC analysis showed five red spots with an average Rf value ranging from 0.06 to 0.58. In conclusion, the morphological characteristics of G. amygdalina leaves were identified, microscopic analysis revealed trichome fragments, and phytochemical screening confirmed the presence of secondary metabolites. TLC analysis yielded Rf values between 0.06 and 0.58.