Article Per Year (5 Year)
p-Index From 2020 - 2025
4.801
P-Index
This Author published in this journals
All Journal Jurnal Penelitian Saintek Bioma : Berkala Ilmiah Biologi AL KAUNIYAH Biota: Jurnal Ilmiah Ilmu-Ilmu Hayati Pharmaciana: Jurnal Kefarmasian Eksergi: Chemical Engineering Journal Journal of Natural Sciences and Mathematics Research Jurnal Kimia Riset Majalah Ilmiah Biologi BIOSFERA: A Scientific Journal Biosaintifika: Journal of Biology & Biology Education Buletin Anatomi dan Fisiologi (Bulletin of Anatomy and Physiology) JKPK (Jurnal Kimia dan Pendidikan Kimia) International Journal of Active Learning Indigenous Biologi Bioed : Jurnal Pendidikan Biologi BIOCHEPHY: Journal of Science Education Jurnal Ilmiah Sains Gunung Djati Conference Series Engagement: Jurnal Pengabdian Kepada Masyarakat Jurnal Pengabdian Kepada Masyarakat
Elizabeth Betty Elok Kristiani
Universitas Kristen Satya Wacana
Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Energy Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Physics Public Health Social Sciences Other

Published : 36 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 36 Documents
Search

 1   2   3   4 
Biokeramik Hidroksiapatit (HAp) Berbahan Dasar Cangkang Tiram Anodonta nuttaliana dari Danau Poso Agung Rimayanto Gintu; Elizabeth Betty Elok Kristiani; Yohanes Martono
Eksergi Vol 17, No 2 (2020)
Publisher : Prodi Teknik Kimia, Fakultas Teknologi Industri, UPN "Veteran" Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31315/e.v17i2.3758

Abstract

Bioceramic Hydroxyapatite (HAp) was a derivated chemical synthetic compound from calcium phosphate commonly used to care the damage of hard tissues. Bioceramic Hydroxyapatite can synthetized from the compounds which rich with calcium contains. In this study threated the synthesis and physicochemical characterization to the HAp made from Anodonta nuttaliana clam shells obtained from Poso lake. From the characterization of the sample A. nuttaliana shells obtained the water contains 0,50±0,00%; ash contains 0,9827±0,0022g/g; potasium 0,00135±0,0002g/g; calcium 0,0165±0,0034g/g; phosphate 0,1920±0,0424g/g and the ratio of Ca/P 1,9389±0,3039%. The synthesis of HAp by base precipitation method showed the yield of synthesis 95,4320±0,7085% with the characteristic of the HAp showed that the potassium contains 0,0005±0,00004g/g; calcium 0,95476±0,0012g/g; phosphate 0,528±0,0075; ratio of Ca/P 1,0307±0,0932%; porosity 73,9598±1,1320%; swelling ability 9,6067±2,5365%; and biodegradability 8,8206±0,2176%. From the overall results concluded that the A. nuttaliana clam shells was very potential to became a source of Bioceramic Hydroxyapatite (HAp).
The antioxidant activity of Zingiber officinale, Hibiscus sabdariffa, and Caesalpinia sappan combination Ari Hasna Widyapuspa; Elizabeth Betty Elok Kristiani; Yohanes Martono
Pharmaciana Vol 12, No 1 (2022): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (584.317 KB) | DOI: 10.12928/pharmaciana.v12i1.20903

Abstract

Medicinal plants have been used in traditional treatment since a long time ago by local people in Indonesia. Nowadays, the trend in the consumption of medicinal plants, especially herbal drinks, is increasing. Zingiber officinale, Hibiscus sabdariffa, and Caesalpinia sappan are their main materials of medicinal plants. They were chosen because of their high antioxidant contents. Nevertheless, there is no scientific research on the antioxidant activity of the combination of the three extracts. Therefore, the purpose of this study was to determine the total flavonoid contents and antioxidant activity, as well as to compare the antioxidant enhancement pattern of the combination. Samples were extracted by successive maceration with hexane and ethyl acetate as solvents. Total flavonoids contents were determined through colorimetric analysis and antioxidant activity was determined based on the DPPH method with the IC50 value as a parameter. Total flavonoids of ethyl acetate extract from Z. officinale, H. sabdariffa, and C. sappan were 30.28±0.04; 24.81±0.03; and 24.01±0.04 mg QE/ gram extract, and the IC50 value were 51.36±0.05; 83.37±0.06; and 35±0.04 ppm. Total flavonoid contents of their combination were 22.48±0.05 (0:1:1); 23.88±0.05 (1:1:1); 23.68±0.05 (1:4:1); 22.81±0.05; 28.81±0.04 (4:1:1); 27.55±0.03 (1:1:0); 24.41±0.04 mg QE/ gram extract (1:0:1). Antioxidant activities obtained from the combination were 57.50±0.05 (0:1:1); 52.25±0.06 (1:1:1); 71.50±0.06 (1:4:1); 45.74±0.05 (1:1:4); 54.36±0.05 (4:1:1); 68.97±0.06 (1:1:0); 40.52±0.05 ppm (1:0:1). The strongest antioxidant activity was C. sappan. 
EFFECT OF DIFFERENT METHODS OF COMPONENTS SOURCE OF OUTLINE OF NEW PLANT OIL (Artemisia vulgaris L) AND AN EFFECT OF ANTIBOYTE Hartati Sulastri; Elizabeth Betty Elok; Lilik Linawati
Jurnal Penelitian Saintek Vol 19, No 2: Oktober 2014
Publisher : Institute of Research and Community Services, Universitas Negeri Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (336.194 KB) | DOI: 10.21831/jps.v19i2.3506

Abstract

Mugwort (Artemisia vulgaris L) from Tawangmangu Central Java was extracted by water distillation, water steam and steam distillation. Essential oil Mugwort were analized by GCMS. The result showed that the chemical composition of mugwort essential oil from water distillation were composed of 36 compounds, water-steam distillation showed 34 compounds whereas steam distillation showed 29 compounds. Nevertheless three distillation methods gave similar 6 dominant compounds in different concentration. Six dominant compounds were 3,5-dimethyl-4-ethylidene-cyclohex-2-ene-1-one, filifolone, germacrene-D, gamma-caryophyllene, eucarvone and 1,8-cineol, the amounts of each of them was more than 3%. Bioautography test showed that mugwort essential oil have a good antibacterial effect especially to E.coli bacteria
Karakterisasi Pasta Gigi Berbahan Abrasif Hidroksiapatit (HAp) Agung Rimayanto Gintu; Elizabeth Betty Elok Kristian; Yohanes Martono
Jurnal Kimia Riset Vol. 5 No. 2 (2020): Desember
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jkr.v5i2.22503

Abstract

Tootpaste was a product for dental care to clean, beautify and replace the minerals decay from the dent surface. To prevent the damage of the mineral layers on the surface, added the remineralitation compounds in the formula of the toothpaste. The remineralitation agents commonly add was CaCO3 and CaPO4, during the technological development the calcium compounds added was calcium in nano size like Hydroxyapatite (HAp). In this study produced the contains abrasive HAp and CaCO3 with the mix ratio  CaCO3, 50:50 (HAp:CaCO3) and HAp. The characterization to the toothpaste with CaCO3 abrasive showed the Calcium contains 21,10 ± 0,0577%; dispersibility 936,37 ± 39,42gcm/s; pH 8,3 ± 0,00; and viscosity 25 ± 0,00 P.a. The toothpaste with CaCO3:HAp (50:50) abrasive showed the Calcium contains 27,03 ± 0,0333%; dispersibility 931,93 ± 22,62gcm/s; pH 8,8 ± 0,00; and viscosity 27 ± 0,00 P.a. The toothpaste with HAp abrasive showed the Calcium contains 27,67 ± 0,0882%; dispersibility 987,33 ± 39,50gcm/s; pH 8,9 ± 0,00; and viscosity 27,5 ± 0,00 P.a. The contamination of microbiology did not found in all of the toothpastes along the storage. Based on the entire organoleptic test against the toothpastes, the formula of toothpaste with the mix of CaCO3:HAp was les liked.
The Synthesis and Physicochemical Characterization of Hydroxyapatite (HAp) from Local Duck Egg Shells Agung Rimayanto Gintu; Elizabeth Betty Elok Kristiani; Yohanes Martono
JKPK (Jurnal Kimia dan Pendidikan Kimia) Vol 7, No 1 (2022): JKPK (Jurnal Kimia dan Pendidikan Kimia)
Publisher : Program Studi Pendidikan Kimia FKIP Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/jkpk.v7i1.55429

Abstract

Hydroxyapatite (HAp) Biocheramics was the main component of remineralisation agent to the hard tissues; it is commonly synthesized from compounds rich with calcium. One of the compounds recommended as a HAp source was eggshells. This study aimed to synthesize the HAp from local duck eggshells containing Calcium 0,8631 ± 0,0015g/g and Phosphor 0,3118 ± 0,0016g/g. The synthesis process of HAp by Base Precipitation methods showed rendement 85,06 ± 1,0135%. The Physicochemical characterization to the HAp showed the Calcium contains 0,4760 ± 0,0027g/g; Phosphor 0,0897 ± 0,0023g/g; Porosity 82,0106 ± 0,4484%; Biodegradability 5,3506 ± 0,0295%; and Swelling ability 5,7678 ± 0,1897%. The results concluded that the local duck egg shells were recommended as HAp sources. Based on characterisation results, the HAp made from it was potentially applied as a remineralization agent.
Kadar Flavonoid, Senyawa Biomarker Antikanker pada Tumbuhan Famili Asteraceae dari Daerah Kopeng Kabupaten Semarang Indonesia Elizabeth Betty Elok Kristiani; Sri Kasmiyati
Majalah Ilmiah Biologi BIOSFERA: A Scientific Journal Vol 37, No 1 (2020)
Publisher : Fakultas Biologi | Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (748.245 KB) | DOI: 10.20884/1.mib.2020.37.1.1058

Abstract

The Asteraceae family plants are reported to have various abilities as drugs. Artemisia belongs to the Asteraceae family has been used as a drug for malaria, and recent developments have been studied for its ability as anticancer agents. Cosmos caudatus, a member of the Asteraceae family that believed by many people for its ability to heal cancer. The aims of this study were to determine the content of quercetin, kaempferol, and artemisinin which is an anticancer biomarker compound in A. annua, A. vulgaris Linn., A. chinese Berg ex Poljakov, and Cosmos caudatus Kunth which grow in Kopeng blood, Semarang Regency, Province Central Java. The plant samples were dried and mashed up. The content of biomarker compounds was determined using using High Performance Liquid Chromatography (HPLC). The artemisinin levels in A. annua, A. vulgaris Linn., A. cina Berg Poljakov, and Cosmos caudatus Kunth were 0.2800; 0.3000; 0.1700; and 0.0300% respectively. The kaempferol was detected in the three Artemisia were 0.2987; 0.0013; and 0.0074%. In all four plants, quercetin was only detected in A. annua.
UJI ANTIBAKTERI DAN MODIFIKASI HIDROKSIAPATIT DARI LIMBAH KERABANG TELUR BEBEK (A. platyrhynchos javanica) Agung Rimayanto Gintu; Elizabeth Betty Elok Kristiani; Yohanes Martono
Gunung Djati Conference Series Vol. 18 (2023): Prosiding Seminar Nasional Biologi (SEMABIO) Tahun 2022
Publisher : UIN Sunan Gunung Djati Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (811.121 KB)

Abstract

Hydroxyapatite (HAp) was one of synthetic compounds synthesized from raw materials like eggshells, HAp initiated to applied in toothpaste formulations as active compounds role as abrasives, remineralitation agents and antibacteries against caries. The aim of this study was to measured the antibacterial activity of HAp synthesized from Local Duck (A. platyrhynchos javanica) eggshells against 4 species of caries bacteries: S. mutans, L. acidophyllus, N. asteroides and N. asteroides. The concentration of HAp separated into 3 levels: 100, 500 and 1000ppm, the antibacterial activity of HAp only produced against L. acidophyllus at 1000ppm concentration of HAp, the diameter of inhibitory showed 5,19 ± 0,0203mm, this activity belongs to weak activity then need to modified the HAp to increasing the antibacterial activity. The HAp modificated by Mix and Doped. The strongest antibacterial showed by Silver (Ag) doped, with diameter of inhibitory against 4 caries bacteries sequentaly 17,91 ± 0,1723mm; 23,10 ± 0,0361mm; 19,06 ± 0,0348mm; and 19,12 ± 0,0493mm; those modifications increating the antibacterial from weak to strong and very strong range.
An antioxidant capacity of ethanol and ethyl acetate extracts of areca nut (Pinanga ceasia Blume), a plant endemic to Central Sulawesi Elizabeth B.E Kristiani; Jeanelsin A.P Langgori
Jurnal Ilmiah Sains Volume 23 Nomor 1, April 2023
Publisher : Sam Ratulangi University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/jis.v23i1.46097

Abstract

The purpose of this study to measure the antioxidant ability and content of phenolic and flavonoid compounds in ethanol and ethyl acetate extracts of areca nut (Pinanga ceasia Blume) taken from the Central Sulawesi region. The fruit were divided in the skin, seeds, and flesh. Samples were extracted by maceration using two types of solvents, namely ethanol and ethyl acetate. The parameters of the study were measured spectrophotometrically using specific reagents. The reagents used were DPPH for antioxidant activity test, Folin-Ciocalteu reagent for testing phenolic compound levels, and AlCl3 reagent for flavonoid level testing. The phenolic content of the ethanolic extract of the seeds and fruit flesh was in the range of 3,500 – 4,500 g equivalent of gallic acid/g extract, while the flavonoid content was in the range of 1,700 – 1,800 g equivalent of quercetin/g of extract. This value is much higher than other extracts in the range of 170 – 740 g bioactive equivalent/g extract. The antioxidant ability of the ethanol extract of the seeds and fruit pulp increased with increasing concentration of the extract, while the other extracts were relatively the same at all test concentrations. Keywords: antioxidant; flavonoid; maceration; phenolic; Pinanga ceasea Blume Kapasitas Antioksidan Ekstrak Etanol dan Etil Asetat Buah Pinang (Pinanga ceasia Blume), Tanaman Endemik Sulawesi Tengah ABSTRAK Penelitian ini bertujuan untuk untuk mengukur kemampuan antioksidan dan kadar senyawa fenolik dan flavonoid pada ekstrak etanol dan etil asetat buah pinang (Pinanga ceasia Blume) yang diambil dari daerah Sulawesi Tengah. Buah pinang dipisahkan bagian kulit, biji, dan daging buah. Sampel diekstraksi secara maserasi menggunakan dua jenis pelarut yaitu etanol dan etil asetat. Parameter uji diukur secara spektrofotometri menggunakan reagen spesifik. Reagen yang digunakan yaitu DPPH untuk uji aktivitas antioksidan, reagen Folin-ciocalteu untuk uji kadar senyawa fenolik, dan reagen AlCl3 untuk uji kadar flavonoid. Kadar fenolik ekstrak etanol biji dan daging buah pada kisaran 3.500 – 4.500 µg ekivalen asam galat/g ekstrak sedangkan flavonoid pada kisaran 1.700 – 1.800 µg ekivalen kuersetin/g ekstrak. Nilai tersebut jauh lebih tinggi dibanding ekstrak lain yang ada pada kisaran 170 – 740 µg ekivalen bioaktif/g ekstrak. Kemampuan antioksidan ekstrak etanol biji dan daging buah meningkat seiring meningkatnya konsentrasi ekstrak sedangkan ekstrak lain relative sama pada semua konsentrasi uji. Ekstrak etanol biji dan daging buah Pinanga ceasea Blume memiliki kadar flavonoid dan flavonoid lebih dari dari kulit buah. Kemampuan antioksidan ekstrak etanol biji dan daging buah Pinanga ceasea Blume lebih tinggi dibandingkan ekstrak lain. Kata kunci: Antioksidan; fenolik; flavonoid; maserasi; Pinanga ceasea Blume
The Antioxidant Content and Activity of Various Plant Organs of Kitolod (Isotoma longiflora) Grahita Rezhi Egarani; Sri Kasmiyati; Elizabeth Betty Elok Kristiani
Biosaintifika: Journal of Biology & Biology Education Vol 12, No 3 (2020): December 2020
Publisher : Department of Biology, Faculty of Mathematics and Sciences, Semarang State University . Ro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/biosaintifika.v12i3.23888

Abstract

Antioxidants play a crucial role in human health owing to their ability to neutralize oxidative reactions. Kitolod (Isotomalongiflora) is one of the medicinal plants that can be used as a source of antioxidant. The aim of study wasto compare the content of antioxidant compounds (flavonoids, phenolics, chlorophylls, carotenoids, and ascorbic acid) in various organs of the kitolod plant. The plant organs studied includingroots, stems, leaves, flowers, and fruits. The extraction of each plant organ wasconducted by maceration technique using ethanol as a solvent at the room temperature for 48 hours. The analysis of total flavonoids, phenolics, and ascorbic acid was performed by colorimetry method using AlCl3, Folin, and sulfosalicyclic acid reagent respectively, while chlorophylls and carotenoids was determined by direct colorimetry method with methanol as a solvent. The antioxidant activity of various plant organs of kitolod was analyzed using the DPPH method. The highest total flavonoid, phenolic, chlorophyll, and carotenoid compounds werefound in leaves, respectively by 10.48, 1.46, 7.25, and 56.98 ppm. The highest ascorbic acid content and antioxidant activity were obtained fromfruits.The research findings provide new and important information aboutthe contents and antioxidant activity of the secondary metabolites (flavonoid, phenolic, chlorophyll, carotenoid, and ascorbic acid) in each organ of kitolod plant. The information from the results of this study can be used to increase the medicinal value ofkitolod plants.
Antibacterial Activity and Flavonoids Content of Artemisia cina Berg. ex Poljakov Ethyl Acetate Extracts Sri Kasmiyati; Elizabeth Betty Elok Kristiani; Maria Marina Herawati; Andreas Binar Aji Sukmana
Biosaintifika: Journal of Biology & Biology Education Vol 13, No 1 (2021): April 2021
Publisher : Department of Biology, Faculty of Mathematics and Sciences, Semarang State University . Ro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/biosaintifika.v13i1.27665

Abstract

The medicinal plant-derived bioactive compounds have a potential for many biological activities, including antimicrobial activity. Artemisia cina is a medicinal plant from the Compositae family with the potential of having antitumor, antifungal, and antibacterial activity. This study aimed to determine the antibacterial activity and the flavonoid content of A. Cina’s ethyl acetate extract. Plants samples were extracted by ethyl acetate maceration method. Antibacterial activity was tested against Gram-negative bacteria (Escherichia coli and Pseudomonas aeruginosa) and Gram-positive bacteria (Bacillus subtilis and Staphylococcus aureus) by a disk diffusion method using 25, 50, and 100 mg/l extract concentrations. The flavonoid contents (quercetin and kaempferol) were measured using High-Performance Liquid Chromatography. The extracts of diploid and polyploid A. cina displayed some antibacterial activity, with the Gram-negative bacteria being more resistant than the Gram-positive counterpart. However, no significant difference was observed between the diploid and polyploid extracts. As for the flavonoid content, the highest quercetin content (0.5501 mg/ml) was found in the polyploid A. cina (J), while the highest kaempferol content (0.5818 mg/ml) was observed in the diploid A. cina (KJT). Although A. cina is widely grown in Indonesia, compared to other Artemisia species, A. cina has not been widely studied, especially its antibacterial  potential and in related to its flavonoid content and the use of ethyl acetate as the extraction solvent.  This study reveals the potential of A. cina as a natural antibacterial agent. 
Co-Authors ,, Djohan Agna Sulis Krave Agung Rimayanto Gintu Agung Rimayanto Gintu Agung Rimayanto Gintu Alberthnico, Ferdian Andreas Binar Aji Sukmana Anggara Mahardika Araujo, Otilda Fatima Ari Hasna Widyapuspa Cahyaningrum, D C. Cahyaningrum, Desti Christian Djurubasa, Dani Karel Marthin Egarani, Grahita Rezhi Grahita Rezhi Egarani Hartati Sulastri Hastuti, S P. Ie, Johanes Juan Yutama Putra Indrianasari, Putri Jeanelsin A.P Langgori Kasmiyati, S Keliat, Natalia Rosa Lilik Linawati Maria Marina Herawati Nabila, Nabila Natalia Rosa Keliat Priyayi, Desi Fajar Purwoko, Agus Putra Ie, Johanes Juan Yutama Putri, A C. Rahardja, P M. Ramagita, Marsahanda Astri Rimanti, Audri Septina Putri Rully Adi Nugroho Setiyarini, Chatarina Titik Siahaya, Esty Vicariat Sri Kasmiyati Sri Yulianto Sucahyo Sucahyo, S Trisianna, Jessica Ayu Trisianna Utomo, Daniel Setyo Vincentia Irene Meitiniarti Wardani, Yulia Kusma Wicaksono, Rifky Adi Yayi Suryo Prabandari Yohanes Martono Yusta, G. Maria