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MAHKOTA DEWA (PHALERIA MACROCARPA) SEBAGAI ANTINEFROTOKSISITAS “DEWA PENYELAMAT” DALAM PENURUNAN EFEK SAMPING CISPLATIN Zulharini S, Meirizky; L.R, Annishfia; Hidayah, Siti Nurul; Iman, Naisbitt
Program Kreativitas Mahasiswa - Penelitian PKM-P 2013
Publisher : Ditlitabmas, Ditjen DIKTI, Kemdikbud RI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (605.678 KB)

Abstract

Cisplatin is one of the most widely used chemotherapeutic agent in cancer treatment, however it possess series of harmful adverse effects, most notably, nephrotoxicity. Due to that reason, a natural chemopreventive agent is needed to minimize cisplatin’s toxicity, namely, Mahkota Dewa fruit (Phaleria marcocarpa) extract. This research aim to determine anti nephrotoxic effect of mahkota dewa fruit on Vero cells, model of renal cells. Cytotoxic assay of mahkota dewa’s extract and cisplatin both single and combination was determined using MTT assay on HeLa cells and Vero cells. The cytotoxic assay resulted that IC50 value of cisplatin and Mahkota Dewa to HeLa cells were 18µM (5,4 µg/mL) and 845 µg/mL, respectively, whereas the IC50 value of cisplatin and Mahkota Dewa to Vero were 80 µM (24 µg/mL) and 730 µg/mL, respectively. The results indicated that cisplatin was more cytotoxic to HeLa cell in comparison to Vero cell. Combination treatment of mahkota dewa’s extract at 183 µg/mL and cisplatin 284 µM showed increased viability of Vero cells. Therefore, combination treatment of cisplatin and mahkota dewa are able to decrease nephrotoxicity of cisplatin to renal cells.  Keyword: Mahkota dewa, cisplatin, flavonoid, nephrotoxicity, HeLa cell, Vero cell
TESTING OF WORK-FAMILY ENRICHMENT THROUGH WORK ENGAGEMENT Hidayah, Siti Nurul; palupiningdyah, palupiningdyah
Management Analysis Journal Vol 8 No 3 (2019): Management Analysis Journal
Publisher : Universitas Negeri Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/maj.v9i3.33404

Abstract

This study aims to determine the effect of job crafting and leader-member exchange on work-family enrichment through work engagement on married women  employees in the finishing department of PT Sandang Asia Maju Abadi. The type and design of the research used in this study is quantitative research. Sampling in this study used a probability sampling and obtained the sample size that must be used is 127 employees. Methods of data collection using a questionnaire with a Likert scale 1-5. The analytical method used is the test instrument (validity and reliability), hypotheses testing and path analysis test with SPSS 23. The results of the study show that all hypotheses are accepted. Therefore could be known that job crafting has a positive effect on work engagement. Leader-member exchanges have a positive effect on work engagement. Job crafting has a positive effect on work-family enrichment. Leader-member exchanges have a positive effect on work-family enrichment. Work engagement has a positive effect on work-family enrichment. The path analysis test results also show that job crafting has a positive effect on work-family enrichment and leader-member exchange that has a positive effect on work-family enrichment through work engagement.
PENGEMBANGAN BAHAN AJAR IPS BERBASIS KERAGAMAN BUDAYA BATIK JENOGOROAN UNTUK MENINGKATKAN BERPIKIR KRITIS SISWA Hidayah, Siti Nurul
Ed-Humanistics : Jurnal Ilmu Pendidikan Vol 4 No 1 (2019): Ed-Humanistics
Publisher : Fakultas Ilmu Pendidikan (FIP) Universitas Hasyim Asy'ari (Unhasy) Tebuireng Jombang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1749.246 KB) | DOI: 10.33752/ed-humanistics.v4i1.362

Abstract

AbstractThis study aims to improve critical thinking through the development of social sciencesteaching material toward cultural diversity batik jenogoroan in students class VII SMPN 2Bojonegoro. The research was conducted in three stages following the draft Borg and Gall, thatis the preliminary studies aimed, the stage of product designing teaching materials students withthe module, and continued with the testing stage or stages of implementation in the classroomdesign was one group pretest-posttest design. Data from the research results obtained asfollows: (1) the feasibility of module based cultural diversity batik jenogoroan worthy usedthrough 3 expert validation test, the feasibility of module seen from three components: content,presentation, and language. The results of the validation of third validator namely: the averagescore of the content component 3.53, 3.40 linguistic components, and presentation componentsof 3.55. All three scores indicate good category/feasible, which means module based culturaldiversity-based batik jenogoroan can be used with minimal revision. (2) the effectiveness ofmodule toward cultural diversity batik jenogoroan can enhance students' critical thinking can beseen from the test results between the pre-test and post-test, the results showed that the averagescore pre test 72.13%, while the average score of post test 80.35%. The results of the pre-test topost-tets increased 8.22. Based on the analysis, it can be concluded that based teachingmaterials cultural diversity batik jenogoroan can effectively improve critical thinking students'VII classes in social studies, especially on the matter of cultural diversity when seen from thetest results that have increased.Keywords: Teaching Materials, Cultural Diversity, Batik Jenogoroan, Critical Thinking
PENGEMBANGAN SPECIES IDENTIFICATION GUIDE POHON DAN PERDU SEBAGAI SARANA IDENTIFIKASI KEANEKARAGAMAN TUMBUHAN DI SEKOLAH Hidayah, Siti Nurul; Wisanti, Wisanti; Putri, Eva Kristinawati
Berkala Ilmiah Pendidikan Biologi (BioEdu) Vol 7 No 2 (2018)
Publisher : Program Studi Pendidikan Biologi, FMIPA, Universitas Negeri Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Sarana identifikasi merupakan salah satu alat yang digunakan dalam membantu proses identifikasi. Sarana identifikasi tumbuhan yang diperuntukkan bagi siswa di sekolah masih terbatas. Tujuan penelitian ini adalah menghasilkan SIG pohon dan perdu Keanekaragaman Tumbuhan di Sekolah yang layak secara teoretis dan empiris, mendeskripsikan kelayakan SIG pohon dan perdu secara teoretis berdasarkan hasil validasi, dan secara empiris berdasarkan pengamatan aktivitas siswa, respons guru, respons siswa dan komentar siswa terhadap SIG. Penelitian ini merupakan penelitian pengembangan menggunakan model instruksional Fenrich yang terdiri dari tahap analisis, perencanaan, perancangan, pengembangan, implementasi, dan tahap evaluasi serta revisi yang dilakukan pada setiap akhir tahapan.Tahap analisis, perencanaan, dan perancangan dilakukan di Jurusan Biologi Unesa. Uji coba terbatas dilakukan pada 10 siswa dari SMAN 1 Kalitidu dan 10 siswa dari SMA Muhammadiyah 2 Surabaya. Parameter penelitian ini mencakup hasil validitas, aktivitas siswa, respons siswa, respons guru yang dianalisis secara deskriptif kuantitatif dan komentar siswa terhadap SIG dianalisis secara deskriptif kualitatif. Hasil penelitian menunjukkan bahwa SIG pohon dan perdu layak digunakan sebagai sarana identifikasi. Kelayakan SIG secara teoretis berdasarkan hasil validasi dinyatakan sangat layak. Kelayakan empiris berdasarkan pengamatan aktivitas siswa dinyatakan sangat aktif, berdasarkan respons guru dan respons siswa dinyatakan sangat layak, dan mendapatkan komentar positif dari siswa. SIG Pohon dan Perdu dinyatakan layak digunakan sebagai saran identifikasi tumbuhan.                                                                                                                                         Kata Kunci: Keanekaragaman Tumbuhan, Pohon dan Perdu, Sarana Identifikasi, Species Identification Guide
Peranan Ulama Muhammadiyah dalam Pembentukan APS (Askar Perang Sabil) di Yogyakarta Tahun 1947-1949 Hidayah, Siti Nurul; Birsyada, Muhammad Iqbal
Historia: Jurnal Pendidik dan Peneliti Sejarah Vol 5, No 1 (2022): Kreativitas dalam Pembelajaran Sejarah
Publisher : Prodi. Pendidikan Sejarah FPIPS UPI dan APPS (Asosiasi peneliti dan Pendidik Sejarah)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (161.883 KB) | DOI: 10.17509/historia.v5i1.34537

Abstract

Tujuan penelitian ini adalah untuk mengetahui: (1) Bagaimana Gambaran umum Yogyakarta Pada Masa Revolusi Fisik di Indonesia (2) Bagaimana Gambaran Umum Ulama Masa Revolusi Fisik di Yogyakarta (3) Bagaimana Peranan Ulama Muhammadiyah dalam Pembentukan APS (Askar Perang Sabil) di Yogyakarta. Metode yang digunakan dalam penelitian ini adalah Literatur dengan lima tahapan, yakni: (1) Pemilihan topik, menentukan pokok-pokok masalah yang akan diteliti, (2) Heuristik, (3) Kritik sumber, (5) Historiografi, penyusunan sejarah secara kronologis sehingga tersusunlah penulisan sejarah. Hasil penelitian ini menunjukkan (1) Revolusi Fisik di Yogyakarta terjadi karena beberapa hal yaitu, Agresi Militer Belanda I, Pemberontakan PKI di Gunungkidul, Agresi Militer Belanda II dan Serangan Umum 1 Maret, (2) Pada masa Revolusi Fisik di Yogyakarta, Para ulama seperti NU, MIAI memiliki peranan dalam memperjuangkan kemerdekaan salah satunya yaitu dalam mendirikan laskar-laskar islam seperti Hisbullah dan Sabilillah (3) para ulama di Yogyakarta yaitu Muhammadiyah juga ikut berpartisipasi pada masa Revolusi Fisik yaitu dalam pembentukan APS dan dalam memberikan latihan-latihan Fisik, Idiologi dan Kerohanian. 
Testing of Work-Family Enrichment through Work Engagement Hidayah, Siti Nurul; palupiningdyah, palupiningdyah
Management Analysis Journal Vol 8 No 3 (2019): Management Analysis Journal
Publisher : Universitas Negeri Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/maj.v9i3.33404

Abstract

This study aims to determine the effect of job crafting and leader-member exchange on work-family enrichment through work engagement on married women employees in the finishing department of PT Sandang Asia Maju Abadi. The type and design of the research used in this study is quantitative research. Sampling in this study used a probability sampling and obtained the sample size that must be used is 127 employees. Methods of data collection using a questionnaire with a Likert scale 1-5. The analytical method used is the test instrument (validity and reliability), hypotheses testing and path analysis test with SPSS 23. The results of the study show that all hypotheses are accepted. Therefore could be known that job crafting has a positive effect on work engagement. Leader-member exchanges have a positive effect on work engagement. Job crafting has a positive effect on work-family enrichment. Leader-member exchanges have a positive effect on work-family enrichment. Work engagement has a positive effect on work-family enrichment. The path analysis test results also show that job crafting has a positive effect on work-family enrichment and leader-member exchange that has a positive effect on work-family enrichment through work engagement.
Hubungan Pengetahuan, Pelayanan Petugas Kesehatan, serta Media Informasi terhadap Kepatuhan Melakukan Antenatal Care di PMB E Tahun 2022: Relationship between Knowledge, Health Officer Services, and Information Media on Compliance with Antenatal Care in PMB E in 2022 Hidayah, Siti Nurul
Open Access Jakarta Journal of Health Sciences Vol 3 No 3 (2024): Open Access Jakarta Journal of Health Sciences
Publisher : Sagamedia Indo Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53801/oajjhs.v3i3.239

Abstract

Pendahuluan: Kepatuhan berarti bersifat patuh, ketaatan, tunduk, patuh pada ajaran dan aturan. Kepatuhan adalah mengikuti suatu spesifikasi, standar, atau hukum yang telah diatur dengan jelas yang biasanya diterbitkan oleh lembaga atau organisasi yang berwenang dalam suatu bidang tertentu. Tujuan: Untuk mengetahui hubungan  pengetahuan, pelayanan petugas Kesehatan serta media informasi terhadap kepatuhan melakukan ANC di PMB E tahun 2022. Metode: Jenis penelitian ini kuantitatif menggunakan metode analitik dengan pendekatan cross-sectional. Metode  penelitian  yang  digunakan adalah  metode cross-sectional. Penelitian dilaksanakan pada bulan September sampai Oktober 2022 dimana penelitian dilakukan pada saat pengambilan data antara variabel independen dengan variabel dependen yang dilakukan secara bersama-sama pada waktu yang sama, sampel pada penelitian ini 60 responden, telah dilakukan uji validitas dan keseluruhan instrumen yang digunakan adalah valid. Instrument yang digunakan dalam pengumpulan data dalam penelitian ini berupa lembar kuisioner. Analisis data menggunakan uji chi-square. Hasil: Hasil analisis menunjukan hubungan pengetahuan dengan nilai P-value 0,025 dan Nilai OR 4.000, hubungan pelayanan petugas kesehatan, dengan nilai P-value 0,001 dan Nilai OR 7.716, dan hubungan media informasi Tahun 2022 dengan nilai P-value 0,009 dan Nilai OR 5.028. Kesimpulan: Terdapat hubungan pengetahuan, pelayanan petugas Kesehatan serta media informasi terhadap kepatuhan melakukan antenatal care di PMB E tahun 2022.
Blended Learning Approach Implementation to Improve Adults’ Tahsin Ability in the Digital Era Tiarawati, Putri Vidi; Nurhayati, Sri; Hidayah, Siti Nurul; Boriboon, Gumpanat
Cendekia: Kependidikan dan Kemasyarakatan Vol 21 No 2 (2023)
Publisher : IAIN Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21154/cendekia.v21i2.7111

Abstract

This study aims to determine the extent of Tahsin Al-Qur'an learning improvement using a blended learning approach among adult learners at Sekolah Ibu Bandung. This study employed a qualitative approach with a case study method. 13 Tahsin teachers and 130 adult learners participated in this study. From the thorough interview results, observation and document study revealed that after involving 6 phases of blended learning program implementation, the adult learners in all Tahsin levels highly increased their Tahsin learning proficiencies. This blended approach has been met with enthusiasm from both educators and learners, with many lauding its flexibility, active engagement opportunities, and the nurturing mentorship it fosters during face-to-face sessions. The structured design and execution of this program have been pivotal in amplifying learners' comprehension of Tahsin Al-Qur’an concepts. From this study findings, the blended learning approach in Tahsin Al-Qur’an learning can be broadly adopted to general learners to improve their Tahsin aptitudes.
DISCIPLINE ATTITUDE OF ELEMENTARY SCHOOL STUDENTS ON DISTANCE LEARNING Hadi, Waluyo; Lestari, Ika; Nafiah, Maratun; Hidayah, Siti Nurul
PARAMETER: Jurnal Pendidikan Universitas Negeri Jakarta Vol. 33 No. 2 (2021): Parameter
Publisher : Lembaga Penelitian dan Pengabdian Kepada Masyarakat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21009/parameter.332.04

Abstract

The Covid-19 pandemic has hit Indonesia for about a year, and many activities have shifted online. No exception in the field of education. Learning is done online or in distance learning. The existence of distance learning does not rule out the possibility of bringing a change, including student discipline. This study has a purpose, namely to determine the field of elementary school students during distance learning. Descriptive quantitative is used as a method in conducting this research. Respondents in this study were 41 students at the State Elementary School 02 Pagelaran, Pemalang, Central Java. Filling out the questionnaire was used as a way to collect data. The results showed that at the time of distance learning, students' discipline was included in the moderate category with 46%, and the results could not be generalized to all elementary school levels in Indonesia.
Pengaruh modal, jam kerja, dan lama usaha terhadap pendapatan UMKM counter pulsa di Kecamatan Pace Hidayah, Siti Nurul; Estiningrum, Sri Dwi
Fair Value: Jurnal Ilmiah Akuntansi dan Keuangan Vol. 5 No. 3 (2022): Fair Value: Jurnal Ilmiah Akuntansi dan Keuangan
Publisher : Departement Of Accounting, Indonesian Cooperative Institute, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32670/fairvalue.v5i3.2423

Abstract

One of the demands that are now emerging due to globalization and technological advances, where people are now starting to become familiar with smartphone technology is the credit purchase service. To be able to survive in the midst of intense business competition, especially if competitors have better human resources and application of technology, the existing credit counter MSMEs compared to start-up companies should have strong capital in order to maintain their existence and consumers. This study aims to determine the effect of capital, working hours, and length of business on the income of UMKM counter pulses located in Pace District. This research is a quantitative research with the data used are primary data and secondary data. The research instrument is a questionnaire. The results of this study are the variables of capital, length of work, and length of business have a positive and significant influence on the income of UMKM counter pulses in Pace District. From the results of these studies, it can be concluded that the greater the capital and the longer the work and business, the higher the income of UMKM counter pulses in Pace District.