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All Journal Pharmaciana: Jurnal Kefarmasian Althea Medical Journal Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Berkala Ilmiah Kedokteran Duta Wacana PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) JKKI : Jurnal Kedokteran dan Kesehatan Indonesia eJournal Kedokteran Indonesia MEDICINUS Acta Neurologica Indonesia Jurnal Penelitian Keperawatan
Rizaldy Taslim Pinzon
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Education Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health

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PERBANDINGAN NILAI INDEKS CASTELLI RISK II PADA FAKTOR RESIKO STROKE ISKEMIK SERANGAN PERTAMA Zenine Charolin Sinulingga; Rizaldy Taslim Pinzon; Loury Priskila; MMA Dewi Lestari
Jurnal Penelitian Keperawatan Vol 12 No 1 (2026): Jurnal Penelitian Keperawatan
Publisher : STIKES RS Baptis Kediri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32660/jpk.v12i1.925

Abstract

Background: Ischemic stroke is the most common type of stroke and a leading cause of disability and death. One of its major risk factors is dyslipidemia, which can be assessed using the Castelli Risk Index II (CRI-II), calculated as the ratio of LDL to HDL. A high CRI-II indicates increased atherogenic potential and a higher likelihood of stroke occurrence, particularly the first event. Objective: This study aims to determine the comparison of CRI-II values based on ischemic stroke risk factors such as hypertension, age, sex, diabetes mellitus, smoking status, and lipid profiles in patients with first-onset ischemic stroke. Methods: This was a descriptive analytic study using a cross-sectional approach and secondary data from 120 ischemic stroke patients aged 40–59 years across several hospitals in Yogyakarta. Data analysis was conducted using the Kolmogorov-Smirnov normality test and the chi-square test to assess relationships between variables. Results: Most patients (55%) had high CRI-II values (>3.5). No significant differences in CRI-II were found based on hypertension, age, sex, smoking status, or history of diabetes mellitus. However, there was a significant association between high LDL levels and CRI-II values (p=0.001), indicating the dominant role of LDL in increasing atherosclerotic risk, as LDL is directly involved in the CRI-II calculation. Conclusion: There were no significant differences in CRI-II values across most analyzed risk factors, except for LDL levels. This highlights the importance of lipid control, especially LDL, in preventing first-time ischemic stroke.
Co-Authors Abraham Al Jody Adi Utarini Aditya Aristo Marvel Nugroho Aditya Batlajery Alfajri, Novi Zain Andre Darmawan Wiyono Caecilia Lelia Rahmawati Daniel Mahendra Krisna Daniel Mahendra Krisna Diah Mutiarasari Dyah Wulaningsih Retno Edi Edenia Asisaratu Eka Ari Wibawa Erna Kristin Esdras Ardi Pramudita Florence Florence Gavrila, Priska Gian Gunadi Gunadi Hardi Astuti Witasari Hariatmoko . Hariatmoko Hariatmoko Ivana Prasetianingtyas Ivana Purnama Dewi Jerry Tanhardjo Kadek Reisya Sita Damayanti Kristina Reny Indriawati Kriswanto Widyo Larasati, Yutta Lisa Kurnia Sari Loury Priskila Maria Silvia Merry MMA Dewi Lestari Nicholas Adriel Pinzon Nunki Puspita Utomo Pudji Sri Rasmiati Sugaianto Adisaputro Sugianto Sugianto Tiara Kusumaningtyas Tiara Triasari Tillandsia Filli Folia Primastuti Tjahjono Kuntjoro Trisasi Lestari Vincent Exel Susanto Yohana Puji Dyah Utami Zenine Charolin Sinulingga