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All Journal CALYPTRA : Jurnal Ilmiah Mahasiswa Universitas Surabaya MPI (Media Pharmaceutica Indonesiana) Indonesian Journal of Chemistry Dinamisia: Jurnal Pengabdian Kepada Masyarakat JSFK (Jurnal Sains Farmasi & Klinis) Pharmaceutical Journal of Indonesia Abdimas: Jurnal Pengabdian Masyarakat Universitas Merdeka Malang Hubungan Tingkat Pengetahuan Petugas Pengelola Obat dengan Tingkat Ketersediaan Obat Di Puskesmas Kota Malang Journal Of World Science Pharmaceutical Sciences and Research (PSR) Eduvest - Journal of Universal Studies Jurnal Sains dan Kesehatan
Azminah Azminah
Fakultas Farmasi Universitas Surabaya
Aerospace Engineering Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Economics, Econometrics & Finance Education Engineering Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Public Health Social Sciences Other

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Implementation of process technology and diversification of Astiri Oil products to improve community economy Gondokesumo, Marisca Evalina; Azminah, Azminah; Ardiansyahmiraja, Bobby; Suryaningsih, Dwie Retna
Abdimas: Jurnal Pengabdian Masyarakat Universitas Merdeka Malang Vol. 10 No. 1 (2025): February 2025
Publisher : University of Merdeka Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26905/abdimas.v10i1.14830

Abstract

Jatijejer Village, located between the slopes of Mount Penanggungan and Mount Welirang, has significant potential for cultivating aromatic plants, particularly lemongrass (Cymbopogon citratus) and citronella (Cymbopogon nardus). These plants are sources of essential oils with various benefits, including uses in aromatherapy, antibacterial, and anti-inflammatory applications, and are widely utilized in the cosmetics and healthcare industries. Despite this potential, the community of Jatijejer Village previously only utilized lemongrass as raw material, yielding suboptimal economic value and welfare improvement. This community service program aims to enhance the welfare of Jatijejer Village through the production and diversification of essential oil-based products. Activities included training in steam distillation techniques, quality measurement of essential oils, and the development of derivative products such as inhalers and diffusers. Evaluation results showed a significant improvement in participants' knowledge and skills. The average pre-test score of 58.4 percent increased to 97.2 percent in the post-test. Additionally, the essential oils produced were successfully developed into value-added products, such as inhalers and diffusers, which have begun to be marketed locally. Solid waste from the distillation process was also utilized as organic fertilizer, reinforcing the program's sustainability. This training effectively improved the skills, income, and economic independence of the Jatijejer Village community.
Diabetic Foot Ulcer (DFU) Gene Expression in Homo Sapiens Species Wulandini Putri, Adquinta; Azminah, Azminah
Journal of World Science Vol. 2 No. 6 (2023): Journal of World Science
Publisher : Riviera Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58344/jws.v2i6.329

Abstract

Diabetic foot ulcer (DFU) is a major problem in people with diabetes because more than 15% of patients have to treat DFU during their lifetime. 1 out of people with diabetes can experience a diabetic foot ulcer (DFU). At least a quarter of diabetic foot ulcer (DFU) sufferers cannot recover completely. The prevalence of diabetic foot ulcers (DFU) in Indonesia reaches 8.7%. The current DFU treatment approved by the FDA uses Becaplermin, a recombinant platelet-derived growth factor derivative. However, this treatment has a weakness in systemic bioavailability. FAgene expression analysis method is needed. to develop other therapies. This article aims to discover specific genes that play a role in diabetic foot ulcer (DFU) wound healing. In this systematic review, we searched the GEO Data Sets database to identify articles published from 2018 to 2023. The search results for DFU gene expression data for all species obtained 130 articles. Then, the DFU gene expression data series of Homo sapiens species was filtered to obtain ten related articles. This research has implications in providing better insight into the specific genes involved in the healing process of DFU wounds. This research also has the potential to contribute to early diagnosis of DFU injuries and better treatment.
Gene Expression Data Analysis In Response to Nicotine Exposure: a Literature Study Revealing Differentially Expressed Genes In Biological Pathways Azminah, Azminah; Munawwarah, Munawwarah
Journal of World Science Vol. 2 No. 12 (2023): Journal Of World Science
Publisher : Riviera Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58344/jws.v2i12.500

Abstract

This research aims to deepen our understanding of the effects of nicotine usage through a descriptive literature review, with the primary focus on exploring GEO DataSets via the analysis of Differentially Expressed Genes (DEGs) in response to nicotine exposure. The GEO DataSet search was obtained from the National Center for Biotechnology Information (NCBI) Gene Expression Omnibus (GEO), a relevant biomedical data source. The results of our investigation revealed a total of 11 GEO DataSets of Homo sapiens that met the inclusion and exclusion criteria for identifying Differentially Expressed Genes (DEGs). These datasets, namely GSE125217, GSE148812, GSE125416, GSE105445, GSE56398, GSE51284, GSE71795, GSE56383, GSE40689, GSE11208, and GSE11142, contained genes that underwent altered expression in response to nicotine exposure. The results of the gene analysis were further categorized based on their functional classifications. They encompass receptor genes such as CHRNA9, nAChRs, and TLR4, regulatory genes including CDK1, CHK1, ERBB2, EGFR, and E2F1, structural genes like H-Caldesmon, L-Caldesmon, SM22, CDH1/3, BDNF/NT-3, and MLL3, immunological genes such as TNF-?, IL-1?, IL-6, IL-10, MCSF, MCP-1, and ICAM-1, metabolic genes like CYP2A6 and APOE, and enzymatic genes such as PITRM1, DDR2, DHRS7, and SLC16A7. This review search provides a comprehensive insight into the molecular-level impact of nicotine, with potential implications for the development of treatment strategies and the discovery of relevant biomarkers associated with nicotine use.
Essential Oils and Mindfulness Exercises in Influencing Gene Expression Involved in Mild Cognitive Impairment (MCI): A Systematic Review Santoso, Vania Joceline; Azminah, Azminah
Eduvest - Journal of Universal Studies Vol. 4 No. 10 (2024): Journal Eduvest - Journal of Universal Studies
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/eduvest.v4i10.1692

Abstract

Mild Cognitive Impairment (MCI) represents a transitional stage between normal cognitive function and dementia, affecting memory and other cognitive abilities. This systematic review explores the impact of essential oils and mindfulness exercises on gene expression involved in MCI. Despite the prevalence of pharmacological treatments, they offer limited prevention of MCI progression to dementia. Non-pharmacological interventions, such as mindfulness exercises, have demonstrated cognitive benefits, albeit with moderate efficacy. Essential oils, used in aromatherapy, show promise in supporting cognitive improvement through their impact on amyloid-beta and cholinesterase pathways. This review synthesizes findings from multiple studies between 2017 and 2024, highlighting that combining essential oils and mindfulness exercises may offer enhanced therapeutic outcomes for individuals with MCI. Further research is needed to establish the efficacy of this integrative approach, which could slow the progression of MCI and improve patients' quality of life.
Knowledge Enhancement Through Field Learning : Development Jatijejer Village Into The First Atsiri Village in East Java, Indonesia: Peningkatan Pengetahuan Melalui Pembelajaran Lapangan : Transformasi Jatijejer Menjadi Desa Atsiri Pertama di Jawa Timur Gondokesumo, Marisca Evalina; Azminah, Azminah; Ardiansyahmiraja, Bobby; Suryaningsih, Dwie Retna
Dinamisia : Jurnal Pengabdian Kepada Masyarakat Vol. 9 No. 1 (2025): Dinamisia: Jurnal Pengabdian Kepada Masyarakat
Publisher : Universitas Lancang Kuning

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31849/dinamisia.v9i1.22963

Abstract

Jatijejer Village located in Trawas Subdistrict, Mojokerto, East Java, has significant potential in agriculture due to its fertile soil but this potential has not been fully optimized. The main crops widely cultivated there are lemongrass (Cymbopogon citratus (DC.) Stapf) and citronella (Cymbopogon nardus (L.) Rendle), which can be processed into essential oils with high economic value and various other benefits. The initial effort in developing Jatijejer Village into the first Atsiri Village in East Java is field learning, which provides a comprehensive overview of the target goals. Hortus Medicus and Rumah Atsiri Indonesia in Tawangmangu, Central Java, were chosen due to their experience in cultivating and processing aromatic plants and producing essential oils. This field learning involved 30 participants, including village officials, representatives of farmer groups, PKK, BUMDES of Jatijejer Village, and community service teams from the University of Surabaya and Wijaya Kusuma University Surabaya. Each participant completed pretests and posttests to measure knowledge improvement after the field learning. The results showed an increase in participants' knowledge, with an average pretest score of 58% rising to 98% in the posttest. This field learning activity proved effective in enhancing participants' knowledge, supporting the success of the village development program, and optimizing the economic and tourism potential of Jatijejer Village.
Co-Authors Abdul Mun’im Ahdyani, Risa Amarila Malik Andika Andika Andre Tanzil Angga Cipta Narsa Ardiansyahmiraja, Bobby Arry Yanuar Berna Elya Ebry Ryanata Ebry Ryanata, Ebry Erlina, Linda Erwin Samsul Erwin Samsul Gemini Alam Hadi Kuncoro Hanita Omar Hariyanti Hariyanti Hayun Hayun, Hayun Islamudin Ahmad Iswahyudi Iswahyudi Kesuma, Dini Kusuma Hendrajaya Lekal, Tresia M. Arifuddin Marisca Evalina Gondokesumo, Marisca Evalina Michella Michella Muhammad Hanafi Neneng Siti Silfi Ambarwati Noor Linda Febrianie Nur Jamailah Raden Mohamad Herdian Bhakti Rika Yulia Risna Agustina Risna Agustina Sajekti Palupi Sajekti Palupi Santoso, Vania Joceline Suryaningsih, Dwie Retna Wisnu Cahyo Prabowo Wulandini Putri, Adquinta Yuditya Artha