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FORMULATION AND PHYSICAL PROPERTIES OF CANDLENUT OIL GEL POMADE (Aleurites Mollocana Wild) Wilda Amananti; Aldi Budi Riyanta
Jurnal Farmasi Sains dan Praktis Vol 6 No 2 (2020)
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/pharmacy.v6i2.3162

Abstract

The use of pomade for a long time will cause hair damage. Pomade with preferred ingredients, because it is very good for beauty and hair health. Liquid oil is one of the basic ingredients used in making pomade. Candlenut oil can be used as liquid oil for the pomade base. This article examines the formulation and physical properties of pomade from candlenut oil. There are four formulas that have been made with different F0 candlenut oils without candlenut oil, F1 with 10% candlenut oil, F2 with 20% candlenut oil, F3 with 30% candlenut oil. The difference in concentration is indicated to affect the physical differences of the candlenut oil pomade. Physical properties of Candlenut Oil Pomade gel include organoleptic, homogeneity, scattering test, sticky test. The results showed that all formulas showed homogeneous gel preparations. Formula 3, with the highest concentration of candlenut oil concentration of 30%, shows a greater dispersion than a formula with other substances reaching 6.5 cm and meets SNI standards, which will increase the adhesion, which does not meet the standard.
Green Synthesis and Antibacterial Activity of Silver Nanoparticles using Turi (Sesbania grandiflora Lour) Leaf Extract Wilda Amananti; Aldi Budi Riyantal; Kusnadi Kusnadi; Kawther Ameen Muhammed Saeed Aledresi
EKSAKTA: Berkala Ilmiah Bidang MIPA Vol. 23 No. 04 (2022): Eksakta: Berkala Ilmiah Bidang MIPA (E-ISSN : 2549-7464)
Publisher : Faculty of Mathematics and Natural Sciences (FMIPA), Universitas Negeri Padang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24036/eksakta/vol23-iss04/337

Abstract

Research has been carried out on the ability of antibacterial activity with using Ag nanoparticles with a variation of the AgNO3 mole ratio of 0.5 mM and 1.5 mM as much as 90 ml and the amount of turi leaf extract added 1 mL. The material was characterized by UV-vis spectroscopy. Determination of antibacterial activity was carried out through Escherichia coli bacteria after interacting with nanoparticles Ag. Green synthesis of silver nanoparticles can be carried out using an aqueous extract of turi leaves, with the optimum concentration of 0.5 mM AgNO3 and 1.5 mM AgNO3 being synthesized for one day at room temperature. Resulting in silver nanoparticles with energy band gap values of 3.9 eV and 3.88 Ev having antibacterial activity of Escherichia coli with inhibitory power of 5.52 mm and 6.65 mm, respectively.   
Determination Of Total Flavonoid Content Of Bajakah Tampala And Kalalawit Roots Using The Reflux Sasi Yuni Kirana; Rizki Febrianti; Wilda Amananti
Indonesian Journal of Chemical Science and Technology (IJCST) Vol 6, No 1 (2023): JANUARY 2023
Publisher : Universitas Negeri Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24114/ijcst.v6i1.43183

Abstract

Bajakah is one of the plants found in the forest around Muara Badak. Bajakah root contains flavonoids which have potential as natural ingredients that have medicinal properties. Currently, there are two types of bajakah root on the market, namely tampala and kalalawit. This study aims to determine the content and total flavonoid content of the extract of the Bajakah root from the two types of Bajakah root. The research procedure was initiated by the process of extracting the roots of the Bajakah root using the reflux method using 96% ethanol. The reflux extraction results are then carried out by an evaporation process to obtain a thick extract. The second step is to test the flavone content through a color test. And the quantitative test for determining total flavonoid levels was carried out by UV-Vis Spectrophotometry. Based on the results of a qualitative test using a color reaction, it shows that the roots of the kalalawit and tampala bajakar contain flavonoids. Where the total flavonoid content in the roots of Bajakah Tampala was 59.38% and in Bajakah Kalalawi roots was 47.14%.
Analysis of Total Flavonoid Content in the Extract of Bajakah Kalalawit Root (Uncaria gambir Roxb) Infunded Results Nurul Reza Alfani; Rizki Febrianti; Wilda Amananti
Indonesian Journal of Chemical Science and Technology (IJCST) Vol 6, No 1 (2023): JANUARY 2023
Publisher : Universitas Negeri Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24114/ijcst.v6i1.43184

Abstract

Bajakah kalalawit is one of the plants that has been empirically used in traditional medicine. The roots of Bajakah kalalawit (Uncaria gambir Roxb) have phenol and antibacterial content and have a high enough content of flavonoid compounds so that they have pharmacological activity as an anticancer. This article examines the content of flavonoid compounds contained in the extract of Bajakah Kalalawi root and also examines the total levels of flavonoids contained in the roots of Bajakah Kalalawi. Bajakah kalalawit root extract was obtained by the infundation extraction method using a water solvent (1:10). Examination of the characteristics of the sample is carried out by macroscopic and microscopic identification. The qualitative test of flavonoids was carried out by color reaction tests in two treatments. Determination of flavonoid levels in the root extract of bajakah kalalawi was carried out by the UV-Vis spectrophotometry method. From the results of the study showed that the levels of flavonoids in the root extract of Bajakah Kalalawi in sample A were 33.2% and in sample B by 44.8%. The results showed that the roots of Bajakah Kalalawi were shown to contain flavonoid compounds.
Analysis of The Optical Properties of Ag Nanoparticles With The Assistance of Bioreductors of Saga Leaf Extract (Abrus pecatorius L.) Rahma Sofia Putri; Aldi Budi Riyanta; Wilda Amananti
Indonesian Journal of Chemical Science and Technology (IJCST) Vol 6, No 1 (2023): JANUARY 2023
Publisher : Universitas Negeri Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24114/ijcst.v6i1.43179

Abstract

Nanotechnology has become an important and interesting field of physics, chemistry, biology and engineering in recent years. The rapidly growing nanotechnology today is nanoparticles. The characteristic characteristic of nanoparticles is that the particle size is very small in the range (1-100 nm). Silver nanoparticles have been synthesized using saga leaf extract (Abrus pecatorius L.) as a reducing agent. The formation of silver nanoparticles was carried out by adding sage leaf extract to the AgNO3 solution and homogenizing using a magnetic stirrer for 60 minutes. UV-Vis spectrophotometer was used to confirm the formation of silver nanoparticles. Test the inhibition of bacteria using the well method. The results showed that the wavelength values were in the range of 375-395nm.
Determination of IC50 Root Extracts of Bajakah Tampala (Spatholobus littoralis Hassk) and Kalalawit (Uncaria gambir Roxb) Using DPPH Method Melsya Merdita; Rizki Febriyanti; Wilda Amananti
Jurnal Ilmiah Teknik Kimia Vol. 7 No. 1 (2023): JURNAL ILMIAH TEKNIK KIMIA
Publisher : Program Studi Teknik Kimia, Universitas Pamulang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32493/jitk.v7i1.25106

Abstract

Indonesia is one of the countries whose people use traditional medicine as an alternative medicine to treat various types of diseases, one of which is by using bajakah root. The purpose of this study was to determine the value of IC50 and compare the antioxidant activity of the steel root extract of tampala and kalalawit types. Research methods using experimental methods. The population used is the root of bajakah type tampala and kalalawite. Samples were obtained from an online shop with a simple random sampling technique.  Extracted using the reflux method. Determination of IC50 using the DPPH method (1,1- diphenyl-2- picrilhydrazyl). The results of the research on the IC50 value obtained from the roots of bajakah tampala are 46.7304 ppm, which is classified as having anti-ochistic activity and is very strong because it <50 ppm and kalalawit bajakah root of 53.1006  ppm is classified as having strong antioxidant activity because it >50-100 ppm. However, when compared to the vitamin C comparison solution which has a  lower value of IC50,  which is  14.6217 ppm, it has very strong antioxidant activity. The efficacy of this study value of IC50 in the roots of the tampala type of steel is lower, indicating a stronger antioxidant activity than the roots of the kalalawit type bajakah.
PENENTUAN AKTIVITAS ANTIOKSIDAN INFUDASI AKAR BAJAKAH TAMPALA (Spatholobus littoralis Hassk) DAN KALALAWIT (Uncaria Gambir Roxb) DENGAN METODE DPPH Hidayati Salsabila; Rizki Febriyanti; Wilda Amananti
Jurnal Crystal : Publikasi Penelitian Kimia dan Terapannya Vol. 5 No. 1 (2023): Penelitian Kimia dan terapannya 2023
Publisher : Program Studi Kimia, Fakultas MIPA, Universitas PGRI Banyuwangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36526/jc.v5i1.2583

Abstract

Radikal bebas yang bersifat reaktif terhadap sel dan jaringan tubuh dapat menjadi pemicu penyakit degeneratif. Antioksidan merupakan senyawa yang mampu menetralisir radikal bebas dalam tubuh manusia sehingga kerusakan sel dapat dicegah. Tanaman akar bajakah memiliki senyawa aktif yang berpotensi menjadi antioksidan. Penelitian ini bertujuan untuk mengetahui kandungan antioksidan dalam ekstrak yang dihasilkan dari proses infudasi akar bajakah tampala dan kalalawit. Ekstrak dibuat dengan metode infudasi menggunakan pelarut aquadest dengan perbandingan (1:10). Tahapan penelitian meliputi uji makroskopik, uji mikroskopis, skrining fitokimia dan penentuan aktivitas antioksidan dengan metode penekanan radikal bebas DPPH (2,2-diphenyl-1-picrylhydrazyl) dengan Spektrofotometer Uv-Vis. Analisis data penelitian ini berupa kualitatif, yaitu data disajikan dalam bentuk gambar dan tabel kemudian dideskripsikan hasilnya. Hasil penelitian menunjukkan bahwa akar bajakah mengandung senyawa alkaloid, saponin, flavonoid, tanin, dan terpenoid. Aktivitas antioksidan akar bajakah tergolong sedang yaitu pada jenis tampala memiliki aktivitas antioksidan dengan nilai IC50 sebesar 70,81 μg/mL dan pada tipe kalalawit memiliki nilai IC50 sebesar 71,77 μg/mL. Sedangkan perbandingan vitamin C termasuk antioksidan yang sangat kuat dengan nilai IC50 sebesar 22,37 μg/mL.
PENGARUH WAKTU MASERASI TERHADAP HASIL SKRINING FITOKIMIA PADA EKSTRAK DAUN MANGGA HARUM MANIS (Mangifera indica L.) Nur Afifah; Aldi Budi Riyanta; Wilda Amananti
Jurnal Crystal : Publikasi Penelitian Kimia dan Terapannya Vol. 5 No. 1 (2023): Penelitian Kimia dan terapannya 2023
Publisher : Program Studi Kimia, Fakultas MIPA, Universitas PGRI Banyuwangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36526/jc.v5i1.2634

Abstract

Skrining fitokimia tahap pendahuluan yang dapat memberikan gambaran mengenai kandungan pada senyawa tertentu dalam bahan alam yang akan diteliti. Skrining fitokimia dapat dilakukan, baik secara kualitatif maupun kuantitatif sesuai dengan tujuan yang diinginkan. Pelarut yang akan dugunakan dalam penelitian ini yaitu dengan etanol 70% dengan bertujuan untuk mengetahui adanya senyawa metabolite sekunder dengan perbedaan waktu maserasi pada ekstrak daun mangga harum manis (Mangifera indica L.). Ekstrak pada daun mangga harum manis dibuat dengan menggunakan metode maserasi dengan pelarut 70%. Hasil ektrak akan dilakukan uji kualitatif dan uji kuantitatif yang dimana uji kualitatif dengan mengunakan uji kromatografi lapis tipis (KLT) dan uji skrining fitokimia. Sedangkan uji kuantitatif dengan menggunakan uji spektrofotometri UV-Vis, mendapatkan kadar rata-rata pada kadar total flavonoid yaitu maserasi 1 hari sebesar 49,07%, maserasi 3 hari sebesar 29,27%, dan maserasi 5 hari sebanyak 18,67%.
Formulation and analysis of physical properties of Turi leaf extract suspension (Sesbania grandiflora L.) Wilda Amananti; ‪Rosaria Ika Pratiwi‬
Journal of Natural Sciences and Mathematics Research Vol 9, No 1 (2023): June
Publisher : Faculty of Science and Technology, Universitas Islam Negeri Walisongo Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21580/jnsmr.2023.9.1.13901

Abstract

Sesbania Grandiflora .L is a type of plant that has so many benefits in the treatment of various kinds Diseases include laxatives, pain relievers (analgesics), fever reducers (antipyretic), laxative urine (diuretic), and others. Almost all parts of This plant belonging to the genus Sesbania Grandiflora is efficacious as a medicine covering the skin stems, flowers, leaves and roots. Sesbania Grandiflora .L  contains alkaloid compounds, glycosides, flavonoids, saponins, tannins and phenols which give a positive reaction in the phytochemical screening assay. Turi leaf extract need to be made in the form of pharmaceutical dosage forms for ease of use. One preparation that can be applied is a suspension.In this study, turi leaf extract was used as the active substance. The suspension was made in 3 formulas with different concentrations of turi leaf extract. The finished suspension was tested for physical characteristics including organoleptic test, homogeneity test, pH test, density test and viscosity test.Based on the results of secondary metabolite tests, turi leaves contain alkaloids, flavonoids, tannins and saponins. Based on the results of testing the physical properties of the suspension, it showed that all formulas met SNI standards based on organoleptic, homogeneity, pH and density tests. while based on the viscosity test the suspension made does not meet SNI standards.
UJI IDENTIFIKASI BAKTERI Esherichia coli PADA JAMU GENDONG KUNYIT ASEM DI KABUPATEN TEGAL Inur Tivani; Wilda Amananti; Ahmad Sunardi
Parapemikir : Jurnal Ilmiah Farmasi Vol 8, No 1 (2019): Parapemikir : Jurnal Ilmiah Farmasi
Publisher : Pusat Penelitian dan Pengabdian Masyarakat Politeknik Harapan Bersama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30591/pjif.v8i1.1297

Abstract

Based on the results of previous studies conducted by researchers in January 2018 showed that the Total Plate Count (ALT) of Jamu Gendong in several villages in Talang sub-district did not meet the quality safety standards (ALT value of more than 104). The high ALT value indicates the presence of bacteria contained in the tamarind tamarind herbal medicine. One of the bacteria that often contaminates food and beverages or drugs is Escherichia coli. E. coli bacteria is a characteristic bacterium contaminated with food or drug samples. The purpose of this study is to test for the presence or absence of E coli bacteria in gedong kunyit asem herbal medicine in Tegal district.The identification test of E. coli bacteria was carried out through two techniques, namely staining and bacterial culture techniques. For coloring techniques, gram coloring tests will be carried out, while bacterial cultures include blood agar plates, and Macconkey agar media.The results showed that gram staining, as well as culture in the media of Blood Agar Plate and Macconkey Agar showed the presence of E. coli bacteria in samples of tamarind ancient tamarind in several villages in Tegal RegencyKeywords: identification test, Escherichia coli bacteria, Jamu genndong, Kunyit asem.