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All Journal Medula JPM (Jurnal Pengabdian Masyarakat) Ruwa Jurai
Anggraeni Janar Wulan, Anggraeni Janar
Bagian Anatomi, Fakultas Kedokteran, Universitas Lampung
Education Health Professions Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences

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Faktor-faktor yang Mempengaruhi Keberhasilan Terapi Pasien Kusta Sagia, Nabilla Alsa; Anggraini, Dwi Indria; Wulan, Anggraeni Janar; Sibero, Hendra Tarigan
Medula Vol 14 No 2 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i2.937

Abstract

Leprosy is a chronic granulomatous infectious disease caused by the obligate intracellular bacterium Mycobacterium leprae (M. leprae). This disease comes from the Latin word "lepros" which means scale. M. Leprae bacteria enter the human body through 2 main routes, namely through the skin and the upper respiratory tract. Leprosy bacilli enter the human body through direct contact with the skin or nasal mucosa originating from droplets. Bacteria from droplets will survive for 2 days in a dry environment, even up to 10 days in a humid environment and low temperatures. The success of therapy for Morbus Hansen patients is expressed by RFT (Release from Treatment). RFT can be stated after the dose is fulfilled without having to undergo laboratory examination. PB (paucibacillary) patients who have received 6 doses (blister) of treatment within 6-9 months are declared RFT, without having to undergo a laboratory examination. MB (multibacillary) patients who have received 12 doses (blister) of MDT treatment within 12-18 months are declared RFT, without having to undergo a laboratory examination. The factors that play a role in the success of therapy for leprosy patients are age, gender, education, employment, knowledge, compliance with taking medication, and family support.
Kerusakan, alkohol, kesehatan Kerusakan Lambung Akibat Konsumsi Alkohol: Dampak dan Penanganannya Madina Ghassan Nebraska; Jausal, Annisa Nuraisa; Wulan, Anggraeni Janar; Rudiyanto, Waluyo
Medula Vol 14 No 3 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i3.984

Abstract

Alcohol consumption has spread across various social strata of society, especially among teenagers. Health issues caused by alcohol are often overlooked. This article delves into the damage to the stomach caused by alcohol consumption. Alcohol can damage the gastric mucosa layer and disrupt the balance of stomach acid, leading to various conditions such as gastritis, gastric ulcers, and even gastric cancer. Additionally, alcohol can affect the movement of food and fluids in the digestive tract, increasing the risk of acid reflux, which can worsen stomach conditions. The mechanisms of stomach damage by alcohol involve the direct toxic effects of alcohol itself and the chronic inflammation it induces. Although this damage is often not immediately felt, its long-term effects can lead to serious complications. Management of alcohol-induced stomach damage involves lifestyle modifications, such as reducing or ceasing alcohol consumption, and medical treatment to alleviate symptoms and accelerate healing. To prevent further damage, it is important to raise awareness of the risks of alcohol to stomach health and promote a healthy lifestyle. Understanding the impact and management of stomach damage caused by alcohol consumption is crucial in preventing more serious complications.
Pengaruh Pemberian Ekstrak Biji Kopi Robusta (Coffea canephora) Lampung Terhadap Gambaran Histopatologi Tubulus Proksimal Ginjal Tikus Putih (Rattus norvegicus) Jantan Galur Sprague-dawley yang Diinduksi Monosodium Glutamat Salsabila, Aina; Wulan, Anggraeni Janar; Rodiani, Rodiani
Medula Vol 14 No 7 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i7.1335

Abstract

Excessive consumption of monosodium glutamate can form free radicals and is nephrotoxic which causes damage to organs, one of which is the kidneys, especially in the proximal tubule. Chlorogenic acid compounds contained in coffee beans have potential as antioxidants and nephroprotective agents. Coffee consumption at a certain dose is assumed to prevent and or reduce damage to the proximal kidney tubules of rats caused by free radicals. This research is an experimental study with a completely randomized design (CRD) with a Posttest Only Control Group Design approach. This research was conducted for 14 days. The samples used were 25 rats which were divided into 5 groups, namely K- (aquades 3 ml/day), K+ (MSG 4 g/kgBW/day), P1, P2, and P3 (MSG 4 g/kgBW/day). and Lampung robusta coffee bean extract 1 ml/200gBW/day with a concentration of 0.006 g/ml; 0.012 g/ml; 0.024 g/ml respectively) with each group consisting of 5 rats. Kidney histopathological assessment was carried out by observing kidney preparations in 5 visual fields each in 400x magnification. The mean total score of proximal tubular damage in groups K-, K+, P1, P2, and P3 respectively was 2.48; 3.40; 2.80; 2.64; 3.04. One Way ANOVA test obtained p value = 0.001 (p <0.05). Post Hoc LSD test on proximal tubular damage scores showed a significant difference (p<0.05) between K- and K+ (p=0.000), K- and P3 (p=0.008), K+ and P1 (p=0.005) , K+ with P2 (p=0.001), and P2 with P3 (p=0.047). There is an effect of administration of Lampung Robusta (Coffea canephora) coffee bean extract on the histopathological appearance of the kidney proximal tubules of male rats (Rattus norvegicus) strain Sprague-Dawley induced by monosodium glutamate.
HUBUNGAN KADAR HBA1C DENGAN DERAJAT ULKUS DIABETIK MENURUT KLASIFIKASI MEGGITT-WAGNER PADA PASIEN DIABETES MELITUS TIPE 2 DI RSUD DR. H. ABDUL MOELOEK BANDAR LAMPUNG PERIODE JANUARI-JULI 2022 Salsabila, Kamila; Kurniati, Intanri; Wulan, Anggraeni Janar; Wintoko, Risal
Medula Vol 16 No 1 (2026): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v16i1.1718

Abstract

Type 2 diabetes mellitus can lead to various complications if they are not managed adequately, including diabetic ulcers. Classification of diabetic ulcers is necessary to describe the lesion and to study the prognosis of the patients. The Meggit-Wagner classification was chosen because it is a classification system that has many advantages. Measurement of glycated hemoglobin (HbA1C) is a glycemic control that is considered good for describing blood sugar levels. High blood glucose levels are one of the reasons why patients have difficulty healing wounds, which can affect the grade of diabetic ulcers. The purpose of this study was to determine the relationship between HbA1C levels and the grade of diabetic ulcers according to the Meggitt-Wagner classification in type 2 diabetes mellitus patients at Dr. H. Abdul Moeloek Hospital Bandar Lampung from January-July 2022. This research is a retrospective observational analytic study with a cross-sectional approach. The research sample was 66 patients. The data used is medical records. Selection of the sample using total sampling technique. Statistical analysis was performed using univariate and bivariate analysis. The results of the bivariate analysis using the chi-square test showed a value of p=0.003 (p <0,05) in HbA1C levels and the grade of diabetic ulcers, which means that there is a significant relationship between the variables. There is a significant relationship between HbA1C levels and the grade of diabetic ulcers according to the Meggitt-Wagner classification in type 2 diabetes mellitus patients at Dr. H. Abdul Moeloek Hospital Bandar Lampung from January-July 2022.
Co-Authors Agustyas Tjiptaningrum Betta Kurniawan, Betta Dewi Nur Fiana Dwi Indria Anggraini Dyah Wulan Sumekar Hanna Mutiara, Hanna Hendra Tarigan Sibero Intanri Kurniati Jausal, Annisa Nuraisa Madina Ghassan Nebraska Nurul Utami rahmawati, selvi Rahmayani, Fidha Rekha Nova Iyos, Rekha Nova Risal Wintoko Rizki Hanriko Rodiani, Rodiani Rudiyanto, Waluyo Sagia, Nabilla Alsa Salsabila, Aina Salsabila, Kamila Susianti Susianti Suwandi, Jhons F. Syazili Mustofa Tri Umiana Soleha