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All Journal Medula JK Unila (Jurnal Kedokteran Universitas Lampung)
Hanna Mutiara, Hanna
Bagian Parasitologi, Fakultas Kedokteran, Universitas Lampung
Agriculture, Biological Sciences & Forestry Dentistry Education Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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Hubungan Mutu Pelayanan Dengan Kepuasan Pasien Peserta BPJS di Ruang Rawat Inap Penyakit Dalam RSUD dr. H Abdul Moeloek Mutiara, Hanna; Mayasari, Diana; Fattima, Eliza Techa; Saputri, Chyntia
Jurnal Kedokteran Universitas Lampung Vol 2, No 1 (2018): JK UNILA
Publisher : Fakultas Kedokteran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/jk unila.v2i1.1899

Abstract

Mutu pelayanan rumah sakit sangat penting karena mempengaruhi kepuasan pasien. Mutu pelayanan kesehatan yang baik dapat menimbulkan rasa puas pada diri setiap pasien. Kepuasan pelanggan yang rendah akan berdampak terhadap menurunnya jumlah kunjungan pasien yang akan mempengaruhi profitabilitas fasilitas kesehatan. Tujuan Penelitian untuk mengetahui hubungan mutu pelayanan kesehatan dengan kepuasan pasien BPJS pada ruang rawat inap penyakit dalam di RSUD Dr. H. Abdul Moeloek Provinsi Lampung. Metode penelitian yang digunakan adalah kuantitatif dengan pendekatan cross sectional. Populasi dalam penelitian ini adalah pasien BPJS yang dirawat di ruang rawat inap penyakit dalam Rumah Sakit Umum Daerah Dr. H. Abdul Moeloek Provinsi Lampung dengan jumlah sampel 60 orang menggunakan consecutive sampling. Analisis data menggunakan uji chi square. Hasil penelitian ada hubungan tangible (0,013), reliability (0,027), responsiveness (0,002), assurance (0,000) dan empathy (0,003) terhadap kepuasan pasien di Ruang Rawat Inap Penyakit Dalam RSUD Dr. H. Abdul Moeloek Provinsi Lampung. Kesimpulan, terdapat hubungan yang bermakna antara tangible, reliability, responsiveness, assurance dan empathy terhadap kepuasan pasien di Ruang Rawat Inap Penyakit Dalam RSUD Dr. H. Abdul Moeloek Provinsi Lampung. Kata Kunci : BPJS, Kepuasan Pasien, Mutu Pelayanan
Hubungan Derajat Infeksi Soil Transmitted Helmints (STH) terhadap Peningkatan Jumlah Eosinofil pada Siswa SD Negeri di Kecamatan Jati Agung Kabupaten Lampung Selatan Mutiara, Hanna; Kurniawaty, Evi; Din, Bahesty Cut Nyak
Jurnal Kedokteran Universitas Lampung Vol 3, No 1 (2019): JK Unila
Publisher : Fakultas Kedokteran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/jk unila.v3i1.2212

Abstract

Prevalensi infeksi Soil Transmitted Helminths (STH) di Indonesia masih menunjukkan angka yang tinggi pada siswa sekolah dasar (SD). Prevalensi usia tertinggi infeksi STH merupakan usia 6-12 tahun dimana kondisi ini dapat mempengaruhi intake, digestive, absorpsion, dan metabolisme makanan seseorang yang terinfeksi. Infeksi STH juga dapat menyebabkan peningkatan jumlah eosinofil sebagai suatu respon tubuh dalam melawan infeksi STH. Penelitian ini bertujuan untuk mengetahui hubungan derajat infeksi STH dengan peningkatan jumlah eosinofil pada siswa SD Negeri di kecamatan Jati Agung kabupaten Lampung Selatan. Penelitian ini menggunakan metode observasional analitik dengan pendekatan cross sectional. Sampel pada penelitian ini berjumlah 67 siswa SD Negeri di Kecamatan Jati Agung yang memenuhi kriteria inklusi. Pengambilan sampel dilakukan dengan cara total sampling dan data dianalisis menggunakan uji Kruskal Walis. Infeksi STH sebanyak 56,71% dengan 26,9% infeksi ringan dan 29,8% infeksi sedang. Peningkatan jumlah eosinofil dalam darah pada siswa yang tidak terinfeksi didapatkan nilai rata-rata 16,12; pada siswa yang terinfeksi ringan 40,53; pada siswa yang terinfeksi sedang 54,05. Terdapat hubungan infeksi STH terhadap peningkatan jumlah eosinofil pada siswa SD Negeri di Kecamatan Jati Agung secara statistik (nilai p=0.00). Kata kunci: derajat infeksi, infeksi STH, jumlah eosinofil, siswa
Hubungan Determinan Sosial Kesehatan dengan Infeksi Toksoplasma gondii Jasmine, Almaina Puteri; Mutiara, Hanna; Suwandi, Jhons Fatriyadi; Putri, Giska Tri
Medula Vol 14 No 1 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i1.938

Abstract

Toxoplasma gondii is an obligate intracellular protozoan that causes toxoplasmosis. The high rate of toxoplasmosis infection in the Lampung region reaches 88.23%. Typically, toxoplasmosis presents no symptoms but can pose serious problems for individuals with compromised immune systems or pregnant women. The purpose of this study is to identify the relationship between social health determinant factors such as age, gender, educational level, occupation, and residence address with the incidence of T. gondii infection among patients at Dr. H. Abdul Moeloek Hospital. The aim is to identify individuals at risk of toxoplasmosis infection early so prevention can be done immediately. This study is an analitic quantitative research with a cross-sectional design. The study population consists of patients at Dr. H. Abdul Moeloek Hospital who have been screened for toxoplasmosis from 2017 to 2023, with a sample size of 93 samples. A total of 67 samples were tested positive for toxoplasmosis, while 26 samples tested negative with the sampling technique using total sampling. Data were collected from patients medical records and were analyzed by univariate and bivariate analysis using Chi-square method. The results indicate a relationship between age (p 0.002), gender (p <0.001), and educational level (p <0.001) with the incidence of Toxoplasma gondii infection among patients at Dr. H. Abdul Moeloek Hospital from 2017 to 2023.
Literature Review: Helminthiasis pada Kehamilan Cahyani, Faradhila Azqiah; Septiani, Linda; Mutiara, Hanna; Suwandi, Jhons Fatriyadi
Medula Vol 14 No 2 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i2.944

Abstract

Helminthiasis is a disease caused by intestinal nematode worms that are transmitted through soil orSoil Transmitted Helminth (STH). The types of STH are:Ascaris lumbricoides, Trichuris trichiura, Ancylostoma duodenale, and Necator americanus. Helminthiasis has infected as many as 1.5 billion of the world's population. Helminthiasis is often found in countries with tropical, subtropical climates and countries that are still categorized as poor. Helminthiasis falls into the categoryNeglected Tropical Disease (NTD) which if left untreated can cause health problems. Purpose ofliterature review This provides a review of the epidemiology, clinical manifestations, necessary examinations, and management of helminthiasis, especially in pregnant women. This research uses a literature study method from 2016-2023. The results of this literature study show that clinical manifestations are influenced by the severity or lightness of the infection, gold standardTo find out the incidence of helminthiasis is to do a stool examination, and helminthiasis can be treated by providing care servicesantenatal care. The conclusion is that helminthiasis in pregnant women can affect the condition of the mother and fetus in the womb.
Infeksi Protozoa Usus dan Anemia Sebagai Ancaman Kesehatan Global: Literature Review Rahmah, Nisrina Nur; Mutiara, Hanna; Septiani, Linda; Himayani, Rani
Medula Vol 15 No 1 (2025): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v15i1.1291

Abstract

Intestinal protozoan infections are a global health issue that needs to be monitored due to the high morbidity and mortality rates, particularly in areas with poor hygiene and sanitation. Intestinal protozoan infections are diseases caused by protozoan parasites, which are single-celled eukaryotic microorganisms generally classified under the Kingdom Protista. The most frequently reported intestinal protozoa species responsible for human infections are Blastocystis hominis, Cryptosporidium parvum, and Giardia lamblia. There are two key factors contributing to the occurrence of intestinal protozoan infections: individual and environmental factors. Intestinal protozoan infections are known to cause various harmful consequences, particularly regarding the nutritional status of the affected individuals. As a result, intestinal protozoan infections are often associated with iron deficiency anemia, which can ultimately disrupt growth and development in children and decrease productivity in adults. This study aims to identify the pathways through which intestinal protozoan infections cause iron deficiency anemia. The study method involved a literature review and problem analysis. The results indicate that there are three main pathways through which intestinal protozoan infections lead to iron deficiency anemia: the metabolism of pathogenic microorganisms within the human body, the activation of the immune response to pathogenic microorganisms, and the reduction in micronutrient levels. To prevent these infections, the public is advised to improve personal hygiene, such as regularly washing hands, and to enhance environmental sanitation by treating water through filtration or disinfection.
Manifestasi Klinis Infeksi Parasi Usus pada Anak: Literature Review Nirwan, Qurratul Aina; Mutiara, Hanna; Suharmanto, Suharmanto; Wardani, Dyah Wulan Sumekar Rengganis
Medula Vol 14 No 9 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i9.1394

Abstract

Intestinal parasitic infection is a disease that still neglated, more likely found in developing countries. This infection is caused by a group of intestinal protozoa and worms, generally intestinal nematodes. In children, the STH group is the most common cause of infection. Infection often occurs via the fecal-oral route. Children more often consume infective stages to other age groups due to their poor hygiene behavior.  Intestinal parasitic infections in children can cause high mortality and mobility. This infection causes a decline in health conditions, nutritional absorption, intelligence and productivity. This can simultaneously cause disruption of growth and development in children. These manifestations are related to the virulence of the parasite strain, the number of infective stages consumed, the age of the patient, and the state of the immune system at the time of infection. Apart from that, the manifestations that arise are widespread, asymptomatic to chronic. The manifestions are related to the digestive tract as the target organ of infections. However, manifestations can also be found outside the digestive tract. This is because organisms move to other organs through blood vessels. Manifestations that arise in the digestive tract are usually nausea, vomiting, abdominal pain, constipation, and diarrhea which is sometimes accompanied by blood. Not only that, weakness, fatigue, lethargy, and eating disorders are the manifestation of these infections. This is what causes growth and development disorders in children. Meanwhile, the extraintestinal mainifestations are liver abscess due to amoeba infection, Loeffler syndrome due to Ascaris lumbricoides infection and other manifestations. Usually, the intestinal nematoda infections caused have their own characteristics.
Kandungan Senyawa Aktif Metabolit Sekunder dalam Biolarvasida Annasya, Benazhir Saninah; Mutiara, Hanna; Marcellia, Selvi
Medula Vol 15 No 1 (2025): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v15i1.1252

Abstract

Larvicide is a compound that can be toxic, inhibit growth and development, affect behavior, affect hormones, inhibit feeding, and act as a larval killer. Larvicide is divided into two types, namely chemical larvicide and biolarvicide. Chemical larvicide is the larvicide most widely used by the community because it has a large substance strength. However, the use of chemical larvicide can cause damage, especially insects become resistant to drugs, in addition to causing environmental pollution because synthetic larvicide is difficult to decompose and causes poisoning in humans. The use of chemical larvicide can cause damage, especially insects become resistant to drugs, in addition to causing environmental pollution because synthetic larvicide is difficult to decompose and causes poisoning in humans. Therefore, a substitute for chemical larvicide in the form of biolarvicide is needed. Biolarvicide can act as a larval killer, attractant, antifertility agent (sterilization tool), biocide, and other forms that minimally cause drug resistance in insects. Biolarvicide comes from plant materials containing active compounds of secondary metabolites such as essential oils, saponins, steroids, terpenoids, tannins, alkaloids, flavonoids, and phenolics that can kill mosquito larvae and are obtained by extraction. This article provides a broader explanation of the content of secondary metabolite compounds in biolarvicide so that it can be more effectively used as a larvicide from natural materials. The contents of the article were obtained through searches of several national and international journals through the search keywords: Biolarvicide, secondary metabolites, and active compounds.
Infeksi Cryptosporidium pada Manusia: Patogenesis, Diagnosis dan Terapi Hatimi, Fahmi Ilham; Mutiara, Hanna; Islami, Suryadi; Sukohar, Asep
Medula Vol 15 No 1 (2025): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v15i1.1261

Abstract

Cryptosporidium is a zoonotic protozoan parasite capable of infecting humans and animals, primarily transmitted through contaminated water or food. This infection is a leading cause of moderate to severe diarrhea, particularly in children from low-income regions and immunocompromised individuals, contributing to significant global morbidity and mortality. The pathogenesis of Cryptosporidium involves the invasion of intestinal epithelial cells, resulting in mucosal damage, villous atrophy, and increased intestinal permeability, leading to watery diarrhea. Local inflammatory responses exacerbate symptoms, while immunocompromised individuals often experience chronic infections with serious complications. Diagnosis relies on microscopy, immunofluorescence, and molecular techniques such as PCR, which offer high sensitivity and specificity. Supportive care is the mainstay of treatment, with nitazoxanide being the preferred therapeutic option for selected patients. For immunocompromised individuals, management is more complex and may involve immune restoration therapies, such as antiretroviral treatment for HIV/AIDS patients. However, resistance to conventional treatments remains a significant challenge, necessitating further research into novel therapeutic agents, such as KDU731, which has shown promising efficacy in preliminary studies. This review provides a comprehensive analysis of the pathogenesis, diagnostic methods, and therapeutic strategies for Cryptosporidium infections. Additionally, it highlights the importance of prevention measures, including improved access to clean water and public health education. Enhanced control efforts are crucial to mitigating the global health impact of this infection, particularly among vulnerable populations such as children and immunocompromised individuals.
Analysis of Malathion Insecticide Resistance in Aedes aegypti Mosquitoes Using the CDC Bottle Bioassay Method Kirche, Agnes Angelina; Kurniawan, Betta; Putri, Giska Tri; Mutiara, Hanna
Medula Vol 15 No 1 (2025): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v15i1.1376

Abstract

Dengue is an infectious disease transmitted by the Aedes aegypti mosquito, which breeds rapidly in Indonesia's tropical environment, increasing the risk of spreading this disease. Vector control using malathion insecticide can be effective, but repeated use and inappropriate dosage can cause resistance in mosquitoes which ultimately increases the risk of dengue infection. CDC Bottle Bioassay is a test method for evaluating mosquito resistance to insecticides with a standardized procedure and is carried out using bottles containing insecticides with different diagnostic doses. Research using this method shows that Aedes aegypti mosquitoes in various locations show resistance to malathion at certain doses and tolerance at other doses. Several studies have also shown that mosquitoes exposed to malathion show categories of resistance or tolerance based on the mortality rate recorded during the test. Malathion, which is a class of organophosphorus insecticides, works by irreversibly binding to acetylcholinesterase and effectively kills mosquitoes, but repeated use can trigger resistance. Factors influencing resistance include biological factors such as migration, operational factors such as insecticide dosage and application, as well as genetic factors associated with the resistant allele. If mosquitoes carrying resistant alleles move or interbreed, this can increase the resistance status in an area, which is seen in Aedes aegypti populations in several regions of the world.
Co-Authors Annasya, Benazhir Saninah Asep Sukohar Betta Kurniawan, Betta Cahyani, Faradhila Azqiah Din, Bahesty Cut Nyak Dyah Wulan Sumekar Rengganis Wardani Eliza Techa Fattima, Eliza Techa Giska Tri Putri Hatimi, Fahmi Ilham Jasmine, Almaina Puteri Jhons Fatriyadi Suwandi Kirche, Agnes Angelina Kurniawaty, Evi Marcellia, Selvi Mayasari, Diana Nirwan, Qurratul Aina Rahmah, Nisrina Nur Rani Himayani Saputri, Chyntia Septiani, Linda Suharmanto Suryadi Islami