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Utilization of Stem Bark and Leaves of Kluwih (Artocarpus Altilis Park) as an Anti-Mosquito Repellent: A Case Study of Total Mosquito Mortality (Anopheles Sp) Kurniawan, Betta; Puspita, Laila; Kurnia, Yogi; Husna, Ismalia; Rahmat, Ali; Umam, Rofiqul; Andriana, Bibin B.; Jermsittiparsert, Kittisak
Indonesian Journal of Science and Technology Vol 5, No 3 (2020): IJOST: VOLUME 5, ISSUE 3, 2020
Publisher : Universitas Pendidikan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.17509/ijost.v5i3.25370

Abstract

The purpose of this study was to demonstrate an alternative solution as an insecticide from Indonesian natural ingredients. We investigated the potential use of Artocarpus altilis park (known as kluwih plants in Indonesia) for an anti-mosquito repellent because it contains flavonoids and saponins. The use of this type of insecticide is harmless, inexpensive, and largely available in Indonesia. In the experiment, we extracted bark and leaves of kluwih to obtain insecticidal material to repel Anopheles sp. To ensure the precise extraction and insecticidial effect, the experiments were conducted four times with three repetitions. For each experiment, we used 8.4 mL with the concentrations of 20, 30, and 40% of flavonoid. The results showed that the higher the concentrations of bark and leaf extracts of Artocarpus altilis park the higher the mortality rate of Anopheles sp is.
Hubungan Keaktifan Berorganisasi dengan Manajemen Waktu dan Indeks Prestasi Kumulatif pada Mahasiswa Angkatan tahun 2013 di Fakultas Kedokteran Universitas Lampung Hendra Effendi; Rika Lisiswanti; Merry Indah Sari; Betta Kurniawan
Medula Vol 10 No 1 (2020): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v10i1.11

Abstract

Students have role as an agents of change by participating in organization without neglecting their academic achievement. Student’s academic achievement is measured by Grade Point Average (GPA). Students need a good skill to manage their time between academic activities, and organizational activities. We conduct research to determine the relationship of organizational participation with level of time management and GPA of students batch 2013 in Medical Faculy of Lampung University.This research method is a comparative and correlative analytic observational study with a cross-sectional approac. This research was conducted in June 2016 at the Faculty of Medicine, University of Lampung. The sample was selected by consecutive sampling and obtained 40 respondents for each student who was active and not active in organizing. The hypothesis test used was the Chi-square comparative test and the Gamma correlative test. The level of time management based on organizational participation showed no significant difference. There was a significant difference in the GPA based on the activeness of organizing with a better GPA on students who wereactive in organization. There was no relationship between the level of time management with the level of GPA.
Karakteristik Fisik, Kimia, dan Biologi Tempat Perindukan Potensial Nyamuk Anopheles sp. di Wilayah Kerja Puskesmas Hanura Septilia Sugiarti; Riyan Wahyudo; Betta Kurniawan; Jhons Fatriyadi Suwandi
Medula Vol 10 No 2 (2020): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v10i2.66

Abstract

Malaria is an infectious disease transmitted through mosquitoes and has become a health problem both in the world and Indonesia especially in Lampung. The population of the malaria vector is strongly influenced by the location of the breeding place. This study will examine the characteristics of breeding place of Anopheles sp as the malaria vector. This was an observational descriptive study conducted in the work area of Puskesmas Hanura Kabupaten Pesawaran. The physical characteristics has done by measuring temperature and water depth, the chemical characteristics by measuring pH and water salinity, and the biological characteristics by looking at organisms found at the sampling site. The breeding places are damaged boat, lagun, ditch, rice fields and abandoned ponds. The characteristics of the breeding palces are water temperature 29.5-32.4°C, water depth 10.1-28.6 cm, pH 5-6.6, salinity 0-9.3. Predators found in the breeding place are Aplocheilus panchax (tin head fish), Gambusia affinis (Cere Fish), Culex sp. (larvae stages), Aedes sp. (larvae stages), and water plants Ocsillatoria sp. (alga), Spirogyra (alga). Physical, chemical, and biological characteristics of Anopheles sp. breeding place in Puskesmas Hanura working area are optimum characteristics for Anopheles sp. breeding.
The Relation Between Emotional Quotient and Self-Directed Learning Readiness of Students in Medical Faculty of Lampung University Indah Anita Dewi; Dwita Oktaria; Betta Kurniawan
Medula Vol 9 No 4 (2020): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v9i4.220

Abstract

Learning in medical faculties that use the method of problem-based learning (PBL) requires students to be able to study independently (SDL). Even though they have previously been exposed to SDL, students still do not have the readiness to study independently so that they cannot implement SDL well. Emotional quotient is the ability to manage the emotions of self and others. Students who have emotionally quotient will have good self-control so that there is greater potential for implementing independent learning. Emotional quotient is closely related to the readiness of individual independent learning. The higher the emotional quotient and self-directed learning readiness, the easier it is for individuals to be able to apply independent learning (SDL). This study aims to determine the relationship of emotional quotient with self-directed learning readiness of students in Medical Faculty of Lampung University. Data retrieval in this study using questionnaires tool that has been tested for validity and reliability. The sample uses a stratified random sampling technique from FK Unila medical students class of 2016, 2017, 2018 and 2019 as many as 255 samples. Univariate analysis showed most respondents have a high emotional quotient 83,9%, a moderate emotional quotient 16,1% and no respondents have a low emotional quotient. Respondents with a high self-directed learning readiness were 78,4 %, a moderate self-directed learning readiness 21,6% and no respondents have a low self-directed learning readiness. Bivariate analysis with chi-square test obtained p-value <0.05 and there is a significant relationship between emotional quotient and self-directed learning readiness of students in Medical Faculty of Lampung University.
Efektivitas Dari Tanaman Zodia (Evodia Suaveolens) Sebagai Insektisida Nabati Nyamuk Aedes aegypti Penyebab Demam Berdarah Anniza Agustina; Betta Kurniawan; M. Yusran
Medula Vol 9 No 2 (2019): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v9i2.282

Abstract

Dengue Hemorrhagic Fever (DHF) is a problem of one infectious disease in the community. Dengue virus infection through Aedes aegypti mosquito bites to humans as a vector. Eradication of vectors using insecticides must be environmentally friendly and safe for the ecosystem. Vegetable insecticide was chosen because it is easy to obtain and friendly to the environment. Zodia plants have been widely used by the people, especially the people of Papua as an anti-mosquito. Because of the content of evodiamine, rutaecarpine, and linalool, a-pinene is very effective as a mosquito repellent. Three ways of working plant-based insecticides work, namely: contact poison, gas poison and stomach poison. Research by calculating the average number of mosquitoes - the number of mosquitoes perched on the probandus arm with a concentration of 5%, 10%, 15%, 20%, 25%, 30% proves that the concentration of 25% has a longer protective power of 4 hours with an average of an average of 91%. Other studies say that the concentration of Zodia leaves can last five hours with a concentration of 60% even though it has only 48% protective power. The addition of a fragrant aroma that is fixative can increase protective power. This zodia plant contains linalool (46%) and a-pinene (13.26%). Linalool in zodia leaf essential oils have active ingredients such as evodiamine and rutaceacarpine which have a bitter taste and distinctive aroma.
THE EFFECTIVENESS OF BINAHONG LEAF EXTRACT (Anredera cordifolia (Ten.) Steenis) AND MEFENAMIC ACID AS ANTI INFLAMATION TO WHITE MALE RAT INDUCED BY KARAGENIN Betta Kurniawan; Novita Carolia; Abigail Pheilia
JUKE Unila Vol 4, No 8 (2014)
Publisher : Fakultas Kedokteran Universitas Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (136.853 KB)

Abstract

Background: Binahong (Anredera cordifolia (Ten.) Steenis) has been used by people as a herb medicine to threat wound, diabetes, ans choleterol. The examination of effectiveness binahong leaf exctract  on rat food edema of Sprague Dawley strain induced with 1% of karagenin. Method: The study method was modification of Winter (1962). This study was an experimental design with pre and post test control group design. The Rats were divided into five treatment groups (negative control with distilled water provision, positive control with the administration of mefenamic acid, and three groups treated with the extract dose binahong 25.2 mg/200 g BW, 50.4 mg/200 g BW, and 100.8 mg/200 g BW). Result: This study showed binahong leaf extract has anti-inflammatory power on the positive control group, the extract dose binahong were 25.2 mg/200 g BW, 50.4 mg/200 g BW, and 100.8 mg/200 g BW respectively for 11.00 %, 5.17%, 10.12%, and 1.92%. Conclusion: The highest dose of binahong extract as anti-inflammatory effects in this study were 50.4 mg/200 g BW. [JuKe Unila 2014; 4(8):151-157]
PLASMODIUM KNOWLESI Betta Kurniawan; Jhons Fatriyadi Suwandi; Syazili Mustofa; Sri Janahtul Hayati
JURNAL KEDOKTERAN DAN KESEHATAN Vol 7, No 2 (2020)
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/JKK.V7I1.9657

Abstract

Malaria is a disease which caused by a parasite member of the species  of genus Plasmodium. Plasmodium knowlesiis a parasite which found in long-tailed macaques and was firstdiscovered in 1930 from the Macaca fascicularisspeciment from Singapore. In 2004 there was a reported P. knowlesiinfection in humans in Sarawak, Borneo Malaysia and this finding made P. falciparumas the fifth malaria parasite which infect humans. Plasmodium knowlesican sustain its erytrocytic cycle within 24 hours so it can caused a higher infection proggressifity than another parasites. Plasmodium knowlesi’s switch transmission from macaques to human  involve some factors, both demographically, environmentaly, and individual behavior.
Identification of Plasmodium Falciparum Merozoit Surface Protein-1 (PFMSP-1) Gene From Malaria Patients in Hanura Area, Lampung, Indonesia Ade Triajayanti; Jhons Fatriyadi Suwandi; Betta Kurniawan; Nurul Utami
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 3 No. 4 (2019): Bioscientia Medicina: Journal of Biomedicine and Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bsm.v3i4.97

Abstract

Introduction: Malaria is a major health problem not only in Indonesia, but also the world. Incidence of anti malarial drug resistance has been found, and one of the possible cause is genetic factors. The changes that occur in the Plasmodium falciparum gene cause genetic variations that lead to resistance for treatment. There is a gene with high polymorphism that can be used as a gene marker of genetic variation in Plasmodium falciparum. Aim of Study: This study aim to identification of plasmodium falciparum merozoit surface protein-1 (PFMSP-1) gene from malaria patients in Puskesmas Hanura, Pesawaran, Lampung. Methods: Descriptive method with morbidity survey approach is used in this study. There are total 23 biological material stored that had been taken in 2016 from malaria patient in Puskesmas Hanura, Pesawaran, Lampung, by consecutive sampling. Identification of genetic variance of the Plasmodium falciparum gene was performed by nested PCR at Medical Faculty Biomolecular Laboratory of Lampung University. The results of this study were processed using a computer software. Results: There are 23 samples that amplified following nested PCR for Plasmodium falciparum Merozoit Surface Protein-1 (PFMSP-1) gene target. In all samples studied, there are PFMSP-1 gene with six variations base pair length range from 200 to 2000 bp. Conclusions: this study has successfully amplified PFMSP-1 gene from individual’s blood sample infected by Malaria in Puskesmas Hanura work region, Pesawaran, Lampung.
Uji Diagnostik Kecacingan antara Pemeriksaan Feses dan Pemeriksaan Kotoran Kuku pada Siswa SDN 1 Krawangsari Kecamatan Natar Lampung Selatan Betta Kurniawan; Muhammad Ricky Ramadhian; Nurul Sahana Rahmadhini
Jurnal Kedokteran Universitas Lampung Vol 2, No 1 (2018): JK UNILA
Publisher : Fakultas Kedokteran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/jk unila.v2i1.1907

Abstract

Kecacingan terjadi diawali dengan tertelannya telur atau masuknya larva yang infektif ke dalam kulit. Beberapa faktor yang dapat mempengaruhi tertelannya telur cacing berkaitan dengan higinitas yaitu kuku yang panjang dan tidak terawat. Pemeriksaan kotoran kuku akan dibandingkan dengan pemeriksaan gold standard untuk mengetahui nilai sensitivitas pemeriksaan kotoran kuku. Penelitian ini bersifat analitik komparatif dengan pendekatan cross sectional. Subjek penelitian terdiri dari 58 siswa dengan mengambil sampel feses dan kotoran kuku. Pemeriksaan feses dilakukan dengan metode apung dan pemeriksaan kuku dilakukan dengan metode sedimentasi. Angka kejadian kecacingan menggunakan bahan pemeriksaan feses sebesar 56% dan angka kejadian kecacingan menggunakan bahan pemeriksaan kotoran kuku sebesar 24,1%. Berdasarkan uji Mc-nemar didapatkan nilai p sebesar 0,02 yang artinya ada perbedaan yang bermakna antara pemeriksaan kotoran kuku dan pemeriksaan feses. Nilai sensitivitas dan spesifisitas sebesar 18,2% dan 68%. Nilai duga positif sebesar 42,8% dan nilai duga negatif sebesar 43,1%. Hasil pemeriksaan kuku dengan pemeriksan feses secara statistik terdapat perbedaan. Nilai sensitivitas didapatkan rendah, sehingga pemeriksaan kotoran kuku tidak mampu disetarakan dengan pemeriksaan feses.Kata Kunci : Diagnosis, kecacingan, pemeriksaan feses, pemeriksaan kuku
Identification of Plasmodium Falciparum Merozoit Surface Protein-1 (PFMSP-1) Gene From Malaria Patients in Hanura Area, Lampung, Indonesia Ade Triajayanti; Jhons Fatriyadi Suwandi; Betta Kurniawan; Nurul Utami
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 3 No. 4 (2019): Bioscientia Medicina: Journal of Biomedicine and Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bsm.v3i4.97

Abstract

Introduction: Malaria is a major health problem not only in Indonesia, but also the world. Incidence of anti malarial drug resistance has been found, and one of the possible cause is genetic factors. The changes that occur in the Plasmodium falciparum gene cause genetic variations that lead to resistance for treatment. There is a gene with high polymorphism that can be used as a gene marker of genetic variation in Plasmodium falciparum. Aim of Study: This study aim to identification of plasmodium falciparum merozoit surface protein-1 (PFMSP-1) gene from malaria patients in Puskesmas Hanura, Pesawaran, Lampung. Methods: Descriptive method with morbidity survey approach is used in this study. There are total 23 biological material stored that had been taken in 2016 from malaria patient in Puskesmas Hanura, Pesawaran, Lampung, by consecutive sampling. Identification of genetic variance of the Plasmodium falciparum gene was performed by nested PCR at Medical Faculty Biomolecular Laboratory of Lampung University. The results of this study were processed using a computer software. Results: There are 23 samples that amplified following nested PCR for Plasmodium falciparum Merozoit Surface Protein-1 (PFMSP-1) gene target. In all samples studied, there are PFMSP-1 gene with six variations base pair length range from 200 to 2000 bp. Conclusions: this study has successfully amplified PFMSP-1 gene from individual’s blood sample infected by Malaria in Puskesmas Hanura work region, Pesawaran, Lampung.