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Suryadi Islami
Fakultas Kedokteran, Universitas Lampung
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Kejadian Drug Induced Renal Disease pada Pasien Pediatri Ervina Damayanti; Afriyani Afriyani; Femmy Andrifianie; Suryadi Islami; Ergidona Nurizqi; Syiffatulhaya Syiffatulhaya; Winda Winda; Luhut Uji Arto Naenggolan; Natasya Karren Zeta
Jurnal Kedokteran Universitas Lampung Vol 7, No 1 (2023): JURNAL KEDOKTERAN UNIVERSITAS LAMPUNG
Publisher : Fakultas Kedokteran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/jkunila7137-42

Abstract

Drug induced renal disease adalah penyakit ginjal yang diinduksi oleh obat – obatan. Beberapa obat-obatan dapat menyebabkan gagal ginjal akut, obstruksi intrarenal, nefritis interstitial, sindrom nefrotik serta gangguan kesetimbangan asam basa dan cairan elektrolit. Obat-obatan seperti antimikroba, obat antiinflamasi non steroid (OAINS) dan agen kemoterapi dapat menginduksi terjadinya gagal ginjal pada anak – anak. Artikel ini akan membahas lebih lanjut terkait informasi mengenai kejadian dan mekanisme drug-induced renal disease yang penting diketahui untuk mencegah kejadian gagal ginjal pada anak - anak. Penelusuran artikel ilmiah dilakukan melalui database elektronik dari berbagai terbitan jurnal nasional maupun internasional seperti PubMed/MEDLINE, EMBASE, EBSCO, Scopus, Cochrane Central Register of Controlled Trials, dan database pencarian Google Scholardengan kata kunci seperti obat induksi, gagal ginjal, nefrotoksisitas, dan anak-anak. Sumber data yang digunakan adalah hasil publikasi dari tahun 2013 sampai 2022.Berdasarkan hasil reviu dari 25 artikel, didapatkan bahwa kejadian gagal ginjal pada anak dapat disebabkan oleh beberapa obat-obatan seperti antimikroba (aminoglikosida dan amfoterisin B), obat antiinflamasi non steroid (OAINS) dan agen kemoterapi (ifosfamid, sisplatin dan metotreksat). Kerusakan ginjal yang diinduksi oleh obat biasanya melibatkan sel-sel tubular ginjal karena sebagian besar berada pada kondisi hipoksia untuk mengatasi kebutuhan metabolisme yang tinggi yang diperlukan dalam proses reabsorpsi elektrolit dan mengendalikan hidrasi.Kata Kunci: gagal ginjal, nefrotoksisitas, induksi obat, pediatri
PELATIHAN PEMBUATAN NUGGET IKAN NILA SEBAGAI UPAYA PENINGKATAN POTENSI DESA TUGU MULYA, LAMPUNG BARAT Suryadi Islami; Ervina Damayanti; Sofyan Musyabiq Wijaya; Selvi Marcellia; Linda Septiani
Dharma: Jurnal Pengabdian Masyarakat Vol 4, No 1 (2023): Mei
Publisher : Universitas Pembangunan Nasional "Veteran" Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31315/dlppm.v4i1.9452

Abstract

Desa Tugu Mulya merupakan salah satu desa di Kecamatan Kebun Tebu, Kabupaten Lampung Barat, Provinsi Lampung. Desa ini memiliki potensi yang perlu diperhatikan yaitu masyarakatnya memiliki budidaya ikan nila yang biasanya hanya dijual segar dan diolah sederhana. Di samping itu, konsumsi protein hewani di Provinsi Lampung masih rendah padahal hal ini sangat penting dalam meningkatkan kualitas kesehatan masyarakat. Pengabdian ini dilaksanakan dengan tujuan untuk melatih masyarakat membuat nugget ikan nila sebagai upaya peningkatan potensi desa. Pelatihan dilaksanakan dengan pematerian terlebih dahulu dan dilanjutkan dengan praktik pembuatan secara langsung oleh peserta. Hasil yang diperoleh yaitu peserta mengetahui dan memahami manfaat ikan nila sebagai sumber protein hewani, pentingnya konsumsi ikan nila dan pengolahan ikan nila menjadi nugget yang memiliki masa simpan lebih lama dan nilai jual lebih tinggi. Selain itu, pelatihan ini dapat memberikan kemampuan peserta dalam membuat nugget ikan nila secara mandiri.
PENERAPAN SISTEM DIGITAL MARKETING PADA PENJUALAN PRODUK HASIL OLAHAN KWT (KELOMPOK WANITA TANI) PEKON MUARA BARU Suryadi Islami; arby tamaila; Andika S.D.R.; Adelia Farisa; Suci Nurhaliza; Daudea Kirana Sari; Triavina Khairunisa; Mighuel A.S.N.
Jurnal Pengabdian Sosial Indonesia Vol 2, No 2 (2022): Jurnal Pengabdian Sosial Indonesia (JPSI)
Publisher : Universitas Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (166.387 KB)

Abstract

Pekon Muara Baru merupakan salah satu pekon yang ada di Kecamatan Kebun Tebu Kabupaten Lampung Barat. Di Pekon Muara Baru ini terdapat Kelompok Wanita Tani (KWT) yang mempunyai kegiatan rutin seperti menanam sayuran. Selain menanam sayuran Kelompok Wanita Tani (KWT) ini juga memproduksi makanan, seperti keripik ubi, keripik pare, kacang asin manis pedas, keripik tempe, dll. dan produk tersebut juga dijual oleh Kelompok Wanita Tani (KWT), namun proses pemasaran yang dilakukan oleh Kelompok Wanita Tani (KWT) ini hanya dengan menitipkan produk tersebut diwarung-warung yang ada disekitar Pekon Muara Baru dan mempromosikannya melalui mulut ke mulu. Oleh karena itu, dilaksanakan penyuluhan mengenai pengenalan dan pelatihan penerapan digital marketing oleh mahasiswa Kuliah Kerja Nyata (KKN) agar Kelompok Wanita Tani (KWT) dapat memasarkan produknya melalui media digital.Kata kunci: penyuluhan, pengenalan, pelatihan, digital marketing.Doi: http://dx.doi.org/10.23960/JIPS/v2i1.97-103
Status Gizi Berhubungan dengan Kadar Hb pada Anak Sekolah Dasar Nisa Karima; Khairun Nisa Berawi; Suryadi Islami
Jurnal Penelitian Perawat Profesional Vol 6 No 2 (2024): April 2024, Jurnal Penelitian Perawat Profesional
Publisher : Global Health Science Group

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/jppp.v6i2.2316

Abstract

Anemia merupakan penurunan kadar hemoglobin yang mengakibatkan tidak terpenuhinya kebutuhan fisiologis hemoglobin. Salah satu faktor penurunan kadar hemoglobin adalah status gizi. Tujuan penelitian ini mengetahui hubungan status gizi dengan kadar Hb pada anak sekolah. Penelitian ini adalah penelitian deskriptif analitik dengan metode cross sectional. Teknik pengambilan sampel diambil secara cluster randon sampling. Penelitian menggunakan data IMT/Umur dan hasil hemoglobin dilakukan menggunakan hematology analyzer. Data dianalisis menggunakan analisis univariat dan bivariat menggunakan uji Chi-Square. Hasil penelitian menunjukkan bahwa ada hubungan antara status gizi dengan kadar Hb anak sekolah (p=0,029).
EDUKASI PENCEGAHAN STUNTING DI PEKON PAMPANGAN, LAMPUNG BARAT Afriyani; Ervina Damayanti; Suryadi Islami; M. Rifqi Efendi; Mesa Sukmadani Rusdi
Jurnal Pengabdian Multidisiplin Indonesia (JUPEMI) Vol. 1 No. 1 (2023): Juni
Publisher : Merwinspy Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.69820/jupemi.v1i1.21

Abstract

Stunting adalah kondisi gagal tumbuh pada anak-anak yang ditandai dengan pertumbuhan dan perkembangan fisik yang terhambat. Walaupun hasil Studi Status Gizi Indonesia (SSGI) 2021 telah menunjukkan penurunan angka stunting nasional dari 27,7% pada tahun 2019 menjadi 24,4% pada tahun 2021. Namun, angka tersebut masih dikategorikan tinggi menurut WHO (>20%). Penyuluhan ini bertujuan untuk memberikan edukasi kepada masyarakat khususnya kader Posyandu, ibu hamil, ibu menyusui dan ibu yang memiliki balita di Pekon Pampangan, Kecamtan Sekincau, Kabupaten Lampung Barat terhadap pencegahan stunting. Metode pengabdian ini adalah metode pemberdayaan masyarakat partisipatif, yaitu metode yang menekankan keterlibatan masyarakat pada rangkaian kegiatan. Kegiatan penyuluhan pencegahan stunting berjalan dengan lancar dan sukses. Evaluasi menunjukkan adanya peningkatan pengetahuan peserta. Diharapkan bahwa penyuluhan ini akan meningkatkan kesadaran masyarakat mengenai tumbuh kembang anak, sehingga dapat mencegah terjadinya stunting dan menurunkan persentase stunting di Indonesia, terutama di Pekon Pampangan, Kecamatan Sekincau, Kabupaten Lampung Barat.
Analisis Fear of Failure (FoF) pada Mahasiswa Kedokteran Vidini Caya, Tazkia; Oktafany, Oktafany; Islami, Suryadi
Medula Vol 14 No 3 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i2.988

Abstract

Fear of failure is a person's response to the failure they experience and anticipation to avoid the bad consequences of that failure. Fear of failure can have both positive and negative impacts. Anyone can experience fear of failure, including medical students as students who are pursuing an education full of challenges and responsibilities. Medical students take a longer period of education and bear greater demands and roles than other students. To determine the level of fear of failure, the researchers used a research instrument in the form of a questionnaire, namely the Performance Failure Appraisal Inventory (PFAI). Universally, medical education educates students with the academic achievements that need to be achieved to obtain a license and guarantee a bright future. Without academic achievement and good achievement, degrees and job opportunities, even continuing education will not be easy to obtain. The level of fear of failure varies based on gender, academic year, Grade Point Average (GPA), interest in medical science, etc. Fear of failure shows a negative relationship with medical student learning achievement. Thus, fear of failure in medical students needs to be a concern for educational institutions in understanding student behavior and shaping the scope of teaching and providing counseling that can help medical students overcome the fear of failure.
Teknik Penyuntingan Gen Clustered Regularly Interspaced Short Palindromic Repeats-Cas9 (CRISPR-Cas9) sebagai Terapi Penyakit Genetik Bawaan: Ulasan Literatur Islami, Suryadi; Haq, Rais Amaral; Arianto, Nayla Nadhifa; Sabina, Diana Larisa
Medula Vol 14 No 2 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i2.999

Abstract

The development of therapy for inherited genetic diseases using CRISPR-Cas9 technology has shown significant progress. This article discusses the history and working principles of CRISPR-Cas9, highlighting its applications in the therapy of inherited genetic diseases. Current research focuses include diseases such as cystic fibrosis, thalassemia, and Duchenne muscular dystrophy. Genetic therapy with CRISPR-Cas9 involves editing specific genes to correct disease-causing mutations, opening up opportunities for more effective treatments. Regarding the use of this technique, there are various difficulties, such as potential off-target effects, ethical issues, and long-term safety. However, efforts continue to be made to improve the specificity and accuracy of CRISPR-Cas9 so that the development of effective delivery methods and improving safety has become a major focus of research. Potentially, CRISPR-Cas9 could become a more specific and personalized genetic therapy, opening up opportunities to treat genetic diseases at the molecular level and providing alternative therapies for diseases that were previously difficult to treat. In addition, this technology has the potential for early prevention of genetic diseases and the development of more affordable gene therapies. Interdisciplinary collaboration is key in optimizing the potential of CRISPR-Cas9 to ensure the development of genetic disease therapies that are ethical and beneficial to human health in the future.
Faktor Risiko yang Dapat Diubah pada Demensia Lansia: Ulasan Literatur Naratif Singkat Hatimi, Fahmi Ilham; Hardiansyah, Ridwan; Islami, Suryadi
Medula Vol 15 No 1 (2025): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v15i1.1182

Abstract

The gradual neurological disease known as dementia causes a substantial reduction in cognitive function, which impairs an older person's capacity to carry out everyday tasks on their own. Dementia is a serious worldwide health concern since its prevalence rises with age. Through a narrative literature review, this study seeks to uncover modifiable risk factors for dementia in the elderly. Utilizing the terms "dementia risk factors," "factors of dementia," and "dementia in elderly," information was obtained from databases including Google Scholar, Garuda, and NCBI. The results show that reducing alcohol intake, quitting smoking, managing diabetes mellitus, and engaging in regular physical activity are all effective ways to avoid dementia. Increased cerebral blood flow from exercise supports cognitive function and slows the progression of dementia. Quitting smoking and drinking less alcohol reduces oxidative stress, inflammation, and neurotoxic damage—all of which hasten the onset of neurodegenerative diseases. Controlling diabetes helps avoid hypoxia and vascular damage, both of which can worsen cognitive impairment. These lifestyle changes not only lessen the risk of dementia but also greatly lessen the financial, social, and emotional strain on people, families, and communities. This article highlights the value of early intervention through lifestyle modifications and how it can enhance older people's overall quality of life. It offers practical advice on how to lessen the effects of dementia, one of the most important health issues of our time.
Infeksi Cryptosporidium pada Manusia: Patogenesis, Diagnosis dan Terapi Hatimi, Fahmi Ilham; Mutiara, Hanna; Islami, Suryadi; Sukohar, Asep
Medula Vol 15 No 1 (2025): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v15i1.1261

Abstract

Cryptosporidium is a zoonotic protozoan parasite capable of infecting humans and animals, primarily transmitted through contaminated water or food. This infection is a leading cause of moderate to severe diarrhea, particularly in children from low-income regions and immunocompromised individuals, contributing to significant global morbidity and mortality. The pathogenesis of Cryptosporidium involves the invasion of intestinal epithelial cells, resulting in mucosal damage, villous atrophy, and increased intestinal permeability, leading to watery diarrhea. Local inflammatory responses exacerbate symptoms, while immunocompromised individuals often experience chronic infections with serious complications. Diagnosis relies on microscopy, immunofluorescence, and molecular techniques such as PCR, which offer high sensitivity and specificity. Supportive care is the mainstay of treatment, with nitazoxanide being the preferred therapeutic option for selected patients. For immunocompromised individuals, management is more complex and may involve immune restoration therapies, such as antiretroviral treatment for HIV/AIDS patients. However, resistance to conventional treatments remains a significant challenge, necessitating further research into novel therapeutic agents, such as KDU731, which has shown promising efficacy in preliminary studies. This review provides a comprehensive analysis of the pathogenesis, diagnostic methods, and therapeutic strategies for Cryptosporidium infections. Additionally, it highlights the importance of prevention measures, including improved access to clean water and public health education. Enhanced control efforts are crucial to mitigating the global health impact of this infection, particularly among vulnerable populations such as children and immunocompromised individuals.
Aktivitas Pupisida Ekstrak Etanol Daun Belimbing Wuluh (Averrhoa bilimbi L.) terhadap Kematian Pupa Aedes aegypti L. Islami, Suryadi; Hardiansyah, Ridwan; Afriyani; Hafizh, Ahmad Fauzan; Temun, Jedo Muchamad Tias
Bioscientist : Jurnal Ilmiah Biologi Vol. 13 No. 3 (2025): September
Publisher : Department of Biology Education, FSTT, Mandalika University of Education, Indonesia.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33394/bioscientist.v13i3.15389

Abstract

This study aimed to determine the pupicidal activity of ethanol extract from bilimbi ( Averrhoa bilimbi L.) leaves against Ae. aegypti pupal mortality. A true experimental design was employed to evaluate the toxicity of various ethanol extract concentrations against pupae over treatment periods of 24 and 48 hours. Mortality rates were recorded and calculated using the WHO mortality formula, and lethal concentrations (LC50 and LC90) were determined via probit analysis to identify concentrations causing 50% and 90% pupal mortality. The results showed that the ethanol extract exhibited dose-dependent pupicidal activity, with the highest mortality observed at 4% concentration, achieving 97.33% mortality after 48 hours. The LC50 values were 2.378% at 24 hours and 1.425% at 48 hours, indicating an increased effectiveness over time. The findings suggest that the ethanol extract of bilimbi leaves has potential as a natural pupicide, offering an eco-friendly alternative for controlling Ae. aegypti populations. Further studies are needed to optimize formulation and field application for sustainable mosquito vector management.
Co-Authors Adelia Farisa Adisti, Fransiska Afriyani Afriyani Afriyani, Afriyani Afriyani, Afriyani ani Ambarwati, Endah Andika S.D.R. Andrifianie, Femmy Arafah, Aisyah Putri arby tamaila Arianto, Nayla Nadhifa Arif, Ahmad Fauzan Arif, Muhammad Farhan Asep Sukohar Atmaja, Ghozi Purna Bachtiar, Nabylly Aghna Callista, Eugenia Centya Cheirini Damayanti, Ervina Daudea Kirana Sari Dita Noviyanda Saerulloh Djamilu, Berneta Rendiana Dwi, Farah Ergidona Nurizqi Ervina Damayanti Ervina Damayanti Ervina Damayanti Ety Apriliana Ety Apriliana Evy Afriyani Farhana, Lubna Fauzi Ahmad Muda Febriana, Triana Femmy Andrifianie Fitria Saftarina Habib, Farid Alif Hafizh, Ahmad Fauzan Hanna Mutiara, Hanna Haq, Rais Amaral Hardiansyah, Ridwan Hatimi, Fahmi Ilham Ihsanti Dwi Rahayu Ikhsan, Muhammad Ali Indri Windarti Irma Nur Humaida Januaristy, Gracia Rescuefa Jausal, Anisa Nuraisa Jhons Fatriyadi Suwandi Khairun Nisa Kirana, Shela Sandra Laksana, Bayu Larasati, Ratri Mauluti Linda Septiani Luhut Uji Arto Naenggolan M. Rifqi Efendi Magistra, Muhammad Akbar Marcellia, Selvi Mesa Sukmadani Rusdi Mighuel A.S.N. Muhammad Fitra Wardhana Sayoeti Muhammad Maulana Muhammad Ricky Ramadhian Nadly, Alan Arindo Natasya Karren Zeta Nisa Karima Nugraha, Dian Sastra Oktafany, Oktafany Panjaitan, Annisa Tamara Pardilawati, Citra Yuliyanda Putri Handayani Putri, Eka Meilinda Putri, Reny Arienta Qonita, Adzrok Ramadhina, Farrasyifa Ramdini, Dwi Aulia Rika Lisiswanti Rizki Hanriko Rizki Nisfi Ramdhini Rosa, Emantis Rossa, Putri Emylia Rudiyanto, Waluyo Sabina, Diana Larisa Sari, Dewi Hambar Selvi Marcellia Septiani, Linda Sitanggang, Grety Thessalonica Sofyan Musyabiq Wijaya Sri Suciati Ningsih Suci Nurhaliza Suri, Nurma Susianti Susianti, Susianti Syiffatulhaya Syiffatulhaya Temun, Jedo Muchamad Tias Triavina Khairunisa Vanadis, Zifa Aisha Vestinaliyou, Nanda Vidini Caya, Tazkia Wijaya, Ardia Syifa Winda Winda Yustina Yustina