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All Journal PROSIDING SEMINAR NASIONAL Jurnal Riset Kesehatan Pharmaqueous Jurnal Pengabdian Pancasila (JPP) Innovative: Journal Of Social Science Research Indonesian Journal of Innovation Multidisipliner Research Jurnal Laboratorium Khatulistiwa Jurnal Kesehatan Indonesian Journal of Innovation Multidisipliner Research
Dini Puspodewi
Universitas Al-Irsyad Cilacap
Religion Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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Socialization of Prevention of Escherichia coli Bacterial Contamination in Well Water in Sidanegara Village as a Stunting Countermeasure Imam Agus Faizal; Dini Puspodewi; Frisca Dewi Yunadi; Ira Pangesti; Mika Tri Kumala Swandari
Jurnal Pengabdian Pancasila (JPP) Vol. 3 No. 2 (2024): June 2024
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/jpp.v3i2.9967

Abstract

Human health can be directly affected by water quality if E. Coli bacteria are found. Most residents of Cilacap Regency get their drinking water from wells, cooking, washing household appliances, and poor sanitation behavior. This method of community service in health counseling is divided into several stages of implementation. These stages include pre-service surveys and counseling. The results of the pre-test with the theme Identification of E. coli Bacteria Contamination as a Stunting Response were obtained with an average cadre knowledge score of 86. Meanwhile, the average score of the post-test questionnaire was 93. The conclusion of the results of this service is the results of the pre-test and post-test of the cadres which have experienced a significant increase in cadre knowledge.
Hepatotoxic Test Of Burdock Roots (Arctium Lappa L) On Histopathology Hepar Of Male White Rats (Rattus Norvegicus Wigati, Atika Nur; Faizal, Imam Agus; Puspodewi, Dini
Jurnal Riset Kesehatan Vol 13 No 2 (2024): NOVEMBER 2024
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jrk.v13i2.11903

Abstract

Burdock (Arctium lappa L) is a homologous medical plant that is considered having with many advantages as a traditional medicine. Burdock root contains several substances such as inulin, essential oils, tannins, quercetin,iron, and arctigenin. This study was conducted to determine investigates effect of burdock root extract on the hepar histopathology of male white rats. This study used an experimental method with 20 rats and was divided into 4 groups. The positive control group was given gentamicin induction intramuscularly. The negative control group was given distilled water. The 150 mg/kgBW dose group and the 450 mg/kgBW dose group were given burdock root extract with treatment for 14 days and surgery was performed oin the 15th day to take hepatic organs to make histopathology preparations. The results of the this study were are interpreted by scoring and tabulated, the analysis was is done carried out descriptively with the results, in positive control group found mild damage, the negative group found no damage, in the extract dose group 150mg/kgBW found necrosis, bleeding and vacuolization, and in the extract dose group 450mg/kgBW found degeneration, necrosis, bleeding and vacuolization. The conclusion of this study is the hepatoprotective potential of burdock root extract (Arctium lappa L.) and its related effects on liver tissue in an experimental model. On the other hand, parasitic worms Taenia taeniaeformis were found in the liver which interfered with the interpretation of the results.
Pengaruh Pemberian Ekstrak Buah Pala terhadap Kadar Eritrosit (RBC) dan Granulosit pada Tikus Putih (Rattus norvegicus) dengan Anemia Hasanah, Uswatun; Pangesti, Ira; Puspodewi, Dini
Jurnal Laboratorium Khatulistiwa Vol 9, No 1 (2025): November 2025
Publisher : poltekkes kemenkes pontianak

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30602/jlk.v9i1.2106

Abstract

Anemia is a condition characterized by a decreased number of erythrocytes and an increased number of leukocytes. According to the 2023 Indonesian Health Survey, the prevalence of anemia across all age groups is 16.2%, with a higher rate in women (18%) compared to men (14.4%). Nutmeg (Myristica fragrans Houtt) contains bioactive compounds such as saponins, flavonoids, alkaloids, and essential fatty acids that may contribute to increasing red blood cell counts and modulating leukocyte levels. This study aimed to determine the effect of nutmeg fruit extract on increasing RBC and reducing granulocyte levels in anemic white rats. A total of 25 male rats (200–350 g) were divided into five treatment groups. Anemia was induced using NaNO₂ at a dose of 1.5 mg/kg BW orally. Nutmeg extract was administered at doses of 200 mg/kg BW, 300 mg/kg BW, and 400 mg/kg BW. There were no significant differences (p > 0.05) between the positive control and treatment groups, nor between pre- and post-extract administration. At doses of 200 and 300 mg/kg BW, RBC percentage reached 20.7%. For granulocytes, the 300 mg/kg BW dose produced a higher percentage (27.6%) compared to the 200 and 400 mg/kg BW doses. These findings suggest that nutmeg fruit extract has the potential to support erythrocyte balance in anemia conditions, although further research with larger samples and controlled dosing is needed.%.
Co-Authors Ajeng Puspo Aji Endang Triwahyuni Maharani Frisca Dewi Yunadi Ira Pangesti Kusumawati, Dhiah Dwi Meka Faizal Farabi Mika Tri Kumala Swandari Mubarok, Akhmad Nugraheni, Fajarita Eky Nugroho, Yusuf Eko Pangesti, Ira Retno Retno Saputri, Ratna Dwi Sri Darmawati Uswatun Hasanah Wigati, Atika Nur Yasinta Aritonang