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All Journal Althea Medical Journal Majalah Kulit, Karet, dan Plastik Global Medical and Health Communication Universa Medicina Jurnal Biomedika dan Kesehatan Jurnal ABDINUS : Jurnal Pengabdian Nusantara JK Unila (Jurnal Kedokteran Universitas Lampung) Jurnal Dharma Bhakti Ekuitas Bioscientist : Jurnal Ilmiah Biologi Narra J Jurnal Abdi Masyarakat Indonesia

Meiyanti Meiyanti, Meiyanti

Unknown Affiliation

Author-ID : 515079

Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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Alkaline peptone water plus 0.5% agar suitable for transport of Vibrio cholerae Meiyanti, Meiyanti; Salim, Oktavianus Ch.; Surjawidjaja, Julius E.; Lesmana, Murad
Universa Medicina Vol 30, No 2 (2011)
Publisher : Faculty of Medicine, Trisakti University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2011.v30.95-101

Microbiological procedures for V. cholerae isolation from clinical specimens are important factors in clinical and epidemiological management of cholera. The standard preservation medium for enteric pathogenic bacteria, including V. cholerae, is Cary-Blair medium (CB), a semisolid medium for preservation and transport of specimens containing intestinal bacteria. A special medium for Vibrio organisms is alkaline peptone water (APW), which is both a transport and an enrichment medium. The purpose of this study was to ascertain the suitability of APW supplemented with 0.5% agar (APW-0.5) as a sensititive preservation-transport medium for rectal swab specimens for isolation of V. cholerae. A total of 144 paired rectal swab specimens were collected from children and adults with acute diarrhea. Of each specimen pair, one was placed in CB and the other in APW-0.5, from which they were plated out to thiosulfate citrate bile sucrose (TCBS) agar. Altogether, from both CB and APW-0.5 transported specimens, V. cholerae non-O1 was present in 29 (20.1%) specimens, while only 2 (1.4%) specimens were positive in CB and 9 (6.3%) positive in APW-0.5 transported specimens. The number of V. cholerae non-O1 isolates from APW-0.5 transported specimens was significantly higher (p=0.000) as compared to that from Cary-Blair transported specimens. It may be concluded that for isolation of V. cholerae, specimen transport in APW-0.5 medium was more effective than transport in Cary-Blair medium.

The role of triptans in the management of migraine Meiyanti, Meiyanti
Universa Medicina Vol 28, No 1 (2009)
Publisher : Faculty of Medicine, Trisakti University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2009.v28.49-58

Migraine is one of the most prevalent disorders seen in clinical practice today and also a major cause of disability in the workplace. The prevalence of migraine is highest during the years of peak productivity, ie, between the ages of 25 and 55 years. The triptans are a group of selective 5-hydroxtriptamine (HT)1 serotonin receptor agonists that activate the 5-HT1B/1D receptor and possibly also the 5-HT1A dan 5-HT1F receptors. To date 7 subclasses of serotonin receptors have been identified, namely subclasses 5-HT1 to 5-HT7. Triptan causes cranial vasoconstriction, inhibits peripheral trigeminal activity and the trigeminal afferents. With its triple action, triptans can control acute attacks of migraine. Triptan is contraindicated in patients with previous ischemic or coronary artery disease, cerebral or peripheral vascular disease and other cardiovascular disorders. Triptans should be given immediately after an acute attack of migraine. The triptans are useful in the management of an acute migraine, but are not indicated for preventive therapy of migraine. Several new advances in migraine management have been made in regard to the recognition of the disease, the pathogenesis of migraine, and the phenomenon of central sensitization. More treatment options become available to patients and prescribers, the impact of such therapy on worker productivity will become more important in determining the value of such interventions.

Penatalaksanaan tuberkulosis pada kehamilan Meiyanti, Meiyanti
Universa Medicina Vol 26, No 3 (2007)
Publisher : Faculty of Medicine, Trisakti University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2007.v26.143-151

Tuberkulosis masih menjadi masalah kesehatan di dunia demikian juga tuberkulosis pada kehamilan. Insidens tuberkulosis pada kehamilan makin meningkat. Tuberkulosis pada kehamilan mempunyai gejala klinis yang serupa dengan tuberkulosis pada wanita tidak hamil. Diagnosis mungkin ditegakkan terlambat karena gejala awal yang tidak khas. Tuberkulosis tidak mempengaruhi kehamilan dan kehamilan tidak mempengaruhi manifestasi klinis dan progesivitas penyakit bila diterapi dengan regimen kemoterapi yang tepat dan adekuat. Pemberian regimen yang tepat dan adekuat ini akan memperbaiki kualitas hidup ibu, mengurangi efek samping obat-obat tuberkulosis terhadap janin dan mencegah infeksi yang terjadi pada bayi yang baru lahir. Obat anti tuberkulosis yang diberikan dibagi dalam 2 golongan yaitu obat lini pertama dan lini kedua. Obat lini pertama, kecuali Streptomisin dapat digunakan pada tuberkulosis pada kehamilan. Penggunaan streptomisin dan obat lini kedua (kanamisin, etionamid, kapreomisin) sebaiknya dihindari pada wanita hamil karena efek samping yang akan terjadi pada janin, kecuali dalam keadaan resistensi beberapa obat.

Isolation and antibiotic sensitivity of Aeromonas from children with diarrhea Meiyanti, Meiyanti; Salim, Oktavianus Ch.; Surjawidjaja, Julius E.; Lesmana, Murad
Universa Medicina Vol 29, No 1 (2010)
Publisher : Faculty of Medicine, Trisakti University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2010.v29.14-20

Aeromonas species are gram-negative, motile, facultative anaerobic, rod shaped, oxidase positive bacteria of the recently assigned family Aeromonadaceae. The significance of Aeromonas species as causative agent of human diarrhoea has recently been established. The aim of the present study was to investigate the distribution, and antibiotic sensitivity of Aeromonas in nonhospitalized children with diarrhea.One hundred and seventeen rectal swabs from children with diarhhea were cultured for isolation of Aeromonas organisms as the etiological agents. In addition to Aeromonas, other enteric pathogens were also isolated. Overall, the isolates of enteric pathogens amounted to 36.8%, consisting of Salmonella, Shigella, Aeromonas, and Vibrio. Aeromonas was only found in 5.1% of cultures, with a ratio of A. caviae and A. hydrophila of 2:1, while Salmonella made up the majority of causative organisms with an isolation frequency of 18.8%, followed by Shigella with 11.1%. In this study no isolates of Vibrio cholerae O1 were found as etiological agents of diarrhea; however, V. cholerae non-O1 and V. parahaemolyticus were found in small numbers (<1%). All isolates of Aeromonas were resistant to ampicillin and tetracycline, but sensitive to ciprofloxacin and ceftriaxone, as were the other enteric pathogens. Although the frequency of isolation of these enteric pathogens was higher than for Vibrio spp., their role in infective diarrhea was less clearcut in comparison with Salmonella and Shigella.

Anemia decreases quality of life of the elderly in Jakarta Meiyanti, Meiyanti; Kalumpiu, Joice Viladelvia; Mulia, Julius I
Universa Medicina Vol 28, No 3 (2009)
Publisher : Faculty of Medicine, Trisakti University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2009.v28.152-160

Anemia is a very common disorder both in clinical practice and in the community. The recent rise in the population of the elderly has become the focus of attention in developing countries, because of the increasing longevity of the elderly, whilst the prevalence of anemia increases with age. The objective of this study was to determine the prevalence of anemia and its association with the quality of life in the elderly. A cross-sectional study was conducted from April to June 2008, located in the Mampang Prapatan district, South Jakarta. A total of 298 elderly persons participated in this study, comprising 109 (36.6%) males and 189 (63.4%) females. Anemia was measured by the parameters of hemoglobin and quality of life was assessed by the WHOQOL-BREF instrument, a short version of the WHOQOL-100 instrument. The results of the study showed the prevalence of anemia to be 26.2%, with a higher prevalence rate in females compared with males. The quality of life in the physical, psychological, social and environmental domains differed significantly with decreasing hemoglobin levels, whereas the physical and mental quality of life declined significantly with age. Anemia is thus indicative of a reduction in the quality of life of the elderly.

Epidemiology of osteoporosis in postmenopausal women aged 47 to 60 years Meiyanti, Meiyanti
Universa Medicina Vol 29, No 3 (2010)
Publisher : Faculty of Medicine, Trisakti University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2010.v29.169-176

Osteoporosis is a disorder having the characteristic features of low bone mass and structural degeneration. There are several factors affecting the prevalence of osteoporosis in postmenopausal women, such as age, age at menarche, duration of menopause, dietary or nutritional intakes, life style and level formal education. In connection with the increasing global prevalence of osteoporotic fractures, the purpose of the present study was to determine the prevalence and the influencing factors of osteoporosis in postmenopausal women. A cross-sectional study, involving 203 postmenopausal women aged 47-60 years, was conducted in 4 villages of Mampang Prapatan subdistrict, from February to April 2010. Bone mineral density (BMD) of lumbar spine 1-4, femoral neck, and left radius was measured by dual-energy X-ray absorptiometry (Lunar DPX Bravo Nomusa densitometer, GE Medical Systems) at Budi Jaya Hospital, Jakarta. The T-score threshold, defined as Â£ -2.5 was used to identify subjects with osteoporosis The results of the study showed that the highest prevalence of osteopenia of 45.8% was found in the femoral neck, while the highest prevalence of osteoporosis of 30% was found in the distal radius. Age, duration of menopause, and number of pregnancies yielded a significant correlation with BMD of the lumbar vertebrae and the distal radius. Body mass index (BMI) was also significantly correlated with BMD of lumbar vertebrae, femoral neck and distal radius. Effective strategies for the prevention and management of osteopenia and osteoporosis are needed.

Decreased adiponectin level in adults with central obesity and low 25-hydroxy vitamin D level Pusparini, Pusparini; Merijanti, Lie Tanu; Lesmana, Alvina; Meiyanti, Meiyanti
Universa Medicina Vol 36, No 3 (2017)
Publisher : Faculty of Medicine, Trisakti University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2017.v36.205-213

Background Vitamin D insufficiency is associated with obesity and central obesity, which is in turn associated with the accumulation of visceral fat. Visceral fat secretes adiponectin which has a role in the pathogenesis of the metabolic syndrome, diabetes mellitus and cerebrovascular disease. The aim of this study was to determine the relationship between serum 25-hydroxy vitamin D [25(OH)D] level and adiponectin level in adults with central obesity. Methods This study was a cross sectional study with 80 subjects with central obesity and 80 healthy subjects as controls. The age of the subjects ranged from 55 to 65 years. The data collection included anthropometry and blood biochemistry (lipid profile, fasting blood glucose, 25(OH)D, and adiponectin). The data were analyzed using independent t test with p <0.05.Results Mean waist circumference and 25(OH)D level in the central obesity group were 94.9 Â± 7.8 cm and 14.3 Â± 6.6 ng/mL, respectively, and in the control group 72.4 Â± 5.0 cm and 19.2 Â± 8.6 ng/mL respectively. There were significant differences in adiponectin level between the central obesity group and the control group at the 25(OH)D level of <20 ng/mL (p=0.001), but no significant differences between the two groups at the 25(OH)D level of Â³20 ng/mL (p=0.538).Conclusion The central obesity subgroup with 25(OH)D level of <20 ng/mL have lower adiponectin levels compared with the control group. This study demonstrates the role of adiponectin as a link between insulin resistance and vitamin D status in adults.

Hypoglycemic effect of Phaleria macrocarpa (Scheff.) Boerl dry extract in healthy adults Meiyanti, Meiyanti; Margo, Eveline; Pusparini, Pusparini; Merijanti, Lie Tanu; Lesmana, Alvina
Universa Medicina Vol 37, No 3 (2018)
Publisher : Faculty of Medicine, Trisakti University

BackgroundThe prevalence of diabetes in Indonesia continues to increase and causes many complications. Fruits of Phaleria macrocarpa (Scheff.) Boerl. (PM) are used in the traditional health system of the Indonesians, as effective remedy in the management of diabetes mellitus. The aim of this study was to evaluate the effect and magnitude of doses of PM dry fruit extract (PME) on blood glucose levels in healthy adults.MethodsThis research was of pre-posttest design involving 30 healthy volunteer subjects aged 20-55 years receiving glucose loads. At pre-test the subjects were given orally 75 g glucose, and at post-test they were given PME at doses of 125 mg and 250 mg. Data collection included anthropometric examination and blood glucose level. The area under the curve (AUC) of blood glucose levels was measured at 0, 15, 30, 60, 120 and 180 minutes. Data analysis was performed using paired t-test with p <0.05.ResultsThe percentage of reduction in AUC between pre- and post-test after administration of PME 125 mg was 12.1% and significant (p=0.000). But the percentage of reduction in AUC between pre- and post-test after administration of PME 250 mg was 4.07% and not significant (p=0.06). The reduction in AUC between post-test PME 125 mg vs PME 250 mg showed significant results (p=0.011).Conclusion This study demonstrated that a dose of 125 mg Phaleria macrocarpa (Scheff.) Boerl. dry extract has a hypoglycemic effect in healthy adults, and may therefore be suitable for use as traditional anti-diabetic drug.

Heavy mental workload increase poor sleep quality in informal garment workers Merijanti, Lie T; Pusparini, Pusparini; Meiyanti, Meiyanti; Alvina, Alvina; Sudharma, Novia I; Tjahjadi, Muljadi
Universa Medicina Vol 38, No 3 (2019)
Publisher : Faculty of Medicine, Trisakti University

Background Sleep is needed by the human body so that the performance of body remains optimal when the body is awake, especially during work. Informal workers often work without clear regulations, with inadequate equipment and poor work environment, and pay little attention to occupational health and safety factors. The existence of large work demands with unclear work system arrangements will certainly result in a mental workload in these workers. The objective of this study was to determine the relationship between mental workload and sleep patterns of workers in the informal garment sector. MethodsA cross-sectional study involving 225 informal garment workers was conducted between December 2018 and May 2019. Data collection included respondentsâ€™ demographics, job characteristics, measurement of mental burden and disturbances in sleep patterns. The sleep pattern used the PSQI (Pittsburgh Sleep Quality Index) instrument and the mental burden used the Rating Scale Mental Effort (RSME). A multiple linear regression analysis was used to analyze the data. ResultsThe mean sleep quality was 5.40 Â± 2.54. Multiple linear regression test found that mental workload correlated significantly with sleep quality of workers (Î²=0.016, p=0.012).ConclusionThis study demonstrated that heavy mental workload decreases the quality of sleep in informal garment workers. A good work system management is required so that workers are assigned that portion of the task that is commensurate with their capacity.

Glycated albumin is a better indicator for glucose levels than glycated hemoglobin in patients with diabetes mellitus on insulin therapy Lesmana, Alvina; Pusparini, Pusparini; Meiyanti, Meiyanti; Merijanti, Lie T
Universa Medicina Vol 39, No 1 (2020)
Publisher : Faculty of Medicine, Trisakti University

BackgroundDiabetes mellitus (DM) is a metabolic disease with a large incidence in the world and constitutes a global health problem. By 2030 it is estimated that there will be around 439 million people suffering from DM. Diabetes mellitus is a metabolic disease caused by a lack or absence of the hormone insulin. In type 2 DM pharmacotherapy can be given one of which is insulin. To monitor therapy, random blood glucose, glycated hemoglobin (HbA1c) and glycated albumin (GA) levels can be examined. The objective of this study was to determine the relationship of glycated albumin and glycated hemoglobin (HbA1c) with random blood glucose in insulin-treated diabetics.MethodsA cross-sectional study was conducted involving 92 type 2 diabetic patients treated with insulin. The study used a questionnaire and blood samples. We measured the GA , HbA1C and random blood glucose levels. A multiple linear regression was used to analyze the data. ResultsMean HbA1c was 9.21 Â± 2.15%, mean glycated albumin was 24.4 Â± 8.65%, and mean blood glucose was 229.47 Â± 98.7 mg/dL. Multiple linear regression tests showed that HbA1c (B= 5,544; Ã¢=0.121; p=0.420) and GA (B=5.899; Ã¢=0.517; p=0.001) was signigicantly corelated with random blood gucose, respectively, indicating that glycated albumin is significantly related to and has the greatest influence on glucose level.ConclusionGlycated albumin is correlated with and has greater influence on glucose level than does HbA1c. Glycated albumin could be a better marker for glycemic control than glycated hemoglobin in diabetic patients treated with insulin.

Co-Authors Adang Bachtiar Alfiyyah, Arifah Alvina Alvina Alvina Lesmana, Alvina Anastasya, Karina Shasri Dian Isti Angraini Eddy Purnomo Erlani Kartadinata, Erlani Ernawaty, Tutik Esti Rahayu Eveline Margo, Eveline Faradilla, Meutia Atika Hairunisa, Nany Hasan Basalamah, Hasan Isahak, Marzuki bin Joice Viladelvia Kalumpiu, Joice Viladelvia Julius E. Surjawidjaja, Julius E. Julius I Mulia, Julius I Kartadinata, Noviani Kurniasari Kurniasari Kurniasari Kurniasari Kusuma, Muhammad Cariefzi Zahdffa Lie T Merijanti, Lie T Lie Tanu Merijanti, Lie Tanu Machrumnizar, Machrumnizar Mochtar Lutfie, Mochtar Monica Dwi Hartanti, Monica Dwi Muchtar Lutfie, Muchtar Murad Lesmana Novia I. Sudharma, Novia I. Nur Endah, Nur Oktavianus Ch. Salim, Oktavianus Ch. Pusparini Pusparini Reni Zuraida Ridwan, Alvin Muhamad Rina K. Kusumaratna, Rina K. Sugeng Supriadi, Sugeng Titik Purwati Widowati, Titik Purwati Tjahjadi, Muljadi Triasti Khusfiani Widari Widari, Widari Yana, Risda Yohana Yohana Yohana Yunianto, Andi Eka

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