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All Journal VALENSI Indonesian Journal of Pharmaceutical Science and Technology Jurnal Kimia Riset Chimica et Natura Acta Jurnal Pengabdian Pada Masyarakat Indonesian Journal of Chemistry Jurnal Kreativitas PKM JURNAL FARMASI GALENIKA Pharmacoscript Indonesia Natural Research Pharmaceutical Journal (INRPJ) Science Midwifery Medical Sains : Jurnal Ilmiah Kefarmasian Jurnal Pengabdian Pada Masyarakat Jurnal Farmasi Indonesia Edukasi Masyarakat Sehat Sejahtera (EMaSS) Karya Kesehatan Siwalima Medical Sains : Jurnal Ilmiah Kefarmasian Jurnal Farmasi Galenika Jurnal Pengabdian kepada Masyarakat (PEMAS)

Deden Indra Dinata, Deden Indra

Fakultas Farmasi, Universitas Bhakti Kencana

Author-ID : 526058

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Bersinergi Meningkatkan Pemahaman Nutrisi Melalui Pilar SDGS “Tanpa Kelaparan” Di Desa Rancaekek Kulon Deden Indra Dinata; Meti Sulastri; Fikri Mourly Wahyudi; R. Nety Rustikayanti; Widhya Aligita
Jurnal Kreativitas Pengabdian Kepada Masyarakat (PKM) Vol 5, No 12 (2022): Volume 5 No 12 Desember 2022
Publisher : Universitas Malahayati Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jkpm.v5i12.7613

ABSTRAK Global Hunger Index menunjukkan tingkat kelaparan dan kekurangan gizi di dunia terus mengalami penurunan sejak tahun 2000. Penurunan ini lebih jauh terus diupayakan melalui SDGs, yaitu pilar kedua: mengakhiri kelaparan, mencapai ketahanan pangan, memperbaiki nutrisi dan mempromosikan pertanian yang berkelanjutan. Salah satu indikator dari kondisi kekurangan gizi dapat terlihat dari insidensi kejadian stunting yang muncul sebagai akibat dari keadaan yang berlangsung lama seperti kemiskinan, perilaku pola asuh yang tidak tepat, dan sering menderita penyakit secara berulang akibat kebersihan serta sanitasi yang kurang baik. Metode yang digunakan untuk menyelesaikan masalah tersebut adalah dengan melakukan penyuluhan kepada masyarakat Desa Rancaekek Kulon tentang stunting, dengan tujuan meningkatkan derajat kesehatan masyarakat, meningkatkan pengetahuan, kesadaran dan kepedulian masyarakat mengenai stunting. Target sasaran untuk kegiatan penyuluhan ini yaitu ibu-ibu desa yang memiliki anak balita sehingga dapat lebih paham tentang bagaimana cara mencegah dan menghadapi stunting bila terjadi pada balitanya. Kata Kunci: Tanpa Kelaparan, Stunting, Penyuluhan ABSTRACT The Global Hunger Index shows that the level of hunger and malnutrition in the world has continued to decline since 2000. This reduction is further pursued through the second pillar of SDGs: ending hunger, achieving food security, improving nutrition, and promoting sustainable agriculture. One indicator of the condition of malnutrition can be seen from the incidence of stunting that appears as a result of long-standing conditions such as poverty, inappropriate parenting behavior, and often suffering from repeated diseases due to poor hygiene and sanitation. The method used to solve this problem is by providing counseling to the people of Rancaekek Kulon Village about stunting, with the aim of rising public health, increasing public knowledge,awareness, and concern for for stunting. The targets for this counseling are mothers who have children under five and need education about stunting to understand how to prevent and deal with stunting when it occurs in their toddlers. Keywords: Without Hunger, Stunting, Counseling

Penerapan PHBS Dan Protokol Kesehatan Dalam Waspada Menghadapi Gelombang Ketiga Covid-19 Di Fasilitas Olahraga Kota Bandung Deden Indra Dinata; Santi Rinjani; Meda Yuliani; Rahmat Santoso; Hani Oktafiani
Jurnal Pengabdian Pada Masyarakat Vol 7 No 3 (2022): Jurnal Pengabdian Pada Masyarakat
Publisher : Universitas Mathla'ul Anwar Banten

IMPLEMENTATION OF HEALTHY LIFESTYLE AND HEALTH PROTOCOL IN AWARENESS OF THE THIRD WAVE OF COVID-19 IN BANDUNG CITY SPORTS FACILITIES. Various limitations and lack of understanding in implementing PHBS and strict procedures have become problems in the community. For example, the provision of masks for orphanages that are only waiting for donations from donors, the neglect of health procedures and the lack of public concern for the implementation of PHBS in community sports facilities, cause the need for motivation to be creative and productive while still paying attention and implementing health care programs. The purpose of these efforts is to increase knowledge about health so that later they can carry out health procedures correctly and also increase good and correct PHBS behavior. The method used is educating the application of a clean and healthy lifestyle (PHBS) and health protokols through counseling, making YouTube videos that are registered as intellectual property, providing supporting facilities and information and education communication in collaboration with health promotion officers of UPT Puskesmas Cipadung. The results showed that this activity was frequently needed by partners and really useful, seen from the increase in participants' understanding of the material presented and the implementation of health protokols in the sports facility environment.

REVIEW ARTIKEL: ANALISIS MOLECULAR DOCKING SENYAWA GOLONGAN FLAVONOID SEBAGAI ANTIBAKTERI TERHADAP RESEPTOR PBP 2A BAKTERI MRSA: ARTICLE REVIEW: MOLECULAR DOCKING ANALYSIS OF FLAVONOID COMPOUNDS AS ANTIBACTERIALS AGAINST PBP 2A RECEPTORS OF MRSA BACTERIA Jajang Japar Sodik; Deden Indra Dinata
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 8 No 2 (2023)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v8i2.736

Methicillin-resistant Staphylococcus aureus (MRSA), bakteri yang resisten terhadap antibiotik b-laktam seperti methicillin, merupakan masalah klinis yang terus-menerus mempengaruhi seluruh dunia. Resistensi terjadi akibat adanya modifikasi struktural protein pengikat penisilin (PBP)2a bakteri MRSA. Flavonoid adalah salah satu senyawa aktif terpenting yang secara alami terdapat pada tanaman. Beberapa flavonoid telah terbukti memiliki sifat antibakteri pada penelitian sebelumnya. Penambatan molekul (Molecular Docking) merupakan salah satu metode in silico (virtual) berbasis struktur yang paling sering digunakan dan paling sederhana. Tujuan dari review jurnal untuk mengetahui senyawa turunan flavonoid pada tanaman obat yang berpotensi untuk dikembangkan sebagai pengobatan antibakteri terhadap bakteri MRSA berdasarkan dari beberapa studi secara in-silico. Metode pencarian jurnal dilakukan melalui website https://scholar.google.co.id/ dan Pubmed dengan menggunakan kata kunci Molecular Docking Flavonoid Methicillin Resistant Staphylococcus aureus. Hasil yang didapat adalah dari 31 senyawa aktif turunan flavonoid yang berpotensi menghambat reseptor PBP2a bakteri MRSA. Pada PDB ID IMWT didapatkan senyawa terbaik Diferulic acid memiliki nilai binding affinity sebesar -102.4, pada PDB ID 1VQQ didapatkan senyawa terbaik Hesperidin memiliki nilai binding affinity sebesar -9.2 dan pada PDB ID 4DKI didapatkan senyawa terbaik Quercetin 3-O-rutinoside memiliki nilai binding affinity sebesar -91.56. Kata kunci : Molecular Docking , Methicillin-resistant Staphylococcus aureus (MRSA), Flavonoid.

The Edukasi Pendampingan Pola Asuh Keluarga Dalam Upaya Pencegahan Stunting Pada Balita Sri Lestari Kartikawati; Deden Indra Dinata; Heni Nurakilah; Fenti Fatmawati; Suherdin Suherdin; Baharudin Lutfi
Jurnal Pengabdian Pada Masyarakat Vol 8 No 2 (2023): Jurnal Pengabdian Pada Masyarakat
Publisher : Universitas Mathla'ul Anwar Banten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30653/jppm.v8i2.349

Stunting pada balita berdampak besar pada kesehatan anak saat ini dan di masa mendatang. Faktor penyebab stunting antara lain pekerjaan ibu, tinggi badan ayah dan ibu, pendapatan keluarga, jumlah anggota keluarga, pola asuh, dan pemberian ASI eksklusif. Posyandu di RT 01 RW 12 di Desa Cinunuk memiliki kejadian stunting yang lebih tinggi dibandingkan dengan RW lain di Desa Cinunuk. Permasalahan stunting yang dihadapi oleh mitra meliputi beberapa faktor penyebab, seperti latar belakang pendidikan mayoritas lulusan SMA dengan tingkat pengetahuan tentang gizi yang masih rendah, pekerjaan penduduk mayoritas mengurus rumah tangga dan buruh harian lepas. Program pengabdian kepada masyarakat ini dilakukan untuk menjawab permasalahan mitra melalui penyuluhan terkait pencegahan stunting pada balita, dengan tujuan agar masyarakat khususnya ibu yang memiliki balita memahami pentingnya pencegahan stunting dengan pemantauan tumbuh kembang yang dilakukan setiap bulan di Posyandu. Metpde yang dilakukan adalah dengan penyuluhan langsung pola asuh keluarga, memberdayakan kader PKK Desa dan RW, demonstrasi pemberian nutrisi serta monitoring dan evaluasi. Pengabdian masyarakat yang telah dilaksanakan di RW 12 Kelurahan Cinunuk Kecamatan Cileunyi Kabupaten Bandung dengan tema Pendidikan Pendampingan Keluarga Dalam Upaya Mencegah Stunting pada Balita, dapat memberikan pemahaman tentang pentingnya pola asuh yang diberikan untuk memantau pertumbuhan dan perkembangan balita. pembangunan dalam upaya pencegahan stunting. . Stunting in toddlers has a major impact on children's health now and in the future. Factors causing stunting include mother's occupation, father's and mother's height, family income, number of family members, parenting style, and exclusive breastfeeding. One Posyandu in RT 01 RW 12 in Cinunuk village has a higher incidence of stunting compared to other RWs in Cinunuk village. The problems related to stunting faced by partners include several causal factors, such as the majority of education backgrounds were high school graduates, the majority of the population's work was taking care of the household and casual daily labourers. The program was carried out to answer partners' problems through counseling related to stunting prevention in toddlers, with the aim of the community, especially mothers with toddlers, to understand the importance of preventing stunting by monitoring growth and development which is carried out every month at the Posyandu. Community service that has been carried out in RW 12 Cinunuk Village, Cileunyi District, Bandung Regency, with the theme of Family Parenting Assistance Education in Efforts to Prevent Stunting in Toddlers, can provide an understanding of the importance of parenting given to monitoring toddler growth and development in an effort to prevent stunting.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v8i2.736

COMPARISON OF ANALYSIS METHODS FOR CURCUMIN DETERMINATION: A LITERATURE REVIEW Jajang Japar Sodik; Deden Indra Dinata; R. Herni Kusriani; Garnadi Jafar
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 8 No 4 (2023)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v8i4.850

Curcuminoids such as curcumin, demethoxycurcumin (DMC), and bisdemethoxycurcumin (BDMC) are the major bioactive components found in Curcuma species, including turmeric (Curcuma longa L.). Curcumin is a polyphenol that is used as an antioxidant. Various analytical methods have been developed for the detection of curcumin, each with its advantages and limitations. Selection of an appropriate analytical method is crucial for obtaining accurate results. Although critical reviews on the chemical, biological, and pharmacological properties of curcumin are widely available, reviews specifically focusing on the different analytical methods for curcumin are limited. This review article aims to provide an overview of several analytical methods for the determination of curcumin. This is expected to encourage readers to choose a suitable analytical method for their specific needs. The articles used in this review were sourced from international English-language publications obtained from Science Direct, PubMed, and Google Scholar. The search was performed using keywords such as "Instrumental analysis of curcumin" and "Analytical techniques for curcumin analysis." The results reveal that spectrophotometric methods are simple techniques used to estimate curcumin content; however, their utility is limited to cases where the concentration of each curcuminoid is not a critical quality parameter. Accurate quantification and detection of trace amounts of curcuminoids and metabolites require the use of chromatographic separation methods combined with mass spectrometry detection (LC-MS/MS) because of their high accuracy, reproducibility, and sensitivity with low limits of detection (LOD) and lower limits of quantification (LLOQ). Keywords: Analytical methods, Curcumin, Determination

ARTICLE REVIEW: UTILIZATION OF CURCUMIN AS AN ANTI-CANCER AGENT Abdul Mulki Irpani; Deden Indra Dinata; Garnadi Jafar
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 9 No 1 (2024)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v9i1.1062

The uncontrolled growth of abnormal cells in one area of the body can spread to other tissues and create more cancer cells, a disease known as cancer. Malignant cancer cells have the potential to become fatal. After cardiovascular disease, cancer is the second most common cause of mortality. Numerous cancer types exist, including stomach, liver, colorectal, lung, breast, and cervical cancers. More than 70% of cancer-related deaths occur in low- and middle-income nations, and the number of cancer-related deaths is predicted to rise steadily, hitting 11.5 million by 2030. Some of the resources utilized to look up information on curcumin's application as an anticancer agent are PubMed, Science Direct, and Google Scholar. Most of the articles that were used were published between 2013 and 2023, or within the last ten years. These journals were found using the following keywords: "Curcumin," "Cancer," "Curcumin as an Anticancer," and "Utilization of Curcumin as an Anticancer Agent." Scholars from many nations have conducted comparable investigations on the application of curcumin as an anticancer agent. Furthermore, it has been established that curcumin directly inhibits cancer cells when used as an anticancer drug. This suggests that curcumin does have anticancer properties. Keywords: Curcumin, Cancer, Curcumin as an Anticancer agent

REVIEW: THE POTENTIAL OF HERBAL PLANTS AS ANTI-ALOPECIA MEDICINES Arif Rubianto; Garnadi Jafar; Deden Indra Dinata; Jajang Japar Sodik
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 9 No 2 (2024)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v9i2.1204

Hair loss, or alopecia, is a common dermatological condition that affects up to 2% of the world's population. It is often caused by genetic factors, such as male or female pattern baldness, but can also be attributed to various environmental factors, an imbalanced diet, or chronic illnesses. While hair loss is not life-threatening, it can lead to significant anxiety, depression, and other psychological issues, ultimately affecting one's quality of life. Various treatments for baldness, including synthetic drugs like minoxidil and finasteride, or herbal remedies, have been approved by the Food and Drug Administration. Although synthetic drugs are effective, they may come with potential side effects. Natural remedies have been proposed as a viable option for treating baldness because many chronic disorders can lead to alopecia. Therefore, this review focuses on identifying efficient alternative treatment agents with limited side effects. Specifically, it considers medicinal plants as potential healing agents for treating baldness. To gather relevant information for this study, several databases were searched, including Scopus, PubMed, and Google Scholar. Comprehensive searches were conducted using various search terms, such as "baldness," "alopecia," "natural remedies for baldness," "herbal treatment for baldness," and others, to extract relevant scientific articles. Many medicinal plants and natural compounds have shown potential for reducing baldness, thanks to their anti-inflammatory and antioxidant properties. According to existing literature, extracts of medicinal plants and formulations derived from plants, such as Eclipta alba (L.) Hassk, Arctium lappa L., Centella asiatica L., Morinda citrifolia, Acorus calamus var. angustatus, Alpinia zerumbet, ...

Identification of Angiotensin Receptor Blocker II Ligands from Gotu Kola (Centella asiatica L.) Extract: an In Silico Study Dinata, Deden Indra
Indonesian Journal of Pharmaceutical Science and Technology Suppl. 5, No. 2 (2023) Special Issue for The 3rd Bandung International Teleconference on Pharmacy (B
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/ijpst.v0i0.50346

Non-communicable diseases, including hypertension, are a significant source of health issues in developed nations[MOU1] . Angiotensin II Receptor Blocker (ARB) is frequently used as the first-line treatment for hypertension. ARB works by inhibiting Angiotensin II which can cause vasoconstriction of entire blood vessels[l2] . This study aimed to find lead compound of 54 compounds obtained from gotu kola (Centella asiatica L.) in order to determine the antihypertensive activity. The target of drug action chosen in this study was the type 1 angiotensin II receptors (AT1). Molecular docking and molecular dynamics simulation were chosen as the methods in this study to predict the interaction and the affinity and stability of the interaction. Based on the results of molecular docking, it was found that the compound of campesterol, centellasaponin B, and corosolic acid gave good affinity to the targets. The test ligand that the Ki and DG values were close to the natural ligand (Olmesartan) campesterol with a value of -10.79 kcal/mol and 12.28 nM. Meanwhile, in the molecular dynamics simulation test, it was found that corosolic acid has good interaction stability with the targets and was constant from the beginning of the simulation to 100 ns, while for MMGBSA centellasaponin B the lowest total energy value was -71.4347 kcal/mol. It was concluded that the gotu kola (Centella asiatica L.), compound corosolic acid, and centellasaponin B had the potential as a lead compound that had affinity and stability for the interaction with the AT1 receptor as antihypertensives.

Mengatasi Darurat Sampah dengan Loseda dan Kolaborasi Pemangku Kepentingan di Kelurahan Cipadung Kulon Bandung Dinata, Deden Indra; Nurdiansyah, Ilyas; Helena, Deni Fransisca; Idar, Idar; Pertiwi, Nisa Indah; Nani, Shinta Ayu; Rokhmah, Siti
Jurnal Pengabdian Pada Masyarakat Vol 9 No 3 (2024): Jurnal Pengabdian Pada Masyarakat
Publisher : Universitas Mathla'ul Anwar Banten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30653/jppm.v9i3.889

Kelurahan Cipadung Kulon kecamatan Panyileukan merupakan salah satu bagian dari wilayah timur kota Bandung dengan luas lahan sebesar 133,34 Ha. Berdasarkan studi pendahuluan, diperoleh gambaran adanya permasalahan mitra yang utama yaitu kedaruratan sampah dan persoalan limbah rumah tangga. Kegiatan pengabdian masyarakat ini bertujuan memberikan solusi dan edukasi dalam mengatasi persoalan mitra untuk mengendalikan dampak dan resiko terhadap kesehatan agar menjadi nilai tambah di masyarakat. Metode pelaksanaan meliputi studi pendahuluan dan survey lokasi, identifikasi masalah mitra, pra-pelaksanaan dengan membangun jejaring mitra dan melibatkan pemangku kepentingan terkait, pelaksanaan edukasi dan pemberdayaan masyarakat dengan melibatkan kader setempat, evaluasi dan pengelolalaan keberlanjutan. Hasil implementasi program menunjukkan adanya implementasi pengendalian darurat sampah antara lain dengan Loseda (Lodong Sesa Dapur) melalui kerjasama dengan Dinas Lingkungan Hidup kota Bandung, adanya jejaring kader setempat berkelanjutan melanjutkan pengelolaan dan pencegahan Bandung Darurat Sampah. Program pengabdian masyarakat ini secara sistematis mampu menjadi alternatif solusi penyelesaian masalah mitra dengan melibatkan pihak berkepentingan secara berkelanjutan. Cipadung Kulon Village, Panyileukan District is one part of the eastern region of Bandung City with a land area of 133.34 Ha. Based on the preliminary study, was obtained of the main partner problems, including waste emergencies and household waste problems. This community service activity aims to provide solutions and education in overcoming partners problems to control impacts and risks on health to become added value in the community. Implementation methods include preliminary studies and location surveys, identification of partner problems, pre-implementation by building a network of partners and involving relevant stakeholders, implementation of community education and empowerment by involving local cadres, evaluation and sustainability management. The results of the program implementation showed the implementation of emergency waste control, including by Loseda (Lodong Sesa Dapur) through collaboration with the Bandung City Environmental Service, the existence of a sustainable local cadre network to continue the management and prevention of Bandung waste emergency. This community service program was systematically capable of being an alternative solution to solving partner problems by involving interested parties on an ongoing basis.

Co-Authors Abdillah, Lutfi Abdul Mulki Irpani Abdul Mulki Irpani Achmad Fadjar Aiyi Asnawi Aiyi Asnawi Aiyi Asnawi Aiyi Asnawi Andriansyah, Ivan Anggraeni, Vina Juliana Arif Rubianto Baharudin Lutfi Darwati Darwati Darwati Darwati Dewi Kurnia Dewi Kurnia Dinayanti, Westi Nur Ellin Febrina Fadjar, Achmad Farizan Nur Fazrina Fauzan Zein Fauzan Zein Muttaqien Fenti Fatmawati Fikri Mourly Wahyudi Firdaus, Oktri Muhammad Garnadi Jafar, Garnadi Hani Oktafiani Hardhi Suryatno Hardhi Suryatno, Hardhi Helena, Deni Fransisca Heni Nurakilah Ida Musfiroh Ida Musfiroh -, Ida Musfiroh Idar, Idar Ilyas Nur Fatahillah Irfani, Abdul M. Jajang Japar Sodik Kosasih Kosasih KOSASIH KOSASIH, KOSASIH Lilis Silviana Lilis Silviana Lutfi Abdillah Meda Yuliani Meti Sulastri Mohamad Nurul Azmi Muhamad Ilham Bintang Mutmainah, Siti Saidah Muttaqin, Fauzan Z. Muttaqin, Fauzan Zein Nani, Shinta Ayu Nenden Ayu Lisniawati Nurdiansyah, Ilyas Nurul Qomarilla Oktri Muhammad Firdaus Pertiwi, Nisa Indah Qomarilla, Nurul R Nety Rustikayanti Rahmat Santoso Rani Maharani Rani Maharani Rinjani, Santi Roni, Asep Sari Nurmala Septianti, Regina Dwi Shelvy E Suherman Shelvy E Suherman, Shelvy E Silviana, Lilis Siti Rokhmah SITI SAIDAH Siti Saidah Mutmainah Sodik, Jajang J. Soni Muhsinin Sri Lestari Kartikawati Suherdin Tenny Putri Wikayani Tenny Putri Wikayani, Tenny Putri Tri Mayanti Unang Supratman Vina Juliana Anggraeni Widhya Aligita Winasih Rachmawati Yoshihito Shiono Yuliantini, Anne Yusril Panji

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