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All Journal CAKRA KIMIA (Indonesian E-Journal of Applied Chemistry) Jurnal Kimia (Journal of Chemistry) Chimica et Natura Acta Widyadari : Jurnal Pendidikan Jurnal Pengabdian Masyarakat Asia Hydrogen: Jurnal Kependidikan Kimia Widyadari : Jurnal Pendidikan Emasains : Jurnal Edukasi Matematika dan Sains Jurnal Ilmiah Ilmu Terapan Universitas Jambi Jurnal Pengabdian Kepada Masyarakat Widya Mahadi Usadha Obat: Jurnal Riset Ilmu Farmasi dan Kesehatan
Ni Made Sukma Sanjiwani
Universitas Mahasaraswati Denpasar
Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Earth & Planetary Sciences Economics, Econometrics & Finance Education Electrical & Electronics Engineering Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Journal : Usadha

 1 
Pengujian Fitokimia dan Penentuan Kadar Senyawa Saponin Pada Ekstrak Etanol Bunga Telang (Clitoria ternatea L.) Nugraha, Nyoman Dhamapada; Sukma Sanjiwani, Ni Made; Wahyu Udayani , Ni Nyoman
Usadha Vol 3 No 1 (2024): Usadha: Jurnal Integrasi Obat Tradisional
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/usadha.v3i1.7345

Abstract

Butterfly pea flower (Clitoria Ternatea L.) has long been used as a traditional medicine to cure various diseases so that it is used as a family medicinal plant (TOGA). Telang flower (Clitoria Ternatea L.) has properties as an antimicrobial, anthelmintic, or antiparasitic and insecticidal agent, fever medicine and pain reliever, anticancer, antioxidant, lowering blood sugar levels, anti-cholesterol, hypo-allergenic, immunomodulator and can be used in the treatment of wounds and can treat red eyes, tired eyes, skin diseases, and anti-toxins (Purba, 2020). This study aims to determine the presence or absence of saponins in the ethanol extract of butterfly pea and to determine the levels of saponins contained in the ethanol extract of butterfly pea (Clitoria Ternatea L.). A qualitative test was carried out by putting 0.5 gram of butterfly pea flower simplicia powder (Clitoria Ternatea L.) into a test tube, then adding 10 ml of hot water, shaking vigorously for 10 seconds and adding 2N HCl, then a quantitative test was carried out using the gravimetric method. Based on the research results that have been carried out positive butterfly pea flower extract (Clitoria Ternatea L.) contains saponin compounds with a saponin content of 1.54% using the gravimetric method. Keywords: Butterfly Pea Flower (Clitoria Ternatea L.), Saponins, Gravimetric Method.
Uji Aktivitas Antibakteri Ekstrak Etanol Daun Jelatang (Urtica dioica L.) Terhadap Bakteri Staphylococcus aureus Esti Trisna Putri, Ni Komang; Surya Rahadi, I Wayan; Sukma Sanjiwani, Ni Made
Usadha Vol 2 No 3 (2023): Usadha: Jurnal Integrasi Obat Tradisional
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/usadha.v2i3.7416

Abstract

Nettle leaf (Urtica dioica L.) is the most widely known species in the urtica genus and has many benefits for the community, namely for medicine, cosmetics and for consumption. Nettle leaves contain alkaloids, flavonoids, and saponins. These compounds can be known to have antibacterial activity. Staphylococcus aureus bacteria are gram-positive bacteria that can produce a yellow pigment, are facultative aerobes and colonies tend to be shaped like grapes. Naturally Staphylococcus aureus is a normal flora in humans, which is often found on the skin, nose and eyes. This study aims to determine the antibacterial activity of nettle leaf ethanol extract (Urtica dioica L.) against Staphylococcus aureus bacteria . The sample used was nettle leaves (Urtica dioica L.) taken in Buruan Village, Kec. Penebel, Kab. Tabanan. This research was conducted using laboratory experimental methods. The ethanol extract of nettle leaves was prepared by the maceration method using 96% ethanol and the viscous extract was obtained using a rotary evaporator . This study used the disc diffusion method with nutrient agar media. The concentrations of the nettle leaf ethanol extract used were 5%, 10%, and 15%. The antibacterial activity test showed that the ethanol extract of nettle leaves could inhibit the growth of Staphylococcus aureus bacteria at each concentration of nettle leaf extract (Urtica dioica L.) with the following inhibition zone diameters: concentrations of 5% (6.55 mm), 10% (1.06 mm), and 15% (0.48 mm). The nettle leaf ethanol extract had the highest antibacterial activity at a concentration of 5%, namely 6.55 mm, which was included in the medium category. Keywords : nettle leaf (Urtica dioica L.), antibakterial, Staphylococcus aureus.
Pengujian Fitokimia dan Penentuan Kadar Flavonoid Ekstrak Etanol Bunga Telang (Clitoria ternatea L.) Lusi Puspitasari, Ni Wayan; Sukma Sanjiwani, Ni Made; Wahyu Udayani , Ni Nyoman
Usadha Vol 3 No 2 (2024): Usadha: Jurnal Integrasi Obat Tradisional
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/usadha.v3i2.7278

Abstract

  Flavonoids are polyphenolic compounds, so they have the chemical properties of phenolic compounds, which are slightly acidic, soluble in bases, and are polyhydroxy (hydroxy groups) and polar. Flavonoids are found in many plants such as butterfly pea. This study aims to determine the presence or absence of flavonoids in the ethanol extract of butterfly peas and the levels of flavonoids contained in the extract of butterfly peas (Clitoria ternatea L.). This research was conducted by extracting the butterfly pea flower by maceration with ethanol and phytochemical testing of flavonoids. Flavonoid content was determined by the Chang method using UV-visible spectrophotometry. The data obtained were analyzed using Lambert Beer's law. The results of this study indicate that the ethanol extract of butterfly pea flowers positively contains flavonoid compounds which cause a red color after phytochemical testing. Determination of the levels carried out obtained an average level of flavonoids of 0.28107%.
Formulasi Dan Uji Mutu Fisik Sediaan Sabun Padat Dengan Penambahan Ekstrak Etanol Buah Pepaya (Carica papaya L.) Putra, Aditya; Sanjiwani, Ni Made Sukma; Suradnyana, I Gede Made; Dewi Agustini, Ni Putu
Usadha Vol 3 No 3 (2024): Usadha: Jurnal Integrasi Obat Tradisional
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/usadha.v3i3.7296

Abstract

Papaya fruit contains secondary metabolite compounds such as saponins. The secondary metabolites needed in soap production are saponins. The purpose of this study was to determine whether the addition of ethanol extract of papaya fruit (Carica papaya L.) with concentrations of 2.4 and 6% in solid soap preparations can produce good physical quality and to determine the difference between formula 0 (without extract) and formula I, II and III (with extract concentrations of 2, 4 and 6%) in the physical quality obtained. This research is an experimental study, starting with making extracts formulated into solid soap form with variations in extract concentrations of 2.4 and 6%. The soap produced is white in formula 0 and formula I with an aria fragrance aroma. In contrast, formula II is yellow and formula III is orange with the aroma of papaya fruit ethanol extract and in the four formulas obtained a solid preparation. The homogeneity test results on all formulas are homogeneous. The pH test results obtained the lowest pH value in formula II and formula III with a pH value of 9 while the highest pH value was obtained in formula 0 with a pH value of 11. The test results of the height and stability of the foam obtained the highest foam height in formula III (7.43 cm) with foam stability of 66.82% while the lowest foam height was obtained in formula 0 (6.23 cm) with foam stability of 78.59%. The results of the physical quality test show that the soap meets homogeneous criteria, pH ranges from 9-11, has a foam height of 1.3-22 cm and foam stability between 60-90% in accordance with the requirements of SNI No. 3532-2016.
Co-Authors Adelia Vinanda Ketut Aditya Putra, Aditya Agung Ari Chandra Wibawa Agung Ari Chandra Wibawa Ananda gayatri Arandika, I Wayan Wisma Ayu Mirah Mariati Ni Putu Dewa Ayu Ika Pramitha Dewa Ayu Ika Pramitha Dewa Ayu Sri Handani Dewi Agustini, Ni Putu Esti Trisna Putri, Ni Komang Gde Nyoman Astika I Made Dedy Ariawan I Made Dira Swantara I WAYAN SUDIARSA I Wayan Sudiarsa I Wayan Surya Rahadi Ketut Agus Adrianta Luh Nik Pradnya Anggi Lusi Puspitasari, Ni Wayan Megawati, Fitria Mirah Mariyati Ni Putu Ayu Ni Kadek Lidia Ayu Aristina Ni Luh Rustini Ni Made Suaniti Ni Nyoman Wahyu Udayani Ni Putu Ayu Mirah Mariati NI PUTU AYU MIRAH MARIATI Ni Wayan Trisna Dewi Nugraha, Nyoman Dhamapada Nyoman Budiartha Siada P Purwanto Paramitha, Dewa Ayu Ika Puguh Santoso Putu Angga Permana Putra Rahadi, I Wayan Surya Suradnyana, I Gede Made Surya Rahadi, I Wayan Wardana, I Made Wisnu WIWIK SUSANAH RITA