Claim Missing Document
Check
Articles

Found 16 Documents
Search

ISOLASI DAN UJI SITOTOKSIK SENYAWA LIMONEN DARI KULIT BATANG KASTURI (Mangifera casturi) Kholifatu Rosyidah
Bioscientiae Vol 8, No 2 (2011): Bioscientiae Volume 8 No 2
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (316.888 KB) | DOI: 10.20527/b.v8i2.191

Abstract

The air-stem barks of M.casturi were extracted with Methylene Chloride (MTC). The MTC extract’s had treatment with Brine Shrimp Lethality Test (BSLT) than analyzed with probit and resulted LC50= 47,31 ppm. MTC extract’s was fractionated by Vacuum Liquid Chromatography and recrystalization obtained pure compounds. The compounds was analyzed with GC-MS (Gas chromatography-Mass Spectroscopy) and cytotoxic test with cancer cell Leukemia P388. This compound is limonene and have IC50=70 ppm.
Uji Sitotoksik Ekstrak Alkaloid Daun Belimbing Wuluh (Averrhoa bilimbi L.) terhadap Larva Udang (Artemia salina) Mariani Mariani; Kholifatu Rosyidah; Kamilia Mustikasari
Jurnal Natural Scientiae Vol 1, No 1 (2021): November 2021
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jns.v1i1.4421

Abstract

Research on cytotoxic test of alkaloids extract of belimbing wuluh leaves has been conducted. The objective of this research are to determine the yield, toxicity, TLC chromatogram pattern, and compounds in alkaloids extract of belimbing wuluh leaves with GC-MS. Alkaloid extraction process uses acid base method, the phytochemical tests was carried out with reagents Dragendorff, Wagner and Meyer. Toxicity test of alkaloids extract of belimbing wuluh leaves with BSLT method on A. salina larvae to determine LC50 value. Alkaloids extract of belimbing wuluh leaves were analyzed by TLC and GC-MS. The yield of alkaloids extract of belimbing wuluh leaves obtained was 10, 13 %. The results of phytochemical tests were carried out which showed positive containing alkaloids. LC50 value of the alkaloids extract of belimbing wuluh leaves indicated that is very toxic. The LC50value obtained is 9.170 ppm. Analysis using TLC with eluent of n-hexane: ethyl acetate (8:2) showed 5 stains. GC-MS analysis showed are alkaloid compound with an odd molecular weight.
Personal Hygiene Practices To Reduce The Risk Of Soil-Transmitted Helminth Infection In Farmers Rosyidah, Kholifatur; Maulidia, Aulia; Indrasasi, Adzraa Sadira Ranu; Kurniyawan, Enggal Hadi; Afandi, Alfid Tri; Nur, Kholid Rosyidi Muhammad; Kurniawan, Dicky Endrian
International Journal of Midwifery and Health Sciences Vol. 2 No. 2 (2024): IJMHS Vol 2 No 2 (2024)
Publisher : Rajaki of Tulip Medika Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61777/ijmhs.v2i2.75

Abstract

Backgrounds: Soil-transmitted Helminths infections have become a frequent phenomenon among farmers due to their lack of hygiene, making it easy for nematode worms to enter the body. Soil-transmitted helminths can affect nutritional status, resulting in anemia, loss of appetite, and damage to the intestines. To overcome this phenomenon, adequate personal hygiene in farmers is needed. Purpose: The purpose of this study is to analyze how personal hygiene can affect the incidence of Soil-Transmitted Helminths infection. Methods: The method used is a literature review using 10 kinds of literature from 3 sources, namely Google Scholar, PubMed, and Science Direct with a publication range from 2020-2024. Result: The results showed that some articles showed an association between personal hygiene and the incidence of soil-transmitted helminths. Good personal hygiene can prevent the entry of nematode worms into the digestive tract of the body. Besides that, some articles also showed no association between personal hygiene and soil-transmitted helminth infection. Conclusion: Adequate personal hygiene such as always using gloves and complete personal protective equipment while working, always washing hands before eating, and maintaining environmental hygiene is needed by farmers to avoid the incidence of soil-transmitted helminth infection.
Pengaruh Waktu Reaksi Terhadap Viskositas Dan Densitas Tetraetil Ortosilikat Dari Silika Abu Sekam Padi Mujiyanti, Dwi Rasy; Nisa, Hayatun; Rosyidah, Kholifatu; Ariyani, Dahlena; Abdullah, Abdullah
Indonesian Journal of Chemical Research Vol 8 No 1 (2020): Edisi Bulan Mei (Edition for May)
Publisher : Jurusan Kimia, Fakultas Sains dan Teknologi, Universitas Pattimura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30598/ijcr.2020.8-dwi

Abstract

Tetraethyl Ortosylicate (TEOS) is a material is widely used in industrial fields. One source of silica (SiO2) is rice husk ash. In this study was determined the effect of reaction time on viscosity and density in making TEOS from silica rice husk. Silica resulting from the purification of rice husk ash is used in the TEOS manufacturing process by examining the variation of reaction time. One mole of ethanol and 0.25 mole of silica powder were added into 250 ml of round bottom flask followed by the addition of 1 gram of CuO/Al2O3 catalyst then the mixture was refluxed for 30, 35, 40, 45 and 50 hours with sufficient stirring and a temperature of 90 °C. The FTIR characterization results show that there are three main functional groups, namely the -OH, Si-O and C-O groups in the five TEOS synthesis results. Wavenumbers of the –OH functional groups obtained ranged from 3349 cm-1 - 3315 cm-1; Si-O functional groups range from 813 cm-1 - 606 cm-1 and C-O functional groups range from 1105 cm-1 - 1040 cm-1. Reaction time has no significant effect on viscosity. Reaction time has no significant effect on the density and density of the resulting TEOS.
Pembuatan dan Uji Kualitas Sabun Transparan dengan Bahan Aktif Ekstrak Kulit Kayu Bangkal (Nauclea subdita) Khas Kalimantan Selatan Rahmad, Amalia Fateha; Natasya, Sybilla; Al Wiah H.J, Tuty; Aufa, Syinta Febriyanti; Rosyidah, Kholifatu
Jurnal Natural Scientiae Vol 5, No 2 (2025)
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jns.v5i2.17280

Abstract

The use of synthetic soaps containing harmful ingredients has driven consumers toward natural soap alternatives. Transparent soap offers the advantage of producing a softer lather and containing moisturizing agents that help prevent dry skin, making the development of transparent soaps with natural active ingredients essential for maintaining skin health and beauty. This study aimed to develop a transparent soap formulated with bangkal wood bark (Nauclea subdita) extract, a native plant of South Kalimantan rich in secondary metabolites such as alkaloids, flavonoids, polyphenols, and saponins. Previous studies have reported that these compounds possess natural antioxidant and sunscreen properties, as well as anti-inflammatory, antiplasmodial, antipyretic, and antimicrobial potentials. The methodology included reflux extraction using 96% ethanol, soap formulation through saponification, and comprehensive quality evaluation. Tests conducted included measurements of water content, pH, chloride content, ethanol-insoluble matter, free fatty acids/alkali, total fatty matter, unsaponified fat, foam stability, and organoleptic properties. The results showed that the transparent soaps with bangkal wood bark extract met the SNI 3532:2021 standards for water content, pH, ethanol insoluble matter, chloride content, foam stability, and total fatty matter across all extract concentrations. However, soap D (6 grams extract) exceeded the acceptable limit for free fatty acids. Organoleptic evaluation indicated that all formulations were well accepted by the panelists. Therefore, the bangkal wood bark extract demonstrates strong potential as a natural active ingredient for developing transparent soap formulations that meet quality standards.
Uji Antioksidan Senyawa Terpenoid Dari Fraksi M-17 Ekstrak Metilena Klorida Kulit Batang Tumbuhan Kasturi (Mangifera casturi) Budi Prayitno; Kholifatu Rosyidah; Maria Dewi Astuti
Journal of Pharmascience Vol. 3 No. 1 (2016): Jurnal Pharmascience
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v3i1.5832

Abstract

 ABSTRAK  Penelitian tentang isolasi senyawa dari ekstrak metilen klorida telah dilakukan. Hasil analisis diduga senyawa tersebut adalah senyawa (23-E)-27-nor-3β-hidroksisikloart-23-en-25-on. Tujuan dari penelitian ini adalah untuk mengetahui aktivitas antioksidan terhadap radikal DPPH. Uji aktivitas antioksidan dilakukan dengan metode DPPH (1,1-difenil-2-pikril hidrazil). Vitamin C digunakan sebagai kontrol positif. Senyawa 1 memiliki nilai IC50 sebesar 6.751 ppm dan IC50 vitamin C sebesar 2,98 ppm, sehingga senyawa ini tidak aktif antioksidan.  Kata kunci: Mangifera  casturi., antioksidan, triterpenoid  ABSTRACT Research on the isolation of compounds from the fraction of M 17 of methylene chloride extract has been done. The suspected compound is (23-E)-27-nor-3β-hydroxycycloart-23-ene-25-one. The aims of this study were to determine the antioxidant activity against DPPH radical fraction isolates extracts of plants kasturi to DPPH. The antioxidant activity assay was conducted by DPPH (1,1-diphenyl-2-picryl hydrazyl) method, vitamin C using as a positive control. Compound 1 has an IC50 value of 6.751 ppm while the value of IC50 for vitamin C was 2,98 ppm, so the compound is not an active antioxidant compounds.  Key words: Mangifera casturi, Antioxidant, triterpenoidÂ