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All Journal HAYATI Journal of Biosciences Majalah Kedokteran Bandung Global Medical and Health Communication Journal of Mechanical Engineering Education (Jurnal Pendidikan Teknik Mesin) AJER : Advanced Journal of Education and Religion
Agung Novianto, Agung
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Religion Agriculture, Biological Sciences & Forestry Humanities Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Mechanical Engineering Medicine & Pharmacology Nursing Public Health Other

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RELEVANSI MATERI MATA KULIAH KEAHLIAN OTOMOTIF DENGAN MATERI MATA PELAJARAN KOMPETENSI KEAHLIAN TEKNIK KENDARAAN RINGAN TERHADAP MATERI UJI KOMPETENSI KEAHLIAN STANDAR BSNP Novianto, Agung; Suherman, Amay; Ariyano, Ariyano
Journal of Mechanical Engineering Education Vol 2, No 1 (2015): Juni
Publisher : Universitas Pendidikan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.17509/jmee.v2i1.1149

Abstract

Tujuan penelitian ini adalah untuk mengetahui relevansi materi MKK otomotif dengan materi mata pelajaran kompetensi keahlian teknik kendaraan ringan (TKR), dan materi UKK BSNP. Objek dari penelitian ini adalah materi pembelajaran pada kurikulum DPTM UPI, kurikulum SMK, dan materi UKK BSNP. Penelitian ini menggunakan metode evaluasi model discrepancy. Instrumen yang digunakan berupa dokumentasi, lembar wawancara dan angket.  Hasil penelitian menunjukkan  bahwa Materi MKK otomotif telah relevan dan memenuhi keseluruhan  materi mata pelajaran kompetensi keahlian TKR sebanyak 173 materi, dan 130 materi UKK TKR I, II, dan III. Materi mata pelajaran kompetensi keahlian TKR SMK telah memenuhi materi UKK paket I dan II, namun belum memenuhi materi UKK TKR paket III, sebanyak 10 materi.
Cytotoxicity of Combination Doxorubicin and Garcinia picrorrhiza Fruit Extract on Fibroblast Cell Utami, Sri; Endrini, Susi; Batubara, Lilian; Rahmah, Nunung Ainur; Syarif, Irfan; Nafik, Said; Arrahmani, Betharie Cendera; Novianto, Agung; Kusuma, Hanna Sari Widya; Widowati, Wahyu
Global Medical & Health Communication (GMHC) Vol 11, No 3 (2023)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v11i3.10985

Abstract

Combining chemotherapeutic agents such as doxorubicin with herbal products or other compounds that can enhance cytotoxicity without side effects is required. Thus, we aimed to observe the cytotoxicity of doxorubicin and sesoot (Garcinia picrorrhiza) fruit ethanolic extract (GpKar) on human fibroblast cells, BJ. This study used a post-test-only control randomized group design with n=3 and a number group of 5. The method used in this research is cell number, and viability was measured with (3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium assay. Treatments consisted of a combination of doxorubicin (0.02 μg/ml) and GpKar of 66.47 µg/ml (DES1), 132.94 µg/ml (DES2) and 265.89 μg/ml (DES3). The data were analyzed using a one-way ANOVA and Duncan post hoc tests. DES3 showed the lowest viability among treatments (89.32%). DES1 and DES2 showed high viability (>90%), 97.93%, and 95.08%, respectively. Thus, the combination of doxorubicin (0.02 μg/ml) and GpKar (66.47 µg/ml) was considered safe for further use in the following assay. In summary, the combination of doxorubicin and GpKar showed high viability in normal fibroblast cells.
Potential of Clitoria ternatea L. Extract Towards Insulin Receptor Expression and Marker of Inflammation in Diabetes Mellitus Rats Model Rusmana, Djaja; Tiono, Hartini; Widowati, Wahyu; Lucianus, Johan; Darsono, Lusiana; Onggowidjaja, Philips; Tjokropranoto, Rita; Vera, Vera; Setiabudi, Edwin; Obeng, Selonan; Kusuma, Hanna Sari Widya; Novianto, Agung
HAYATI Journal of Biosciences Vol. 31 No. 4 (2024): July 2024
Publisher : Bogor Agricultural University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.4308/hjb.31.4.803-810

Abstract

Metabolic abnormalities caused by the accumulation of human, environmental, genetic and lifestyle variables can be found in diabetes mellitus (DM). An increase in blood glucose carried on by a reduction in insulin production can also result in DM. Insulin resistance often occurs as a result of obesity and a lack of physical activity and aging. Telang flower extract (Clitoria ternatea L.) is reported to have several qualities such as being able to treat DM, chronic bronchitis, goiter, mucosal disorders and leprosy. This study’s objective was to elucidate anti-dibetic effect of C. ternatea extract (CTE) in rats with diabetic complications related to dyslipidemia. Rats suffering from diabetes will be examined after being given oral doses of Simvastatin 0.9 mg/kg BW, Glibenclamide 0.45 mg/kg BW, and 200, 400, and 800 mg/kg BW CTE, model induced by streptozotocin. The expression of the insulin gene (INS-1) was investigated by qRTPCR, Tumor Necrosis Factor-α (TNF-α), and Interleukin-1β (IL-1β) pancreatic DM rats model using the Immunohistochemistry (IHC) test. Both descriptive and quantitative data were acquired for the data. After utilizing ANOVA to evaluate quantitative data, the Tukey post hoc test was used to analyze the data, the expression of TNF-α and IL-1β was found to decrease while INS-1 expression increased in response to CTE. This effect was attributed to the modulation of TNF-α, IL-1β, and INS-1 expression. These findings suggest that CTE possesses antidiabetic properties.
Utilization of Electronic Learning Media to Support the Professionalism of Islamic Religious Education Teachers at SMP Negeri 1 Babat Novianto, Agung; Ernanda, Eka Amalia; Puspita Sari, Rizka Ananda; Yurokhim, Ahmad Mahfudho
AJER: Advanced Journal of Education and Religion Vol 1 No 1 (2024): Januari
Publisher : Advance Journal of Education and Religion (AJER) published by Fakultas Agama Islam Universitas Islam Darul 'Ulum Lamongan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52166/ajer.v1i1.5550

Abstract

The advancement of electronics has grown and permeated various fields, including education. Electronic media can facilitate teachers in carrying out their profession, particularly in the case of Islamic Education teachers (PAI). Moreover, PAI lessons are considered tedious by a significant portion of school students. Most teachers rely solely on lecturing methods during the teaching process. One way to address this issue is by harnessing electronic learning media during the instructional process, especially for challenging topics students find difficult to grasp. This approach aims to spark students' interest in the subject matter. The objectives of this research are as follows: (1) to understand the perception of Islamic Education teachers regarding the benefits of electronic learning media, (2) to determine the utilization of electronic learning media at SMP Negeri 1 Babat (a public junior high school), and (3) to identify the supporting factors for the utilization of electronic learning media at SMP Negeri 1 Babat. The research employs a qualitative approach with a descriptive research design. Data collection techniques encompass interviews, observations, and documentation. The gathered data are analyzed through data reduction, presentation, and conclusion. The outcomes of this study reveal that: (1) All Islamic Education teachers comprehend the benefits of electronic learning media. (2) Among the four Islamic Education teachers at SMP Negeri 1 Babat, one teacher struggles to employ electronic learning media due to skill limitations. (3) The supportive factors for the utilization of electronic learning media at SMP Negeri 1 Babat include teachers' abilities, facilities and infrastructure, student readiness, and support from the school administration.
Antioxidant and Antimicrobial Potential of Sappan Wood Extract against Porphyromonas gingivalis Sugiaman, Vinna Kurniawati; Jeffrey, Jeffrey; Widowati, Wahyu; Ferdiansyah, Rival; Novianto, Agung
Majalah Kedokteran Bandung Vol 56, No 2 (2024)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15395/mkb.v56.3323

Abstract

Gingivitis inflammation triggered by microbial biofilms is one of the detrimental causes of periodontal diseases. When a periodontal disease occurs, tooth decay becomes inevitable, and can pose a serious threat to oral health, requiring appropriate treatment. Inflammation in periodontitis is mainly caused by oxidative stress; hence, antimicrobial and antioxidant-based therapies are suggested for periodontitis. Sappan wood is well-known for its brazilin compounds, which have the potential as herbal medicines and antibacterial agents to fight oral pathogens with minimal side effects. This study aimed to examine the antimicrobial and antioxidant activities of sappan wood extract (SE) as a candidate agent for preventing periodontal diseases. This study was conducted at Maranatha Christian University, Sekolah Tinggi Farmasi Indonesia, and Aretha Medika Utama from January-April 2023. The sappan wood was extracted using ethanol 96% and the antimicrobial evaluation was done by calculating the total colony of P. gingivalis while the antioxidant activity was evaluated by ABTS, H2O2, and FRAP Assays. This study revealed that SE was significantly effective in reducing the total colony of P. gingivalis up to 0 CFU/mL. The highest antioxidant activity of SE was found in 100 µg/mL with IC50 19.06 µg/mL for ABTS, 90.99 µg/mL for H2O2, and 564 µM Fe (II) for FRAP. Thus, SE presents its strong antimicrobial and antioxidant activity potentials by in vitro evaluation that could be analyzed further for its utilization as a periodontal-preventing agent. This study also provides basic information for future implication of sappan wood extract as ingredients for dental care products.
Co-Authors Amay Suherman Ariyano Ariyano, Ariyano Arrahmani, Betharie Cendera Batubara, Lilian Djaja Rusmana Edwin Setiabudi Ernanda, Eka Amalia Ferdiansyah, Rival Hanna Sari Widya Kusuma, Hanna Sari Widya Hartini Tiono Irfan Syarif, Irfan Jeffrey ., Jeffrey Johan Lucianus Lusiana Darsono Nafik, Said Nunung Ainur Rahmah Obeng, Selonan Philips Onggowidjaja Puspita Sari, Rizka Ananda Rita Tjokropranoto Sri Utami Susi Endrini vera vera, vera Vinna Kurniawati Sugiaman, Vinna Kurniawati WAHYU WIDOWATI Yurokhim, Ahmad Mahfudho