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All Journal Majalah Kedokteran Bandung Zenit Science and Technology Indonesia Jurnal Kedokteran Gigi Universitas Padjadjaran Padjadjaran Journal of Dentistry Oceana Biomedicina Journal E-Prodenta Journal of Dentistry MDJ (Makassar Dental Journal) SWARNA Cakradonya Dental Journal Indonesian Journal of Dentistry

Vinna Kurniawati Sugiaman, Vinna Kurniawati

Unknown Affiliation

Author-ID : 648248

Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Dentistry Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Nursing Physics Public Health

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Manfaat Keasaman Yoghurt dalam Pencegahan Karies Gigi Sugiaman, Vinna Kurniawati
Zenit Vol 3, No 2 (2014)
Publisher : Zenit

Show Abstract | Download Original | Original Source | Check in Google Scholar

Dental caries is a dental and oral health problem that is dominant in our country regardless of age, race, or the state of the economy. Therefore, we need to have a preventive measure to reduce the caries index that aims to enhance the standard of living by extending the usefulness of the teeth in the mouth.One of the actions to prevent the formation of dental caries is consuming yoghurt that contains probiotics and has the ability to improve the overall body health and oral health, such as dental caries, periodontitis, and halitosis.Probiotics can prevent and reduce the occurance of dental caries that works directly on the Streptococcus mutans as cariogenic bacteria to prevent its growth through several mechanisms that produce antimicrobial substances, bound in the oral cavity, immunomodulatory, and modify the conditions of the oral cavity. With a preventive action against dental caries,it is expected that in the future the classical problems of oral health such as dental caries is just a history.Keywords: dental caries, preventif, yoghurt

Utilization of Mesenchymal Stem Cells in Therapy in the Oral Cavity Sugiaman, Vinna Kurniawati
Oceana Biomedicina Journal Vol 2, No 2 (2019): Oceana Biomedicina Journal
Publisher : Universitas Hang Tuah

Terapi dengan memanfaatkan sel punca belakangan ini dianggap menjadi terobosan ilmiah untuk dunia kedokteran dan kedokteran gigi, serta dianggap sebagai senjata penting dalam memerangi berbagai macam penyakit. Sel punca mesenkimal merupakan sel yang memiliki kemampuan untuk memperbaharui dirinya sendiri, bersifat multipoten, mampu berdiferensiasi dan berproliferasi, serta bersifat immunosupresif, sehingga dapat dimanfaatkan dalam memperbaiki dan meregenerasi berbagai jaringan melalui terapi regenerative.Tujuan dari makalah ini adalah untuk memberikan gambaran singkat mengenai berbagai sumber sel punca dan temuan terbaru serta implikasinya untuk meningkatkan kesehatan rongga mulut melalui regenerasi berbagai jaringan di rongga mulut. Pemanfaatan sel punca mesenkimal di bidang kedokteran gigi dianggap bahwa era baru kedokteran gigi sedang dimulai dan diharapkan dapat merubah paradigma dalam melakukan perawatan terhadap penyakit di rongga mulut. Sel punca mesenkimal dapat diisolasi dari berbagai jaringan yang dapat digunakan dalam terapi regenerative melalui teknologi rekayasa jaringan untuk memperbaiki dan meregenerasi jaringan di rongga mulut. Pada pemanfaatan teknologi ini, diperlukan sel punca, regulator, dan matriks sebagai kerangka yang dapat memfasilitasi sel untuk melekat, berdiferensiasi, berproliferasi, membentukan matriks, dan meningkatkan interaksi spesifik antar sel.Simpulan, sel punca mesenkimal dapat dimanfaatkan dalam terapi regenerative di rongga mulut untuk memperbaki dan meregenerasi jaringan yang rusak melalui teknologi rekayasa jaringan. Kata kunci: sel punca mesenkimal; terapi regenerative; teknologi rekayasa jaringan

Efek Antibakteri Ekstrak Etanol Bunga Telang (Clitoria ternatea) terhadap Bakteri Porphyromonas gingvivalis Sinaga, Nadya Atalia; Kurnia, Calvin; Sugiaman, Vinna Kurniawati
E-Prodenta Journal of Dentistry Vol 8 No 1 (2024)
Publisher : Fakultas Kedokteran Gigi UB

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.eprodenta.2024.008.01.2

Pendahuluan: Periodontitis merupakan penyakit inflamasi yang disebabkan oleh infeksi jaringan pendukunggigi. Salah satu bakteri yang terdapat dalam penyakit periodontitis adalah Porphyromonas gingivalis (P.gingivalis) yang dapat menghancurkan jaringan pendukung gigi. Bunga telang (Clitoria ternatea) memilikikandungan biologi aktif seperti flavonoid, saponin, steroid, triterpenoid, dan tanin yang memiliki sifatantibakteri, antioksidan, antidiabetes, dan antiinflamasi. Tujuan: untuk mengetahui efek antibakteri ekstraketanol bunga telang terhadap P. gingivalis. Metode: Penelitian ini menggunakan metode difusi cakram padamedia Mueller Hinton Agar (MHA) yang dibagi menjadi 9 kelompok perlakuan, kemudian dilakukan pengukurandiameter zona hambat menggunakan jangka sorong. Analisis statistik pada penelitian ini dilakukanmenggunakan Analisys of Vanians (ANOVA). Hasil: rata-rata daya hambat pertumbuhan P. gingivalis tertinggipada kelompok kontrol positif sebesar 27,70mm dan berbeda signifikan dengan daya hambat pada konsentrasi25%, 50%, 75%, dan 100%. Rata-rata tertinggi kedua terjadi pada kelompok dengan konsentrasi 100%sebesar 23,70%, diikuti berturut-turut oleh kelompok dengan konsentrasi 75% sebesar 19,47mm, konsentrasi50% sebesar 16,72% dan konsentrasi 25%. Kesimpulan: ekstrak etanol bunga telang (Clitoria ternatea)dapat menghambat pertumbuhan P. gingivalis pada konsentrasi 100% dengan hasil rata-rata diameter zonahambat sebesar 23,067%.

Antibacterial effects of tomato ethanol extract (Solanum lycopersicum L.) against S. mutans and P. gingivalis: a laboratory experiment Rahmawati, Dicha Yuliadewi; Kurniawan, Viola Febi; Sanjaya, Oei Tirza Cintya; Sugiaman, Vinna Kurniawati; Mandalas, Henry Yonatan
Padjadjaran Journal of Dentistry Vol 35, No 3 (2023): November 2023
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/pjd.vol35no3.50582

ABSTRACT Introduction: Process of dental plaque formation consists of three stages, pellicle formation, initial colonization facultative gram-positive one of microbes is S. mutans, secondary colonization and microbial maturation by Porphyromonas intermedia, P. gingivalis, Fusobacterium nucleatum. Formation of dental biofilm is considered to be main etiology of chronic periodontitis. Bacteria that often involved in chronic periodontitis are P. gingivalis. Tomatoes (Solanum lycopersicum L.) content lycopene compounds, flavonoids, and saponins have been shown to inhibit or kill bacterial growth. The aim is to analyze the antibacterial effect of servo tomato ethanol extract against S. mutans and P. gingivalis. Methods: This research was a laboratory experimental one with a posttest only control group design where observed variable diameter of the inhibition zone was produced from ethanolic extract of tomato (Solanum lycopersicum L.) in various concentrations of 3.125, 6.25, 12.5, 25, 50 and 100% chlorhexidine 0.2% as a positive control, negative control of distilled water against S. mutans and P. gingivalis on blood agar media. The method used in this study was the well-diffusion test. Results: The highest inhibitory zone at 100% concentration with a diameter of 32.10 mm was very strong; lowest inhibition at 3.123% was 3.95 mm, weak classification and against P. gingivalis at 3.125%, it was 3.72 mm, weak classification, meanwhile at 100% concentration, it was 9.67 mm, medium classification. The results of the One Way ANOVA statistical test showed a p<0.05 which had a significant effect in inhibiting the growth of S. mutans and P. gingivalis. Conclusions: There was an antibacterial effect of the ethanolic extract of tomato against S.mutans produced a larger diameter and stronger inhibition zone meanwhile against P.gingivalis produce medium inhibition zone. The content of tomatoes such as lycopene compounds, flavonoids, and saponins have been shown to inhibit or kill bacterial growth.Keyword : tomato ethanol extract (Solanum lycopersicum L.), S. mutans, P. gingivalis, antibacterial

Differences in salivary acidity before and after consumption of sugary drinks in children of Ra Hudallah Kujangsari Village, Langensari Subdistrict, Banjar City: Perbedaan derajat keasaman saliva sebelum dan sesudah konsumsi minuman manis pada anak-anak Ra Hudallah Desa Kujangsari Kecamatan Langensari Kota Banjar Mellinia, Patricia Octaviane; Zalzamitha, Tifanny; Posumah, Gabriela Lestari Natalya; Sinaga, Nadya Atalia; Setiawan, Ignatius; Laksmi, Primarizka Iswara; Sugiaman, Vinna Kurniawati
Makassar Dental Journal Vol. 13 No. 3 (2024): Volume 13 Issue 3 Desember 2024
Publisher : Makassar Dental Journal PDGI Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35856/mdj.v13i3.1112

This study aims to determine the effect of sugary drinks on the pH value of saliva in children, is an analytical observation with expe-rimental methods regarding the relationship of sugary drinks to the pH value of saliva measured using a pH meter. The research was conducted at RA Hudallah Kujangsari Village, Langensari Subdistrict, Banjar City. The results showed that before drinking sugary drinks, the majority of children had a normal pH category (64%), while after drinking sugary drinks, the pH state changed to be more acidic (70%) and only 22% had a normal pH category. It was concluded that after drinking sugary drinks, 78% expe-rienced a significant decrease in salivary pH, the rest had a normal pH.

Antioxidant and Antimicrobial Potential of Sappan Wood Extract against Porphyromonas gingivalis Sugiaman, Vinna Kurniawati; Jeffrey, Jeffrey; Widowati, Wahyu; Ferdiansyah, Rival; Novianto, Agung
Majalah Kedokteran Bandung Vol 56, No 2 (2024)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15395/mkb.v56.3323

Gingivitis inflammation triggered by microbial biofilms is one of the detrimental causes of periodontal diseases. When a periodontal disease occurs, tooth decay becomes inevitable, and can pose a serious threat to oral health, requiring appropriate treatment. Inflammation in periodontitis is mainly caused by oxidative stress; hence, antimicrobial and antioxidant-based therapies are suggested for periodontitis. Sappan wood is well-known for its brazilin compounds, which have the potential as herbal medicines and antibacterial agents to fight oral pathogens with minimal side effects. This study aimed to examine the antimicrobial and antioxidant activities of sappan wood extract (SE) as a candidate agent for preventing periodontal diseases. This study was conducted at Maranatha Christian University, Sekolah Tinggi Farmasi Indonesia, and Aretha Medika Utama from January-April 2023. The sappan wood was extracted using ethanol 96% and the antimicrobial evaluation was done by calculating the total colony of P. gingivalis while the antioxidant activity was evaluated by ABTS, H2O2, and FRAP Assays. This study revealed that SE was significantly effective in reducing the total colony of P. gingivalis up to 0 CFU/mL. The highest antioxidant activity of SE was found in 100 µg/mL with IC50 19.06 µg/mL for ABTS, 90.99 µg/mL for H2O2, and 564 µM Fe (II) for FRAP. Thus, SE presents its strong antimicrobial and antioxidant activity potentials by in vitro evaluation that could be analyzed further for its utilization as a periodontal-preventing agent. This study also provides basic information for future implication of sappan wood extract as ingredients for dental care products.

Efek Antibakteri Formulasi Sediaan Pasta Gigi Ekstrak Teh Hijau (Camellia sinensis L.) dan Peppermint (Mentha piperita L.) Terhadap Streptococcus mutans Sugiaman, Vinna Kurniawati; Pradipta, Regina; Widowati, Wahyu
Cakradonya Dental Journal Vol 17, No 1 (2025): Februari 2025
Publisher : FKG Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/cdj.v17i1.34721

Streptococcus mutans merupakan bakteri yang bersifat asidogenik dan kariogenik yang berperan sebagai agen etiologi dalam pembentukan karies. Pemilihan pasta gigi yang mengandung bahan herbal merupakan salah satu upaya dalam pencegahan karies. Kombinasi ekstrak teh hijau dan peppermint dapat digunakan sebagai formulasi sediaan pasta gigi karena memiliki sifat antibakteri. Tujuan penelitian ini adalah mengetahui efek antibakteri sediaan pasta gigi ekstrak teh hijau (Camellia sinensis L.) dan peppermint (Mentha piperita L.) terhadap S. mutans. Penelitian ini menggunakan metode difusi cakram, terdapat empat kelompok perlakuan yang diuji yaitu pasta gigi ekstrak teh hijau dan peppermint dengan konsentrasi 1000 mg/ml, 500 mg/ml, 250 mg/ml, 125 mg/ml, 62,5 mg/ml, dan 31,25 mg/ml, pasta gigi base, pasta gigi herbal sebagai kontrol positif, dan NaCl 0,9% sebagai kontrol negatif. Hasil pengukuran diameter zona hambat terkecil didapatkan pada konsentrasi 125mg/ml dengan diameter zona hambat rata-rata sebesar 6,31 mm sedangkan zona hambat terbesar berada pada konsentrasi 1000 mg/ml dengan diameter zona hambat rata-rata sebesar 11,43 mm. Kesimpulan dari penelitian ini adalah pasta gigi ekstrak teh hijau dan peppermint memiliki efek antibakteri terhadap Streptococcus mutans.

Viability of fibroblast cells on the clove (Syzygium aromaticum) leaves ethanol extract Felicia, Anindhita Cindy; Sugiaman, Vinna Kurniawati; Pranata, Natallia
Padjadjaran Journal of Dentistry Vol 31, No 1 (2019): March 2019
Publisher : Universitas Padjadjaran

Introduction: Various active compounds of herbal plants that are known to accelerate the wound healing process are flavonoids, tannins, and saponins. One amongst them is clove (Syzygium aromaticum), with the leaves as the most common part to be used as herbal medicine due to the antibacterial, anti-inflammatory, and antioxidant properties. However, the use of the biocompatibility of clove leaves as herbal medicine is still unknown. Therefore, this study was aimed to determine the cytotoxicity effects of clove leaves ethanol extract on the fibroblast cells and safe dosage (IC50) for medicinal use. Methods: Phytochemical tests using the Farnsworth method and viability test was performed using the laboratory experimental with post-test only control group design. The samples were divided into seven concentrations; 500, 250, 125, 62.5, 31.25, 15.63, and 7.81 μg/ml, with three repetitions (triplo) towards the fibroblast cells. Viability test was performed using MTS assay. Results: Based on the results obtained from one-way ANOVA statistical test, there was a significant difference between the percentage of cell viability and each concentration (α ≤ 0.05), with IC50 value of 344.814 μg/ml. Conclusion: Clove (Syzygium aromaticum) leaves ethanol extract showed a high percentage of cell viability at the concentrations below the IC50 value.Keywords: Clove leaves, cytotoxicity, fibroblast cell, MTS assay, periodontal diseases, viability.

The effect of Indian jujube leaves extract in inhibiting the growth of Porphyromonas gingivalis Pratiwi, Gracia Yodianvi; Mandalas, Henry Yonatan; Sugiaman, Vinna Kurniawati
Padjadjaran Journal of Dentistry Vol 34, No 1 (2022): March
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/pjd.vol34no1.33007

Introduction: Periodontitis is an inflammatory disease that destroys tooth-supporting tissues and is associated with increased risk factors for systemic diseases. The main pathogen of periodontitis is the bacteria P. gingivalis, a Gram-negative, anaerobic, pleomorphic, coccobacillus, non-motile, and saccharolytic. The leaves of Indian jujube (Ziziphus mauritiana Lam.) have the main bioactive compounds such as saponins, tannins, and flavonoids which have antimicrobial activities against pathogenic microorganisms. This study aims to analyse various concentrations of the ethanol extract of Indian jujube leaves against P. gingivalis. Methods: The method used in this study was the disc diffusion test based on the Clinical and Laboratory Standard Institute. P. gingivalis preparation and the fresh leaves of Indian jujube collected from one of the plantations in Probolinggo, East Java. In this study, tests used various concentrations of Indian jujube leaves extract, namely 10, 20, 30, 40, 50, 60, 70, 80, 90, and 100%. Data antibacterial activity was classified according to David and Stout’s inhibition zone classification. Results: Indian jujube leaves extract with a concentration between 10-30% had weak antibacterial activity, 40-60% had moderate antibacterial activity, and 70-100% had strong antibacterial activity. The largest inhibitory zone diameter against P. gingivalis was found at a concentration of 100%. Conclusion: Indian jujube leaves extract starting from a concentration of 70% can inhibit the growth of P. gingivalis with strong antibacterial activity.

PENERAPAN EDUKASI GIZI SEIMBANG BERBASIS EMPAT PILAR DAN ISI PIRINGKU BAGI ANAK-ANAK DI RUMAH RUTH BANDUNG Sugiaman, Vinna Kurniawati; Varensia, Ellyvia; Kristianti, Vivian Okta; Kristiawan, Sarah Parmashta; Christiane, Jesslyn Febe; Batuaji, Stefani Alphina; Saputra, Albertus Christian; Setiawan, Angelique Aprilla; Santoso, Chillie Aimeelita; Chriscendio, Felix
SWARNA: Jurnal Pengabdian Kepada Masyarakat Vol. 3 No. 11 (2024): SWARNA : Jurnal Pengabdian Kepada Masyarakat, November 2024
Publisher : LPPM Sekolah Tinggi Ilmu Ekonomi 45 Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55681/swarna.v3i11.1467

Kesehatan gigi dan mulut memegang peranan penting dalam menjaga kualitas hidup seseorang. Namun, pemahaman dan penerapan teknik menyikat gigi serta penggunaan benang gigi yang baik dan benar sering kali masih kurang, terutama di kalangan anak-anak. Penelitian ini bertujuan untuk memberikan edukasi mengenai teknik menyikat gigi dan penggunaan benang gigi kepada anak-anak di Panti Asuhan Putera Maranatha serta mengevaluasi keberhasilannya. Metode yang digunakan meliputi penyuluhan dengan demonstrasi langsung, pembagian materi edukasi visual, dan evaluasi. Evaluasi dilakukan melalui kuesioner pre-test dan post-test. Hasil penelitian menunjukkan peningkatan dalam pemahaman dan keterampilan anak-anak dalam menjaga kesehatan gigi dan mulut. Temuan ini menegaskan akan pentingnya program edukasi kesehatan gigi untuk meningkatkan kesadaran dan kebiasaan perawatan gigi sejak dini.

Co-Authors Agung Novianto, Agung Ahmad Faried Azis, Rizal Batuaji, Stefani Alphina Calvin Kurnia Chriscendio, Felix Christiane, Jesslyn Febe Didik Priyandoko Dwiarie, Theodora Adhisty Felicia, Anindhita Cindy Ferdiansyah, Rival Harry Murti Ignatius Setiawan, Ignatius Jeffrey ., Jeffrey Kristianti, Vivian Okta Kristiawan, Sarah Parmashta Kurniawan, Viola Febi Laksmi, Primarizka Iswara Mandalas, Henry Yonatan Manurung, Mian Maranata Br Mellinia, Patricia Octaviane Nainggolan, Ita Margaretha Natallia Pranata Pascharia, Theresia Imelda Posumah, Gabriela Lestari Natalya Pradipta, Regina Pratiwi, Gracia Yodianvi Qlintang, Sandy RAHMAT, DENI Rahmawati, Dicha Yuliadewi Sanjaya, Oei Tirza Cintya Santoso, Chillie Aimeelita Saputra, Albertus Christian Setiawan, Angelique Aprilla Sinaga, Nadya Atalia Teresa Liliana Wargasetia Triharsiwi, Dwi Nur Varensia, Ellyvia WAHYU WIDOWATI Zalzamitha, Tifanny

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