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All Journal Journal of Food and Pharmaceutical Science Media Ilmu Kesehatan Jurnal Mandala Pharmacon Indonesia Cendekia Journal of Pharmacy Jurnal Surya Masyarakat Journal of Innovation in Community Empowerment (JICE) Jurnal Farmasi Sains dan Praktis Journal of Biotechnology and Natural Science Journal of Pharmaceutical (JOP) Journal of Food and Pharmaceutical Sciences Bencoolen Journal of Pharmacy
Endah Kurniawati
Universitas Jenderal Achmad Yani Yogyakarta, Indonesia
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Engineering Environmental Science Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences

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Edukasi Pengelolaan Stres Sebagai Upaya menjaga Kesehatan Kulit Rizqa Salsabila Firdausia; Endah Kurniawati; Mufrod
The Journal of Innovation in Community Empowerment Vol 5 No 1 (2023): Journal of Innovation in Community Empowerment (JICE)
Publisher : Universitas Jenderal Achmad Yani Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30989/jice.v5i1.814

Abstract

ABSTRACT Stress is a problem that often arises in this modern era. Stress can be acute or chronic and is determined by individual perceptions and the body's response to the pressure. Long-term exposure to continuous stress can lead to physical illness in the body (psychosomatic), one of them is skin. Unhealthy skin will also cause a decrease in self-confidence, causing stress. Therefore there is a need for psychotherapeutic intervention to overcome these disorders and to restore the body's condition. Strategies that can be done to deal with stress can include an active approach to the source of stress, seeking social support (emotional support or information from other people or seeing a psychologist) from the surrounding environment, building self-control (self-control) towards the source of the problem, as well as trying to find a positive side from stress. So that this service activity is expected to be able to educate the public, especially teenagers to be able to manage stress properly. The activity was carried out using the webinar method with 37 youth participants. The activity was carried out in 3 stages, namely pretest, limitation of material - discussion and post test. In the pretest and posttest stages the participants were given the same 5 questions. Based on the results of the pretest and posttest, it was found that there was an increase in the correct answers from 79.459% to 85.405%. This indicates that there is an increase in knowledge from the participants related to managing stress on skin health after the intervention. Based on this, it can be interpreted that community service activities with the theme "Stress Management Education as an Effort to Maintain Skin Health" can be carried out properly and increasing knowledge of participant.
Analisis Kandungan Sibutramin HCl pada Jamu Pelangsing dengan Metode Spektrofotometri UV-Vis Kholif, Kholif Sholehah Indra K; Kurniawati, Endah; Komalasari, Desy
JOURNAL OF PHARMACEUTICAL (JOP) Vol. 2 No. 2 (2024): Journal of Pharmaceutical (JOP)
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat (LPPM) UNIVERSITAS JENDERAL ACHMAD YANI YOGYAKARTA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30989/jop.v2i2.1459

Abstract

Background: Plant, mineral, animal, extract (galenic) preparations, or a combination of various ingredients form the basis of jamu, a type of traditional herbal medicine. Herbal medicine has been applied in treatment based on experience, where its benefits and safety have been proven empirically. One type of herbal medicine popular with the public, especially women, is slimming herbal medicine. As the demand for slimming herbal medicine increases, some parties capitalize on this trend by adding medicinal chemicals (BKOs). Sibutramine HCl is a commonly added BKO in slimming herbal medicine. Objective: To qualitatively and quantitatively analyze the sibutramine HCl content in herbal slimming powders circulating in the Yogyakarta city market. Method: This type of research is non-experimental descriptive with a purposive sampling technique. The samples used in this research were 10 herbal slimming powders with various brands circulating in the Yogyakarta City market. Sample analysis was carried out qualitatively using the Thin Layer Chromatography method and wavelength scanning. Meanwhile, quantitative analysis was carried out using UV-Vis Spectrophotometry. Results: The results of qualitative and quantitative sample analysis showed that from 10 samples, 2 samples were positive for containing sibutramine HCl in samples A and B. The sibutramine HCl content in sample A was 2,4377 ± 0,0066%w/w and B was 1,0164 ± 0,0114%w/w. Conclusion: There is BKO sibutramine HCl content in the powdered slimming herbal medicine samples with respective levels of 2,4377 ± 0,0066%w/w and 1,0164 ± 0,0114%w/w.
Formulation and Sunscreen Activity Assay of Fig Fruit (Ficus carica L.) Extract Cream Kurniawati, Endah; Firdausia, Rizqa Salsabila; Sari, Kurnia Rahayu Purnomo
MEDIA ILMU KESEHATAN Vol 14 No 1 (2025): Media Ilmu Kesehatan
Publisher : Universitas Jenderal Achmad Yani Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30989/mik.v14i1.1472

Abstract

Background: Ultraviolet radiation can cause skin damage and increase the cancer risk. Sunscreen provides skin protection against UV. Cream is one of the popular sunscreen dosage form. The increasing demand of natural resources such as fig fruit is caused by its potential ability as sunscreen.Objective: The aim of this study is to evaluate the sunscreen ability of fig fruit extract and to evaluate the impact of extract concentration variation towards cream physical properties.Methods: Sunscreen activity of extracts were determined by SPF value and IC50. The sunscreen formulation consist of three variation of extract concentration (10%, 15%, 20%). Cream were measured for the SPF value and the physical properties. Results: Fig fruit extract (12500 ppm) had the SPF value namely 29,64 and IC50 value of 948,69 ppm. The SPF value of cream with 10% ; 15% ; 20% concentration respectively were 2,1 ; 5,25 ; 7,74. All cream formulation had good physical properties. Cream F3 had the best stability after 1 month storage. Conclusion: Significant correlation was found between SPF value and concentration of extract in cream. But no significant correlation was found between concentration of extract and physical properties of cream
Formulasi Krim dan Analisa Potensi Antioksidan dari Fraksi Ekstrak Etanol Bawang Hitam Firdausia, Rizqa Salsabila; Kurniawati, Endah; Rusydan, Azka Muhammad; Ardianto, Lisman Septa
MEDIA ILMU KESEHATAN Vol 14 No 1 (2025): Media Ilmu Kesehatan
Publisher : Universitas Jenderal Achmad Yani Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30989/mik.v14i1.1476

Abstract

Background: Reactive oxygen species (ROS) are free radicals that can cause damage to skin tissue. ROS can be prevented by antioxidants in plants that contain phenolics and flavonoids such as in black garlic. To obtain more specific compounds, fractionation of black garlic extract was carried out using polar, semi-polar and non-polar solvents. Objective: This study aims to determine the antioxidant activity by the FRAP method, then make and evaluate cream products from fractions of black garlic ethanol extract. Methods: Black garlic is made by heating garlic using a rice cooker, then extracted by maceration method. The resulting extract was fractionated with 3 solvents namely water, ethyl acetate and n-hexane. Furthermore, phytochemical screening and antioxidant analysis with the FRAP method were conducted. Fractions with the highest antioxidant activity were formulated into 3 cream preparations with extract concentrations of 0.5; 1; 1.5% and evaluated.Results: The water fraction had higher antioxidant ability, 1.545 ± 0.128 mmol/g extract. The water fraction was then developed into a cream preparation and evaluated the physical properties of the three formulas.Conclusion: Based on the test results, the three cream formulas have good physical properties and are stable at room and low temperatures.
Edukasi penggunaan antibiotik untuk mencegah resistensi Kurniawati, Endah; Sari, Kurnia Rahayu Purnomo; Tenabolo, Vilkanova Asenath Inna
The Journal of Innovation in Community Empowerment Vol 7 No 1 (2025): Journal of Innovation in Community Empowerment (JICE)
Publisher : Universitas Jenderal Achmad Yani Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30989/jice.v7i1.1435

Abstract

Resistensi antimikroba khususnya antibiotik merupakan masalah kesehatan yang terjadi secara global. Keberadaan resistensi ini dapat menyebabkan ketidakefektifan dari antibiotik yang diberikan. Jika individu tidak menghabiskan antibiotik yang diberikan maka bakteri tersebut akan berkembang dan membangun resistensi terhadap antibiotik tersebut. Resistensi sendiri merupakan suatu proses yang alami terjadi seiring dengan perubahan genetik yang terjadi pada patogen/mikroba. bakteri tersebut akan berkembang dan membangun resistensi terhadap antibiotik tersebut Namun penggunaan antibiotik yang tidak tepat dan berlebihan dapat mempercepat tingkat kejadian resistensi tersebut. Kegiatan pengabdian ini dimaksudkan untuk memberikan edukasi agar masyarakat lebih bijak menggunakan antibiotik. Kegiatan pengabdian ini melibatkan 19 peserta dari Padukuhan Barongan, Sumberagung, Jetis, Yogyakarta. Berdasarkan hasil evaluasi pretest dan posttest, peserta mengalami peningkatan pemahaman mengenai penggunaan antibiotik dari 93% menjadi 100%. Peserta memiliki pemahaman awal yang baik. Adanya peningkatan pemahaman antara pretest dan posttest tersebut menjadi petunjuk bahwa kegiatan ini bermanfaat meningkatkan pengetahuan masyarakat terkait penggunaan antibiotik yang rasional. Kegiatan ini berjalan lancar dengan antusiasme yang luar biasa dari para peserta selama kegiatan
Optimasi Waktu Ekstraksi Dengan Metode Ultrasound Assisted Extraction (UAE) Terhadap Kandungan Senyawa Flavonoid dan Fenolik Daun Kayu Bulan (Pisonia alba Span.) Firdausia, Rizqa Salsabila; Pratama, Nofran Putra; Kurniawati, Endah; Ervany, Irrena; Wibisono, Dika Irawan; Rikhaturhohmah, Rikhaturhohmah; Ardianto, Lisman Septa
Jurnal Mandala Pharmacon Indonesia Vol. 11 No. 1 (2025): Jurnal Mandala Pharmacon Indonesia
Publisher : Program Studi Farmasi Universitas Mandala Waluya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35311/jmpi.v11i1.715

Abstract

Daun kayu bulan (Pisonia alba Span.) merupakan tanaman hias yang diketahui memiliki kemanfaatan sebagai antioksidan yang diperankan oleh metabolit sekunder antara lain flavonoid dan fenolik. Kedua senyawa tersebut dapat diperoleh dengan cara ekstraksi salah satunya dengan metode Ultrasound Assisted Extraction (UAE). Untuk mendapatkan senyawa yang diinginkan secara maksimal, diperlukan adanya suatu optimasi salah satunya terhadap waktu. Pada penelitian ini, ekstraksi sampel dilakukan dengan metode UAE menggunakan pelarut etanol 70% dengan variasi 6 waktu ekstraksi yaitu 15, 30, 45, 60, 75 dan 90 menit. Hasil ekstrak diuji terhadap kandungan flavonoid dan fenolik dengan metode KLT dan spektrofotometri UV-Vis. Berdasarkan analisa kualitatif dengan KLT diperoleh pada seluruh ekstrak mengandung senyawa flavonoid dan fenolik dengan nilai Rf 0,5875 dan 0,6375 secara berurutan. Pada analisa kuantitatif, adanya perbedaan pada kadar flavonoid dan fenolik dengan adanya perbedaan waktu ekstraksi. Waktu ekstraksi yang menghasilkan kadar tertinggi baik pada flavonoid maupun fenolik adalah 45 menit dengan kadar berturut-turut 6,345 ± 0,009 mg QE/gram dan 15,6438 ± 0,0199 mg GAE/gram. Dapat disimpulkan bahwa 45 menit merupakan waktu ekstraksi optimum ekstraksi daun kayu bulan dengan metode UAE.
The Influence of Dry Rendering and Ultrasonic?Assisted Extraction on DPPH Radical Scavenging Activity of Red Fruit (Pandanus conoideus) Arifah, Mitsalina Fildzah; Kurniasih, Kholif Sholehah Indra; Kurniawati, Endah; Erlinaningrum, Mustika; Melanie, Zaskia Nora
MEDIA ILMU KESEHATAN Vol 14 No 2 (2025): Media Ilmu Kesehatan
Publisher : Universitas Jenderal Achmad Yani Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30989/mik.v14i2.1471

Abstract

Background: Red fruit (Pandanus conoideus) is a source of antioxidant compound components. Extraction methods can affect the antioxidant activity of the red fruit oil (RFO). Dry rendering is often used in conventional oil extraction, but it can potentially degrade antioxidant components. Currently, ultrasonic-assisted extraction (UAE) is a modern, yet underexplored method for oil extraction.Objective: This study aims to compare the extraction method on the antioxidant activity of RFO. Methods: The extraction methods included dry rendering and ultrasound-assisted extraction (UAE) using water and n-hexane as solvents. The flavonoid and phenolic contents, percentage yield, and DPPH free radical scavenging antioxidant activity were evaluated in RFO.Results: The results showed that the % yield with dry rendering was higher than in the UAE. The three extracts showed the presence of flavonoids and phenolics based on FeCl3 and AlCl3 tests. The highest antioxidant activity was in the dry rendering method (0,13% w/v) compared to UAE-water (0,98% w/v) and UAE-n hexane (1,47% w/v). Dry rendering could separate bioactive compounds with the highest % yield and inhibit DPPH free radicals with high temperatures, and without solvents. Conclusion: The dry rendering was selected as the extraction method, resulting in higher yields and antioxidant compounds in EBM compared to UAE.
Co-Authors Amaliya, Siti Nur Ardianto, Lisman Septa Arifah, Mitsalina Fildzah Desy Komalasari Diah Pratimasari Dian Puspitasari Erlinaningrum, Mustika Ervany, Irrena Fajar Setyo Wibowo Kholif, Kholif Sholehah Indra K Kurniasih, Kholif Sholehah Indra Kurniawati, Siska Putri Melanie, Zaskia Nora Mufrod Mufrod Novena Yety Lindawati Oktapiya, Tira Risa Pratama, Nofran Putra Putri, Gita Herdittya Rikhaturhohmah, Rikhaturhohmah Rita Rusmeilina Rizqa Salsabila Firdausia Rusydan, Azka Muhammad Sari, Kurnia Rahayu Purnomo SEPTI WULANDARI Tenabolo, Vilkanova Asenath Inna Wibisono, Dika Irawan Widiani, Fitria Zulfaidah, Nanda Tsalasani