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All Journal Jurnal Profesi Medika: Jurnal Kedokteran dan Kesehatan Indian Journal of Forensic Medicine & Toxicology International Islamic Medical Journal AGRI-TEK : Jurnal Penelitian Ilmu-ilmu Eksakta Hang Tuah Medical Journal Medical and Health Journal Jurnal Kedokteran Meditek
Diah Purwaningsari
Faculty Of Medicine, Universitas Hang Tuah, Surabaya, Indonesia
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health

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The Effect Of Dawood's Fasting In Removing Total Blood Cholesterol Levels In Surabaya Hidayatullah Islamic Boarding School’s Student Rahayu, Indri Ngesti; Wijayanti, Ni Luh Putu Ratih; Purwaningsari, Diah; Komalasari, Intan; Dagradi, Eric Mayo
Jurnal Medis Islam Internasional Vol 3 No 1 (2021): December
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/iimj.v3i1.2445

Abstract

Background: Hypercholesterolemia is a risk factor for causing death at a young age. The World Health Organization reported in 2002 that 4.4 million deaths were caused by hypercholesterolemia, or 7.9% of the total number of deaths at a young age. Hypercholesterolemia is a condition in which cholesterol levels in the body exceed normal levels. One way that can be done to prevent hypercholesterolemia is to control diet, namely by fasting. Dawood’s fasting is one of the obligatory fasts of Islamwhich is done with one-day fasting and one-day not. Objective: This study aims to determine the effect of Dawood’s fasting in reducing total blood cholesterol levels in Hidayatullah Islamic Boarding School students in Surabaya.Methods: This study was designed with a quasi-experimental study research method using a comparative pre-test post-test non-equivalent control group design. The sample in this study was divided into two groups, namely one control group and one treatment group from the sample selected by purposive sampling. The population studied were students of the Hidayatullah Islamic Boarding School in Surabaya. Result: The results of statistical analysis using the Wilcoxon signed-rank test showed an effect of Dawood’s fasting in reducing total blood cholesterol levels in Hidayatullah Islamic Boarding School students in Surabaya.Conclusion: From research result that has been done, it can be concluded that there is an effect of Dawood’s fasting in reducing total blood cholesterol levels in Hidayatullah Islamic Boarding School students in Surabaya. Keywords: Dawood’s fasting, total blood cholesterol.
THE EFFECT OF ETHANOL EXTRACT OF Rhizophora mucronate LEAVES ON THE GROWTH OF Staphylococcus aureus BACTERIA Firda, Armadani Aisyah; Ardiana, Dian; Purwaningsari, Diah
Medical and Health Journal Vol 4 No 2 (2025): February
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.mhj.2025.4.2.14688

Abstract

Sebagian besar infeksi kulit di Indonesia disebabkan oleh bakteri Staphylococcus aureus yang bersifat patogen oportunistik dan bertanggung jawab atas permasalahan resistensi antibiotik Metisilin dan Vankomisin terhadap S.aureus. Daun bakau R. mucronata mengandung aktivitas antibakteri pada senyawa metabolit sekunder yakni fenol, flavonoid, saponin, tanin, dan terpenoid. Penelitian ini bertujuan untuk mengetahui pengaruh ekstrak etanol 96% daun bakau R. mucronata terhadap pertumbuhan bakteri Staphylococcus aureus. Penelitian dilakukan secara eksperimental laboratoris dengan sampel biakan murni Staphylococcus aureus murni, diambil dengan teknik random sampling, dicampur dengan aquades dan kekeruhannya setara dengan standarisasi 0,5 Mc Farland, ditanam di agar Mueller Hinton. Daun Bakau R. mucronata diekstraksi dengan metode maserasi dan dibuat 4 seri konsentrasi (25%, 50%, 75%, dan 100%). Uji antibakteri menggunakan metode difusi cakram dengan kontrol positif Siprofloksasin 5 mcg dan kontrol negatif akuades steril. Semua cawan petri dimasukkan kedalam inkubator selama 24 jam pada suhu 37°C, lalu diukur diameternya. Data dianalisis secara statistik dengan uji Nonparametrik Kruskal Wallis dan dilanjutkan uji posthoc Mann Whitney-U. Hasil penelitian menunjukkan peningkatan diameter zona hambat setiap konsentrasi ekstrak dengan aktivitas penghambatan tertinggi pada konsentrasi 100% sebesar 11,7 mm. Simpulan dalam penelitisn ini bahwa ekstrak etanol 96% daun bakau R. mucronata dapat menghambat pertumbuhan bakteri S.aureus secara in vitro
The Effect Of Ethanol Extract Of Golden Sea Cucumber (Stichopus Hermanii) On Alt Levels In Aspirin-Induced Wistar Male Rats (Rattus Norvegicus) Ferguszon, Devina Hanalily Maharani; Purwaningsari, Diah; Wienta Diarsvitri, Wienta; Poerwanto, Eka
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 19 No 1 (2025): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan (In Press)
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/jpm.v19i1.10386

Abstract

Drug-induced liver injury is the most common cause of acute liver failure in the United States. Hepatocyte injury can be caused by the consumption of high doses of aspirin, leading to the formation of free radicals. Golden sea cucumber (Stichopus hermanii) can play a role in prevention of free radicals through antioxidant. The study used a post test only control group design involving 32 wistar male rats divided into 4 groups : negative control (K-), positive control (K+), and two groups treated with Stichopus hermanii extract at doses of 486 mg/kg BB (KP1) and 972 mg/kg BB (KP2) for 23 days. The results of the study with Man-Whitney test showed that neither the groups treated with Stichopus hermanii extract at both doses of 486 mg/kg BB nor 972 mg/kg BB doses of Stichopus hermanii extract led to a significant reduction in ALT levels when compared to positive control. There was no significant difference in ALT levels between the two extract doses. The conclusion of this study is the administration of Stichopus hermanii extract at doses of 486 mg/kg BB dan 972 mg/kg BB for 23 days can not reduce ALT levels in aspirin-induced experimental animal.
Perbedaan Rasio Trombosit Limfosit Pre dan Post Terapi Kemoradiasi Kanker Serviks di Rumah Sakit Pusat Angkatan Laut dr. Ramelan Surabaya Marbentan, Purwo Diva Nadib; Sudiarta, Ketut Edy; Purwaningsari, Diah; Puspita, Angela
Jurnal Kedokteran Meditek Vol 31 No 1 (2025): JANUARI
Publisher : Fakultas Kedokteran Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jkdoktmeditek.v31i1.3105

Abstract

Introduction: Cervical cancer is caused by persistent infection with HPV transmitted through sexual intercourse. Chemoradiation is often used in the treatment of cervical cancer because it can reduce recurrence and further cell growth and can increase survival. Increased Platelet Lymphocyte Ratio (RTL) can be used to track the progression of cervical cancer and the degree of differentiation of cancer cells. High RTL indicates a worse degree of cell differentiation and vice versa. Purpose: The aim of this study was to determine the difference in RTL in cervical cancer patients pre and post chemoradiation therapy. Methods: The research design is cross-sectional with total sampling. Data was taken from medical records of cervical cancer patients at the Department of Obstetrics and Gynaecology, RSPAL dr. Ramelan Surabaya in year 2000 - 2023. Results: The average RTL for cervical cancer patients before chemoradiation was 193.1293; and after chemoradiation 169.5459. The results of the Wilcoxon signed rank test showed a significant decrease (p < 0.001). This research proves that there is a significant difference in the Platelet Lymphocyte Ratio (RTL) of stage ≥ IIB cervical cancer patients pre- and post-chemoradiation therapy. Statistical tests show significant results. Conclusion: Chemoradiation has been proven to significantly reduce RTL, and it can be concluded that giving chemoradiation to cervical cancer stage IIIB and above provides good results.
Co-Authors Albertus Magnus Arya Abisatya Ardiana, Dian Dian Ardiana Dio Rafid Prakoso Eric Mayo Dagradi Ferguszon, Devina Hanalily Maharani Firda, Armadani Aisyah Indri Ngesti Rahayu Ismylatifa Devi Jhouharotul Faradisah Komalasari, Intan Lestari Dewi Liliawanti Marbentan, Purwo Diva Nadib MILLENIAWATI PUTRI NOVITANIA Nita Pranitasari NITA PRANITASARI Poerwanto, Eka Prawesty Diah Utami Puspita, Angela PUTU SITHA AISHWARYA SARASWATI GIUR Giur RASYAD, CHICO MUHAMMAD Redemptus Yudadi RIFKY YOGA PRATAMA RIKE ANDY WIJAYA SAMSUDIN, MOH SAPTA PRIHARTONO RACHMAN Setianingsih, Herin Sihning E. J. T Sihning E.J.Tehupuring Sihning EJ Tehupuring Sudiarta, Ketut Edy Suhailah Hayaza Wachjudi Kurnia Wahyu Prasasti Mutiadesi Wienta Diarsvitri, Wienta Wijayanti, Ni Luh Putu Ratih