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The Effect Of Dawood's Fasting In Removing Total Blood Cholesterol Levels In Surabaya Hidayatullah Islamic Boarding School’s Student Rahayu, Indri Ngesti; Wijayanti, Ni Luh Putu Ratih; Purwaningsari, Diah; Komalasari, Intan; Dagradi, Eric Mayo
Jurnal Medis Islam Internasional Vol 3 No 1 (2021): December
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/iimj.v3i1.2445

Abstract

Background: Hypercholesterolemia is a risk factor for causing death at a young age. The World Health Organization reported in 2002 that 4.4 million deaths were caused by hypercholesterolemia, or 7.9% of the total number of deaths at a young age. Hypercholesterolemia is a condition in which cholesterol levels in the body exceed normal levels. One way that can be done to prevent hypercholesterolemia is to control diet, namely by fasting. Dawood’s fasting is one of the obligatory fasts of Islamwhich is done with one-day fasting and one-day not. Objective: This study aims to determine the effect of Dawood’s fasting in reducing total blood cholesterol levels in Hidayatullah Islamic Boarding School students in Surabaya.Methods: This study was designed with a quasi-experimental study research method using a comparative pre-test post-test non-equivalent control group design. The sample in this study was divided into two groups, namely one control group and one treatment group from the sample selected by purposive sampling. The population studied were students of the Hidayatullah Islamic Boarding School in Surabaya. Result: The results of statistical analysis using the Wilcoxon signed-rank test showed an effect of Dawood’s fasting in reducing total blood cholesterol levels in Hidayatullah Islamic Boarding School students in Surabaya.Conclusion: From research result that has been done, it can be concluded that there is an effect of Dawood’s fasting in reducing total blood cholesterol levels in Hidayatullah Islamic Boarding School students in Surabaya. Keywords: Dawood’s fasting, total blood cholesterol.
THE EFFECT OF ETHANOL EXTRACT OF Rhizophora mucronate LEAVES ON THE GROWTH OF Staphylococcus aureus BACTERIA Firda, Armadani Aisyah; Ardiana, Dian; Purwaningsari, Diah
Medical and Health Journal Vol 4 No 2 (2025): February
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.mhj.2025.4.2.14688

Abstract

Sebagian besar infeksi kulit di Indonesia disebabkan oleh bakteri Staphylococcus aureus yang bersifat patogen oportunistik dan bertanggung jawab atas permasalahan resistensi antibiotik Metisilin dan Vankomisin terhadap S.aureus. Daun bakau R. mucronata mengandung aktivitas antibakteri pada senyawa metabolit sekunder yakni fenol, flavonoid, saponin, tanin, dan terpenoid. Penelitian ini bertujuan untuk mengetahui pengaruh ekstrak etanol 96% daun bakau R. mucronata terhadap pertumbuhan bakteri Staphylococcus aureus. Penelitian dilakukan secara eksperimental laboratoris dengan sampel biakan murni Staphylococcus aureus murni, diambil dengan teknik random sampling, dicampur dengan aquades dan kekeruhannya setara dengan standarisasi 0,5 Mc Farland, ditanam di agar Mueller Hinton. Daun Bakau R. mucronata diekstraksi dengan metode maserasi dan dibuat 4 seri konsentrasi (25%, 50%, 75%, dan 100%). Uji antibakteri menggunakan metode difusi cakram dengan kontrol positif Siprofloksasin 5 mcg dan kontrol negatif akuades steril. Semua cawan petri dimasukkan kedalam inkubator selama 24 jam pada suhu 37°C, lalu diukur diameternya. Data dianalisis secara statistik dengan uji Nonparametrik Kruskal Wallis dan dilanjutkan uji posthoc Mann Whitney-U. Hasil penelitian menunjukkan peningkatan diameter zona hambat setiap konsentrasi ekstrak dengan aktivitas penghambatan tertinggi pada konsentrasi 100% sebesar 11,7 mm. Simpulan dalam penelitisn ini bahwa ekstrak etanol 96% daun bakau R. mucronata dapat menghambat pertumbuhan bakteri S.aureus secara in vitro
Perbedaan Rasio Trombosit Limfosit Pre dan Post Terapi Kemoradiasi Kanker Serviks di Rumah Sakit Pusat Angkatan Laut dr. Ramelan Surabaya Marbentan, Purwo Diva Nadib; Sudiarta, Ketut Edy; Purwaningsari, Diah; Puspita, Angela
Jurnal Kedokteran Meditek Vol 31 No 1 (2025): JANUARI
Publisher : Fakultas Kedokteran Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jkdoktmeditek.v31i1.3105

Abstract

Introduction: Cervical cancer is caused by persistent infection with HPV transmitted through sexual intercourse. Chemoradiation is often used in the treatment of cervical cancer because it can reduce recurrence and further cell growth and can increase survival. Increased Platelet Lymphocyte Ratio (RTL) can be used to track the progression of cervical cancer and the degree of differentiation of cancer cells. High RTL indicates a worse degree of cell differentiation and vice versa. Purpose: The aim of this study was to determine the difference in RTL in cervical cancer patients pre and post chemoradiation therapy. Methods: The research design is cross-sectional with total sampling. Data was taken from medical records of cervical cancer patients at the Department of Obstetrics and Gynaecology, RSPAL dr. Ramelan Surabaya in year 2000 - 2023. Results: The average RTL for cervical cancer patients before chemoradiation was 193.1293; and after chemoradiation 169.5459. The results of the Wilcoxon signed rank test showed a significant decrease (p < 0.001). This research proves that there is a significant difference in the Platelet Lymphocyte Ratio (RTL) of stage ≥ IIB cervical cancer patients pre- and post-chemoradiation therapy. Statistical tests show significant results. Conclusion: Chemoradiation has been proven to significantly reduce RTL, and it can be concluded that giving chemoradiation to cervical cancer stage IIIB and above provides good results.
Gambaran Sindrom Mata Kering pada Mahasiswa Fakultas Kedokteran Universitas Hang Tuah Angkatan 2018: Sindrom mata kering RASYAD, CHICO MUHAMMAD; SAMSUDIN, MOH; PURWANINGSARI, DIAH
Hang Tuah Medical Journal Vol 21 No 1 (2023): Hang Tuah Medical Journal
Publisher : Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/htmj.v21i1.161

Abstract

Dry eye syndrome (DES) is a multifactorial disease of the ocular surface caused by hyperosmolarity of tears. Dry eyes can interfere with activities because it causes pain dan discomfort in the eyes. Gender and duration of gadget use are part of the risk factor for dry eye syndrome. This study was conducted with the aim of knowing the description of dry eye syndrome in students of the Faculty of Medicine Hang Tuah University Class of 2018. This type of study is descriptive. This research was conducted at the Faculty of Medicine, Hang Tuah University. The study was conducted from April 2021-November 2021. Data were obtained from online questionnaires on 154 students of the Faculty of Medicine, Hang Tuah University, Class of 2018. The sample was selected using simple random sampling method. The result showed that the severity of dry eye syndrome was 20.1% in the normal category, 19.5% in the mild category 22.1% in the moderate category and 38.3% in the severe category. In the male gender, 32.6% were found normal, 20.9% in the mild category, 16.3% in the moderate category and 30.2% in the sever category. In female gender, 15.3% were found in the normal category, 19.0% in the mild category, 24.3% in the moderate DES and 41.4% in the severe DES. The light duration of gadget usage shows 66.7% mild and 33.3% in the severe DES. The medium duration of gadget usage shows 30.7% normal, 15.4% in the mild DES, 38.5% in the moderate DES, 15.4 in the severe DES. The severe duration of gadget usage shows 19.6% normal, 18.8% with mild DES, 21,0% with moderate DES and 40,6% with severe DES. The conclusion of this study is the severity of DES is high, the female gender has higher prevalence of severity compared to male gender and the severe duration of gadget usage has a higher prevalence of severity. Keyword: Dry eye syndrome, severity, gender, duration of gadget usage