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ANTIBAKTERI HUMAN BETA DEFENSIN-3 DALAM TERAPI PERIODONTITIS ika Andriani
B-Dent: Jurnal Kedokteran Gigi Universitas Baiturrahmah Volume 7, Nomor 2, Desember 2020
Publisher : Universitas Baiturrahmah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33854/jbd.v7i2.478

Abstract

Pendahuluan: Resistensi antimikroba konvensional pada bakteri patogen merupakan masalah kesehatan dan ekonomi masyarakat, maka perlu adanya alternative antimikroba dalam menangani infeksi. Antimikroba peptide kationik Human beta defensin-3 (HBD-3) yang dihasilkan epitel gingiva,secara alamiah ditemukan di dalam sistem imun tubuh manusia yang  merupakan antibakteri spektrum luas dan jarang menimbulkan resistensi bakteri serta alergi. Aktivitas antibakteri HBD-3 berpotensi sebagai bakteriosid periodontopathogen. Tujuan dari penulisan studi pustaka ini menggali potensi antibakteri peptide Human beta defensin-3 (HBD-3) sebagai alternative antibakteri untuk perawatan periodontitis. Tinjauan: Periodontitis merupakan peradangan jaringan periodontal disebabkan bakteri polimikrobial, menyebabkan kerusakan  jaringan pendukung gigi. Keterlibatan bakteri penyebab kerusakan jaringan periodontal pada periodontitis, sehingga perawatan periodontitis memerlukan antiobiotik. Penggunaan antibiotic yang tidak teratur menyebabkan resistensi bakteri, sehingga diperlukan antibakteri yang jarang menimbulkan resistensi. Hasil penelitian sebelumnya human beta defensin merupakan antibakteri yang jarang menimbulkan resitensi   Pembahasan: Human beta defensin-3 (HBD-3) merupakan antibakteri peptid yang menghambat bakteri secara luas baik bakteri gram positif maupun gram negative. Beberapa macam mekanisme HBD-3 dalam membunuh bakteri antara lain memodulasi respon imun dan membunuh sel target spesifik tanpa mempengaruhi sel inang sehingga jarang menimbulkan resistensi obat. Selain sebagai antibakteri, HBD-3 berperan sebagai innate immune dan adaptive immune, immunomodulator, penyembuhan luka, regenerasi epitel gingiva dan periodontal,   remodeling tulang alveolar serta memicu perbaikan tulang pada pasien dengan periodontitis, sehingga tidaklah berlebihan apabila HBD-3 merupakan alternative utama antibakteri dalam perawatan periodontitis. Simpulan: Human beta defensin-3 (HBD-3) berpotensi diterapkan dalam pengobatan  periodontitis.
Peningkatan Kesehatan Gigi dan Mulut Peserta Didik Madrasah Tsanawiyah Mu’allimat di Era Pandemi Covid-19 Ika Andriani; Hartanti Hartanti
Prosiding Seminar Nasional Program Pengabdian Masyarakat 2022: 3. Kesehatan Keluarga dan Masyarakat
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Madrasah Mu'allimat Muhammadiyah Yogyakarta merupakan sekolah dengan konsep sekolah asrama, siswa kelas 1 Tsanawiyah merupakan usia masih muda dan jauh dari orang tuanya perlu untuk diingatkan dan ditingkatan pengetahuan tentang kesehatan gigi dan mulutnya sehingga lebih mandiri dalam menjaga dan merawat kesehatan gigi dan mulut serta kesehatan dirinya di masa Pandemi Covid-19. Tujuan dari pengabdian masyarakat ini adalah meningkatkan pengetahuan kesehatan gigi dan mulut pada peserta didik dengan kegiatan edukasi atau penyuluhan kesehatan gigi dan mulut, cara mencegah dan penyebaran Covid-19 serta praktik cara menyikat gigi yang benar. Metode pengabdian dilakukan dengan edukasi penyuluhan kesehatan gigi dan mulut pada siswa kelas 1. Edukasi tentang protokol Kesehatan di masa Pandemi Covid-19, dan pelatihan sikat gigi pada siswa. Hasil yang didapatkan adalah terjadinya peningkatan pengetahuan anak tentang kebersihan gigi dan mulut
Hubungan Tingkat Kepedulian Orang Tua terhadap Status Oral Hygiene Anak Berkebutuhan Khusus Citra Lestari; Valendriyani Ningrum; Ika Andriani; Dwi Windu
e-GiGi Vol. 11 No. 1 (2023): e-GiGi
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/eg.v11i1.44202

Abstract

Abstract: Oral health problems among special needs children (SNC) is a priority and concern of all parties, both parents/caregivers, dentists and health policy makers both nationally and regionally as soon as possible. This study aimed to determine the relationship between the level of parental care and the oral hygiene of children at SLB Wacana Asih, Padang. This was an analytical and survey study with a cross-sectional design. Sampling was performed by using total sampling, consisting of parents of SNC and the SNC as many as 82 children. Data were analyzed using the Spearman Rank test with a significance level of p<0.05. The results showed that parent’s attention to the dental and oral hygiene of SNC was 53.66% in the good category and 46.445% in the moderate category. Furthermore, the results of the examination of the oral hygiene status of SNC showed various levels of status, as follows: good (45.1%), moderate (28%), and poor (26.8%). The statistical correlation test obtained a p-value of 0.000 which indicated that there was a significant relationship between parental care and the oral hygiene status of SNC with a correlation coefficient of r 0.699, which means a strong positive relationship. In conclusion, the higher the concern of parents, the better the oral hygiene status of special needs children. Keywords: parental care; oral hygiene; special needs children   Abstrak: Masalah kebersihan gigi dan mulut pada anak berkebutuhan khusus (ABK) merupakan prioritas yang perlu mendapat perhatian semua pihak yaitu orang tua, pengasuh, dokter gigi dan pengampu kebijakan kesehatan baik nasional maupun daerah sedini mungkin. Penelitian ini bertu-juan untuk mengetahui hubungan antara tingkat kepedulian orang tua dengan oral hygiene anak SLB Wacana Asih, Kota Padang. Jenis penelitian ialah survei analitik dengan desain potong lintang. Metode pengambilan sampel ialah total sampling yaitu orang tua dari ABK dan ABK sebanyak 82 anak. Data penelitian diuji menggunakan uji Spearman Rank dengan tingkat signifikansi p<0,05. Hasil penelitian menunjukkan bahwa kepedulian orang tua tentang kebersihan gigi dan mulut ABK dengan kategori baik sebanyak 53,66%, sedangkan kategori cukup baik sebesar 46,445%. Hasil pemeriksaan status oral hygiene ABK menunjukkan berbagai level status yakni: baik (45,1%), sedang (28%) dan buruk (26,8%). Hasil uji korelasi mendapatkan p=0,000 yang menunjukkan hubungan bermakna anatara kepedulian orang tua dengan status oral hygiene ABK dengan nilai koefisien korelasi r 0.699 yang bermakna hubungan positif kuat. Simpulan penelitian ini ialah sema-kin tinggi kepedulian orang tua maka akan semakin baik status oral hygiene berkebutuhan khusus. Kata kunci: kepedulian orang tua; oral hygiene; anak berkebutuhan khusus  
The Activity of Active Compounds of Papaya Leaf (Carica Papaya L.) in Inhibiting the Growth of Fungus Candida Albicans in the Oral Cavity Ana Medawati; Ika Andriani; Atiek Driana Rahmawati; Nanik Hidayati
Formosa Journal of Sustainable Research Vol. 2 No. 7 (2023): July 2023
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/fjsr.v2i7.5306

Abstract

Candida albicans is the most frequently isolated candida species from the oral cavity. The overgrowth of C. albicans can cause opportunistic infections in the oral cavity, called oral candidiasis. On the other hand, papaya leaves (Carica papaya L.) have benefits and are efficacious as antifungal drugs. The results of various studies reveal that papaya leaves (Carica papaya L.) contain various active compounds, such as flavonoids, alkaloids, saponins, and tannins, which can inhibit the growth of C. albicans fungus. This literature review, therefore, aims to ascertain the activity of active compounds in papaya leaves in inhibiting the growth of C. albicans in the oral cavity
Pengaruh Metode Inquiry Terbimbing terhadap Prestasi Belajar dan Keterampilan Berpikir Kritis Peserta Didik SMA Negeri 16 Makassar Andriani, Ika
Gravity Edu : Jurnal Pembelajaran dan Pengajaran Fisika Vol 6 No 1 (2023): Gravity Edu : Jurnal Pembelajaran dan Pengajaran Fisika
Publisher : Sekolah Tinggi Keguruan dan Ilmu Pendidikan Bima

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33627/ge.v6i1.1093

Abstract

Penelitian ini merupakan penelitian true eksperimental dengan desain the randomized postest-only control group design. Populasi pada penelitian ini adalah seluruh peserta didik kelas XI MIA semester genap di SMA Negeri 16 Makassar. Penentuan sampel dengan simple random sampling. Instrumen pengukuran divalidasi oleh ahli, dilanjutkan dengan uji coba peserta didik. Hasil penelitian ini menunjukkan bahwa terdapat: (i) perbedaan prestasi belajar yang signifikan antara yang diajar dengan menerapkan metode inquiry terbimbing dan yang diajar dengan menerapkan metode inquiry bebas termodifikasi. (ii) perbedaan keterampilan berpikir kritis yang signifikan antara yang diajar dengan menerapkan metode inquiry terbimbing dan yang diajar dengan menerapkan metode inquiry bebas termodifikasi pada peserta didik kelas XI MIA SMA Negeri 16 Makassar
The effect of the pseudostem extract of ambon banana on the number of lymphocytes and fibroblasts in gingivitis : an experimental study andriani, Ika; Medawati, Ana; Lestra, Citra; Salsabila, Millati; Khairunnisa, Putri Nabilla
Padjadjaran Journal of Dentistry Vol 35, No 3 (2023): November 2023
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/pjd.vol35no3.49051

Abstract

ABSTRACTIntroduction: Gingivitis is an inflammation of the soft tissue that supports the teeth. Chemical treatment in the form of mouthwash, such as chlorhexidine, is often recommended. However, long-term use of chlorhexidine mouthwash will cause side effects, such as allergies, irritation of the oral cavity, and discoloration of the oral mucosa and teeth. Therefore, natural alternative materials containing flavonoids, saponins, and tannins that can cure gingivitis are needed. These ingredients are found in the pseudo stem of the Ambon banana. This research aims to analyze the effect of applying the pseudostem extract of Ambon banana on the number of lymphocytes and fibroblasts in treating gingivitis. Methods: This study was an in vivo laboratory experimental study with a post-test control group. The study used 45 Sprague Dawley rats which were divided into 3 groups, namely the positive control group (chlorhexidine gel), negative control (gel base), and treatment (Ambon Banana pseudostem extract gel). The gingiva on the mandibular incisor of the rat was ligated, then the gel was applied to the gingiva. Decapitation of rats was carried out on days 1, 3, 5, 7, and 9, and then made histological preparations with HE. Staining and observations were later made. Data analyzed using Kruskal-Wallis test. Results: The results showed that Ambon banana false stem extract gel reduced the number of lymphocyte cells with a significant difference of p=0.016 (p<0.05) and increased fibroblasts at p=0.85 (p>0.05). Conclusion: The pseudostem extract gel of Ambon banana reduced the number of lymphocyte cells and increased fibroblasts in gingivitis treatment.Keywords: fibroblasts, gingivitis, lymphocytes, pseudostem of ambon banana
PENYULUHAN KEBERSIHAN GIGI ANAK DI PEDUKUHAN KORIPAN Nyka Dwi Febria; Dian Yosi Arinawati; Ika Andriani; Wustha Farani; Nabila Hasna Fitria
Jurnal Hasil Pengabdian kepada Masyarakat Universitas Jember Vol 1 No 2 (2022): Jurnal Hasil Pengabdian Kepada Masyarakat Universitas Jember
Publisher : LP2M Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/jpmunej.v1i2.137

Abstract

Poncosari is a subdistrict which has 24 hamlets. Koripan is one of the hamlets in Poncosari. Koripan became a place for community service activities by KKN (Kuliah Kerja Nyata) students of group 109 Muhammadiyah University of Yogyakarta in 2022. Community service aims to increase public knowledge about dental and oral health of TPA (Taman Pendidikan Al-Quran) children in Koripan hamlet . The service method is carried out by providing dental and oral health counseling to children. This activity was carried out with the community and youth organizations as TPA mentors. The results obtained are an increase in children's knowledge about dental and oral hygiene. The conclusion from the community service carried out can increase children's knowledge about health.
The Association of Stress with the Occurrence of Recurrent Aphthous Stomatitis (RAS) Amid the COVID-19 Pandemic in Students of Senior High School Medawati, Ana; Andriani, Ika; Driana Rahmawati, Atiek; Femilian, Afryla; Nur Arifta, Arum; Adi Saputra, Septian
Jurnal Kesehatan Gigi Vol 11, No 2 (2024): Desember 2024
Publisher : Jurusan Kesehatan Gigi, Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jkg.v11i2.12148

Abstract

The most prevalent oral mucosal lesion is Recurrent Aphthous Stomatitis (RAS). SAR can occur due to local trauma, stress, drug use, hormonal changes, nutritional deficiencies, immunological factors, smoking, hereditary and genetic factors, microbial factors, food hypersensitivity, hematinic deficiencies, and human immunodeficiency (HIV) infection. RAS is a prevalent condition that is defined by the presence of round ulcers that appear as recurrent lesions, numerous, small, round, have a yellowish base, and are surrounded by an erythematous halo and can occur in young and adult ages. Specifically, the pandemic caused by COVID-19 has affected people's lives around the world, including senior high school students. The incidence of RAS in adolescents is categorized as high; according to the findings of RISKESDAS, the percentage is 8.7%. Stress is a contributing component to the development of RAS. The objective of this investigation was to ascertain the correlation between stress and the prevalence of RAS during the COVID19 pandemic. This investigation employed a cross-sectional design and was observational analytic. A total of 104 research subjects were included in the study, which was conducted on students at SMA Negeri 6 in Yogyakarta. The results revealed 59 respondents with normal stress levels, of which 57 respondents (54.8%) were positive for RAS. The Spearman Rank correlation statistical test was employed to analyze the data, resulting in a significant value of p = 0.019 or 0.05, which denotes a correlation stress and the occurrence of RAS during the COVID-19 pandemic in students at SMA 6 Yogyakarta, serving as the conclusion
DAYA HAMBAT PROBIOTIK DALAM MINUMAN YOGHURT SQUEEZE PLAIN TERHADAP PERTUMBUHAN BAKTERI FUSOBACTERIUM NUCLEATUM Andriani, Ika; Fitria, Salza Sa’datul Putri
B-Dent: Jurnal Kedokteran Gigi Universitas Baiturrahmah Vol 11, No 2 (2024): Vol. 11,No 2 (Desember 2024)
Publisher : Universitas Baiturrahmah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33854/jbd.v11i2.1703

Abstract

Introduction: Periodontal disease is an inflammatory condition that affects the supporting tissues of teeth due to the accumulation of plaque bacteria. Various efforts have been made to control plaque in periodontal disease, one of which is the use of processed products containing probiotics, namely yoghurt. Aim: This study aims to determine the potential probiotic content in one of commercially available plain yoghurt to inhibit the growth of Fusobacterium nucleatum bacteria. Methods: This was a laboratory experimental study employing a disc diffusion method with a post-test-only control group design, comprising three groups with nine replicates each. A bacterial suspension of Fusobacterium nucleatum, standardized to a 0.5 McFarland turbidity, was inoculated onto Mueller-Hinton agar (MHA) plates. Paper discs impregnated with commercially available plain yogurt (treatment group), chlorhexidine (positive control group), and sterile distilled water (negative control group) were then placed on the inoculated MHA. Result: The mean inhibition zone diameter against Fusobacterium nucleatum in the treatment group was 10.8 mm.The Kruskal-Wallis test revealed a statistically significant difference in inhibition zone diameters among the groups (p < 0.001). Conclusion: These findings suggest that the commercially available plain yogurt may possess the potential to inhibit the growth of Fusobacterium nucleatum
Relationship between sleep patterns, bedtime and recurrent aphthous stomatitis (RAS) during the COVID-19 pandemic: analytical observational research Saputro, Septian Adi; Arifta, Arum Nur; Medawati, Ana; Andriani, Ika; Rahmawati, Atiek Driana; Femilian, Afryla; Perdana, Lutfi Putra
Padjadjaran Journal of Dentistry Vol 36, No 3 (2024): November 2024
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/pjd.vol36no3.56929

Abstract

Introduction: Recurrent Aphthous Stomatitis (RAS) is an inflammation on the oral mucosa, presenting as recurrent, round, single, or multiple ulcers with well-defined boundaries. Although the exact etiology of RAS remains unknown, several factors are known to contribute to its development. During the COVID-19 pandemic, various problems have arisen, especially among adolescents, including senior high school students, whose sleep patterns-specifically their sleep time, duration, and quality-have been disrupted. These disruptions may weaken their immune system, making them more susceptible to RAS disease. The objective of this study is to analyze the relationship between sleep patterns, bedtime, and the occurrence of RAS during the COVID-19 pandemic. Method: The research design employed was an analytical observational study, with a cross-sectional approach. Purposive sampling was used to select all class XI students of SMA  6 Yogyakarta, based on inclusion and exclusion criteria. The research instruments included the PSQI questionnaire (used to measure sleep patterns, sleep time, sleep duration, and sleep quality) and the RASDX questionnaire (a diagnostic tool for measuring the prevalence of RAS lesions) both administered via Google Forms. Statistical analysis was conducted using the Chi-square test. Results: A total of 58 students (55.8%) experienced RAS, with a higher prevalence among female students. Regarding age, 16-year-old students had the highest incidence of RAS, with 79 students (64.4%) affected. Most respondents, 79 respondents (76%), were reported to have good sleep patterns. The results of the bivariate analysis also revealed a significant relationship between sleep patterns, bedtime, and the occurrence of RAS (p=0.043<0.05). Conclusion: Sleep patterns, bedtime, and the occurrence of RAS were found to be interrelated during the COVID-19 pandemic.