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All Journal PHARMACON Pharmascience Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) Martabe : Jurnal Pengabdian Kepada Masyarakat Jurnal Review Pendidikan dan Pengajaran (JRPP) Hydrogen: Jurnal Kependidikan Kimia Room of Civil Society Development Jurnal Ilmiah Kebidanan dan Kesehatan (JIBI) Karya Kesehatan Journal of Community Engagement Jurnal Ilmiah Kesehatan Sandi Husada MPSJ
Hasnaeni hasnaeni, Hasnaeni
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Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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A Literature Review: Antimicrobial Phenolic Compounds in Nutmeg (Myristica fragrans Houtt) Ipaenin, Jahiria; Chabib, Lutfi; Hasnaeni, Hasnaeni; Tunny, Risman
Hydrogen: Jurnal Kependidikan Kimia Vol 13, No 1 (2025): February 2025
Publisher : Universitas Pendidikan Mandalika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33394/hjkk.v13i1.14583

Abstract

In various countries, testing of phenolic compounds in plants is always carried out because these compounds have various health benefits such as antioxidant, anti-inflammatory, and antimicrobial activities. The types of medicinal plants in Indonesia are known to be very diverse where those included in the medicinal plant group reach more than 1000 species, one of which is nutmeg (Myristica fragrans Houtt.) Nutmeg (Myristica fragrans Houtt.) itself is native to the Maluku Islands, Indonesia. However, besides the Moluccas, nutmeg is also cultivated in several other tropical countries. The main objective of this literature review is to critically examine the antimicrobial properties and identify the specific antimicrobial components of phenolic compounds contained in nutmeg (Myristica fragrans Houtt.) The methodology used in this study involved a comprehensive literature review by utilizing reputable academic databases such as Google Scholar, PubMed, and Science Direct related to articles published between 2019 and 2024. The results of this study were obtained through a thorough search process, resulting in eight articles that were considered to meet the established inclusion criteria. A number of articles showed the effectiveness of nutmeg as an antimicrobial because nutmeg contains phenolic compounds that have antibacterial and antifungal properties, which make it effective as an antimicrobial agent. Therefore, with a more comprehensive understanding of the content of phenolic compounds and their mechanism of action, nutmeg can be a further basis for study in the health sector and the pharmaceutical industry.
Pemisahan Senyawa Flavonoid pada Tanaman Keji Beling (Strobhilantes crispa) Hasnaeni, Hasnaeni; Ananda, Andi Melvi Riski; Amriati, Rezki
Jurnal Pharmascience Vol 12, No 1 (2025): Jurnal Pharmascience
Publisher : Program Studi Farmasi FMIPA Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v12i1.16886

Abstract

Tanaman Keji Beling (Strobhilantes crispa) termasuk famili Acanthaceae yang dapat digunakan sebagai antidiabetes, diuretik, ansispilis, antioksidan dan antimikroba.Tujuan penelitian ini untuk memisahkan senyawa teridentifikasi  sebagai flavonoid pada ekstrak daun keji beling (S. crispa) dengan menggunakan metode kromatografi kolom. Daun keji beling (S. crispa) diekstraksi dengan metode maserasi menggunakan pelarut etanol96%. Identifikasi senyawa flavonoid dilakukan dengan kromatografi lapis tipis. Fase gerak yang digunakan adalah : Etil asetat : n-Heksan (8:2). Hasil KLT diperoleh bercak pemisahan dengan Rf 0,80.  Identifikasi hasil pemisahan menggunakan preaksi spesifik seperti H2SO4, FeCl3, HCl dan menunjukkan hasil positif  flavonoid.
Yoga Hamil terhadap Penurunan Nyeri Punggung pada Ibu Hamil Trimester III: Pregnancy Yoga In Reducing Back Pain In Pregnant Women In The Third Trimester Ni Made Diah Intari; Izzah, Alifia Nurul; Fabumase, Ana; Enumbi, Yomince; Hasnaeni, Hasnaeni
Jurnal Ilmiah Kebidanan dan Kesehatan (JIBI) Vol. 3 No. 1 (2025): Volume 3 Nomor 1 Mei 2025
Publisher : Sarana Ilmu Indonesia (salnesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36590/jibi.v3i1.1341

Abstract

Nyeri punggung merupakan salah satu keluhan fisik yang sering dialami oleh ibu hamil, terutama pada trimester ketiga. Nyeri punggung bawah sering dialami oleh ibu hamil akibat beratnya beban janin dan perubahan posisi janin didalam rahim menyebabkan ibu hamil mengalami gangguan otot dan sendi. Nyeri punggung dapat menurunkan kualitas hidup ibu hamil dan merugikan pertumbuhan janin. Oleh karena itu diperlukan suatu penanggulangan untuk mengatasi keluhan tersebut sehingga ibu dan janin mendapatkan manfaat dan dapat tumbuh kembang dengan baik. Salah satu penanggulangan nyeri punggung yang sering dilakukan adalah kegiatan senam hamil dan yoga hamil. Senam hamil dan yoga hamil merupakan upaya relaksasi otot dan sendi serta memperlancar sirkulasi darah, sehingga diharapkan dapat mengurangi beban pada otot dan sendi dan mengurangi nyeri punggung. Penelitian ini bertujuan untuk meninjau bukti-bukti dari hasil penelitian sebelumnya mengenai pengaruh senam dan yoga hamil terhadap penurunan keluhan nyeri punggung yang umumnya dialami ibu hamil trisemester III. Dengan menelaah berbagai metode dan hasil dari penelitian terdahulu. Metode yang digunakan pada literature review ini adalah penelusuran jurnal dan artikel ilmiah yang relevan. Kata kunci yang digunakan dalam pencarian adalah "efektivitas senam dan yoga hamil terhadap penurunan nyeri punggung pada ibu hamil trisemester III". Sumber yang digunakan adalah (Google Scholar dan Microsoft edge). Artikel yang ditemukan kemudian dilakukan seleksi berdasarkan tingkat relevansinya dengan topik penelitian. Metode yang dijelaskan pada masing-masing artikel kemudian dirangkum dan dianalisis untuk menjawab masalah penelitian. Hasil review literatur ini akan digunakan sebagai dasar dalam merancang penelitian empiris selanjutnya. Berdasarkan penelusuran literatur, didapatkan 60 artikel yang sesuai dengan kriteria. Ke-60 artikel tersebut melakukan penelitian dengan subjek ibu hamil trimester III dan memberikan intervensi berupa senam atau yoga hamil. Hasil penelitian secara umum menunjukkan bahwa senam maupun yoga hamil efektif dalam menurunkan nyeri punggung pada ibu hamil trimester III. Penurunan nyeri punggung tersebut secara statistik signifikan. Dengan demikian, yoga hamil efektif untuk menanggulangi keluhan nyeri punggung umumnya pada ibu hamil trisemester III.
The effectiveness of giving young coconut water in reducing dysmenorrhea symptoms: A case study of midwifery care Dahniar, Dahniar; Fauziah, Putri; Marbun, Uliarta; Hasnaeni, Hasnaeni
Jurnal Ilmiah Kesehatan Sandi Husada Vol 13 No 2 (2024): Jurnal Ilmiah Kesehatan Sandi Husada
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Akademi Keperawatan Sandi Karsa (Merger) Politeknik Sandi Karsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35816/jiskh.v13i2.1220

Abstract

Introduction: Dysmenorrhea is a common condition in women during menstruation, characterized by severe pain that can interfere with daily activities. The administration of medical therapy is often used to treat these symptoms, but natural approaches such as giving young coconut water are also starting to be considered. Objective: This study aims to analyze the effectiveness of giving young coconut water in reducing pain intensity in dysmenorrhea patients and provide an overview of the application of natural therapy-based obstetric care in patients with menstrual complaints. Methods: This study uses a case study design with a qualitative approach. The subject of the study was an adult woman who experienced primary dysmenorrhea. Data were collected through in-depth interviews, direct observation, and assessment of pain intensity using the VAS (Visual Analog Scale) scale before and after administering young coconut water. Result: The study showed a significant decrease in the intensity of dysmenorrhea pain after administering young coconut water. Before the administration of therapy, patients reported pain intensity at level 8 (scale 0-10), and after three days of administration of young coconut water, pain intensity decreased to level 3. Patients also reported feeling more comfortable and being able to continue their daily activities better. No significant side effects were found related to the consumption of young coconut water. I am injuring kei three mestiuia such does not feel jealous, the nature of the blood of meirah can bioactivity deingan good to know the absence of the current suidah in the absence of good. Conclusion: Giving young coconut water can be effective in reducing the symptoms of dysmenorrhea in patients who experience it. This therapy can be a safe and natural alternative to help relieve menstrual pain. It can be applied in obstetrics as part of a comprehensive approach to reproductive health care. Further research with larger samples is needed to reinforce these findings and explore the mechanism of action of young coconut water in dysmenorrhea
Uji Aktivitas Antioksidan dan Profil Fitokimia Ekstrak Kayu Beta-beta (Lunasia amara Blanco.): Antioxidant Activity and Phytochemical Profile of Beta-beta (Lunasia amara Blanco) Wood Extract Hasnaeni, Hasnaeni; Aminah, Aminah
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 5 No. 1 (2019): (March 2019)
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (152.43 KB) | DOI: 10.22487/j24428744.2019.v5.i1.12404

Abstract

Beta-beta wood (Lunasia amara Blanco) is one of the Rutaceae plants. It has been used traditionally in Indonesia, both in the form of a single extract or in a mixture of several herbs, for the treatment of swollen feet, skin diseases and inflammation or irritation of the eyes. This study aims to examine the antioxidant activity and the phytochemical profile of beta-beta wood extract. The research methods include plant extraction by maceration, testing of antioxidant activity by 2,2-diphenyl-1-picrylhydrazyl (DPPH) method and phytochemical profiling with specific chemical reagents. The results showed that beta-beta wood extract (Lunasia amara Blanco) has antioxidant activity with IC50 was 69.46 μg/ml (0.069 mg/ml) and it contained steroid, phenolic, saponin, alkaloid and coumarin compounds.
Pengaruh Metode Ekstraksi Terhadap Rendemen Dan Kadar Fenolik Ekstrak Tanaman Kayu Beta-Beta (Lunasia amara Blanco): (The Effect of Extraction Method on Yield Value and Phenolic Content of Beta-Beta (Lunasia amara Blanco) Bark Extract Hasnaeni, Hasnaeni; usman, suriati; Wisdawati, Wisdawati
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 5 No. 2 (2019): (October 2019)
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (278.094 KB) | DOI: 10.22487/j24428744.2019.v5.i2.13599

Abstract

Lunasia amara Blanco bark belonging to the family Rutaceae. The research aimed to determine the effect of extraction method on yield value and phenolic content of bark extract of Lunasia amara Blanco by UV-Vis spectrophotometry. Sample was extracted by maceration, reflux, and soxhlet using methanol 70%. The extraction by maceration obtained the yield value of methanol extract of 2,352%; the reflux method of 1,611%; and the soxhlet method of 0,960%. Then the chemical content was identified by the addition of FeCl3 reagent and a blackish green color was formed positively indicating phenolic content. Afterward, phenolic identification was conducted by TLC with eluent n-hexane: ethyl acetate (2:8) containing phenolic because the Rf value was the same as the galic acid standard. The results showed that the extraction method producing the highest yield of bark extract of Lunasia amara Blanco was maceration. The phenolic content obtained by maceration was 66,548 mgGAE/g extract with 6.6548% GAE; the reflux was 73.645 mgGAE/g extract with 7.3645% GAE; and the soxhlet was 74.806 mgGAE/g extract with 7.4806% GAE.
OPTIMASI METODE EKSTRAKSI MASERASI DAN ULTRASOUND ASSISTED EXTRACTION (UAE) RIMPANG KUNYIT (CURCUMA LONGA L.) DAN AKTIVITAS ANTIOKSIDANNYA Tulnisa, Hijeria; Ahmad, Aktsar Roskiana; Hasnaeni, Hasnaeni
Jurnal Review Pendidikan dan Pengajaran Vol. 8 No. 2 (2025): Volume 8 No. 2 Tahun 2025
Publisher : LPPM Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jrpp.v8i2.44563

Abstract

Rimpang kunyit (Curcuma longa L.) adalah tumbuhan tropis yang banyak tumbuh di Benua Asia dan sering dimanfaatkan sebagai pewarna, pengharum makanan dan obat tradisional. Bagian yang paling banyak digunakan dari kunyit adalah rimpang. Kandungan rimpang kunyit terdiri senyawa alkaloid, flavonoid, tanin, kurkumin dan minyak atsiri. Kandungan kunyit digunakan sebagai obat tradisional yang berperan sebagai penambah nafsu makan, obat luka, gatal-gatal, antidiare, antibakteri, bahan kosmetik, dan antioksidan. Tujuan penelitian ini adalah Untuk mengetahui pengaruh suhu dan waktu ekstraksi pada ekstrak rimpang kunyit dengan menggunakan metode Ultrasound Assisted Extraction (UAE) terhadap aktivitas antioksidan dengan metode DPPH. Jenis penelitian yang digunakan adalah penelitian eksperimental laboratorium. Hasil penelitian menunjukkan bahwa persen kadar flavonoid ekstrak rimpang kunyit 2,755% dengan metode maserasi dan 2,913% dengan metode UAE. Sedangkan persen kadar fenolik ekstrak rimpang kunyit 3,142% dengan metode maserasi dan 2,854% dengan metode UAE. Aktivitas antioksidan ekstrak rimpang kunyit dengan ekstraksi metode maserasi dan UAE berturut-turut sebesar 14,467 μg/mL dan 19,349 μg/mL tergolong kuat karena nilai IC50 nya berada diantara 10 – 50 μg/mL. Hasil penelitian dapat disimpulkan bahwa Ekstraksi dengan metode maserasi menghasilkan kadar fenolik dan flavonoid total yang lebih tinggi dibandingkan dengan metode UAE pada rimpang kunyit.
STUDI ETNOFARMASI TUMBUHAN OBAT SEBAGAI ANTIHIPERTENSI DI DESA PATTALLASSANG, KECAMATAN PATTALLASSANG KABUPATEN GOWA Fadhilah, Putri Nur; Malik, Abd.; Hasnaeni, Hasnaeni
Makassar Pharmaceutical Science Journal (MPSJ) Vol 3 No 1 (2025)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v3i1.332

Abstract

Hypertension remains a prevalent global health concern and leading cause of mortality worldwide. In Pattallassang Village, traditional medicine utilizing medicinal plants persists as a common therapeutic approach for hypertension management. This study aimed to systematically identify, document and evaluate the ethnomedicinal knowledge of local communities regarding antihypertensive plants. Employing a descriptive observational design, data were collected through structured interviews and questionnaires administered to 100 respondents. The investigation identified 31 plant species utilized as antihypertensive agents, with the most prevalent being Allium sativum (garlic), Cucumis sativus (cucumber), Annona muricata (soursop leaves), Apium graveolens (celery), and Syzygium polyanthum (bay leaf). The leaves were boiled and the decoction was consumed as herbal infusions. Quantitative analysis using Use Value (UV) indices revealed Allium sativum as the most utilized species (UV=0.41), followed by Cucumis sativus (0.26), Apium graveolens (0.16), and Annona muricata (0.15). These findings demonstrate the preservation of significant ethnobotanical knowledge within the community regarding plant-based hypertension treatment. The study highlights the need for: (1) conservation efforts to protect this traditional knowledge, and (2) further pharmacological research to validate the therapeutic efficacy of these plants. Keywords: Ethnopharmaceutical; medicinal plants; Hypertension; Traditional Medicine; Pattallassang Village
Co-Authors A, Alfiah ABD. MALIK Afifah S, Nur Ahmad, Aktsar Roskiana Aminah Aminah Amriati, Rezki Ananda, Andi Melvi Riski Andi Emelda Andina, Velda Dahniar Dahniar Enumbi, Yomince Erna Kadrianti Fabumase, Ana Fadhilah, Putri Nur Fakruddin, Muh. Faranina, Nurul Arana Fauziah, Putri Firawati Firawati Indah Pratiwi Ipaenin, Jahiria Izzah, Alifia Nurul Kadir, Arisna Kasim, Jamila Lutfi Chabib, Lutfi Mirawati Mirawati Ni Made Diah Intari Nuraqidah, Nuraqidah Nurlinda Nurlinda, Nurlinda Purnama Sari, Lili Ramadani, Putri Pratiwi Risda Waris, Risda Saputri, Imel Selpida Handayani, Selpida Tulnisa, Hijeria Tunny, Risman Ulfa, Amanda Uliarta Marbun Usman Usman usman, suriati Wahyuddin Wahyuddin Wisdawati, Wisdawati Wusurwut, Fahriya