Article Per Year (5 Year)
p-Index From 2021 - 2026
0.444
P-Index
This Author published in this journals
All Journal JURNAL BIOLOGI INDONESIA ZOO INDONESIA Health and Medical Journal Proceeding Biology Education Conference Annales Bogorienses
Herjuno Ari Nugroho, Herjuno Ari
Unknown Affiliation
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Public Health Other

Published : 11 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 11 Documents
Search

 1   2 
Screening of Active Compounds and LC50 Toxicity Assay of Sunda Porcupine’s (Hystrix javanica F. Cuvier 1823) Quills Crude Extract Budiman, Muhamad Arif; Ferdian, Pamungkas Rizki; Handayani, Tri Hadi; Nugroho, Herjuno Ari; Elfirta, Rizki Rabeca; Farida, Wartika Rosa
Annales Bogorienses Vol. 25 No. 2 (2021): Annales Bogorienses
Publisher : BRIN

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Sunda porcupine (Hystrix javanica F. Cuvier 1823) is an endemic fauna from Indonesia that its quills are believed to have medical benefits by local people in some regions of Indonesia. However, the benefits have never been well recorded nor proven scientifically. Local people believe the Sunda porcupine’s quills have efficacy to relieve property for treating toothache. There is limited research on Sunda porcupine’s quills, especially the active compounds, which may affect toothache. This research aims to perform basic pharmacological experiments on Sunda porcupine’s quill samples, which includes screening for the active compounds and determining the LC50 toxicity using brine shrimp lethality test (BSLT) method. Sunda porcupine’s quills were first prepared into simplicia powder (60 mesh in size) and then extracted with 70% ethanol by maceration to produce crude extract. We found that the crude extract of Sunda porcupine’s quills contains some active compounds, including alkaloids, flavonoids, saponins, triterpenoids, steroids, and peptides. The LC50 value of the crude extract was 2,683.19 ppm; thus, categorized as non-toxic. These findings can be used to identify the active compounds in Sunda porcupine’s quills and can be used as a background for further research.
Co-Authors Agustiyanti, Dian Fitria Andri Permata Sari, Andri Permata ANDRIA AGUSTA Anita, Syahfitri Anky Zannati Azika, Wira Norman Budi Haryanto Budiman, Muhamad Arif DEWI WULANSARI Elfirta, Rizki Rabeca Erdayani, Eva Ferdian, Pamungkas Rizki Handayani, Tri Hadi Idris Idris Indriawati, Indriawati Moch. Syamsul Arifin Zein, Moch. Syamsul Arifin Nurul Inayah Popi Hadi Wisnuwardhani, Popi Hadi Putra, Andika Chandra RATIH ASMANA NINGRUM Ridwanuloh, Asep Muhammad Saniyyah, Zahrah Setiawan, Ruby Setyawan, Ryan Haryo Sinta Maharani Sofyani, Umar Sushadi, Pangda Sopha Utomo, Ahmad Rusdan Handoyo wahyuni wahyuni Wartika Rosa Farida Wulandari, Ari Sulistyo Zaini, Jamal