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Pengaruh Parameter Proses Electrospinning pada Komposit Polyvinylidene Fluoride/Polyacrylonitrile Nanofiber Sriyanti, Ida; Almafie, Muhammad Rama; Dani, Rahma; Idjan, Meutia Kamilatun Nuha Ap; Partan, Radiyati Umi; Sanjaya, M Rudi; Jauhari, Jaidan
Jurnal Penelitian Pendidikan IPA Vol 9 No 9 (2023): September
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v9i9.4840

Abstract

PAN cannot be used as a stand-alone nanofiber, so it needs to be modified through copolymerization with other polymers, such as PVDF. It is composite mutually beneficial for both PVDF/PAN polymers. Study aims to see the effect of process parameters, such as voltage, flow rate and needle tip distance of PVDF/PAN composite nanofiber as well as molecular interaction and crystal structure, to confirm the presence of polymer in the nanofiber composite. The nanofibers with solution parameters PN1: PVDF 6% and PAN 8%, PN2: PVDF 6% and PAN 10%, and PN3: PVDF 6% and PAN 12% were prepared using electrospinning. Morphology of the process parameters of voltage (12kV, 16kV, 18kV), flow rate (30 μl/min, 60 μl/min, 90 μl/min) and needle tip distance (75 mm, 100 mm, 125 mm) were observed. The results showed straight and continuous fibre morphology, with a smooth surface and no beaded structure, with homogeneous fibre distribution with an increase in diameter from 394 ± 79 nm (NF1) to 851 ± 89 nm (NF3). The optimal state was in the solution of PN2: PAN 10% (w/w) and PVDF 6% (w/w), High Voltage 12 kV, Flow Rate PN3: 60 μl/min, and Needle to Collector Distance 75 mm.
Osteoarthritis Medication and Overview: A Narrative Review Partan, Radiyati Umi
Open Access Indonesian Journal of Medical Reviews Vol. 2 No. 1 (2022): Open Access Indonesian Journal of Medical Reviews
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/oaijmr.v2i1.153

Abstract

Osteoarthritis, the most common form of joint disease, is primarily a disease of aging. Ninety percent of all people have radiographic features of osteoarthritis in weight-bearing joints by age 40. Symptomatic disease increases with age. Risk factors for this disorder include gender, genetics, obesity, and work history. Osteoarthritis develops in women more often than in men. This arthropathy is characterized by cartilage degeneration and bony hypertrophy at the articular margins. Inflammation is usually minimal. Hereditary and mechanical factors may be involved in the pathogenesis. This review provides an overview of counseling osteoarthritis and its treatment and management.
Vitamin D Levels in Epilepsy Patients at the Neurology Polyclinic, Dr. Mohammad Hoesin General Hospital, Palembang, Indonesia Sri Handayani; Partan, Radiyati Umi; Zen Hafy; Fitri Octaviana; Citra Ananta Avis; Rini Nindela; Selly Marisdina
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 7 No. 12 (2023): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v7i12.949

Abstract

Background: In epilepsy patients, treatment is often lifelong and anti-epileptic drugs (AEDs) can be divided into two general groups, namely drugs that affect cytochrome P-450 (CYP-450) such as carbamazepine, phenytoin, primidone, or valproic acid, and those that affect minimal cytochrome P-450 such as gabapentin, vigabatrin, levetiracetam, oxcarbazepine, or topiramate. AEDs include various drugs that can cause a decrease in vitamin D levels. Therefore, this study was aimed at examining vitamin D levels in epilepsy patients who took AEDs at the neurology polyclinic at Dr. Mohammad Hoesin General Hospital, Palembang, Indonesia. Methods: This research is a descriptive study with a cross-sectional design using primary data obtained from the results of patient examinations using laboratory tests and secondary data from medical records. Results: As many as 78% (14 subjects) who received monotherapy had vitamin D levels below normal, and 16 subjects, or 76%, who received polytherapy had vitamin D levels below normal (p = 0.907). A total of 13 (72%) subjects who received phenytoin had vitamin D levels below normal, as well as 5 (63%) subjects who received carbamazepine and 12 (92%) subjects who received other therapies (p = 0.235). A total of 12 (67%) subjects who received therapy for 1-3 years and 18 (86%) subjects who received therapy > 3 years had vitamin D levels below normal (p = 0,406). Conclusion: Vitamin D deficiency is a crucial problem in epilepsy patients receiving AED therapy, where more than 75% of patients have vitamin D deficiency. In this study, vitamin D deficiency did not have a significant relationship with the type of therapy (monotherapy or polytherapy) or the type of drug used. used, duration of therapy, and frequency of sun exposure.