Article Per Year (5 Year)
p-Index From 2021 - 2026
1.896
P-Index
This Author published in this journals
All Journal Sari Pediatri Paediatrica Indonesiana AcTion: Aceh Nutrition Journal Jurnal Prima Medika Sains JKKI : Jurnal Kedokteran dan Kesehatan Indonesia Journal of Health and Nutrition Research
Heru Noviat Herdata, Heru Noviat
Unknown Affiliation
Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

Published : 12 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 12 Documents
Search

 1   2 
Correlation between Platelet Indices and PELOD-2 Score as Prognostic Markers in Pediatric Sepsis at Dr. Zainoel Abidin Hospital Pratiwi, Sari Novita; Sovira, Nora; Edward, Eka Destianti; Herdata, Heru Noviat; Safri, Mulya; Ismy, Jufitriani
Journal of Health and Nutrition Research Vol. 4 No. 3 (2025)
Publisher : Media Publikasi Cendekia Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56303/jhnresearch.v4i3.613

Abstract

To determine the correlation between Mean Platelet Volume (MPV) and Platelet Distribution Width (PDW) with Pediatric Logistic Organ Dysfunction (PELOD-2) scores as prognostic markers in pediatric sepsis. This prospective cohort study included 44 pediatric sepsis patients admitted to the PICU at Dr. Zainoel Abidin Hospital from July to September 2024. PELOD-2 scores and blood indices were assessed on admission (Day 1) and Day 3. Pearson correlation was used to analyze the relationship between variables. The majority of patients were female (59.1%) and under one year old (31.8%). By Day 3, 68.2% of patients exhibited MPV levels exceeding 10.4 fL. Significant moderate correlations were found between Day 3 MPV and PELOD-2 (r=0.410; p=0.006), Day 3 PDW and PELOD-2 (r=0.518; p=0.001), and the changes ($\Delta$) in PDW versus PELOD-2 scores (r=0.471; p=0.005). Increases in MPV and PDW are significantly correlated with PELOD-2 scores, suggesting their potential utility as accessible prognostic markers in pediatric sepsis management.
Profile and outcome of atypical progressive acute kidney injury in children in a tertiary care hospital in Indonesia Fitria, Fitria; Sovira, Nora; Haris, Syafruddin; Yusuf, Sulaiman; Herdata, Heru Noviat; Ismy, Jufitriani
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 17, No 1, (2026)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol17.Iss1.art8

Abstract

Background: Atypical progressive acute kidney injury (APAKI) in children is a severe form of acute kidney injury (AKI) marked by rapid progression to end-stage and high mortality. Since August 2022, Indonesia has reported a surge of pediatric AKI, predominantly in previously healthy children, linked to contamination of syrup medications with diethylene glycol (DEG) and ethylene glycol (EG).Objective: The objective of this research is to identify the characteristics and clinical outcomes of children with APAKI at Dr. Zainoel Abidin Hospital in Banda Aceh, a tertiary care hospital in Indonesia.Methods: This analytical observational study used secondary data from pediatric medical records of APAKI cases between June and December 2022. A total sampling technique identified 31 eligible patients aged 1–18 years old. Clinical characteristics, laboratory parameters, and outcomes were analyzed using descriptive statistics and Fisher’s Exact tests.Results: Thirty-one pediatric patients with APAKI are included; most are male (64.5%), aged 1–5 years (93.5%), domiciled outside Banda Aceh (58.1%), and had good nutritional status (80.6%). The mortality is high (74.2%). Genitourinary symptoms such as oliguria/anuria are the most frequent (87.1%), and dialysis is the main therapy (64.5%). Poor outcomes are significantly associated with respiratory symptoms (OR=16; 95%CI: 1.643-155.77), PELOD-2 score ≥10 (OR=10.89; 95%CI: 1.140-103.98), and mechanical ventilation (OR=16; 95%CI: 1.643-155.77). Laboratory predictors of mortality included leukocytosis (OR=11.11; 95%CI: 1.701-72.564), thrombocytopenia (OR=1.90; 95%CI: 1.207-2.957), elevated urea (OR=13.2; 95%CI: 1.124-154.920), elevated creatinine (OR=36.67; 95%CI: 3.124-430.333), reduced eGFR (OR=22; 95%CI: 1.924-251.539), and elevated SGOT (OR=22; 95%CI: 1.924-251.539) and SGPT (OR=36.67; 95%CI: 3.124-430.333). Toxicology testing is correlated with better survival (OR=0.07; 95% CI: 0.006-0.889).Conclusion: APAKI in children is associated with high mortality. Poor outcomes are strongly linked to respiratory involvement, high PELOD-2 scores, mechanical ventilation, and multiple laboratory abnormalities, highlighting the importance of early risk identification and timely management.
Co-Authors Akbar, Zaki Amna, Eka Yunita Anidar Anidar, Anidar Arsa, Iwan Sabardi Bakhtiar Bakhtiar Darnifayanti, Darnifayanti Dora Darussalam, Dora Edward, Eka Destianti Eka Destiani, Eka Fariyasni, Fariyasni Fiska, RR. Rima Aulia Fitria Fitria Herlina Dimiati, Herlina Ismy, Jufitriani Kowita, Nurul Huda Machya, Farish Mulya Safri, Mulya Munawarah, Syifa Nora Sovira, Nora Nuriyanto, Alivia Rizky Pratiwi, Sari Novita Rahmi, Nurul Maulina Rusdi Andid, Rusdi Safana, Garsia Sovira, Sovira sufriani, sufriani Sulaiman Yusuf Syafruddin Haris, Syafruddin Taufani, Veria Thaib, Teuku Muhammad Tita Menawati Liansyah Zakaria, Iskandar