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Evaluasi Tingkat Pengetahuan, Sikap dan Tindakan Ibu Pemberdayaan dan Kesejahteraan Keluarga Terkait Penggunaan Antibiotika di Kecamatan Kubu Karangasem Bali: Evaluation of the Level of Knowledge, Attitudes, and Actions of Empowerment and Family Welfare Mothers Related to the Use of Antibiotics in the Kubu Sub-District Karangasem Bali Luh Anggi Distya Pratiwi; Dita Maria Virginia; Nunung Priyatni
Jurnal Surya Medika (JSM) Vol. 10 No. 3 (2024): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v10i3.8984

Abstract

Antibiotika merupakan golongan obat yang paling banyak digunakan di dunia terkait dengan banyaknya kejadian infeksi bakteri. Kurangnya pengetahuan tentang penyakit dapat menyebabkan kesalahan pemilihan obat yang digunakan untuk terapi. Salah satu kurangnya pengetahuan masyarakat yaitu terkait dengan kerasionalan penggunaan antibiotika. Penelitian ini dilakukan untuk mengetahui pengaruh metode seminar terhadap pengetahuan, sikap dan tindakan ibu pemberdayaan dan kesejahteraan keluarga terkait antibiotika di Kecamatan Kubu Karangasem Bali. Penelitian ini merupakan penelitian Analytical Quasi Experimental dengan rancangan two group pre-post test. Pengambilan sampel dilakukan secara purposive sampling melibatkan 84 responden yang dibagi dengan 42 responden pada kelompok kontrol dan 42 responden pada kelompok perlakuan. Data untuk penelitian terkait peningkatan pengetahuan, sikap dan tindakan diperoleh melalui pengisian kuesioner pretest, posttest I, posttest II, dan posttest III. Uji hipotesis pada kelompok perlakuan ini dilakukan untuk membandingkan nilai pretest dengan posttest I, pretest dengan posttest II, pretest dengan posttest III dalam aspek pengetahuan, sikap dan tindakan pada semua dimensi yaitu pada kelompok kontrol aspek pengetahuan dengan nilai 0,726 (pre-post I), 0,558 (pre-post II), 0,533 (pre-post III). Aspek sikap 0,463 (pre-post I), 0407 (pre-post II), 0,543 (pre-post III). Aspek tindakan 0,789 (pre-post I), 0,408 (pre-post II), 0,496 (pre-post III). Hasil yang diperoleh yaitu p > 0,05 yang artinya tidak ada perbedaan yang bermakna pada kelompok kontrol. Sedangkan pada kelompok perlakuan memperoleh nilai pada aspek pengetahuan dan sikap 0,000 (pre-post I, pre-post II, pre-post III). Aspek tindakan 0,000 (pre-post I), 0,003 (pre-post II), 0,011 (pre-post III). Hasil tersebut memperoleh nilai p < 0,05 yang artinya adanya perbedaan bermakna. Kesimpulan dalam penelitian ini adalah adanya intervensi dengan metode seminar mengakibatkan adanya peningkatan terhadap pengetahuan, sikap dan tindakan responden terkait dengan antibiotika.
Cost-effectiveness Study in Type 2 Diabetes Mellitus in Asia: A Review Wiracana, I Made; Priyatni, Nunung; Virginia, Dita Maria
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 14, No 4
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.92720

Abstract

Background: Type 2 Diabetes Mellitus (DM) requires intensive treatment to prevent progression and complications. One of the intensive treatments is insulin therapy. The increase in insulin price and variation in insulin therapy results in differences in treatment costs. In Asia, commonly used types of insulin therapy are NPH insulin and glargine insulin. It is urgent to define the most cost-effective insulin therapy among type 2 DM patients because of the economic burden.Objectives: This study aims to assess the cost-effectiveness of these insulin types. We did a narrative review using literature discussing the cost-effectiveness of insulin for type 2 DM patients.Methods: This study employs a narrative review approach using the PRISMA-P 2015 structured approach to examine studies. This article's methodological quality was evaluated using the Drummond checklist. The terms "cost-effectiveness analysis," "diabetes mellitus type 2," and "insulin" were used in the literature search for this study.Results: We obtained five pieces of literature fulfilling inclusion and exclusion criteria. The results indicated that the age range of type 2 DM patients in this study is 57-62 years, with a majority being women. The most frequently occurring complication is cardiovascular complications. NPH insulin and glargine insulin were the most extensively studied insulins in the literature review.Conclusion: Based on the cost-effectiveness analysis, glargine insulin is more cost-effective than NPH insulin in Asia due to the rare occurrence of hypoglycemia which is a common side effect as a treatment outcomes.
The impact of medication adherence on health outcomes for patients with metabolic syndrome Setiawan, Christianus Heru; Virginia, Dita Maria; Pinaryanto, Kartono; Sari, Lisa Kurnia; Hendra, Phebe
JURNAL ILMU KEFARMASIAN INDONESIA Vol 22 No 1 (2024): JIFI
Publisher : Faculty of Pharmacy, Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/jifi.v22i1.1378

Abstract

Cardiovascular disease is a non-communicable disease that is often associated with metabolic syndrome (MetS). MetS is a group of abnormal conditions that include hypertension, obesity, and diabetes. Patients with MetS often require multiple drugs to achieve therapeutic targets, but poor medication adherence can lead to complications. Poor medication adherence can worsen the disease and increase hospitalizations. The purpose of this study was to investigate whether medication adherence affects metabolic syndrome outcomes. This study was conducted using a cross-sectional design and purposive sampling. Our respondents were focused on patients with hypertension, diabetes mellitus, or dyslipidemia. Patients' adherence was measured using a self-made questionnaire. The study obtained data on the patient's lipid profile, HbA1c, and blood pressure (hypertension, diabetes, or dyslipidemia). The study used Spearman analysis to investigate adherence scores to lipid profile levels, HbA1c, and blood pressure. Therapeutic coverage was analyzed using a T-test. Confounding variables, such as age, HbA1c level, and blood pressure, were considered when analyzing the correlation between adherence scores and lipid profiles. The majority of patients were women or elderly, and more than 90% reported that their therapeutic needs were met. Total cholesterol and LDL-c significantly negatively correlated with adherence for patients' factor category, therapeutic regimen factor, and overall factor (p<.05). Triglyceride levels correlated significantly with adherence only to category interaction factors between patients and family/health workers. Regression analysis shows that all correlations are negative to total cholesterol, LDL, HDL, and triglyceride levels (p<.05).
The Effect of Adherence to Antihypertensive Therapy and Cardiovascular Risk Among Hypertensive Patients in Purworejo Regency Arwinda, Prili; Virginia, Dita Maria; Hendra, Phebe
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 21, No 2 (2024)
Publisher : Sanata Dharma University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24071/jpsc.007334

Abstract

Uncontrolled hypertension will increase mortality and morbidity rates. The adherence is an important factor in controlling blood pressure. Uncontrolled blood pressure will affect cardiovascular risk. Therefore, hypertensive patients must comply with taking medication to control blood pressure and cardiovascular risk. This study was an analytical observational study with a cross-sectional design. A total of 85 respondents who met the inclusion criteria were measured for adherence using the MPR (Medication Possession Ratio) method and the MARS-5 (Medication Adherence Report Scale-5) questionnaire.  A patient who had blood pressure 140/90 mmHg was categorized as controlled hypertension. The cardiovascular risk was measured using the ACC/AHA criteria method. Data were analyzed using chi-square tests and odds ratio (OR) with 95% confidence interval (CI) and p0.05 considered significant. This study showed that there was a significant association between adherence to antihypertensive therapy to controlled blood pressure, either according to MPR (OR=18.262; 95%CI=5.259-63.412; p=0.000) and MARS-5 (OR=31.607; 95%CI=8.170-122.277; p=0.000). A significant association was found between antihypertensive adherence and cardiovascular risk, either according to MPR (OR=3.733; 95%CI=1.269-10.983; p=0.020) and MARS-5 (OR=9.000; 95%CI=2.702-29.983; p=0.000). Therefore, this study concludes a significant relationship between antihypertensive adherence to controlled blood pressure and cardiovascular risk in Purworejo Regency.
INTENSIFIKASI DAN KETAATAN TERAPI ANTIHIPERTENSI PADA PASIEN GERIATRI DI RSUD X BALI Asri, Ni Komang Intan Prima; Virginia, Dita Maria
Jurnal Farmasi Higea Vol 17, No 1 (2025)
Publisher : STIFARM Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52689/higea.v17i1.700

Abstract

Hipertensi merupakan salah satu penyakit kronis yang umum di Indonesia, dengan prevalensi yang terus meningkat terutama pada kelompok usia lanjut. Kasus hipertensi di Provinsi Bali mengalami peningkatan dari sejak tahun 2013. Hal tersebut menunjukkan urgensi penanganan yang lebih baik pada kelompok geriatri. Penelitian ini bertujuan untuk menganalisis pengaruh intensifikasi dan ketaatan terapi antihipertensi terhadap terkontrolnya tekanan darah pada pasien geriatri di RSUD X Bali. Metode penelitian yang digunakan adalah analisis kuantitatif dengan desain cross-sectional. Data dikumpulkan melalui rekam medis meliputi pengukuran tekanan darah dan riwayat terapi antihipertensi, serta dianalisis menggunakan uji Chi-square. Hasil penelitian menunjukkan bahwa tidak terdapat pengaruh yang signifikan secara statistik antara intensifikasi terapi (OR = 0,290; 95% CI, 0,051-1,639; p-value = 0,143) dan ketaatan terapi (OR = 1,214; 95% CI, 0,427-3,452; p-value = 0,716) terhadap terkontrolnya tekanan darah pasien. Meskipun analisis statistik menunjukkan tidak ada hubungan signifikan, ketaatan terapi tetap dianggap penting karena sebagian besar pasien yang mematuhi terapi menunjukkan tekanan darah terkontrol. Pendekatan yang lebih personal dan komprehensif, termasuk edukasi pasien dan pemantauan yang teratur, tetap penting dalam pengelolaan hipertensi pada pasien geriatri.  
The Relationship of Medication Adherence to Controlled HbA1c and ASCVD Risk in Type II Diabetes Mellitus Patients in Minggir Primary Health Care Dewita, Aquina Nino Rama Dhanti; Hendra, Phebe; Virginia, Dita Maria
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 22, No 1 (2025)
Publisher : Sanata Dharma University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24071/jpsc.007464

Abstract

Type II diabetes mellitus (DM) therapy can be evaluated from the controlled HbA1c. Another aspect that needs to be controlled in patients with DM is lipid levels. Lipid levels should be controlled in a patient with type II DM to prevent atherosclerotic cardiovascular disease (ASCVD). The study was conducted to determine the relationship between medication adherence with controlled HbA1c and ASCVD risk in patients with type II DM. The study was an analytical observational study with a cross-sectional research design used to examine the relationship between medication adherence with controlled HbA1c and ASCVD risk. Our respondents were patients following a chronic disease management program at Minggir Primary Health Care. The level of medication adherence was measured using the Medication Adherence Report questionnaires. The ASCVD risk was measured using the American College of Cardiology/American Heart Association tools. The chi-squared test was applied to determine the relationship between medication adherence with HbA1c values and ASCVD risk in patients with type II DM. Most patients with type II DM had high medication adherence (60%), controlled HbA1c values (56.4%), and high ASCVD risk (70.9%). There was no significant relationship between medication adherence in type II DM patients with controlled HbA1c values and ASCVD risk.
Peningkatan Pengetahuan Tentang Gizi dan Stunting di Wonosari, Gunungkidul, DIY: Improving Knowledge of Nutrition and Stunting in Wonosari, Gunungkidul, DIY Virginia, Dita Maria; Wakitha, Stephanus Satria Wira; Immanuel, Handika; Rohmahtika, Amanda; Travita, Anggi Silva; Djunaedi, Jeniffer Kalyana Paramita; Jannah, Widyatul; Pero, Veronika Giuliany
Jurnal Pengabdian Kepada Masyarakat: Kesehatan Vol. 5 No. 1 (2025): Maret
Publisher : Sekolah Tinggi Ilmu Kesehatan Notokusumo Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Abstrak: Stunting merupakan problem kesehatan masyarakat yang belum dapat dituntaskan. Stunting dipengaruhi oleh minimnya pengetahuan mengenai stunting dan gizi yang baik untuk pencegahan stunting. Program pengabdian bertujuan untuk  pemahaman masyarakat tentang pentingnya asupan gizi seimbang dan suplementasi vitamin dalam mencegah stunting. Angka stunting di Desa Baleharjo masih tinggi. Metode kegiatan pengabdian berupa participatory action service karena melibatkan Puskesmas Wonosari II dengan wilayah kerja Desa Baleharjo, Wonosari. Kegiatan berupa penyuluhan kepada kader dan ibu yang memiliki anak balita serta terdapat kegiatan pendampingan untuk ibu dan anak. Hasil penyuluhan menunjukkan pengetahuan mengenai (1) hal yang harus dilakukan pada periode 1000 HPK (p-value=0,00) dan (2) nutrisi terbaik pada MPASI untuk mencegah stunting (p-value=0,02), meningkat secara signifikan. Pengetahuan lain tidak terdapat peningkatan secara signifikan. Saran untuk pengabdian selanjutnya perlu mempertimbangkan pendampingan secara langsung dari waktu ke waktu dengan meningkatkan peran kader. Kegiatan pengabdian selanjutnya juga perlu mempertimbangkan pengukuran terhadap luaran utama berupa penurunan angka stunting ataupun perubahan perilaku.   Abstract: Stunting is a public health problem that has not been resolved. Stunting is influenced by the lack of knowledge about stunting and good nutrition to prevent stunting. The community service program aimed to provide community knowledge related to the importance of balanced nutritional intake and vitamin supplementation in preventing stunting. The stunting rate in Baleharjo Village is still high. The community service activity method was participatory action service because we involved the Wonosari II Health Center which their working area is ??Baleharjo Village, Wonosari. Activities included counseling for cadres and mothers who have a children aged below 5 years old, and there were mentoring activities for mothers and children. The results of the counseling showed that knowledge about (1) things should to do in the 1000 FDB period (p-value = 0.00) and (2) the best nutrition in MPASI to prevent stunting (p-value = 0.02), has increased significantly. Other knowledge did not increase significantly. Suggestions for further community service need to consider direct mentoring from time to time by increasing the role of cadres. It should consider the measurement of primary outcomes such as the reduction in the number of stunted children or behavioral changes.