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All Journal Global Medical and Health Communication Universa Medicina Jurnal Dharma Bhakti Ekuitas Bioscientist : Jurnal Ilmiah Biologi JKKI : Jurnal Kedokteran dan Kesehatan Indonesia Jurnal Pengabdian Nasional (JPN) Indonesia Jurnal Kedokteran Meditek
Eveline Margo, Eveline
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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Management of anemia among patients in intensive care units Margo, Eveline
Universa Medicina Vol 27, No 2 (2008)
Publisher : Faculty of Medicine, Trisakti University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2008.v27.78-86

Abstract

Anemia is frequently encountered in critically-ill patients in the intensive care unit (ICU). Anemia may occur both at the time of admission, during treatment and after discharge from the ICU. The causes are multifactorial and include acute blood loss, blood loss from diagnostic testing and blunted red blood cell production. Blood transfusions are frequently given to patients in the ICU to treat low hemoglobin levels due to either acute blood loss or subacute anemia associated with critical illness. Although blood transfusion is a life-saving therapy, evidence suggests that it may be associated with an increased risk of morbidity and mortality. A feature of anemia of critical illness is lack of appropriate elevation of circulating erythropoietin concentrations in response to physiological stimuli. One important concern is that anemia may not be well tolerated by a critically ill patient. A number of blood conservation strategies exist that may mitigate anemia in hospital patients and limit the need for transfusion. These strategies include the use of hemostatic agents, hemoglobin substitutes and blood salvage techniques, the reduction of blood loss associated with diagnostic testing, the use of erythropoietin and the use of restrictive blood transfusion triggers. In this article we review the prevalence of anemia during critical illness specifically among patients in the ICU, and discuss the various factors that contribute to its development, the prevention and treatment of anemia by appropriate red cell transfusion and the place of erythropoietin in treatment.
Hypoglycemic effect of Phaleria macrocarpa (Scheff.) Boerl dry extract in healthy adults Meiyanti, Meiyanti; Margo, Eveline; Pusparini, Pusparini; Merijanti, Lie Tanu; Lesmana, Alvina
Universa Medicina Vol 37, No 3 (2018)
Publisher : Faculty of Medicine, Trisakti University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (828.359 KB) | DOI: 10.18051/UnivMed.2018.v37.195-202

Abstract

BackgroundThe prevalence of diabetes in Indonesia continues to increase and causes many complications. Fruits of Phaleria macrocarpa (Scheff.) Boerl. (PM) are used in the traditional health system of the Indonesians, as effective remedy in the management of diabetes mellitus. The aim of this study was to evaluate the effect and magnitude of doses of PM dry fruit extract (PME) on blood glucose levels in healthy adults.MethodsThis research was of pre-posttest design involving 30 healthy volunteer subjects aged 20-55 years receiving glucose loads. At pre-test the subjects were given orally 75 g glucose, and at post-test they were given PME at doses of 125 mg and 250 mg. Data collection included anthropometric examination and blood glucose level. The area under the curve (AUC) of blood glucose levels was measured at 0, 15, 30, 60, 120 and 180 minutes. Data analysis was performed using paired t-test with p <0.05.ResultsThe percentage of reduction in AUC between pre- and post-test after administration of PME 125 mg was 12.1% and significant (p=0.000). But the percentage of reduction in AUC between pre- and post-test after administration of PME 250 mg was 4.07% and not significant (p=0.06). The reduction in AUC between post-test PME 125 mg vs PME 250 mg showed significant results (p=0.011).Conclusion This study demonstrated that a dose of 125 mg Phaleria macrocarpa (Scheff.) Boerl. dry extract has a hypoglycemic effect in healthy adults, and may therefore be suitable for use as traditional anti-diabetic drug.
Smoking Habit and Coffee Consumption with Gastritis Incidence Rate at Productive Ages Wibowo, Elsi Septira; Margo, Eveline
Global Medical & Health Communication (GMHC) Vol 12, No 2 (2024)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v12i2.12299

Abstract

Gastritis is a disease caused by an inflammation of the mucous and submucosal lining of the stomach. Several studies show that there is an influence of smoking habit and coffee consumption on gastritis incidence rate. The study was to determine the correlation between smoking habit and coffee consumption toward gastritis at productive ages. The research is an analytical observational study with a cross-sectional design conducted in Makale Health Center, South Sulawesi, in February 2020. Required data was gathered by conducting guided interviews using a questionnaire that includes age range, sex, and education level. Brinkman Index was used to measure smoking habits, coffee consumption, and gastritis questionnaire. Data was analyzed using a chi-square test with a significance level of p=0.05. From a total of 115 respondents, there are 69.6% included in the age range of 26–35 years old, 58.3% have mild smoking habits, 56.5% have severe coffee consumption, and 85.2% are suffering from gastritis. There is a relation between smoking habit (p=0.029) and coffee consumption (p=0.003) with gastritis (p<0.05). The conclusion is that there is a relationship between smoking habits, coffee consumption, and gastritis incidence.
Edukasi Kesehatan untuk Meningkatkan Kualitas Hidup Pada Kelompok Lanjut Usia Meiyanti; Yohana; Margo, Eveline; Kartadinata, Erlani; Sisca; Hartanti, Monica Dwi
Jurnal Pengabdian Nasional (JPN) Indonesia Vol. 5 No. 2 (2024): Mei
Publisher : Lembaga Penelitian dan Pengabdian Kepada Masyarakat (LPPM) STMIK Indonesia Banda Aceh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35870/jpni.v5i2.765

Abstract

The increase in the elderly population raises concerns regarding the potential lack of understanding of chronic illnesses in this age group and their impact on quality of life. The main objective of this initiative is to provide education on a better understanding of the health issues faced by the elderly and how to manage them effectively. The study was conducted in November 2023 with 25 participants involved: 1) Preparing educational materials, 2) Providing education to elderly caregivers, and 3) Evaluating the impact of these activities through pre-and post-tests. As a result of the study, an increase in knowledge about various health problems and strategies to improve the quality of life of the elderly was observed after receiving education. As part of this activity, health status examinations were conducted, and the quality of life of elderly individuals was assessed using questionnaires. It was found that 52% of the participants reported suffering from hypertension, heart disease, or metabolic endocrine diseases. It is worth noting that the physical domain had the lowest quality-of-life score compared to other domains. In conclusion, it could be argued that community health education activities may play a crucial role in enhancing the quality of life of the elderly by equipping them with the necessary knowledge and skills to manage their health challenges
Edukasi Penanganan Nonfarmakologi Nyeri Otot Kronis Margo, Eveline; Kartadinata, Erlani; Meiyanti; Yohana; Murthi, Aditya
Jurnal Pengabdian Nasional (JPN) Indonesia Vol. 5 No. 3 (2024): September
Publisher : Lembaga Penelitian dan Pengabdian Kepada Masyarakat (LPPM) STMIK Indonesia Banda Aceh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35870/jpni.v5i3.923

Abstract

Chronic pain can result from various clinical conditions and may persist for more than three months. The symptoms can range from mild to severe. While chronic pain can be associated with various diseases, its exact cause sometimes remains unclear. In 2019, data from the National Health Interview Survey in the United States indicated that approximately 1 in 5 adults experienced chronic pain, with over 7% frequently limiting their activities due to this condition. However, there is no comparable data available for Indonesia. Chronic pain restricts activities and can decrease a person’s quality of life. Various options are available for pain management, one of which is non-pharmacological therapy, including hot-cold compresses, massage and stretching techniques, music therapy, and aromatherapy. These therapies aim to improve bodily function, regulate emotions, reduce weakness, stress, and anxiety, and decrease the need for pain medication. Gout is among the most common causes of chronic pain, with a prevalence of 3.9% in the US, 2.5% in Europe, and 7.3% in Indonesia, according to Riskesdas (2018). Based on this, local citizens were provided with education about pain management. This community service activity involved educating citizens on non-pharmacological treatments for chronic pain management and offering health services to residents of Angke. The purpose was to increase knowledge about non-pharmacological treatments for managing chronic pain. This activity was conducted on April 27th, 2024, from 07.00 to 12.00 at the Dhammasavana School in the Angke sub-district area, West Jakarta. The activities proceeded smoothly and in an orderly manner. A comparison of citizens’ knowledge before and after the education revealed a 58.18% increase in knowledge, contributing to improved welfare among the local residents.
Hubungan Dukungan Sosial dan Nyeri Melahirkan dengan Risiko Baby Blues pada Ibu Bersalin Usia Dini Rachmadanti, Tharisa; Margo, Eveline
Jurnal Kedokteran Meditek Vol 30 No 3 (2024): SEPTEMBER
Publisher : Fakultas Kedokteran Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jkdoktmeditek.v30i3.3256

Abstract

Pernikahan dini mayoritas terjadi di negara berkembang, data Badan Pusat Statistik menyatakan angka kelahiran ibu muda terjadi di usia 15–19 tahun di Indonesia. Perubahan fisik dan emosional postpartum merupakan penyebab terjadinya baby blues. Menurut WHO (2014) angka kejadian baby blues berkisar 50–70 %. Penyebabnya dari berbagai faktor, di antaranya dukungan sosial dan nyeri melahirkan. Tujuan penelitian ini adalah untuk mencari hubungan dukungan sosial dan nyeri melahirkan dengan risiko baby blues pada ibu bersalin usia dini. Penelitian dilakukan di Kecamatan Muara Padang, Sumatera Selatan dengan rancangan potong lintang. Teknik pengambilan sampel menggunakan metode random sampling. Penelitian dilakukan antara bulan Agustus - November 2022, didapatkan 84 subjek yang berumur antara 15–19 tahun, melahirkan dalam 1 minggu dan bersedia mengikuti penelitian. Penilaian dukungan sosial memakai kuesioner Berlin Social Support Scale, untuk menilai nyeri melahirkan memakai Numerical Rating Scale dan Edinburgh Postpartum Depresion Scale untuk menilai risiko baby blues. Analisis data menggunakan uji Chi-square (p<0,05). Hasil penelitian didapatkan tidak berhubungan signifikan antara dukungan sosial dengan risiko baby blues (p0,235), sedangkan untuk nyeri melahirkan berhubungan signifikan dengan risiko baby blues (p0,001). Kesimpulannya tidak terdapat hubungan antara dukungan sosial dengan risiko baby blues dan terdapat hubungan antara nyeri melahirkan dengan risiko baby blues.
mRNA Relative Expression Catalase in Hypertension Yohana, Yohana; Faradilla, Meutia Atika; Meiyanti, Meiyanti; Hartanti, Monica Dwi; Margo, Eveline; Anastasya, Karina Shasri
Bioscientist : Jurnal Ilmiah Biologi Vol 12, No 2 (2024): December
Publisher : Department of Biology Education, FSTT, Mandalika University of Education, Indonesia.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33394/bioscientist.v12i2.12825

Abstract

Hypertension is number one worldwide disease which lead to death. Initially hypertension is caused by changes in the walls of blood vessels. These vascular changes are due to the accumulation of ROS (Reactive Oxygen Species). ROS is the result of the balance between antioxidants and oxidants, but uncontrolled conditions will cause vascular damage. One of ROS product from metabolism which could played role in downregulation antioxidant gene expression is hydrogen peroxide. Hydrogen peroxide could be neutralized by catalase enzyme. Studies about catalase expression in hypertension subject is still limited. This research aims to determine mRNA relative expression catalase in hypertension. In this case control study, thrity subject hypertension and normotension subject were recruited within the age of 50-60 years. Hypertension subject was chosen according to JNC 8. Two millilitres vein blood was isolated into RNA. mRNA expression was detected by qRT PCR with 2 steps. Relative expression was determined using livak method. The data was analyzed using Mann Withney test with GraphPad software. Research results show that (1) catalase mRNA relative expression was 0,6 fold in hypertension; (2) catalase relative expression was not significantly lower in hypertension; (3) other antioxidants might have other mechanism to detoxify ROS and prevent hypertension.
Evaluasi Pengukuran Glukosa Darah Puasa dan Asam Urat pada Lanjut Usia di Kelurahan Angke, Jakarta Barat Yohana, Yohana; Meiyanti, Meiyanti; Margo, Eveline; Kartadinata, Erlani
Jurnal Dharma Bhakti Ekuitas Vol. 7 No. 2 (2023): Jurnal Dharma Bhakti Ekuitas
Publisher : STIE Ekuitas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52250/p3m.v7i2.644

Abstract

Diabetes mellitus is a chronic disease that correlate with aging. The manifestation of aging is decreasing pancreas function which caused glucose metabolism disorder. According to RISKESDAS in 2018, the prevalence rate diabetes mellitius type 2 in Indonesia is about 8,5%. A previous study found that increasing age correlated with glucose metabolic alteration. Our study found that prevalence of diabetes mellitus type 2 in older people about 19% at Angke, Jakarta Barat. Thus, our service aims of increasing heath status and identifying the risk of chronic disease. This project was held in Dhammasava High School on Sunday, January 8th, 2023, and it was followed around by 50 people. Consultation, anthropometric measurement and laboratory examination were done by the faculty of medicine Trisakty University associate. Our result found that 54% people have overweight, 48% people have hyperglycemia and 58% people have hyperuricemia. Heatlh status was evaluated favorably caused normal and disorder groups not significantly different. Suprisingly prevalence of chronic disease in Angke area is soaring, so either promotive and prevention or treatment would impact health status and condition. Keyword: Body mass index, diabetes mellitus, hyperglycemia, hyperuricemia. Abstrak Diabetes mellitus adalah penyakit kronis yang berhubungan dengan proses penuaan. Salah satu tanda penuaan adalah penurunan fungsi organ pankreas yang menyebabkan gangguan metabolisme glukosa. Data RISKEDAS 2018 menunjukan prevalensi diabetes melitus tipe 2 sebesar 8,5%. Studi terakhir menunjukan penambahan usia memiliki korelasi terhadap perubahan metabolisme glukosa. Pada pengabdian sebelumnya didapatkan lanjut usia di kelurahan Angke memiliki angka kejadian diabetes meliitus sebesar 19%. Pengabdian ini bertujuan untuk meningkatkan status kesehatan dan melakukan skrining terhadap resiko penyakit kronis. Kegiatan dilakukan di Sekolah Dhammasavana pada hari Minggu, 8 Januari 2023 dan dikuti 50 orang peserta. Konsultasi, pengukuran antropometri tubuh, dan pemeriksaan laboratorium sederhana dilakukan secara personal oleh tim pengabdian fakultas kedokteran Universitas Trisakti. Hasil pengabdian menunjukan terdapat 54% peserta mengalami berat badan lebih (overweight), 48% peserta mengalami hiperglikemia, dan 58% peserta mengalami hiperurisemia. Status kesehatan peserta dinilai masih cukup baik oleh karena perbandingan peserta yang memiliki kelainan dan normal tidak berbeda bermakna. Prevalensi penyakit kronis pada peserta didapatkan cukup tinggi, kondisi penyakit yang mempengaruhi tingkat kesehatan sehingga perlu dilakukan tindakan promotif maupun pengobatan pada kelompok masyarakat di Kelurahan Angke. Kata kunci: asam urat, diabetes melitus, glukosa darah puasa, indeks massa tubuh.
Vitamin D receptor polymorphism associated with obesity in productive age population: A cross-sectional study Yohana; Meiyanti; Hartanti, Monica Dwi; Margo, Eveline; Zuraida, Reni
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 16, No 1, (2025)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol16.Iss1.art6

Abstract

Background: Obesity is influenced by genetic factors, lifestyle, and environmental factors. This increase in obesity gives rise to various chronic disease problems.Objectives: This study aimed to identify genetic variations of Vitamin D receptors and determine the relationship to obesity in terms of body mass index and body fat percentage in the working group.Methods: This study is an analytical observational study with a cross-sectional research design approach in the Jembatan Dua area, Angke sub-district, West Jakarta. The research instrument used was a questionnaire to obtain characteristic data, as well as an examination of VDR gene variations rs1544410, rs2228570, rs7975232, and PCR examination to obtain data on gene variation.Results: The results obtained are as follows: the average age of subjects was 42.24, with 58.1% females. A total of 39 (69.1%) are Javanese. Thirty-one (50%) subjects were included in the category of obesity (BMI> 25), and 41 (66.1%) subjects were obese category based on the body fat percentage. The results of bivariate analysis obtained SNP VDR FoxI gene obtained a significant relationship with body mass index with a p-value of 0.047, while the VDR BsmI gene obtained a statistically meaningful relationship with body fat percentage with a p-value of 0.043.Conclusion: FoxI and BsmI VDR polymorphisms are associated with body mass index and body fat percentage.
Edukasi Penggunaan Tensimeter Digital pada Pemeriksaan Tekanan Darah dengan Status Gizi pada Lansia Kelurahan Angke, Jakarta Barat Yohana; Meiyanti; Margo, Eveline; Atika Faradilla, Meutia; Xavierees, Endrico; Kurniasari
Jurnal Dharma Bhakti Ekuitas Vol. 9 No. 2 (2025): Jurnal Dharma Bhakti Ekuitas
Publisher : STIE Ekuitas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52250/p3m.v9i2.950

Abstract

Abstract The prevalence of hypertension accompanied by obesity is increasing.  This not only happens in developed countries, but is also a problem in developing countries. Hypertension with obesity presents new problems in the management of hypertension.  Medical therapy alone is not enough, there must be intervention to reduce and control blood pressure, lose weight and change lifestyle. The aim of this service is to increase public awareness of high blood pressure and obesity so that it can reduce morbidity and death rates due to complications of high blood pressure. This service is carried out by checking participants' blood pressure, Body Mass Index, education and teaching participants how to use a blood pressure monitor independently at home to control blood pressure. There were 50 service participants who attended. The age range of participants is 40 to 75 years with the average age of service participants being 2.75 years. There were 35 female participants while there were 15 male participants. There were 33 participants diagnosed with high blood pressure, while 17 people with normal blood pressure. Participants diagnosed with hypertension based on JNC 8 were 66%, divided into grade 1, 72.2%, and grade 2, 27.27%. Participants' body mass index was categorized as normal at 24% and obese and/or overweight at 76%. The correlation between blood pressure and obesity was found to be significant (p<0.05). The conclusion that there was a higher rate of participants with hypertension than normal and there was a significant relationship between the risk of hypertension and obesity. Keyword: Blood Pressure, Hypertension, Obese, Body Mass Index, Elderly.   ---------------------------------------------------------------------------------------------------------------- Abstrak Hipertensi adalah penyakit degeneratif yang bersifat kronis yang mengenai pembuluh darah. Kasus hipertensi yang dipengaruhi oleh obesitas terus meningkat, tidak hanya di negara maju, tetapi juga menjadi perhatian serius di negara berkembang. Kondisi ini memerlukan strategi baru dalam pengelolaan hipertensi. Pengobatan dengan obat-obatan saja tidak memadai, diperlukan intervensi yang lebih luas untuk mengendalikan tekanan darah, menurunkan berat badan, dan mengubah gaya hidup.Tujuan pengabdian ini adalah untuk meningkatkan perubahan perilaku, sikap dan pencegahan terhadap tekanan darah tinggi dan obesitas sehingga dapat menurunkan angka kesakitan dan kematian akibat komplikasi tekanan darah tinggi. Pengabdian ini dilakukan dengan cara memeriksa tekanan darah peserta, Indeks Massa Tubuh, edukasi serta mengajarkan peserta cara penggunaan tensimeter secara mandiri dirumah untuk mengontrol tekanan darah. Peserta pengabdian yang hadir berjumlah 50 orang. Jangkauan usia peserta adalah 40 hingga 75 tahun dengan peserta lanjut usia berjumlah 42 orang.  Rerata usia peserta pengabdian ini adalah 62,75 tahun. Peserta perempuan berjumlah 35 orang sedangkan peserta laki-laki berjumlah 15 orang. Peserta yang terdiagnosa tekanan darah tinggi berjumlah 33 orang sedangkan yang normal berjumlah 17 orang. Peserta yang terdiagnosis hipertensi berdasarkan Joint National Committee (JNC) 8 sebesar 66% terbagi menjadi grade 1 sebanyak 72,2% dan grade 2 sebanyak 27,27%. Indeks massa tubuh peserta dikategorikan normal sebesar 24% dan obesitas dan atau berat badan lebih sebesar 76%. Analisa statistik untuk menentukan korelasi antara tekanan darah menggunakan software JASP 0.19.3. Data tekanan darah dan indeks massa tubuh berdistribusi normal dan menggunakan uji Pearson dengan nilai kemaknaan (p<0,05). Kesimpulan didapatkan bahwa jumlah peserta dengan hipertensi lebih tinggi dibandingkan normal dan terdapat korelasi signifikan antara risiko terjadinya hipertensi dengan normal dan terdapat korelasi signifikan antara risiko terjadinya hipertensi dengan obesitas.    Kata kunci: Tekanan darah, Hipertensi, Obesitas, Indeks Massa Tubuh, Lanjut Usia.
Co-Authors Alvina Lesmana, Alvina Anastasya, Karina Shasri Erlani Kartadinata, Erlani Faradilla, Meutia Atika Kurniasari Lie Tanu Merijanti, Lie Tanu Meiyanti Meiyanti Meiyanti, Meiyanti Monica Dwi Hartanti, Monica Dwi Murthi, Aditya Pusparini Pusparini Rachmadanti, Tharisa Reni Zuraida sisca Wibowo, Elsi Septira Xavierees, Endrico Yohana Yohana Yohana