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Effect Administration of Ethanol Extract of Bitter Melon (Momordica Charantia L.) On The Reduction of MDA (Malondialdehyde) Levels Serum in Rats Given a High-Fat Diet Andiani, Andiani; harsa, made subhawa
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 7, No 2 (2018): Edisi September 2018
Publisher : Universitas Wijaya Kusuma Surabaya

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Abstract

Hyperlipidemia is a disease whichthe effect in increased fat levels in the blood. In hyperlipidemia, the condition of high oxidative stress is obtained due to the oxidation process of LDL (Low Density Lipoprotein) in the body, this condition showed by increased of MDA (Malondialdehyde) levels in serum. Bitter melon (Momordica Charantia L.) contains a lot of active ingredients, one of the ingredients of bitter melon that is thought to have antilipidemic effects is flavonoid compounds. This study was experimental study using a randomized posttest only control group design study with a sample size of 30 male white rats (Rattus norvegicus) wistar strain which was divided into 3 groups, namely K1, K2, and K3. In each group, different treatments are given. Negative control group (K1), given standard feed, water ad libitum; Positive control group (K2), given standard feed, high fat feed with a dose of 2.5 ml water ad libitum; The treatment group (K3) was given a standard diet, high-fat feed with a dose of 2.5 ml water ad libitum and extract of bitter melonat a dose of 250 mg / kg BB by orally every morning for 3 weeks. Data analysis using One Way Anova Test. From the results of the test shows the significance of p-value = 0.000 which is <α (0.05). The results showed that there was an effect of  administration ethanol extract of bitter melon (Momordica charantia L.) to decrease in serum MDA (malondialdehyde) levels in male white wistar rats (Rattus norvegicus) given a high-fat diet.
Faktor Risiko Diabetes Mellitus Tipe 2 Pada Populasi Asia: A systematic Review Salasa, Rosfiah A.; Rahman, Hamidah; Andiani, Andiani
JURNAL BIOSAINSTEK Vol 1 No 01 (2019): Juli 2019
Publisher : UNIVERSITAS MUHAMMADIYAH MALUKU UTARA

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Abstract

Diabetes mellitus adalah penyakit kronis yang ditandai oleh hiperglikemia akibat gangguan produksi insulin, aksi insulin, atau keduanya. Diabetes melitus (DM)&nbsp; tipe 2 dikenal juga sebagai non-insulin dependent yaitu diabetes yang disebabkan oleh ketidakmampuan tubuh untuk secara efektif menggunakan insulin. Beberapa penelitian telah melaporkan bahwa faktor risiko terjadinya DM tipe 2 yaitu varian genetik (genetic varian), lingkungan (environment) dan oleh interaksi gen-lingkungan (gene-environment interaction). Tujuan dari penelitian ini adalah untuk mendata dan mengetahui faktor risiko kejadian DM tipe 2 pada populasi Asia dengan menggunakan jenis penelitian kajian sistematik (systematic review). Publikasi yang dikaji berupa hasil penelitian yang diperoleh dari lembaga pengindeks Pubmed dengan batasan waktu publikasi 5 tahun terakhir. Dari hasil penelitian ini diperoleh sebanyak 561 artikel tentang faktor risiko DM tipe 2 pada populasi Asia yang kemudian disaring dan dieliminasi dengan beberapa alasan hingga diperoleh 72 artikel yang dinilai layak untuk dikaji. Dari hasil kajian ini diketahui bahwa faktor risiko DM tipe 2 pada populasi Asia secara garis besar yaitu karena varian genetik (genetic varian), faktor lingkungan (environment) dan adanya interaksi antara gen-lingkungan (gene-environment interaction). Terdapat 24 varian genetik yang dilaporkan pada populasi Asia sebagai gen yang rentan terhadap DM tipe 2. Terdapat pula beberapa faktor lingkungan sebagai faktor risiko DM tipe 2 antara lain gaya hidup (lifestyle) dan profil antropometri. Interaksi antara gen-lingkungan juga sebagai faktor risiko terjadinya DM tipe 2, sebagai contoh antara lain interaksi antara gen dengan obesitas dan interaksi antara gen dengan merokok. Secara keseluruhan hasil kajian sistematik ini bermanfaat untuk mengetahui faktor risiko kejadian DM tipe 2 yang dapat dimodifikasi sehingga pencegahan kejadian DM tipe 2 dapat dilakukan.
Pengelolaan Limbah Medis Padat Puskesmas Cisoka Kabupaten Tangerang Ernyasih, Ernyasih; Sulastri, Siti; Andiani, Andiani
ENVIRONMENTAL OCCUPATIONAL HEALTH AND SAFETY JOURNAL Vol 4, No 2 (2024): EOHSJ
Publisher : Fakultas Kesehatan Masyarakat Universitas Muhammadiyah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24853/eohjs.4.2.19-25

Abstract

Puskesmas adalah fasilitas pelayanan kesehatan yang menyelenggarakan upaya kesehatan masyarakat dan upaya kesehatan perseorangan tingkat pertama, dengan lebih mengutamakan upaya promotif dan preventif di wilayah kerjanya. Limbah medis padat yang berasal dari sarana pelayanan kesehatan mempunyai dampak terhadap kesehatan dan lingkungan, limbah ini perlu dikelola sesuai dengan aturan yang ada sehingga pengelolaan lingkungan dilakukan secara sistematis dan berkelanjutan. Limbah medis yang tidak dikelola dengan baik dapat membahayakan kesehatan masyarakat. Hal ini disebabkan karena limbah medis mengandung virus dan kuman yang berasal dari aktivitas medis yang dilakukan di pelayanan kesehatan. Metode penelitian yang digunakan yaitu deskriptif dengan pendekatan kualitatif, pengumpulan data dengan metode wawancara mendalam, observasi, dan telaah dokumen. Analisis data yang digunakan dengan cara triangulasi sumber dan metode. Berdasarkan hasil observasi dan wawancara, pemusnahan masih belum dilakukan secara non insenerasi, karena limbah medis hanya disimpan pada tempat penyimpanan sementara menunggu pihak ketiga mengambil limbah tersebut. Pengelolaan limbah medis padat di Puskesmas Cisoka, Kabupaten Tangerang belum sesuai dengan peraturan. Puskesmas melakukan pengecekan secara berkala pada wadah limbah, apabila sudah berkarat atau tidak layak maka perlu diganti.---Community Health Center, Puskesmas is a health service facility that carries out public health efforts and first-level individual health efforts, prioritizing promotive and preventive efforts in its working area. Solid medical waste originating from health service facilities has an impact on health and the environment. This waste needs to be managed per existing regulations so that environmental management is carried out systematically and sustainably. Medical waste that is not managed properly can endanger public health. This is because medical waste contains viruses and germs that originate from medical activities carried out in health services. The research method used is descriptive with a qualitative approach, data collection using in-depth interviews, observation, and document review. Data analysis was used by triangulating sources and methods. Based on the results of observations and interviews, destruction has not yet been carried out using non-incineration, because medical waste is only stored in temporary storage areas waiting for third parties to take the waste. Management of solid medical waste at the Cisoka Community Health Center, Tangerang Regency is not following regulations. The health center carries out regular checks on waste containers, if they are rusty or unfit then they need to be replaced
Workshop Pelayanan Gizi bagi Orang dengan HIV AIDS Lestari, Tutik; Muhlis, Mudini; Yamko, Ridwan; Sumiati, Tati; Andiani, Andiani; Surasno, Diah Merdekawati; Rahayu, Agustin; Mansur, Suryani
JURNAL BIOSAINSTEK Vol 5 No 1 (2023): Jurnal BIOSAINSTEK
Publisher : UNIVERSITAS MUHAMMADIYAH MALUKU UTARA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52046/biosainstek.v5i1.1384

Abstract

Gizi yang adekuat pada ODHA dapat mencegah kurang gizi, menghambat perkembangan HIV, meningkatkan daya tahan terhadap infeksi opportunistik, memperbaiki efektifitas pengobatan dan memperbaiki kualitas hidup. Workshop ini diharapkan dapat meningkatkan pemahaman petugas gizi dalam memberikan layanan gizi untuk ODHA di Puskesmas Kota Ternate dan Rumah Sakit Chasan Boesoirie. Peserta diikuti oleh 16 peserta dengan tingkat pendidikan diploma III sebanyak 12 orang dan sarjana sebanyak 4 orang. Rata-rata peserta dapat menjawab dengan benar terkait HIV AIDS serta kebutuhan gizi bagi ODHA. Faktor pendukung kegiatan ini diantaranya adanya kerjasama dengan KPA Kota Ternate, sarana prasarana yang mendukung serta peserta tetap antusias selama 3 hari kegiatan tersebut. Peserta mampu memahami peran sebagai petugas gizi dalam melayani masalah gizi bagi ODHA.
Gambaran Pengetahuan Remaja Tentang Stunting Andiani, Andiani; Lestari, Tutik; Sumiati, Tati
JURNAL BIOSAINSTEK Vol 5 No 2 (2023): Jurnal BIOSAINSTEK
Publisher : UNIVERSITAS MUHAMMADIYAH MALUKU UTARA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52046/biosainstek.v5i2.1641

Abstract

Pemenuhan gizi pada masa anak-anak dapat menentukan banyak aspek kehidupan dikemudian hari, seperti kesehatan, prestasi, intelektualitas dan produktivitas pada masa remaja dan dewasa. Stunting merupakan salah satu indikasi kejadian kurang gizi pada anak-anak. Dikatakan pendek jika nilai z-scorenya panjang atau tinggi badan menurut umur <-2 standar deviasi, dikatakan stunted dan <-3 SD dikatakan severely stunted. Tujuan penelitian ini untuk mengetahui gambaran pengetahuan remaja tentang stunting. Penelitian ini menggunakan desain penelitian deskriptif kuantitatif, populasinya adalah siswa/i SLTP yang mengikuti kegiatan Jumpa Bakti Persahabatan IV tahun 2021 sebanyak 294 dengan jumlah sampel sebanyak 75 orang. Pengambilan sampel dilakukan dengan teknik accidental sampling. Hasil penelitian menunjukan sebagian besar tingkat pengetahuan responden termasuk dalam kategori kurang sebanyak 37 orang dan sebagian kecil kategori baik sebanyak 13 orang. Hal ini didasarkan karena remaja kurang mendapatkan informasi tentang stunting baik di lingkungan sekolah maupun tempat tinggal
Pelayanan Konseling Klinik Sanitasi Di Puskesmas Kota Ternate Togubu, Novrianti; Lestari, Tutik; Sumiati, Tati; Andiani, Andiani
DEDICATION: Jurnal Pengabdian Masyarakat Vol. 3 No. 1 (2023): 21 April 2023
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Universitas Bondowoso

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61595/dedication.v3i1.732

Abstract

Kegiatan klinik sanitasi sangat dibutuhkan oleh masyarakat namun belum maksimal karena kekurangan tenaga sanitarian dan kegiatannya hanya fokus dalam gedung. Tujuan pengabdian Masyarakat untuk peningkatan kegiatan klinik sanitasi dalam dan luar Gedung. Metodenya dengan melibatkan mahasiswa dan dosen didampingi petugas kesehatan melakukan kegiatan identifikasi masalah kesehatan, konseling, inspeksi dan intervensi. Kegiatan pengabdian masyarakat dilaskanakan selama 1 bulan di wilayah kerja Puskesmas Kota Ternate. Hasil kegiatan terdapat 4 pasien yang mendapatkan konseling, inspeksi dan intervensi dengan memberikan edukasi terkait penyakit berbasis lingkungan, tahap pertama identifikasi oleh dokter, dokter merekomendasikan pasien untuk mendapatkan pelayanan konseling. Mahasiswa didampingi petugas melakukan konseling pada pasien sesuai dengan hasil diagnosa. Hasil konseling menunjukkan bahwa ada kontak langsung dengan anggota rumah tangga lain yang memiliki gejala yang sama. Sehingga memutuskan perlu adanya
The Relationship Between Maternal Education Level and Family Income on The Incidence of Stunting in Toddlers at The Madiun City Health Center Nurwasilah, Nurwasilah; Sahadewa, Sukma; Andiani, Andiani
Jurnal Ners Vol. 8 No. 2 (2024): OKTOBER 2024
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jn.v8i2.25180

Abstract

Stunting is a condition that occurs in toddlers who experience growth failure due to chronic malnutrition based on a z-score (TB/U) value of less than -2 SD (Standard Deviation). Stunting can be caused by a low level of maternal knowledge. Family income is also a risk factor for stunting. The purpose of this study was to analyze the relationship between maternal education level and family income on the incidence of stunting in toddlers at the Madiun City Health Center. This study used an analytical observational method with a case control design. The population in this study was all mothers who had toddlers in Madiun City. Respondents in this study consisted of 34 people, obtained from questionnaires with the total sampling method. The results of Chi-Square analysis showed that there was no relationship between maternal education level (p = 0.290), no relationship between family income level (p = 0.628), maternal education level and family income level (p = 0.545) greater than p value = 0.05; showed that there was no relationship between maternal education level and family income level with the incidence of stunting in toddlers at the Madiun City Health Center. There is no relationship between maternal education level and family income with the incidence of stunting in toddlers at the Madiun City Health Center.
Description Of Community Knowledge Of Stunting In Galala Village, North Oba District, Tidore Islands City Toduho, Norma B.; Muslim, Riskal; Andiani, Andiani; Soamole, Mayasari; Alim, Riska; Armain, Rukmina; Putri, Ayu Melisa
JURNAL BIOSAINSTEK Vol 7 No 1 (2025): Jurnal BIOSAINSTEK
Publisher : UNIVERSITAS MUHAMMADIYAH MALUKU UTARA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52046/biosainstek.v7i1.2304

Abstract

The cumulative impact of stunting is longterm malnutrition and recurrent infections in early childhood, especially occurring in the first 1000 days of life. This is defined as a child's height not appropriate for his actual age or a child who has of Z Score of the height body for the age >-2 standard deviations. This research uses descriptive analysis with a cross sectional study design. The total population is 1082 heads of families. The sample in this study was 292 heads of families obtained from sample calculations using the Slovin formula (alpha 0.05). Based on the results of descriptive analysis on the knowledge variable regarding stunting, it can be concluded that 147 people (50.3%) unknow about stunting, while 145 people (49.7%) know about stunting. Then in the overall stunting score column from the analysis results it was found that 182 people (62.3%) had good knowledge of stunting and 110 people (37.7%) were in the poor category. For the information source variable, it was found that 138 people (47.3%) received stunting information from health workers/cadres, 65 people from the mass media (22.3%), 64 people (21.9%) from other people. and family/parents as many as 25 people (8.6%). So it can be concluded that community knowledge and sources of information regarding stunting still need to be improved. It is hoped that there will be community involvement and collaboration with health workers, community leaders, religious leaders in efforts to increase knowledge about stunting in Galala Village.
The Relationship Between Specific and Sensitive Nutrition Interventions and the Incidence of Stunting in Toddlers Andiani, Andiani; Lestari, Tutik; Supriyatni, Nani; Sumiati, Tati
JURNAL BIOSAINSTEK Vol 7 No 1 (2025): Jurnal BIOSAINSTEK
Publisher : UNIVERSITAS MUHAMMADIYAH MALUKU UTARA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52046/biosainstek.v7i1.2306

Abstract

Stunting, or below-standard height, is a nutritional problem commonly found in developing countries. Stunting negatively impacts growth, development, and productivity. It can increase the risk of infectious diseases, chronic diseases, and death, which will subsequently reduce work productivity in adulthood. Children who cannot catch up on growth later on can cause bigger problems, and in the future, Indonesia may experience a lost generation. Method: This study uses a descriptive-analytical method with a cross-sectional research design. The population consisted of all mothers with toddlers aged 0-59 months in 2021, totaling 520 toddlers, while the sample included 99 mothers of toddlers. Data collection on toddlers was conducted by measuring body length/height with a microtoise BB to determine stunting status and using a questionnaire. The research results were analyzed univariately and bivariately using the Chi-Square test. Results: Specific nutrition interventions, when viewed from the PMT variable (0.035), IMD counseling and exclusive breastfeeding (0.001), vitamin A capsule administration (0.022), and immunization (0.036), are related to the incidence of stunting in toddlers. Meanwhile, sensitive nutrition interventions, when viewed from the information variable (0.030) about stunting, are related to the incidence of stunting in toddlers. Conclusion: Preventing stunting requires appropriate handling through both specific and sensitive nutritional interventions together. The research results indicate that there are 5 variables related to the occurrence of stunting in toddlers, including PMT, IMD counseling and exclusive breastfeeding, administration of vitamin A capsules, immunization, and provision of information about stunting.
Environmental Health Inspection of Public Facility Locations in the Working Area of Puskesmas Gandasuli Nurintani, Nurintani; Fauzi, Murti; Lestari, Tutik; Suharto, Suharto; Andiani, Andiani; Supriyatni, Nani; Sumiati, Tati; Iriyani, Julfa Ida; Sanusi, Nurnia; Patisausiwa, Aulia
JURNAL BIOSAINSTEK Vol 7 No 1 (2025): Jurnal BIOSAINSTEK
Publisher : UNIVERSITAS MUHAMMADIYAH MALUKU UTARA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52046/biosainstek.v7i1.2351

Abstract

To ensure that the school environment remains healthy and students have healthy lifestyles, school environment inspections are necessary. According to the law, every child in Indonesia is entitled to a healthy, safe, and comfortable school environment. The goal of school health is to ensure that students' life skills can be enhanced in a healthy environment, where they can learn comfortably and grow optimally to become high-quality individuals. This community service aims to identify environmental sanitation risks in public facilities, particularly schools. The method used was direct observation of the school's condition using the previously prepared IKL form, followed by interviews with relevant parties to reinforce the findings. The results still found several schools with conditions that do not meet health standards. It is hoped that with the implementation of school environmental health inspections, the school authorities will improve in providing adequate school facilities to realize a healthy school. It is hoped that with the implementation of school environmental health inspections, the school authorities will improve in providing adequate school facilities to realize a healthy school.