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Formulation and Characterization of Soursop Leaf extract (Annona muricata L.) Nanoemulsion Using VCO and Tween 80 Puspitasari, Ratih Dyah; Sarani, Desfira; Erliana, Dina; Ekasari, Munifilia
KOVALEN: Jurnal Riset Kimia Vol. 11 No. 2 (2025): December Edition
Publisher : Chemistry Department, Mathematics and Natural Science Faculty, Tadulako University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/kovalen.2025.v11.i2.17827

Abstract

Methanol extract of soursop leaves contains various bioactive compounds such as alkaloids, saponins, tannins, and flavonoids. To increase the absorption of these compounds, a nanoemulsion formulation of soursop leaf extract was carried out. Extraction was carried out using the maceration method using 96% methanol, followed by a thickening process using a rotary evaporator and freeze drying to obtain the dry extract. The nanoemulsion preparation was made from methanol extract of soursop leaves (Annona muricata L.) using Virgin Coconut Oil (VCO) as the oil phase and Tween 80 as a surfactant. The nanoemulsion was formulated using a high-energy method using an ultrasonicator. Two formulas were tested (F1 and F2) and evaluated through organoleptic tests, clarity (transmittance), physical stability (centrifugation), solubility, emulsion type, storage test (freeze-thaw), and measurement of droplet size and polydispersity index with a Particle Size Analyzer (PSA). The results showed that formula F1 had the most optimal characteristics, with a clarity of 80% indicating better droplet dispersion with an average droplet size of 13.96 nm and a polydispersity index of 0.216 indicating the successful formation of a stable and uniform nanoemulsion. Nanoemulsions showed good physical stability, were soluble in polar and semi-polar solvents, and were oil-in-water (O/W) type supporting increased solubility and availability of active compounds in air-based systems. These results indicate that F1 is the most potential formula to increase the bioavailability of active compounds in soursop leaves and can be further developed as a carrier system candidate in pharmaceutical preparations.
PEMBERDAYAAN MASYARAKAT DALAM PENGOLAHAN MINUMAN KESEHATAN INSTAN SEBAGAI PENINGKATAN DAYA TAHAN TUBUH DI RT 04/RW01 DESA MENDALO INDAH Riski Gusti, Diah; Marlinda, Lenny; Ekasari, Munifilia; Erliana, Dina; Rahmi, Rahmi; Pratiwi, Nurul; Nuraini, Syafira; Putri Pandulu, Clara; Yusria Putri, Desta; Fitri, Selta; Wahyuningsih, Iga
Martabe : Jurnal Pengabdian Kepada Masyarakat Vol 9, No 2 (2026): MARTABE : JURNAL PENGABDIAN KEPADA MASYARAKAT
Publisher : Universitas Muhammadiyah Tapanuli Selatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31604/jpm.v9i2.%p

Abstract

Mendalo Indah Village has great potential for trade because of its strategic location near two major universities in Jambi Province, namely Jambi University and UIN Sultan Thaha Jambi. Students in this area have a strong preference for instant food and beverages as a result of their busy academic and practicum schedules. The urgency of this community service activity lies in the need for instant but natural health supplements among students, as well as the need for housewives to gain additional income. The training on the production of “Japan Instan” in Mendalo Indah Village aims to empower the community, especially housewives and unemployed women, by developing creative economic activities through innovative and marketable prod ucts. Ginger was chosen as the main ingredient because of its well-known health benefits, such as relieving headaches, preventing colds, improving digestion and increasing appetite (stimulant). Ginger is also a commonly found local plant. The training covered the processing of ingredients, packaging and marketing strategies. Additionally, pandan leaves were utilized as an innovation to enhance the flavor and aroma, resulting in a healthy instant beverage product