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Husnarika Febriani, Husnarika
Universitas Islam Sumatera Utara
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PENGARUH PEMBERIAN EKSTRAK ETANOL BUAH AREN (Arenga pinnata Merr.) TERHADAP PROFIL DARAH TIKUS PUTIH (Rattus norvegicus L.) YANG DIINDUKSI KARBON TETRAKLORIDA (CCl4) Triyudha, Garibaldi; Febriani, Husnarika; Aisyah Hutasuhut, Melfa
Jurnal Biogenerasi Vol. 10 No. 2 (2025): Volume 10 no 2 periode februari - september 2025 ( continues)
Publisher : Universitas Cokroaminoto Palopo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30605/biogenerasi.v10i2.5636

Abstract

Carbon tetrachloride (CCl4) is a common sanitizer and decomposer that can be harmful if eaten, inhaled, or absorbed through the skin. Herbal plants can be used as therapeutic treatment to counteract the effects of these dangerous drugs. Palm fruit (Arenga pinata Merr) is one of them. The aim of this research was to determine the effect of administering palm fruit extract on the number of erythrocytes, leukocytes, hemoglobin and platelets in white rats induced by carbon tetrachloride.This study used a completely randomized design with 20 mice divided into 5 treatment groups. Negative controls were given food, drink and 1 ml/kg BW olive oil, positive controls were given 1 ml/kg BW carbon tetrachloride and olive oil with a ratio of 1:3. Treatments 1, 2 and 3 were given carbon tetrachloride 1ml/kg BW and olive oil with a ratio of 1:3 and given ethanol extract of palm fruit at different doses (P1= 90 mg/kg BB, P2= 180 mg/kg BB, P3= 360 mg/kg BB) for 15 days. The results obtained include that the ethanol extract of palm fruit has a very significant effect on erythrocytes, hemoglobin, leukocytes and platelets with a P value = 0.000 and the average value of erythrocytes (7.66 µl), hemoglobin (13.45 g/dl), leukocytes (15 .34 µl), platelets (895.25 mm²). The optimal dose of palm fruit extract to counteract and improve the number of erythrocytes, hemoglobin, leukocytes and platelets is a dose of 360 mg/kg BB.
PENGARUH PEMBERIAN EKSTRAK ETANOL BUAH AREN (Arenga pinnata Merr.) TERHADAP KADAR KREATININ, UREUM DAN HISTOLOGI GINJAL TIKUS PUTIH (Rattus norvegicus L.) YANG DIINDUKSI KARBON TETRAKLORIDA (CCl4) Awaliah Sifa, Nurharija; Febriani, Husnarika; Widiarti, Leni
Jurnal Biogenerasi Vol. 10 No. 2 (2025): Volume 10 no 2 periode februari - september 2025 ( continues)
Publisher : Universitas Cokroaminoto Palopo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30605/biogenerasi.v10i2.5637

Abstract

One substance that produces radical compounds is carbon tetrachloride (CCl4). As a solvent, insecticide, coolant, stain remover, and soap, carbon tetrachloride is widely used. Direct skin contact, ingestion, inhalation, and eye contact are ways this material enters the body. The antioxidants found in palm fruit (Arenga pinnata Merr.) can help protect against damage caused by free radicals. This study aims to determine how giving ethanol extract of palm fruit (Arenga pinnata Merr.) to white rats (Rattus norvegicus L.) affects creatinine, urea levels and kidney histology when exposed to carbon tetrachloride (CCl4).This study used a completely randomized design with 20 mice divided into 5 treatment groups. Negative controls were given food, drink and 1 ml/kg BW olive oil, positive controls were given 1 ml/kg BW carbon tetrachloride and olive oil with a ratio of 1:3. Treatments 1, 2 and 3 were given carbon tetrachloride 1ml/kg BW and olive oil with a ratio of 1:3 and given ethanol extract of palm fruit at different doses (P1= 90 mg/kg BW, P2= 180 mg/kg BW, P3= 360 mg/kg BW) for 16 days. The results obtained include that ethanol extract of palm fruit has a very significant effect on creatinine, urea and kidney histology. The optimal dose of palm fruit ethanol extract to improve kidney is a 360 mg/kg BW.
PENGARUH PAKAN TAMBAHAN TEPUNG KEPALA UDANG DAN KACANG HIJAU (Vigna radiate L.) TERHADAP KANDUNGAN PROTEIN DAN BOBOT PADA IKAN NILA (Oreochromis niloticus) (Oreochromis niloticus) Septiandi, Rigi; Febriani, Husnarika; Pima Sari Tambunan, Efrida
Jurnal Biogenerasi Vol. 10 No. 2 (2025): Volume 10 no 2 periode februari - september 2025 ( continues)
Publisher : Universitas Cokroaminoto Palopo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30605/biogenerasi.v10i2.5723

Abstract

Shrimp head flour is processed from shrimp processing waste and used as an alternative feed that has a fairly high nutritional content. While mung bean flour is processed from the main ingredient of mung beans that have been semi-processed which have a fairly high vegetable protein content. The purpose of this study was to see whether the provision of additional feed of mung bean flour (Vigna radiata L.) and shrimp head flour affects the weight and protein content of tilapia (Oreochromis niloticus). The design used in this study was a completely randomized design (CRD) with 4 treatments on 20 tilapia. P0 = 100% commercial feed, P1 = 75% commercial feed, 20% shrimp head flour, and 5% mung bean flour, P2 = 50% commercial feed, 40% shrimp head flour, 10% mung bean flour, P3 = 25% commercial feed, 60% shrimp head flour, 15% mung bean flour. This study used two parameters, namely the weight of tilapia produced and the protein content of tilapia. Data analysis using one way ANOVA and continued with Duncan's further test. The results obtained in the addition of additional feed of green bean flour and shrimp head flour had a significant effect on the protein content of tilapia with a value of 15.26 (p = 0.000). The results of green bean flour affected the growth of tilapia weight with a value of 13.6% (p = 0.000). The most optimal feed in increasing the protein content and body weight of tilapia was in group P3.
Perbandingan Model Pembelajaran Contextual Teaching and Learning (CTL) dan Model Pembelajaran Numbered Heads Together (NHT) terhadap Hasil Belajar pada Materi Sistem Pernapasan di Kelas XI SMA Negeri 2 Kota Pinang Nasution, Nur Ainun; Febriani, Husnarika; Tambunan, Efrida Pima Sari
Mimbar Kampus: Jurnal Pendidikan dan Agama Islam Vol. 23 No. 1 (2024): Mimbar Kampus: Jurnal Pendidikan dan Agama Islam
Publisher : Intitut Agama Islam Nasional Laa Roiba Bogor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47467/mk.v23i1.1868

Abstract

This research aims to determine the comparison of the Contextual Teaching and Learning (CTL) learning model with the Numbered Heads Together (NHT) learning model on learning outcomes in respiratory system material in class XI SMA Negeri 2 Kota Pinang. This research is quantitative research with a quasi-experimental type of research. With a population of all class Using samples XI IPA-1 as experimental class I and XI IPA-2 as experimental class II. The instrument in this research uses a multiple choice form of learning outcomes test. The data analysis technique uses the t test at the significance level α = 0.05. The results of posttest data hypothesis testing showed that the average score for Experimental Learning Model I (Contextual Teaching and Learning (CTL)) = 83.3 and Experiment II (Numbered Heads Together (NHT)) = 76.7. Hypothesis testing comparing the respiratory system learning outcomes of students in Experiment I and Experiment II, obtained tcount (2.47) > ttable 2.048, then Ho is rejected and Ha is accepted.
Effect Of Kenikir Leaves Extract On Gastric Histology Description Of Male White Rats Induced By Aspirin JS, Nurri Yusriyyah; Febriani, Husnarika; syukriah, Syukriah
Al-Hayat: Journal of Biology and Applied Biology Vol. 5 No. 2 (2022)
Publisher : Fakultas Sains dan Teknologi, UIN Walisongo Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21580/ah.v5i2.11592

Abstract

Using aspirin for long time make ulcer. Using traditional medicinal plants is alternative in treating gastric ulcers. This experiment aims to determine effect of kenikir leaves extract (Cosmos caudatus Kunth.) on gastric morphology and histology decription of male white rats (Rattus norvegicus) induced by aspirin. 25 rats were divided into 5 groups, KN (control), KP (aspirin 200 mg/kgBW for 10 days), P1 (aspirin 200 mg/kgBW for 10 days + kenikir leaves extract 700 mg/kgBW for 14 days). ), P2 (aspirin 200 mg/kgBW for 10 days + kenikir leaves extract 800 mg/kgBW for 14 days), P3(aspirin 200 mg/kgBW for 10 days+kenikir leaves extract 900 mg/kgBW for 14 days). Parameters observed were morphological and histological of the gastric. Data were analyzed by oneway ANOVA test and continued with Duncan's test. The results kenikir leaves did not have a significant effect on the morphology but histologically, kenikir leaves extract had a significant effect by improving the thickness of gastric layer. It can be concluded that kenikir leaves extract can be used as an alternative to treat gastric ulcers because it can improve the thickness of gastric layer. 
Pengaruh Pemberian Ekstrak Etanol Buah Gandaria (Bouea macrophylla Griff.) Terhadap Profil Lipid Tikus Putih (Rattus norvegicus L.) Yang Diinduksi Karbon Tetraklorida (CCI4) Putri, Nesya Destika; Febriani, Husnarika
Bioscientist : Jurnal Ilmiah Biologi Vol. 13 No. 3 (2025): September
Publisher : Department of Biology Education, FSTT, Mandalika University of Education, Indonesia.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33394/bioscientist.v13i3.17449

Abstract

This study aimed to evaluate the effect of ethanolic extract of gandaria fruit (Bouea macrophylla Griff.) on the lipid profile of male white rats (Rattus norvegicus L.) induced with carbon tetrachloride (CCl₄). The study highlights the potential hypolipidemic activity of the extract by measuring levels of total cholesterol, triglycerides, Low Density Lipoprotein (LDL), and High Density Lipoprotein (HDL). A Completely Randomized Design (CRD) was employed, involving 25 rats divided into five groups: negative control, positive control (CCl₄ without treatment), and three treatment groups administered the extract at doses of 100, 150, and 200 mg/kg body weight for 30 days. Data were analyzed using ANOVA followed by Duncan’s Multiple Range Test (DMRT) at a significance level of p < 0.05. The results showed that the 200 mg/kg dose significantly reduced levels of total cholesterol, triglycerides, and LDL, while the highest increase in HDL was observed at the 100 mg/kg dose. These findings also indicate that the ethanolic extract of Bouea macrophylla fruit exhibits dose-dependent hypolipidemic and antioxidant effects and has potential as a natural therapeutic candidate for improving lipid profile disorders caused by chemically induced liver damage.
Content Eligibility Analysis of Biology Textbook on The Curriculum 2013 of First Grade (Xst) Senior High School: Covered In Aspect Enviromental Literacy Syahpitri, Juliana; Febriani, Husnarika; Rohani, Rohani
JURNAL PEMBELAJARAN DAN BIOLOGI NUKLEUS Vol 8, No 3: Jurnal Pembelajaran Dan Biologi Nukleus November 2022
Publisher : Universitas Labuhanbatu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36987/jpbn.v8i3.3425

Abstract

Textbooks are the crucial factors governing learning sustainability and are also easy to find for students and teachers and learners in the learning process. An analysis of the book is an activity that is carried out to identify the completeness and harmonious content of the book's material. The purpose of this study is to analyze the level of environmental literacy in first grade (x-class) of Senior High School, biology textbook based on the environmental literacy aspect: natural history and ecology, knowledge of environmental issues and issues, cognitive socio-political knowledge, cognitive skills, factors that influence and define responsible behaviour toward the environment, and responsible behaviour toward the environment. The study analyzed three different biological textbooks by publishing. The biology textbook analysis for first grade (x-class) of Senior High School were based on the 2 chapters of environmental literacy, which are ecosystem material and environmental change materials. The study is a descriptive study with content analysis. Instruments in this study use assessment instruments with 6 indicators and 30 statements validator already validated. Based on the analysis, results from a percentage of the book I were Grafindo publisher 31.66% (enough eligible category), Intan Parawirapublisher of were 32.2% (enough eligible category), the Erlangga book showed 32.7% (enough eligible category).
Analisa Kandungan Tembaga (Cu) pada Udang Galah (Macrobrachium rosenbergii) di Sungai Asahan Tanjungbalai Pakpahan, Sonia Faras; Febriani, Husnarika; Syukriah, Syukriah
Spizaetus: Jurnal Biologi dan Pendidikan Biologi Vol 5 No 2 (2024): Spizaetus: Jurnal Biologi dan Pendidikan Biologi
Publisher : Program Studi Pendidikan Biologi, FKIP, Universitas Nusa Nipa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55241/spibio.v5i2.366

Abstract

Sungai Asahan Tanjungbalai merupakan sungai yang menghasilkan ekspor laut dan perairan seperti kerang, ikan, dan udang. Akumulasi tembaga yang berlebihan di dalam tubuh organisme dapat menganggu proses fisiologis dan metabolisme. Tujuan dari penelitian ini adalah untuk mengetahui kadar logam berat tembaga (Cu) pada air dan daging udang galah (Macrobrachium rosenbergii). Penelitian ini menggunakan penelitian observasi, penentuan lokasi pengambilan sampel menggunakan metode purposive sampling, pengujian sampel air dan daging menggunakan Sepktrofotometer Serapan Atom (SSA). Analisis data menggunakan perhitungan BCF (Bioconcentration Factor). Hasil yang didapatkan pada uji logam air yaitu: stasiun I (0,0095 mg/L), stasiun II (<0,006 mg/L) dan stasiun III (0,0012 mg/L) yang kadarnya masih dibawah baku mutu (PPRI No. 22 Tahun 2021). Hasil yang didapatkan pada uji logam pada daging udang yaitu: stasiun I (9,09 mg/L), stasiun II (11,79 mg/L) dan stasiun III (9,55 mg/L) yang kadarnyamasih di bawah baku mutu (Direktur Jendral POM No. 03725 / B / SK / VII / 89). 
Pengaruh Media Tambahan Susu Bubuk Afkir terhadap Bobot Badan dan Kandungan Nutrisi Maggot (Hermetia illucens) Lingga, Atika; Febriani, Husnarika; Tambunan, Efrida Pima Sari
Spizaetus: Jurnal Biologi dan Pendidikan Biologi Vol 5 No 2 (2024): Spizaetus: Jurnal Biologi dan Pendidikan Biologi
Publisher : Program Studi Pendidikan Biologi, FKIP, Universitas Nusa Nipa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55241/spibio.v5i2.418

Abstract

Susu bubuk afkir merupakan susu yang sudah tidak dipakai dan memenuhi syarat sebagai pakan tambahan pada ternak karena memiliki komposisi gizi yang memadai. Penelitian ini bertujuan untuk mengetahui pengaruh media tambahan susu bubuk afkir terhadap bobot badan dan kandungan nutrisi berupa protein dan lemak pada maggot (Hermetia illucens). Penelitian ini menggunakan rancangan acak lengkap dengan 20 gram larva maggot dibagi menjadi 4 kelompok perlakuan. P0= 100% limbah buah. P1= 75% limbah buah dan 25% susu bubuk afkir. P2= 50% limbah buah dan 50% susu bubuk afkir. P3= 25% limbah buah dan 75% susu bubuk afkir. Parameter yang diukur penimbangan bobot dan kandungan protein serta lemak maggot (Hermetia illucens). Analisis data menggunakan oneway ANOVA dan dilanjutkan dengan uji Duncan. Hasil yang diperoleh dalam pemberian media tambahan susu bubuk afkir berpengaruh terhadap bobot badan maggot (Hermetia illucens) dengan nilai p=0,000. Hasil yang didapatkan dalam pemberian media tambahan susu bubuk afkir berpengaruh terhadap kandungan protein dan kandungan lemak maggot (Hermetia illucens) dengan nilai p=0,000. Media yang paling optimal dalam pertumbuhan bobot badan dan kandungan nutrisi berupa protein dan lemak maggot adalah pada kelompok P2 dengan bobot sebesar (137,60±2,88b), kandungan protein sebesar (37,5640±0,58d) dan kandungan lemak sebesar (63,7020±0,21d). Penelitian ini memiliki implikasi bagi perkembangan ilmu pengetahuan dalam Pemberian media tambahan susu bubuk afkir berpengaruh nyata meningkatkan pertumbuhan bobot badan maggot (Hermetia illucens). 
Pengaruh Pemberian Ekstrak Daun Benalu Kopi (Scrulla feruginea (Jack) Danser) terhadap Kadar Ureum dan Kreatinin pada Tikus Putih Jantan (Rattus norvegicus L.) yang Diinduksi Aloksan Ariani, Liza; Febriani, Husnarika; Tambunan, Efrida Pima Sari
Spizaetus: Jurnal Biologi dan Pendidikan Biologi Vol 5 No 3 (2024): Spizaetus: Jurnal Biologi dan Pendidikan Biologi
Publisher : Program Studi Pendidikan Biologi, FKIP, Universitas Nusa Nipa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55241/spibio.v5i3.430

Abstract

Diabetes melitus merupakan suatu penyakit yang disebabkan karena pankreas tidak cukup dalam memproduksi insulin atau tubuh tidak bisa memanfaatkan insulin secara efektif. Diabetes melitus dapat diobati dengan menggunakan daun benalu kopi karena mengandung senyawa metabolit sekunder seperti flavonoid, alkaloid, tanin, steroid dan saponin. Tujuan penelitian ini untuk mengetahui pengaruh pemberian ekstrak etanol daun benalu kopi (Scrulla feruginea (Jack) Danser) terhadap kadar ureum dan kreatinin pada tikus putih jantan (Rattus norvegicus L.) yang diinduksi aloksan dan dosis ekstrak etanol daun benalu kopi (Scrulla feruginea (Jack) Danser) yang efektif menurunkan kadar ureum dan kreatinin pada tikus putih jantan (Rattus norvegicus L.) yang diinduksi aloksan. Rancangan penelitian menggunakan metode Rancangan Acak Lengkap (RAL) dengan pembagian 6 kelompok yaitu: kontrol normal, kontrol negatif, kontrol positif, P1: 200 mg/kg BB, P2: 300 mg/kg BB, P3: 400 mg/kg BB, dengan masing-masing 4 ulangan. Pengujian kandungan senyawa kimia pada daun benalu kopi dilakukan dengan skrining fitokimia, uji flavonoid total dan antioksidan. Analisis data menggunakan oneway ANOVA dan dilanjutkan dengan uji Duncan. Hasil yang didapatkan di antaranya ekstrak etanol daun benalu kopi (Scrulla ferruginea (Jack) Danser) berpengaruh nyata dalam menurunkan kadar ureum dan kreatinin pada tikus putih jantan (Rattus norvegicus L.) yang diinduksi aloksan dengan mendapatkan nilai p=0.000. Dosis ekstrak etanol daun benalu kopi (Scrulla feruginea (Jack) Danser) yang aman dan efektif untuk menurunkan kadar ureum dan kreatinin pada tikus yang diabetes adalah dosis 300 mg/kg BB. Penelitian ini memiliki implikasi bagi perkembangan ilmu pengetahuan dalam pemberian ekstrak daun benalu kopi (Scrulla feruginea (Jack) Danser) terhadap kadar ureum dan kreatinin pada tikus putih jantan (Rattus Norvegicus L.) yang diinduksi aloksan.
Co-Authors Aisyah Hutasuhut, Melfa Aldyan, M Ardhi Amira, Siti Andrian, Luthfiyah Aprilianti, Intan Ariani, Liza Astuti, Mega Yulli Awaliah Sifa, Nurharija Ayunda, Sapna Azhari, Mhd Bayu Butar-Butar, Tri Novitashari Cutami, Ledia Fristia Damanik, Novita Fadillah, Nurul Maurito Harahap, Maisaroh Harahap, Nurbaiti Hasibuan, Turlan Rumaito Hutasuhut, Melfa Aisyah JS, Nurri Yusriyyah Khairuddin - Khairuna Khairuna Leni Widiarti, Leni Lestari, Sri Murni Ayu Lingga, Atika Mashitah, Ulfa Matondang, Indah Dinamayanti Mayasari, Ulfayani Muhammad Andry Nabila, Jihan Nasution, Nur Ainun Nasution, Putri Aminah Ningrum, Nurlian Augustin Nur Faizah, Ulinnuha Nurcahyani, Nadya Nurjannah, Suci Nurjannah Pakpahan, Sonia Faras Parinduri, Ayu Nurhabibah Pima Sari Tambunan, Efrida Puspita Sari Putri, Nesya Destika Rahmadani, Nurul Rahmadina, Rahmadina Rambe, Rendi Ardiansyah Rasyidah Rasyidah Riskiyah, Ainur Rohani Rohani Sahputra, Bagus Sajaratud Dur, Sajaratud Sari, Nada Aprilia Septiandi, Rigi Simamora, Indah Anda Rini Solin, Raslina Surbakti, Nur Anisah Br Syahfitri, Fazira Rahma Syahpitri, Juliana Syahputra, Akbar Syukriah Syukriah Syukriah, Syukriah Tambunan, Efrida Pima Tambunan, Efrida Pima Sari Triyudha, Garibaldi Ulfa, Syarifah Widya Zahratul Idami