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REVIEW ARTIKEL: ANALISIS AKTIVITAS ANTIOKSIDAN GENUS Syzygium MENGGUNAKAN METODE DPPH Manahan Situmorang; Devina Chandra; Dumartina Hutauruk; Widia Sari; Aufa Azkia; Theesyah R Sianturi; Eva Diansari Marbun
Jurnal Intelek Dan Cendikiawan Nusantara Vol. 2 No. 3 (2025): JUNI-JULI 2025
Publisher : PT. Intelek Cendikiawan Nusantara

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Abstract

Genus Syzygium telah banyak diteliti karena potensinya dalam menetralkan radikal bebas yang diketahui berperan dalam perkembangan penyakit degeneratif. Penelitian ini bertujuan untuk meninjau dan membandingkan aktivitas antioksidan dari berbagai spesies Syzygium dengan metode DPPH (2,2-diphenyl-1-picrylhydrazyl). Kajian dilakukan dengan cara pendekatan deskriptif melalui telaah literatur terhadap sepuluh artikel ilmiah. Berdasarkan hasil kajian, ekstrak daun Syzygium zollingerianum menunjukkan potensi antioksidan tertinggi dengan nilai IC₅₀ sebesar 0,57 μg/mL, melampaui efektivitas vitamin C sebagai pembanding. Aktivitas tinggi juga ditunjukkan oleh ekstrak biji S. polycephalum (IC₅₀ = 5,246 ppm) dan kulit batang S. guineense (IC₅₀ = 5,62 ppm). Beberapa studi menunjukkan bahwa daun S. polyanthum memiliki aktivitas sangat kuat dengan nilai IC₅₀ antara 13–15 ppm. Aktivitas kuat juga ditemukan pada buah Lobi-lobi (IC₅₀ = 50,01 ppm) dan daging buah kupa (IC₅₀ = 58,08 ppm). Sementara itu, aktivitas sedang hingga lemah ditemukan pada daun pucuk merah (IC₅₀ = 337 ppm), daun jamblang (IC₅₀ = 162,2 ppm), dan kulit batang jamblang (IC₅₀ = 164,3 ppm), sedangkan fraksi n-heksan menunjukkan aktivitas sangat lemah (IC₅₀ = 5235,6 ppm). Variasi aktivitas ini dipengaruhi oleh bagian tanaman, jenis pelarut, dan kandungan senyawa bioaktif seperti fenolik dan flavonoid. Kesimpulannya, spesies seperti S. zollingerianum, S. polycephalum, dan S. guineense memiliki potensi tertinggi, dengan bagian daun, biji, dan kulit batang sebagai sumber antioksidan paling efektif untuk aplikasi kesehatan preventif.
Edukasi Pemanfaatan Daun Kapulaga terhadap Tambak Udang di Desa Sikhorilafau Dumartina Hutauruk; Manahan Situmorang; Suharyanisa Suharyanisa; Yanti Musyawarah
Jurnal Nusantara Berbakti Vol. 3 No. 2 (2025): April: Jurnal Nusantara Berbakti
Publisher : Universitas Kristen Indonesia Toraja

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59024/jnb.v3i2.641

Abstract

The many negative effects on the use of chemical-based medicine have made researchers increasingly interested in looking for alternative natural ingredients that have high therapeutic potential and minimal side effects. One of the plants that is often used as a medicinal ingredient is cardamom (Amomum cardamomum L.), which comes from the Zingiberaceae family. Cardamom has been widely used by the community as an aromatic, carmimental (reducing gas in the stomach), cough medicine, mouth freshener, and various other traditional medicines. The content of bioactive compounds such as alkaloids, flavonoids, tannins, and saponins in cardamom is believed to play an important role in providing pharmacological effects. This study aims to analyze the bioactivity level of toxicity of cardamom leaf ethanol extract against shrimp larvae Artemia salina L. using the Brine Shrimp Lethality Test (BSLT) method and determine the LC₅₀ value as a toxicity parameter. The research method used an experimental quantitative approach with six treatment concentrations, namely 25 ppm, 50 ppm, 100 ppm, 200 ppm, 500 ppm, and 1000 ppm, as well as one negative control. Each treatment was replicated five times to get accurate results. A total of 350 Artemia salina larvae were used, with 10 larvae for each concentration test. Larval mortality was calculated after 24 hours of treatment to determine the potential toxicity of the extract. In addition to laboratory research, community service programs are carried out to increase coastal communities' understanding of the use of cardamom leaves for pond shrimp larvae. This education is important because the results of the research are expected to be the basis for the use of natural materials that are safer, more environmentally friendly, and sustainable in the management of shrimp ponds.
TINJAUAN LITERATUR: KAJIAN EFEKTIVITAS ANTI JAMUR DAUN SIRIH HIJAU & KUNYIT DALAM PENGOBATAN KEPUTIHAN WANITA Natanael Priltius; Candrika Kumala; Manahan Situmorang; Nova Indah Bakara; Sri Indriyani Sinaga; Febrina Theresa Manurung
Berajah Journal Vol. 5 No. 12 (2026): Berajah Journal
Publisher : CV. Lafadz Jaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47353/bj.v5i12.155

Abstract

Pathological vaginal discharge is a common reproductive health problem among women, especially in Indonesia, with a prevalence reaching 75%. Conventional treatment for vaginal discharge is often constrained by cost and limited access to healthcare services, making traditional remedies such as green betel leaf decoction and turmeric extract popular alternatives. This study aimed to examine the antifungal effectiveness of green betel leaf decoction and turmeric in significantly reducing pathological vaginal discharge among adolescent to adult women over the long term. The research method employed was a literature review with a systematic search of the Google Scholar database from January 2020 to July 2024 using the keyword “Traditional Medicine for Vaginal Discharge.” From 3,010 initial articles, after screening for duplication and relevance, five articles were selected for descriptive analysis. The results showed that green betel leaf decoction and turmeric extract had high effectiveness in reducing pathological vaginal discharge, as evidenced by a significant decrease in discharge scores (p<0.05) across various age groups of women. Bioactive compounds such as essential oils, flavonoids, and curcumin provide antimicrobial, anti-inflammatory, and immunomodulatory activities that help restore vaginal microflora balance. In conclusion, green betel leaf decoction and turmeric were effective in significantly reducing pathological vaginal discharge among adolescent to adult women, in accordance with the long-term treatment objectives.
Sosialisasi Kepada Masyarakat Tentang Bijak dalam Mengkonsumsi Obat Pada Lansia di Kecamatan Tanjung Pura Kabupaten Langkat Dhea Nur Fadhilah; Manahan Situmorang; Dumartina Hutauruk; Julia Susanti
Jurnal Nusantara Berbakti Vol. 1 No. 3 (2023): Juli : Jurnal Nusantara Berbakti
Publisher : Universitas Kristen Indonesia Toraja

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59024/jnb.v1i3.201

Abstract

Elderly is an age group in humans who have entered the final stages of their life phase. The group that is categorized as elderly will experience a process called the aging process. Indonesia is entering a period of aging population, where there is an increase in life expectancy followed by an increase in the number of elderly people. In Indonesia, there has been an increase in the number of elderly people from 18 million people (7.56%) in 2010 to 25.9 million people (9.7%) in 2019, and can be expected to continue to increase where in 2035 it will be 48.2 million people (15.77%). On the other hand, an increase in the number of elderly people will be a problem if the elderly have health problems. The elderly are a group of people who are susceptible to disease and have different physiological functions from young people, so their treatment pattern becomes more careful. The purpose of this community service activity is to provide outreach and information to the public about the proper and correct use of drugs in Tanjung Pura District, Langkat Regency regarding Provision of Drug and Wise Information on the proper and correct use of drugs. The method of this activity involved the community in Tanjung Pura District, Langkat Regency, namely lectures, distribution of leaflets, and questions and answers. Lectures are presented in the form of power point presentations, distribution of leaflets in the form of brochures followed by a discussion or question and answer session about Wisdom in taking medicine in the elderly. The result of this activity is that in Tanjung Pura District, Langkat Regency understand and are wise in taking drugs, especially in the elderly.
PENGGUNAAN OBAT LUKA DENGAN MENGGUNAKAN OBAT ALAMI LIDAH BUAYA SEBAGAI ANTIBAKTERI SMP MUHAMMADIYAH 4 MEDAN Suharyanisa Suharyanisa; Jon Kenedy Marpaung; Manahan Situmorang; Dumartina Hutauruk; Anzelina Simbolon, Chindy; Elizabet Kristina Purba; ElsaNayla Sari; Jansela Rotua Malau; Muhammad Kausar; Rudolfo Zamili
Jurnal Abdimas Mutiara Vol. 7 No. 1 (2026): JURNAL ABDIMAS MUTIARA
Publisher : Universitas Sari Mutiara Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jam.v7i1.6832

Abstract

Latar belakang: Lidah buaya (Aloe vera) merupakan salah satu tanaman obat yang banyak ditemukan di lingkungan sekitar dan dikenal memiliki aktivitas antibakteri serta kemampuan mempercepat penyembuhan luka. Kandungan senyawa aktif di dalam lidah buaya berperan dalam menghambat pertumbuhan bakteri dan membantu proses regenerasi jaringan kulit. Meskipun memiliki potensi yang besar, pemanfaatan lidah buaya sebagai obat luka alami masih belum dipahami secara optimal, khususnya di kalangan pelajar. Kegiatan pengabdian kepada masyarakat ini penting dilakukan sebagai upaya edukasi untuk meningkatkan pengetahuan dan kesadaran siswa mengenai pemanfaatan bahan alami sebagai alternatif pengobatan luka. Melalui pendekatan edukasi, diharapkan siswa mampu memahami manfaat lidah buaya secara ilmiah dan menerapkannya secara tepat dalam kehidupan sehari-hari. Tujuan: Memberikan pengetahuan kepada siswa-siswi tentang manfaat lidah buaya (Aloe vera) sebagai antibakteri alami penyembuh luka, melatih siswa-siswi melakukan pembuatan obat luka dari bahan alami lidah buaya (Aloe vera), memberikan pemahaman ilmiah kepada siswa-siswi melalui pengamatan efektivitas antibakteri penyembuh luka dari lidah buaya terhadap penyembuhan luka pada hewan percobaan. Metode: Metode pengumpulan data dilakukan melalui observasi langsung, evaluasi lisan, dan dokumentasi kegiatan. Instrumen yang digunakan meliputi lembar observasi partisipasi dan pemahaman peserta, panduan pertanyaan evaluasi, serta lembar dokumentasi berupa foto dan catatan kegiatan. Hasil Setelah pelaksanaan penyuluhan, siswa menunjukkan peningkatan pengetahuan mengenai manfaat dari tanaman lidah buaya dan juga bagamaina cara menggunakan atau mengaplikasikan tanaman lidah buaya sebagai obat bahan alami terhadap luka. Kesimpulan: Kegiatan pengabdian kepada masyarakat ini berhasil meningkatkan pengetahuan dan pemahaman peserta mengenai pemanfaatan lidah buaya (Aloe vera) sebagai obat luka alami antibakteri. Implikasi kegiatan menunjukkan bahwa edukasi berbasis bahan alami lokal efektif mendukung upaya promotif dan preventif kesehatan serta berpotensi diterapkan secara berkelanjutan di lingkungan sekolah dan masyarakat.
Co-Authors Anzelina Simbolon, Chindy Aufa Azkia Candrika Kumala Cut Masyitah Thaib Devina Chandra Dhea Nur Fadhilah Dumartina Hutahuruk Dumartina Hutauruk Elizabet Kristina Purba ElsaNayla Sari Eva Diansari Marbun Febrina Theresa Manurung Jansela Rotua Malau Jon Kenedy Marpaung Julia Susanti Monica Suryani Muhammad Kausar Natanael Priltius Nova Indah Bakara Nurlaili Safitri Rudolfo Zamili Siti Nurbaya Sri Indriyani Sinaga Steven Tandiono Suharyanisa Suharyanisa Supartiningsih - - Theesyah R Sianturi Theesyah R. Sianturi Widia Sari Yanti Musyawarah