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Oral Candidiasis in Patients with Level CD4+ Below 50 Lukisari, Cane; Rahman, Kurnia Hayati; Nafi’ah, Nafi’ah; Setianingtyas, Dwi; Femilian, Afryla
Insisiva Dental Journal: Majalah Kedokteran Gigi Insisiva Vol 13, No 1 (2024): May
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/di.v13i1.20003

Abstract

Approximately 90% of individuals diagnosed with HIV/AIDS have encountered Oral Candidiasis during the progression of their disease, especially in patients with a reduced CD4+ 200 mm3. Oral Candidiasis is a prevalent opportunistic infection of the oral cavity. Reported a case of a patient with oral candidiasis in an HIV/AIDS with CD4+ below 50 and discussed the mechanism of molecular relationship decreasing count CD4+ with virulence of Candida Albicans. In this report, we present a case of a 35-year-old female who presented with oral candidiasis. The patient's CD4+ count test revealed a level below 50 and HIV test I-II-III reactive. Human immunodeficiency Virus causes a decrease in CD4+ count and leads to opportunistic oral candidiasis infection.
SCHOOL DENTAL HEALTH PROGRAM: TRAINING OF TRAINER KESEHATAN GIGI DAN MULUT PADA GURU DAN ORANG TUA SEBAGAI UPAYA MENUJU PROGRAM “ INDONESIA BEBAS KARIES 2030” Rahman, Kurnia Hayati; paramita, Ayulistya; Sucahyo, Bambang; Revianti, Syamsulina; Pinasti, Restika Anindya; Paramita, Anisa Listya; Prameswari, Noengki; Lelyna, Nora; Handayani, Budi; Widaningsih, Widaningsih; Wedarti, Yoifah Rizka; Nilawati, Nina; Harnowo, Setyo; Prabowo, Puguh Bayu; Damaiyanti, Dian Widya
MAJU : Indonesian Journal of Community Empowerment Vol. 1 No. 6 (2024): MAJU : Indonesian Journal of Community Empowerment, November 2024
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/aj2jgc13

Abstract

Oral and dental health among school-age children is often neglected, despite its importance in supporting their quality of life. A Training of Trainer (ToT) program on oral and dental health was conducted for teachers and parents at MI KH Ramly Surabaya to support the vision of Indonesia Free from Dental Caries 2030. This training included educational sessions and guidance on proper tooth-brushing habits using fluoride toothpaste. The results showed an improvement in participants' knowledge, with higher average post-test scores compared to pre-test scores. Additionally, there was a positive behavioral change among children in maintaining oral hygiene. Although statistical tests indicated insignificant results, the intervention had a practical impact on establishing healthy habits. Support from teachers, parents, and healthcare professionals is essential to reducing the prevalence of dental caries in the future. .
Oral Health Care Management in Atypical Oral and Cutaneous Bullous Pemphigoid Widowati, Kharinna; Dewanthy P, Sri; Lukisari, Cane; Nafi’ah; Setianingtyas, Dwi; Rahman, Kurnia Hayati; Libriansyah; Riyanto, Eko; Damaiyanti, Dian W; Ayuningtyas, Nurina F.
Denta Journal Kedokteran Gigi Vol 20 No 1 (2026): February
Publisher : Fakultas Kedokteran Gigi Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/denta.v20i1.4

Abstract

Background: Bullous Pemphigoid (BP) is the most common subepidermal bullous autoimmune disease, typically presenting as tense bullae. Atypical presentations of bullous pemphigoid often mimic TEN or impetigo, creating diagnostic ambiguity. Effective management of these cases requires integrated strategies to address systemic health factors and extensive oral mucosal involvement. Objective: This report highlights the Oral Health Care Management of atypical oral and cutaneous manifestations of Bullous Pemphigoid. Case: A 58-year-old woman with a history of Diabetes Mellitus and heart disease was referred with extensive bullae, erosions, and "honey-like" crusts involving over 30% of her body surface area. Her condition worsened despite two weeks of treatment with acyclovir, which was administered for suspected herpes. The presentation was highly suggestive of TEN and impetigo. Case Management: Management of the oral and perioral lesions focused on infection prevention and pain relief. Debridement was performed using sterile gauze soaked in normal saline and 0.2% chlorhexidine. This was followed by the application of Aloevera extract gel/spray. Comprehensive systemic therapy, including corticosteroids and immunosuppressants, was coordinated by a multidisciplinary team to control the autoimmune disease and its comorbidities. Conclusion: The presence of comorbidities, such as diabetes, further complicates systemic management and heightens the risk of secondary infections, requiring meticulous wound care. A multidisciplinary diagnostic algorithm, supported by supplementary examinations, is crucial for differentiating atypical BP from TEN and impetigo infection. Adequate management of associated oral and perioral manifestations is an integral component of comprehensive patient care.
Chlorine Dioxide as an Adjunctive Oral Rinse for Burning Mouth Syndrome: A Case Series Rahman, Kurnia Hayati; Lukisari, Cane; Nafiah, Nafiah; Setianingtyas, Dwi; Priambodo, Nur Tsurayya; Widowati, Kharinna; Bhawal, Ujjal K.
Denta Journal Kedokteran Gigi Vol 20 No 2 (2026): August
Publisher : Fakultas Kedokteran Gigi Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/denta.v20i2.4

Abstract

Background: Burning Mouth Syndrome (BMS) is a chronic orofacial pain disorder characterized by a persistent burning sensation of the oral mucosa in the absence of clinically observable lesions. BMS is classified into primary (idiopathic), often associated with neuropathic or psychogenic factors, and secondary forms linked to identifiable local or systemic conditions. Objective: This report describes a case of BMS with overlapping etiologies and evaluates the role of chlorine dioxide as a supportive agent in symptom management. Case: A patient with type 2 diabetes mellitus presented with a persistent burning sensation in the oral cavity without any clinical abnormalities. The condition was diagnosed as a combination of primary BMS with a psychogenic component and secondary BMS associated with diabetic neuropathy. Case Management: Management focused on symptomatic relief and improving oral mucosal comfort. Chlorine dioxide was administered as supportive therapy to enhance oral hydration and provide a soothing effect on the mucosa. The patient reported improvement in burning symptoms following its use. Discussion: BMS is a multifactorial condition requiring comprehensive evaluation of neuropathic, systemic, and psychological factors. In this case, the coexistence of psychogenic components and diabetic neuropathy highlights the complexity of diagnosis and management. Supportive therapy using chlorine dioxide may contribute to symptom alleviation through its hydrating and soothing properties, although its mechanism and efficacy remain insufficiently established. Therefore, a multidisciplinary approach is essential for the effective management of BMS, and further studies are needed to validate the clinical benefits of chlorine dioxide in BMS management.