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All Journal Jambura Journal of Health Sciences and Research JURNAL FARMASIMED (JFM) Journal of Pharmaceutical and Health Research Jurnal Pengabdian Masyarakat Tjut Nyak Dhien Journal of Pharmaceutical and Sciences.
Tambunan, Ika Julianti
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Religion Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Education Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences

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Penyuluhan Pencegahan Diabetes Melitus Dengan Memanfaatkan Tumbuhan Obat Berkhasiat Kepada Komunitas Sehat Di Stadion Teladan Medan Tambunan, Pravil Mistryanto; Tambunan, Ika Julianti; Sari, Nurmala; Siahaan, Desi Natalia; Lubis, Salmah Handayani
ABDIMASKU : Jurnal Pengabdian Masyarakat UTND Vol 2 No 2 (2023): Edisi Juli 2023 - Desember 2023
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/jpmtnd.v2i2.776

Abstract

Telah dilakukan penyuluhan kepada komunitas sehat di Stadion Teladan Medan terkait pencegahan diabetes melitus dengan mensosialisasikan manfaat penggunaan tumbuhan obat berkhasiat. Penyuluhan dilakukan secara acak dengan mendatangi individu-individu dari komunitas sehat yang sedang beristirahat selepas berolahraga di area Stadion Teladan Medan. Adapun tim yang tergabung atas para dosen dan mahasiswa menawarkan pemeriksaan kadar gula darah gratis dengan menggunakan glucometer digital. Setelah mendapatkan hasilnya, mahasiswa lalu menginterpretasikan hasilnya kepada individu yang diperiksa. Setelah itu, tim memberikan penyuluhan agar konsisten mengimplementasikan gaya hidup sehat serta menyarankan penggunaan tumbuhan obat untuk menjaga kadar gula darah di ambang normal. Evaluasi dilakukan berdasarkan ceklis pemahaman yang diberikan kepada semua individu yang diperiksa gula darahnya. Hasil evaluasi menunjukkan bahwa, setiap individu yang diperiksa pada komunitas Sehat di Stadion Teladan Medan telah memahami materi sosialisasi yang diberikan serta mampu mengolah tanaman obat berkhasiat sebagai ramuan untuk menjaga kesehatan agar bebas dari diabetes.
Penyuluhan Penggunaan Obat Antibiotika Yang Tepat Pada Ibu PKK Di Desa Sunggal Tambunan, Ika Julianti; Febriani, Yessi; Nadia, Syarifah; Margatha, Linda; Sihotang, Supran Hidayat; Putri, Nurul Maulida; Pratiwi, Nur Hanifa; Firdaus, Tya Novita
ABDIMASKU : Jurnal Pengabdian Masyarakat UTND Vol 3 No 2 (2024): Edisi Juli 2024 - Desember 2024
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/jpmtnd.v3i2.1283

Abstract

Pengobatan sendiri dengan antibiotik sering dipengaruhi oleh faktor kesehatan sosio-kultural dan terkadang terkait dengan penyerahan antibiotik tanpa resep serta praktik peresepan yang kurang baik. Masyarakat memiliki peran penting dalam mencegah dan mengendalikan penyebaran resistensi antibiotik. Tingginya penyalahgunaan antibiotik di masyarakat disebabkan oleh rendahnya pengetahuan tentang penggunaan yang tepat. Tujuan dari pengabdian ini adalah menyebarkan pemahaman kepada masyarakat mengenai penggunaan antibiotik yang benar untuk mencegah terjadinya resistensi antibiotik. Metode pengabdian ini melibatkan pendekatan deskriptif dengan menggunakan kuisioner pre-test dan post-test untuk menganalisis pemahaman masyarakat sebelum dan setelah pemaparan materi. Pengabdian ini, dihadiri 25 partisipan yang terdiri dari ketua dan anggota PKK Desa Sunggal, Dosen dan mahasiswa Fakultas Farmasi Universitas Tjut Nyak Dhien. Harapannya pengabdian ini dapat memberikan pengetahuan tentang cara yang tepat dalam menggunakan antibiotik untuk menghindari resistensi yang dapat berdampak pada Kesehatan dan perekonomian.
Exploration of Local Knowledge of Ethnomedicine and Medicinal Plants on Nias Island Dachi, Kanne; Tambunan, Ika Julianti
Jurnal FARMASIMED (JFM) Vol 7 No 2 (2025): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v7i2.2586

Abstract

Background: The use of plants in Indonesia has been carried out for generations, especially as part of traditional medicine. This traditional medicine is still a very valuable national asset and continues to be used by communities throughout Indonesia. One of them is the Nias tribal community in North Sumatra, where around 50% of them still use and care for medicinal plants which are considered more effective and economical as treatment in their own environment. Objective: The aim of this research is to find out the various types of plants used by the people of Nias, North Sumatra, how they are processed, and which parts of the plants are used for medicine. Methode: The research method used is a combination of qualitative and quantitative methods which are explained descriptively. Data collection techniques include interviews, observation and documentation. Meanwhile, data analysis techniques include data collection, data condensation, data presentation, and drawing conclusions. Result: The research results showed that there were 46 types of medicinal plants obtained from the results of a questionnaire to the community, with a total of 20 informants from 5 villages spread across Nias Regency, North Sumatra. Traditional treatments still practiced by the people of Nias include boiling, squeezing, pounding, burning and soaking. The way it is served also shows a high level of knowledge about medicinal ingredients, such as drinking, sticking or applying, compressing, bathing, eating and applying. Conclusion: The reason for using this traditional medicine is because it is considered cheaper, easier, safer and has minimal side effects.
Evaluasi Sediaan Ekstrak Etanol Daun Sawi Langit (Cyanthillium cinereum (L) H.Rob) Sebagai Formulasi Krim Alas Bedak Tambunan, Ika Julianti; Sudewi, Sudewi; Nasyabila, Aura
Journal of Pharmaceutical and Health Research Vol 6 No 1 (2025): February 2025
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47065/jharma.v6i1.6992

Abstract

Sky mustard leaf (Cyanthillium cinereum (L.) H.Rob) is a herbaceous plant that is used as a natural medicine in the community, especially in the treatment of irritation, intestinal diseases and febrile diseases. Sky mustard leaves are known to contain secondary metabolites such as flavonoids, alkaloids, saponins, tannins, phenolics and triterpenoids. Foundation cream is very popular among women as a powder base during the process of using makeup on the face but few foundation creams use natural ingredients compared to synthetic ingredients. This study aims to determine whether sky mustard leaf extract can be formulated in a foundation cream preparation that at certain doses has antioxidant activity and does not irritate facial skin. The sample used was sky mustard leaves, the research stages began, plant identification, ethanol extract preparation, phytochemical screening, selection of standard formulas, making foundation cream preparations with concentrations of 1%, 1.5%, 2%, blank physical quality assessment of preparations and antioxidant activity tests are some of the tests carried out. The results of this study indicate that the leaves of sky mustard (Cyanthillium cinereum (L.) H.Rob) The foundation cream preparation is homogeneous, stable and has an oil-in-water (M/A) emulsion type. The cream has a pH of 5.7-5.9 after cycle testing and can be applied up to 5-7 cm with an increase in moisture content of 36.86 which is included in the “moist” category, 2% preparation (F3) is the most preferred preparation, the IC50 value of the mustard leaf extract foundation cream formulation is in the “strong” category of 63.08 ppm “very strong” 47.37 ppm at a concentration of 1%, 1.5%. So it is concluded that mustard leaf extract IC50 value is in the “very strong” category of 14.75 ppm. The IC50 value of mustard leaf extract including the “very strong” category is 14.75 ppm. so it can be concluded that sky mustard leaves can be formulated as a foundation cream preparation without irritation.
Analisa Perbandingan Metode Sokletasi dan Maserasi Daun Sisik Naga (Drymoglossum piloselloides (L.) C.Presl) sebagai Penyembuh Luka Sayat Febriani, Yessi; Tambunan, Ika Julianti; Pratiwi, Nur Hanifa; Putri, Gewa Hadyaksa
Journal of Pharmaceutical and Health Research Vol 6 No 2 (2025): June 2025
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47065/jharma.v6i2.6232

Abstract

Dragon scale leaves (Pyrrosia piloselloides (L.) M. G. Price) have activity as antibacterial, antioxidant, antipyretic and as a febrifuge. In addition, dragon scale leaves also contain secondary metabolites such as flavonoids, polyphenols, saponins, tannins and steroids. the wound healing process includes abrasions, cuts, burns, stab wounds. The wound healing process has 3 phases, namely the inflammatory phase, proliferation phase, and maturation phase. The purpose of this study was to determine the effectiveness of total flvanoid by comparing the extraction of dragon scale leaves in healing cuts on boiler chickens (Gallus domesticus). The methods used are sokletation and maceration in the process of making thick extracts while in the research using experimental methods this research was carried out starting from the sample of dragon's scale leaves (Drymoglossum piloselloids) (L.) Presl), plant identification, making simplisia powder, making extracts, phytochemical screening, and determining total flavonoid levels using UV spectrophotometry and incision wound healing tests on broiler chickens (Gallus dzomesticus).The results of research on dragon scale leaf extracts using both maceration and sokletation methods in the process of making extractions on this plant have the same secondary metabolite content, namely flavonoids, saponins, tannins, steroids and glycosides, based on testing the total flavonoid content obtained of 3.875% in the sokletation method getting lower results compared to maceration, which is 4.235%. 235%, while in this wound test carried out by ANOVA and DUNCAN statistical methods in both methods get the same results that are significant, which means there is a significant difference between wound healing or the effect of the extract given. Dragon scale leaves with a percentage of 80% provide the best wound healing process, so it can be concluded that the two methods do not have much difference, it's just that when testing the total flavonoid content obtained the largest amount in the maceration method.
Pemakaian Bahan Alami Sebagai Pembasuh Tangan Tanpa Air Dalam Sediaan Hand Sanitizer Desa Bahorok Tambunan, Ika Julianti; Febriani, Yessi; Margatha, Linda; Karima, Nurul
ABDIMASKU : Jurnal Pengabdian Masyarakat UTND Vol 4 No 1 (2025): Edisi Januari 2025 - Juni 2025
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/jpmtnd.v4i1.1576

Abstract

Kegiatan pengabdian ini bertujuan untuk meningkatkan wawasan, keterampilan, dan kesadaran masyarakat dalam memanfaatkan bahan alami sebagai antiseptik alternatif melalui formulasi hand sanitizer berbahan alami dari jeruk bali dan lidah buaya. Selain itu, kegiatan ini diharapkan dapat menjadi solusi antiseptik yang lebih ramah kulit, ekonomis, dan mudah dibuat oleh masyarakat. Pengabdian ini dilaksanakan di Kecamatan Bahorok, Langkat, Sumatera Utara, pada 30 Juli 2024. Kegiatan dilakukan melalui tiga tahapan utama: (1) penyuluhan mengenai antiseptik alami oleh dosen Fakultas Farmasi dan Kesehatan Universitas Tjut Nyak Dhien, (2) demonstrasi pembuatan hand sanitizer alami, dan (3) diskusi interaktif serta sesi tanya jawab untuk mengukur pemahaman masyarakat. Hand sanitizer diformulasikan dengan merebus jeruk bali dan mencampurnya dengan gel lidah buaya untuk menghasilkan sediaan antiseptik yang lebih ramah kulit. Kegiatan ini mendapatkan respons positif dari masyarakat, ditunjukkan dengan tingginya antusiasme peserta dalam mengikuti diskusi dan praktik pembuatan hand sanitizer. Masyarakat memahami manfaat antiseptik alami dan mampu membuat sendiri formulasi hand sanitizer dari bahan yang tersedia di lingkungan sekitar. Produk yang dihasilkan memiliki tekstur yang baik dan tidak menyebabkan kulit kering seperti produk berbasis alkohol. Kegiatan ini berhasil mencapai tujuan dengan meningkatkan pemahaman dan keterampilan masyarakat dalam pembuatan hand sanitizer berbahan alami sebagai alternatif antiseptik yang lebih aman dan ekonomis. Formulasi ini dapat menjadi solusi jangka panjang bagi masyarakat untuk menjaga kebersihan tangan dalam kondisi di mana air bersih tidak tersedia. Pemantauan lebih lanjut diperlukan untuk mengoptimalkan efektivitas dan keberlanjutan penggunaan hand sanitizer alami di masyarakat.
EFEKTIVITAS EKSTRAK DAUN BINAHONG SEBAGAI ANTIBAKTERI DALAM HAND SANITIZER Ginting, Ernawaty; Tambunan, Ika Julianti; Dachi, Kanne; Putri, Nurul Maulida; Pratama, Danawan Heru; Gori, Iradat Novtworian; Hasibuan, Munawwaroh
Jambura Journal of Health Sciences and Research Vol 7, No 1 (2025): JANUARI: JAMBURA JOURNAL OF HEALTH SCIENCES AND RESEARCH
Publisher : Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35971/jjhsr.v7i1.28704

Abstract

Hand sanitizer adalah alat yang sangat baik untuk menghilangkan bakteri di tangan yang dapat menyebabkan penyakit seperti Staphylococcus aureus dan Escherichia coli.  Dengan mengekstraknya daun binahong yang mengandung zat antibakteri flavanoid dan tanin dapat digunakan untuk membuat semprotan pembersih tangan alami. Kebaruan penelitian ini untuk mengetahui efektivitas ekstrak daun binahong sebagai antibakteri dalam Hand Sanitizer. Penelitian ini bertujuan untuk mengevaluasi efektivitas ekstrak daun binahong dalam hand sanitizer sebagai antibakteri dengan menggunakan etanol p.a. Sebagai langkah-langkahnya, dilakukan ekstraksi dan skrining daun binahong, pemilihan formula dasar, formulasi, uji antibakteri, dan evaluasi hand sanitizer. Hasil penelitian menunjukkan bahwa sediaan hand sanitizer daun sirih merah paling disukai formula F3. Hasil uji aktivitas zona hambat menunjukkan bahwa formula F3 memiliki daya hambat paling besar yaitu 18,75 mm terhadap bakteri Escherichia coli. Sebagai perbandingan, formula F1 memiliki daya hambat terbesar yaitu 15,73 mm terhadap bakteri Staphylococcus aureus. Semua pengujian pada sediaan Hand sanitizer memenuhi persyaratan berdasarkan SNI, yang berarti pengujian antibakteri dapat dikatakan “aktif”. Kesimpulannya bahwa ekstrak daun binahong efektif sebagai antibakteri dan dapat digunakan pada hand sanitizer.
Uji aktivitas antioksidan ekstrak etanol dan sari kulit nanas (Ananas comosus (L) Merr) menggunakan metode radical scavenger Nadia, Syarifah; Julianty, Siti Muliani; Tambunan, Ika Julianti; Fujiko, Muflihah
Journal of Pharmaceutical and Sciences Suppl. 1, No. 1 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i5-si.455

Abstract

Inheritance, Indonesian society has been utilizing various plants as traditional medicine for preventive measures and treatment of various diseases. The pineapple plant or (Ananas comosus (L) Merr) is one of the plants that is often used for treatment. Pineapple (Ananas comosus (L) Merr) contains flavonoids and phenolics, which are productive as natural antioxidants. This research was carried out using experimental methods. The research included collecting materials followed by plant identification, phytochemical screening, making ethanol extract from pineapple peel, and testing antioxidant activity using the radical scavenger method using a Visible Spectrophotometer. The results of research on pineapple rind Simplicia (Ananas comosus (L) Merr), ethanol extract, and water juice of nans rind contain chemical compounds of alkaloids, flavonoids, tannins, saponins, steroids/triterpenoids and glycosides. Ethanol extract and water juice from pineapple peel have antioxidant activity, which was tested using the radical scavenger method against DPPH (1,1-diphenyl-2-picryhydrazyn) solution. Ethanol extract and water juice from pineapple peel have antioxidant activity, but unlike vitamin C, the antioxidant is categorized as very strong. Meanwhile, the ethanol extract of pineapple peel is categorized as strong, and the water extract of pineapple peel is categorized as medium.
Antibacterial and Antifungal Activity Test of N-Hexane, Ethyl Acetate, and Ethanol Extracts of Menteng Leaves (Baccaurea racemosa (Reinw.) Mull.Arg.) Against Candida albicans, Staphylococcus aureus, and Escherichia coli Tambunan, Ika Julianti; Yessi Febriani; Yufida Laia; Peronika Tampubolon; Sudewi
Jurnal FARMASIMED (JFM) Vol 8 No 1 (2025): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/d6fm3g18

Abstract

Background: Infectious diseases caused by Staphylococcus aureus, Escherichia coli, and Candida albicans remain a global health problem. Since prolonged use of synthetic drugs can cause side effects and resistance, natural alternatives are needed. Menteng leaves (Baccaurea racemosa) contain alkaloids, flavonoids, saponins, steroids/terpenoids, and tannins, which have potential antimicrobial properties. Objective: This study aimed to determine the antibacterial and antifungal activities of n-hexane, ethyl acetate, and ethanol extracts of menteng leaves against S. aureus, E. coli, and C. albicans. Method: The research was conducted experimentally through sample collection, simplicia preparation, successive maceration extraction, phytochemical screening, and antimicrobial testing using the agar well diffusion method. Results: From 500 g of simplicia, 10.5 g of n-hexane extract, 11.4 g of ethyl acetate extract, and 18 g of ethanol extract were obtained. Phytochemical screening showed that all three extracts contained different secondary metabolites, with the ethanol extract having the most complete profile. The highest antimicrobial activity was observed in the ethanol extract, with inhibition zones of 18.92 mm against S. aureus, 18.35 mm against E. coli, and 19.58 mm against C. albicans at a concentration of 200 mg/mL. Conclusion: These results indicate that the ethanol extract of menteng leaves has strong potential as a natural antibacterial and antifungal agent.
Potensi Antibakteri Ekstrak Etanol Batang Balakka (Phyllanthus emblica L.) terhadap Staphylococcus epidermidis serta Evaluasi Mutu Fisik Krim Nasuha, Nabila; Saputri, Muharni; Tambunan, Ika Julianti; Julianty, Siti Muliani; Br Sitepu, Ulva Wirdana; Syahputri, Nabila; Sinaga, Manuella; Syahputri, Devi Yanti
Journal of Pharmaceutical and Health Research Vol 6 No 3 (2025): October 2025
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47065/jharma.v6i3.8525

Abstract

Balakka (Phyllanthus emblica L) is a wild plant, commonly used as a cooking spice called holat. The stem of balakka is believed to contain alkaloids, flavonoids, and tannins that have antibacterial properties. Most previous studies have focused on the fruit and leaves of balakka. On the other hand, Staphylococcus epidermidis bacteria are normal flora on human skin that cause infections. The increasing resistance of these bacteria to antibiotics makes it important to find alternative natural antibacterial agents. The purpose of this study was to examine the antibacterial activity of balakka stem extract and cream against Staphylococcus epidermidis bacteria and to evaluate the physical quality of the cream. This study used experimental methodology. The maceration method used ethanol p.a. on 100 g of balakka stem simplisia. The stages included phytochemical screening, cream formulation with concentrations of 1%, 2%, and 3%, and physical quality tests (organoleptic, homogeneity, emulsion type, pH, viscosity, stability, and irritation). Antibacterial tests were carried out using the agar well diffusion method on extracts and cream preparations. The results showed that 19.30 g of thick extract was obtained, which was positive for alkaloids, flavonoids, and tannins. The resulting cream met physical quality standards, was homogeneous, had an oil-in-water (O/W) emulsion type, a pH of 5.3–6.2, was stable, and did not cause irritation. The antibacterial activity of the extract showed inhibition zones of 14.5 mm (100 mg/ml), 11.5 mm (75 mg/ml), and 8.5 mm (50 mg/ml), while the cream showed 5.5 mm (1%), 7.5 mm (2%), and 9.5 mm (3%). Thus, ethanol extract of balakka stems has potential as an antibacterial agent and can be formulated into a safe cream that meets physical quality standards.
Co-Authors Br Sitepu, Ulva Wirdana Dachi, Kanne Febriani, Yessi Firdaus, Tya Novita Fujiko, Muflihah Ginting, Ernawaty Gori, Iradat Novtworian Hasibuan, Munawwaroh Julianty, Siti Muliani Karima, Nurul Lubis, Salmah Handayani Margatha, Linda Nabila Syahputri, Nabila Nadia, Syarifah Nasuha, Nabila Nasyabila, Aura Nurmala Sari Peronika Tampubolon Pratama, Danawan Heru Pratiwi, Nur Hanifa Putri, Gewa Hadyaksa Putri, Nurul Maulida Saputri, Muharni Siahaan, Desi Natalia Sihotang, Supran Hidayat Sinaga, Manuella Sudewi Sudewi Sudewi Syahputri, Devi Yanti Tambunan, Pravil Mistryanto Yessi Febriani Yufida Laia