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All Journal Pharmacon JPSCR : Journal of Pharmaceutical Science and Clinical Research JOURNAL LA MEDIHEALTICO Abdi Geomedisains Prosiding University Research Colloquium Prosiding Seminar Nasional Pengabdian Masyarakat Journal of Pharmaceutical and Sciences. InSTEM Usadha Journal of Pharmacy Medical Sains : Jurnal Ilmiah Kefarmasian Journal of Nutraceuticals and Herbal Medicine Jurnal Bioteknologi & Biosains Indonesia (JBBI) Jurnal Bioteknologi & Biosains Indonesia Jurnal Pengabdian Masyarakat Inovasi Indonesia
Muhammad Haqqi Hidayatullah
Universitas Muhammadiyah Surakarta
Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Nursing Physics Public Health Social Sciences Veterinary Other

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The Usage of Information System for Documenting Number of Users of Research Laboratory at Faculty of Pharmacy, Universitas Muhammadiyah Surakarta: Pemanfaatan Sistem Informasi dalam Dokumentasi Jumlah Pengguna Laboratorium Penelitian di Fakultas Farmasi Universitas Muhammadiyah Surakarta Hidayatullah, Muhammad Haqqi; Santoso, Broto; Wathony, Al; Riyanto, R
Prosiding University Research Colloquium Proceeding of The 18th University Research Colloquium 2023: Bidang Teknik dan Rekayasa
Publisher : Konsorsium Lembaga Penelitian dan Pengabdian kepada Masyarakat Perguruan Tinggi Muhammadiyah 'Aisyiyah (PTMA) Koordinator Wilayah Jawa Tengah - DIY

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Laboratories are important infrastructure for learning and research in academic sector, especially in the field of science, such as the Faculty of Pharmacy, Muhammadiyah University of Surakarta. In fact, laboratory utility records are obtained manually by writing them in a laboratory activity logbook. The time required was not efficient and did not visualize real time data are obstacles to create a recapitulation of users data per time. The system has been built by utilizing the features in Google Forms and Google Sheets. Laboratory users has been asked to fill in the required data for the main database. Furthermore, users are instructed to make a presence using Google Forms when entering and leaving the laboratory. The data can be processed and analyzed according to laboratory needs. There were 50 data users who have registered to use the research laboratory. The result is that the system has been running properly for documenting laboratory user occupancy. The system can still be upgraded if necessary. The limitations of this system are the system still needs to be improved continuously, there is no system management level, and data processing automation needs to be adjusted manually at the beginning.
EXTRACT AND FRACTIONS EXPLORATION OF DAYAK ONION (Eleutherine America-na Merr.) WITH ANTIOXIDANTS POTENTIAL USING GC-MS and FTIR METHODS Elisa, Novi; Advistasari, Yustisia Dian; Lepangkari, Jaka Seprianto; Hidayatullah, Muhammad Haqqi
Jurnal Bioteknologi & Biosains Indonesia (JBBI) Vol. 12 No. 1 (2025)
Publisher : BRIN - Badan Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55981/jbbi.2025.9209

Abstract

Free radicals can cause various diseases in the body if not treated immediately. Large levels of free radicals may trigger damage to normally functioning tissues, lipid layers, blood vessels, DNA synthesis disturbances, and even destruction of cells. The objective is to evaluate the antioxidants potential of dayak onion extract and fractions. FTIR spectrophotometers, gas chromatography-mass spectrometry (GC-MS) and an antioxidants multimode reader are some of the research methods. The outcomes of this research are identifying plants that showed the dayak onion extract of the species Eleutherine Americana Merr. It contains compounds such as flavonoids, alkaloids, tannins, and saponins. In addition, the components found in the extract, water fraction, ethyl acetate fraction, and n-hexane fraction are octadecanoic acid 298 m/z, 9-octadecanoic acid 282 m/z, undecanoic acid 214 m/z, hexadecanoic acid 368 m/z, and nonadecanoic acid 326 m/z. Therefore, the antioxidants test using the DPPH method showed that the best IC50 value is for ethyl acetate with IC50 20.56 ppm.
Pelatihan Pembuatan Sabun Buah Pepaya guna Meningkatkan Pencegahan Penyebaran Virus COVID-19 Hidayatullah, Muhammad Haqqi; Fauzi, Ahmad; Prasetyawati, Sandra Dewi; Susantiningtyastuti, Aldila
Jurnal Pengabdian Masyarakat Inovasi Indonesia Vol 2 No 2 (2024): JPMII - April 2024
Publisher : CV Firmos

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54082/jpmii.384

Abstract

Salah satu upaya mencegah penyebaran virus COVID-19 yang dapat dilakukan adalah mencuci tangan dengan sabun. Pemanfaatan sabun dapat dikombinasikan dengan berbagai zat atau tambahan yang bersifat alamiah. Zat alamiah secara umum memiliki aktivitas sebagai antimikroorganisme baik sebagai anti bakteri maupun anti virus. Salah satu bahan alam yang memiliki aktivitas anti mikroorganisme adalah buah Pepaya. Pepaya merupakan buah yang memiliki banyak manfaat baik sebagai meningkatkan kualitas kesehatan ibu hamil, menambah nafsu makan, antioksidan, tabir surya dan antibakteri dan dan antiviral. Pepaya memiliki kandungan berbagai komponen yang memiliki manfaat sebagai anti mikroorganisme dan bisa juga untuk pencegahan penyebaran COVID-19. Kegiatan pengabdian pada tanggal pada tanggal 10 Desember 2022 di dusun Salaman, Kecamatan Tulung, Kabupaten Klaten. Pengabdian ini bertujuan menunjukkan pentingnya penggunaan sabun pada masa pandemi dan pelatihan pembuatan sabun cuci tangan dengan campuran pepaya. Kegiatan tersebut diikuti oleh 17 orang ibu Dusun Salaman.
Analisis Kualitatif Kandungan Formalin pada Tahu Putih di Pasar Tradisional Surakarta Prasetyo, Berliani Ndaru; Hidayatullah, Muhammad Haqqi
Journal of Pharmaceutical and Sciences JPS Volume 9 Nomor 1 (2026)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v9i1.1278

Abstract

Background: Formalin is still frequently misused as a preservative in white tofu despite being prohibited in food products due to its toxic, irritant, and carcinogenic properties. Therefore, monitoring its presence in traditional markets requires detection methods that are simple, accurate, and well validated. Objective: This study aimed to detect formalin in white tofu sold in traditional markets in Surakarta City and to compare and validate three qualitative formalin detection methods (Nash reagent, KMnO₄, and Schiff reagent) in combination with Thin Layer Chromatography (TLC). Methods: A total of 10 white tofu samples were randomly collected from five traditional markets in Surakarta. The samples were extracted and analyzed using colorimetric tests with Nash, KMnO₄, and Schiff reagents, followed by confirmatory analysis using TLC. Method validation included determination of the limit of detection (LOD) and specificity. Results: Formalin was detected in 30% of the samples (B1, C1, and D2) by all applied methods, while the remaining 70% showed negative results. The LOD test indicated that the Nash reagent exhibited the highest sensitivity, detecting formalin at concentrations as low as 3.125 ppm, followed by TLC (6.25 ppm), Schiff reagent (25 ppm), and KMnO₄ (50 ppm). All methods demonstrated good specificity, with no false-positive results observed in blank samples and negative controls. Conclusion: This study confirms the misuse of formalin in 30% of white tofu samples from traditional markets in Surakarta. The Nash reagent is recommended as the most sensitive method for initial screening, while TLC serves as an effective confirmatory method. The combination of Nash reagent and TLC provides a simple, sensitive, and specific approach for formalin surveillance in white tofu at the field level.
Analisis Kadar Kurkumin Pada Jamu Kunyit Asam Dengan Metode Spektrofotometri Visibel Ayunita, Fidiya; Hidayatullah, Muhammad Haqqi
Journal of Pharmaceutical and Sciences JPS Volume 9 Nomor 1 (2026)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v9i1.1279

Abstract

The rhizome of turmeric (Curcuma longa L.) contains curcumin as the principal bioactive compound responsible for its diverse pharmacological activities. Therefore, the analysis of curcumin content is essential for the quality control of herbal medicines. This study aimed to determine the curcumin content in five turmeric herbal medicine samples obtained from herbal vendors in the Kartasura area. Thin-layer chromatography (TLC) was employed for qualitative identification, while visible spectrophotometry was used for quantitative analysis. Samples were selected using purposive sampling and extracted with chloroform, followed by evaporation using a water bath and reconstitution in 96% ethanol. Quantitative analysis was performed by measuring curcumin content on days 1, 2, and 3 of storage to evaluate content stability. Qualitative TLC analysis was conducted using silica gel 60 F254 as the stationary phase and a mobile phase consisting of ethanol, glacial acetic acid, and chloroform (94:5:1, v/v/v). The TLC results confirmed the presence of three curcuminoid compounds curcumin, demethoxycurcumin, and bisdemethoxycurcumin with consistent Rf values observed under UV light at 254 nm and 366 nm. Quantitative analysis using visible spectrophotometry showed significant differences in curcumin content among samples (p < 0.001) based on one-way ANOVA. Method validation demonstrated excellent linearity (R² = 0.9995), acceptable accuracy (mean recovery of 109.67%), good precision (RSD of 1.80%), and sensitivity with LOD and LOQ values of 0.128 ppm and 0.388 ppm, respectively. These findings indicate that the validated spectrophotometric method is suitable for determining curcumin content in turmeric-based herbal medicines. Variations in curcumin levels among samples may be attributed to differences in raw material quality and manufacturing processes.
UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL 70% DAN ETIL ASETAT DAUN KERSEN TERHADAP Pseudomonas aureuginosa DAN Staphylococcus aureus Azizah, Putri Salma; Hidayatullah, Muhammad Haqqi
Usadha Journal of Pharmacy Vol. 4 No. 4 (2025): November
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/ujp.v5i1.781

Abstract

Infeksi merupakan salah satu permasalahan kesehatan di masyarakat yang masih belum bisa diatasi dengan tuntas. Infeksi dapat disebabkan oleh beberapa bakteri salah satunya yaitu Staphylococcus aureus dan Pseudomonas aeruginosa. Tujuan penelitian ini yaitu untuk mengetahui perbandingan efektivitas ekstrak etanol 70% dan etil asetat daun kersen (Muntingia calabura L) dalam menghambat aktivitas bakteri dan juga untuk mengetahui kandungan golongan senyawa dalam ekstrak etanol dan etil asetat daun kersen (Muntingia calabura L) yang memiliki sifat sebagai antibakteri. Ekstrak didapatkan dari hasil maserasi dengan menggunakan pelarut etanol 70% etil asetat. Metode yang digunakan untuk mengetahui aktivitas antibakteri yaitu menggunakan metode sumuran (well diffusion) dengan menggunakan konsentrasi 80%, 40%, dan 20%, disk antibiotik ciprofloxacin sebagai kontrol positif dan DMSO sebagai kontrol negatif. Hasil uji aktivitas dianalisis dengan menggunakan uji One way anova kemudian dilanjutkan dengan uji Duncan. Hasil uji aktivitas antibakteri ekstrak etanol 70% daun kersen (Muntingia calabura L) memiliki aktivitas antibakteri yang lebih tinggi dibandingkan dengan ekstrak etil asetat terhadap bakteri Staphylococcus aureus dibandingkan dengan bakteri Pseudomonas aeruginosa. Hasil uji fitokimia ekstrak etanol 70% dan etil asetat daun kersen positif mengandung senyawa kimia flavonoid, tannin, triterpenoid, polifenol, dan saponin.
Health Education and Applying Appropriate Technology for Instant Ginger Milk in PKK Gonggangan Fauzi, Ahmad; Saifudin, Azis; Hidayatullah, Muhammad Haqqi; Amanda, Pramaisshela Rizvya
Jurnal Inovasi Sains dan Teknologi Untuk Masyarakat Vol. 4 No. 1 (2026): Mei
Publisher : Faculty of Mathematics and Natural Sciences, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/instem.v4i1.60004

Abstract

Inappropriate use of household medicine poses risks of side effects, adverse interactions, and hazards due to improper storage and disposal. This education activity was conducted to increase public knowledge and awareness regarding the DAGUSIBU (Get, Use, Save, Dispose) concept among members of the PKK group in Gonggangan Hamlet, Bolon, Colomadu, Karanganyar, Central Java. The materials provided included how to obtain medicine from official facilities such as pharmacies, usage according to dosage and indication, correct storage to maintain stability, and safe and responsible disposal of expired medicine . The delivery method consisted of interactive presentations and discussions, followed by training on the application of appropriate technology for producing instant ginger milk made from fresh ginger, lemongrass, cloves, cinnamon, cardamom, sugar, and fresh cow's milk. This training aimed to enhance skills based on local potential while opening opportunities for small and medium enterprises. Evaluation using pre-post tests showed an increase in average knowledge scores from 62.5 to 87.3 (+ 39.68%), with 90.6% of participants stating they would apply this knowledge in their daily lives. Some participants also expressed interest in developing the production of instant ginger milk for family consumption and local sales. The results indicated that DAGUSIBU education is effective in increasing awareness of proper medicine use, while appropriate technology-based training triggers entrepreneurial motivation. The combination of these two activities is expected to encourage independence in maintaining family health while improving the economic welfare of their households.
Optimasi Metode Ekstraksi Albumin Dari Ikan Gabus (Channa striata) Hidayatullah, Muhammad Haqqi; Munawwarah, Munawwarah; Suhendi, Andi
JPSCR: Journal of Pharmaceutical Science and Clinical Research Vol 8, No 3 (2023)
Publisher : Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/jpscr.v8i3.66952

Abstract

Ikan gabus (Channa striata) memiliki kadar protein yang tinggi dengan kandungan utamanya adalah albumin. Sehingga diperlukan metode dan kondisi ekstraksi yang sesuai agar mendapatkan rendemen dan kandungan albumin yang optimal. Penelitian ini bertujuan untuk mendapatkan metode ekstrkasi yang optimal antara perebusan biasa, microwave-assisted extraction (MAE) dan ultrasonic-assisted extraction (UAE) dengan parameter kadar albumin. Ekstraksi dilakukan dengan perbandingan daging ikan gabus dan akuades (1 : 1). Variasi waktu ekstraksi yaitu 5, 10 dan 15 menit. Kadar albumin ditetapkan dengan metode Lowry. Rendemen ekstrak yang dihasilkan dari 3 metode ekstraksi pada waktu ekstraksi 5 menit berurutan 2,419; 1,293 dan 1,575 %b/b. Kurva baku Albumin didapatkan persamaan regresi linier yaitu y = 3,38x + 0,7396 dengan nilai r = 0,997. Kadar albumin yang diperoleh dari 3 metode ekstraksi pada waktu ekstraksi 10 menit secara berurutan adalah 47,009 + 1,046; 44,792 + 5,372 dan 28,946 + 2,260 %b/b. Berdasarkan data tersebut, metode ekstraksi yang memberikan kadar albumin yang terbesar adalah metode perebusan dengan waktu 10 menit.
Co-Authors AA Sudharmawan, AA Advistasari, Yustisia Dian Ahsaninnisa, Azizah Amanda, Pramaisshela Rizvya Andi Suhendi Ayunita, Fidiya Azis Saifudin Azizah, Putri Salma Benny Permana Broto Santoso Elisa, Novi Fahmi, Muhammad Zaini Fauzi Ahmad Muda Hidayah, Ariesta Adriena Putri Jaka Seprianto Lepangkari Kholifatul Hakimah, Wafiq Lepangkari, Jaka Seprianto Mufidah Maulina, Fariha Muhtadi Munawwarah Munawwarah, Munawwarah Nindyasari, Asyifa Palupi, Ajeng Sekar Prasetyawati, Sandra Dewi Prasetyo, Berliani Ndaru Rachmawati, Fiony Diva Ramadhan, Muhammad Reza Riyanto, R Slamet Ibrahim Susantiningtyastuti, Aldila Wathony, Al Zafarani Azzuhra, Alifia