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PURIFYING TURBID WATER BY MORINGA SEEDS AND SAND FILTER METHODE AT NORTH HUIDU VILLAGE, GORONTALO DISTRICT, INDONESIA Zulfiayu Sapiun
International Interdisciplinary Conference on Sustainable Development Goals Vol 2 No 1 (2019): Proceedings of International Interdisciplinary Conference on Sustainable Developm
Publisher : LP2M Universitas Bina Mandiri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (545.608 KB)

Abstract

Water is a essensial for live. Water for consumption purpose needs to be treated to meet the quality guidelines of 5 Nephelometric Turbidity Unit (NTU) according to World Health Organization. There was some treatment like the use of chemical water treatment agents, which are mostly imported and are usually very expensive, and toxic. The community of North Huidu have a serious problem with turbid water. The community service team of Health Polytechnic of Gorontalo want to solve this problem. Team introduce moringa seed and sand filter as purifier water. As an underutilized tree in Gorontalo Province, Moringa oleifera (drumsticks) seeds can be used as a coagulant agent that can purify turbid water. The community service was held at 21 November 2018 at Village Office of North Huidu and attended by 50 people. After the average of pretest was 73 and the average of post test was 82. It means there was a significant enhancement of knowledge about purifying water. Moringa seeds and sand filter can be used as effective purifier at North Huidu Village.
DESIGN THE S-VVM (SOFTWARE VACCINE VIAL MONITOR) APPLICATION AS A TECHNOLOGY INNOVATION FOR VACCINE QUALITY ASSURANCE Rindi Elpianasari; Muhammad Ikhsan Umar; Mein Munriyati Tunggali; Nur Fadilla Oktaviani Kadir; Zulfiayu Sapiun
Jambura Journal of Health Sciences and Research Vol 5, No 1 (2023): JANUARI: JAMBURA JOURNAL OF HEALTH SCIENCES AND RESEARCH
Publisher : Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35971/jjhsr.v5i1.16732

Abstract

Covid-19 adalah penyakit yang disebabkan oleh virus Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-Cov-2). Munculnya pandemi ini memberikan perhatian khusus terhadap penjagaan kelayakan mutu dari suatu vaksin. Untuk penyimpanan suatu vaksin diperlukan peralatan rantai dingin vaksin (Cold chain) untuk suhu vaksin tetap dikondisi suhu yang ideal. Vaksin vial monitor (VVM) adalah sebuah etiket atau label bergambar yang dilekatkan pada botol vaksin sebagai pemantau kelayakan mutu vaksin. Namun, masih ditemukan kesalahan dan keraguan tenaga kesehatan dalam membaca VVM. Kebaruan penelitian ini karena meneliti tentang aplikasi S-VVM (Software Vaccine Vial Monitor) sebagai inovasi teknologi pemastian mutu vaksin. Penelitian ini bertujuan untuk meningkatkan keakuratan dalam monitoring kelayakan suatu vaksin dan membuat inovasi bangun ruang aplikasi yang dapat mengurangi kesalahan tenaga kesehatan dalam monitoring kelayakan mutu vaksin secara otomatis, efisien dan dapat digunakan dalam kondisi apapun dan kapanpun. Metode penelitian berupa konsep, desain, asembly, dan testing. Aplikasi ini dirancang secara sistematik dalam program software Android/iOS.  Rancangan menggunakan metode pencocokan label, yaitu backend menggunakan phyton. Pengujian pada sampel dengan cara memindai menggunakan kamera android/iOS untuk melihat perbandingan gambar pada vaksin yang akan mengidentifikasi apakah vaksin tersebut aman digunakan atau sudah tidak layak digunakan. Hasil peneltiian adalah telah terciptanya rancangan aplikasi S-VVM yang telah melalui proses evaluasi yang rigid dengan melakukan pengujian langsung yang dilakukan oleh tenaga kesehatan. Kesimpulan aplikasi dapat menguji kelaikan vaksin dengan metodi pencocokan label.Kata Kunci: Rantai dingin; S-VVM; Vaksin; Phyton, Pencocokan label AbstractCovid-19 is a disease caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-Cov-2) virus. The emergence of this pandemic pays special attention to maintaining the quality feasibility of a vaccine. For storage of a vaccine, cold chain equipment is needed for the vaccine temperature to remain at the ideal temperature condition. A vaccine vial monitor (VVM) is an illustrated etiquette or label attached to a vial to monitor vaccine quality eligibility. However, health workers still need help with reading VVM. The novelty of this research is that it examines the application of S-VVM (Software Vaccine Vial Monitor) as an innovation in vaccine quality assurance technology. This study aims to improve accuracy in monitoring the feasibility of a vaccine and make innovations in building an application space that can reduce the error of health workers in monitoring the feasibility of vaccine quality automatically and efficiently and can be used in any condition and at any time. Research methods are in the form of concepts, designs, assembly, and testing. This application is a systematic design in Android/iOS software programs. The design uses the label-matching method. That is, the backend uses python. The result of the research is that the design of the S-VVM application has been created, which has undergone a rigid evaluation process by conducting direct testing by health workers. It tests the sample by scanning using an android/iOS camera to see a comparison of images on the vaccine that will identify whether the vaccine is safe or no longer suitable for use. The app's conclusion can test the vaccine's airworthiness with a label-matching method.Keywords: Cold chain; S-VVM; Vaccine; Python, Label matching.
Edukasi Tentang Vaksin Covid-19 Pada Masyarakat Desa Buata, Bone Bolango, Provinsi Gorontalo Teti Sutriyati Tuloli; Robert Tungadi; Ariani Hutuba; Zulfiayu Sapiun
Jurnal Pengabdian Masyarakat Farmasi : Pharmacare Society Vol 1, No 2 (2022): Vol 1 Edisi 2 2022
Publisher : State University of Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (515.114 KB) | DOI: 10.3731/phar.soc.v1i2.16814

Abstract

The World Health Organization (WHO) has declared COVID-19 as a Global Pandemic so must be handled in accordance with the legislation. Vaccination is the most effective and efficient public health effort in preventing some dangerous infectious diseases. Even though, it is undeniable that there are still many community groups who refuse vaccination due to a lack of public knowledge regarding the Covid-19 vaccine. This community service Program aims to increase public knowledge about Covid-19 through education with leaflets and and direct socialization to the Buata village community, Botupinge District, Bone Bolango Regency. The results of the Service Implementation show that the Buata village community is very interested in the information conveyed about Covid-19. This is indicated by the presence of various questions about what is the definition of a vaccine, what are the types of Covid-19 vaccines, and what are the side effects of the Covid-19 vaccine. This question has been answered properly and clearly so that the community feels satisfied and very enthusiastic during the implementation of community service programme.
SUPLEMENTASI SARI DAUN KELOR (Moringa oleifera L.) MENURUNKAN BILANGAN PEROKSIDA DAN ASAM LEMAK BEBAS VCO Nangsih Sulastri Slamet; Ghaitsa Zahira Sopha Yusuf; Fadli Husain; Fihrina Mohamad; Prisca Safriani Wicita; Zulfiayu; Fitriah Ayu Maghfirah Yunus
JURNAL KATALISATOR Vol. 8 No. 1 (2023): Jurnal Katalisator Volume 8 No. 1, April 2023
Publisher : LLDIKTI X Sumbar, Riau, Jambi, Kepri

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (197.741 KB) | DOI: 10.62769/katalisator.v8i1.1698

Abstract

Syarat VCO menurut SNI 7381:2008 yaitu memiliki nilai bilangan peroksida dan kadar asam lemak bebas yang rendah. Permasalahan VCO yang beredar saat ini yaitu pada parameter organoleptik khususnya pada aroma bau tengik yang mempengaruhi kualitas dan penyimpanan. Sehingga untuk mengatasi hal tersebut diperlukan antioksidan alami. Daun kelor merupakan tanaman yang berpotensi sebagai antioksidan alami, sehingga berpotensi dalam menurunkan bilangan peroksida dan asal lemak bebas pada VCO.Penelitian ini bertujuan mengetahui nilai bilangan peroksida dan asam lemak bebas pada VCO yang disuplementasi dengan sari daun kelor (Moringa oleifera L.) menggunakan metode fermentasi.Penelitian ini merupakan penelitian quasi eksperimen mengunakan rancangan acak lengkap (RAL) dengan 4 formulasi dengan variasi volume penambahan sari daun kelor F1 (0 mL); F2 (50 mL); F3 (100 mL) dan F4 (150 mL). Bilangan peroksida dan asam lemak bebas dianalisis menggunakan metode titrimetri. Analisis data menggunakan uji Kruskal Wallis dan dilanjutkan dengan uji Mann Whitney.Hasil Penelitian: penambahan sari daun kelor dapat menurunkan bilangan peroksida dan asam lemak bebas pada VCO yang dihasilkan. Bilangan peroksida terukur pada F1, F2, F3 dan F4 berturut-turut adalah 5,76; 3,33; 2,42 dan 1,82 meq/kg, sedangkan kadar asam lemak bebas terukur berturut-turut sebesar 0,4; 0,36; 0,31 dan 0,2 %.Kesimpulan: Semakin besar volume sari daun kelor yang ditambahkan maka nilai bilangan peroksida dan kadar asam lemak bebas pada VCO semakin rendah.
PENINGKATAN KELARUTAN SIMVASTATIN MELALUI PENAMBAHAN BAHAN PENGOMPLEKS SULFANILAMID Arlan Imran; Prisca Safriani Wicita; Zulfiayu Sapiun
JURNAL KATALISATOR Vol. 8 No. 1 (2023): Jurnal Katalisator Volume 8 No. 1, April 2023
Publisher : LLDIKTI X Sumbar, Riau, Jambi, Kepri

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (212.034 KB) | DOI: 10.62769/katalisator.v8i1.2205

Abstract

Simvastatin is a drug used to lower cholesterol levels in the blood. The mechanism of action of simvastatin is by inhibiting the enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, which competitively inhibits the cholesterol biosynthesis process in the body. Simvastatin is included in the class II BCS (Biopharmaceutics Classification System) drug, which has low water solubility and high permeability. The low solubility of simvastatin in water will affect its bioavailability in the body, which result in a therapeutic effect that is not achieved. Drug complexation is a method used to determine the solubility of a compound by adding a complexing agent. Complexing materials that are often used in other research are materials that do not have therapeutic activity such as cyclodextrin, but ini this study used complexing material from anti-microbial drug class by utilizing the reaction of glucoronide formation in the glucoronic acid structure of sulfanilamide. This research is a quantitative research with a laboratory experimental trial method which aims to see the effect of adding sulfanilamide complexing agents at various concentrations (25 ppm, 50 ppm, 75 ppm, and 100 ppm) on the solubility level of simvastatin using the acid-base titration method. The dissolved simvastatin concentration values ​​for F1, F2, F3, F4, and F5 were 0.261 ± 0.087, respectively; 0.348 ± 0.151; 0.416 ± 0.195; 0.444 ± 0.163; 0.539 ± 0.118. The results obtained showed that the higher concentration of the sulfanilamide complexing agent added, the greater solubility of simvastatin.
Analisis Pengelolaan Obat di Instalasi Farmasi Dinas Kesehatan Kabupaten/Kota Se-Provinsi Gorontalo Periode Tahun 2018 dan 2019 Husain, Fadli; Kamba, Vyani; Zulfiayu, Zulfiayu; Imran, Arlan K
Journal of Experimental and Clinical Pharmacy (JECP) Vol 2, No 1 (2022): February 2022
Publisher : Poltekkes Kemenkes Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52365/jecp.v2i1.352

Abstract

Instalasi farmasi sering menghadapi permasalahan pada tahap seleksi, perencanaan dan pengadaan. Pengelolaan obat yang buruk menyebabkan tingkat ketersediaan obat menjadi berkurang, terjadi kekosongan obat, banyaknya obat yang menumpuk karena tidak sesuainya perencanaan obat, serta banyaknya obat yang kadaluwarsa/rusak akibat sistem distribusi yang kurang baik sehingga dapat berdampak kepada inefisiensi penggunaan anggaran/biaya obat di tingkat Kabupaten/Kota. Penelitian ini menggunakan rancangan deskriptif dengan pengambilan data secara retrospektif dan concurent. Penelitian ini dilaksanakan di Instalasi Farmasi Kab. Kota se-Provinsi Gorontalo. Alat ukur penelitian ini adalah daftar pertanyaan berdasarkan indikator standar yang telah ditetapkan sesuai pedoman yang digunakan untuk monitoring dan evaluasi pengelolaan obat kabupaten/kota, serta melakukan wawancara langsung kepada penanggung jawab Instalasi Farmasi setempat. Hasil penelitian didapatkan bahwa; alokasi dana pengadaan obat tahun 2018 > 2 Miliar rupiah dan tahun 2019 1,7 Miliar - 4,3 Miliar rupiah. Terdapat 50% Kabupaten/kota yang sudah memiliki Tim Perencanaan Obat Terpadu (TPOT) di lingkungan Dinas Kesehatan. Biaya obat perkapita bila menggunakan standar WHO 1 US$ perkapita maka 80% Kabupaten/Kota sudah sesuai bahkan melampaui, hanya 1 kabupaten yang dibawah standar WHO. Terdapat 83% Kabupaten/kota yang kesesuaian item obat dengan DOEN diatas 80% dan seluruh  Kabupaten Kota mempunyai kesesuaian FORNAS lebih dari 80%.Pharmaceutical installations often face problems at the selection, planning, and procurement stages. Poor drug management causes decreasing the level of drug availability, drug vacancies, overstock of drugsdue to inappropriate drug planning, and expired/damaged drugs due to a poor distribution system can have an impact on inefficiency in the use of drug budgets/costs at the Regency/City. This study used a descriptive design with retrospective and concurrent. This research was conducted at the Pharmacy Installation at the Regency/City in Gorontalo Province. The measuring instrument for this research is a list of questions based on standard indicators that have been set according to the guidelines used for monitoring and evaluating regency/citydrug management and conducting direct interviews with the PIC of the local Pharmacy Installation. The results of the study found that; the allocation of funds for drug procurement in 2018 was more than 2 billion rupiah and in 2019 was 1.7 billion - 4.3 billion rupiah. There are 50% of regencies/cities already have an Integrated Drug Planning Team (TPOT) within the Health Office. Drug costs per capita when using the WHO standard of US$ 1 per capita, 80% of districts/cities comply and even exceed, only 1 district is below the WHO standard. There are 83% of regencies/cities whose conformity of drug items with DOEN is above 80% and all regencies/cities have FORNAS conformity of more than 80%.
Peningkatan Kesadaran Tentang Side Effect Of Herbal Medicine Pada Masyarakat Di Kelurahan Hutuo Kabupaten Gorontalo Tuloli, Teti Sutriyati; Thomas, Nurain; Latif, Multiani S; Zulfiayu, Zulfiayu
Jurnal Pengabdian Masyarakat Farmasi : Pharmacare Society Vol 3, No 3 (2024)
Publisher : State University of Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37905/phar.soc.v3i3.27587

Abstract

Obat tradisional yang digunakan untuk meningkatkan imunitas atau daya tahan tubuh telah berkembang dengan berbagai variasi bentuk. Bentuk obat tradisional yang ada saat ini seperti bubuk, cairan,tablet, rajangan, obat gosok dan lainnya. Menurut hasil Riskesdas 2018 proporsi pemanfaatan pengobatan tradisional di Provinsi Gorontalo sebanyak 25,8% dalam bentuk ramuan jadi, dan 42,6% ramuan buatan sendiri, Kota Gorontalo menempati peringkat ke-4 terbanyak proporsi pemanfaatan obat tradsional dengan jumlah 24,16% ramuan jadi dan 40,83% ramuan buatan sendiri. Tujuan pelaksaanan Kegiatan Join Kemitraan ini adalah Meningkatkan kesadaran masyarakat Kelurahan Hutuo, Kabupaten Gorontalo tentang efek samping obat herbal serta memotivasi masyarakat untuk lebih waspada terhadap kejadian efek samping obat herbal. Kegiatan Join Kemitraan ini dilaksanakan melalui edukasi dan sosialisasi tentang pentingnya kesadaran Masyarakat akan kejadian efek samping obat .Program Kegiatan Join Kemitraan ini dilaksanakan mulai 2 September 2024 di Desa Hutuo, Kabupaten Gorontalo dengan jumlah peserta sebanyak 30 orang Masyarakat Desa Hutuo, Kabupaten Gorontalo. Adanya sinergitas yang baik antara Aparat desa, Kader Kesehatan, Masyarakat desa dan Tim dari Dosen dan Mahasiswa maka seluruh program pengabdian join kemitraan dapat terlaksana dengan baik dan sukses guna mewujudkan Kelurahan Hutuo bebas dari efek samping obat herbal.
Probabilitas Side Effects of Herbal Medicine di Kota Gorontalo Tuloli, Teti Sutriyati; Madania, Madania; Tungadi, Robert; Sapiun, Zulfiayu
Indonesian Journal of Pharmaceutical Education Vol 4, No 3 (2024): September-Desember 2024
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v4i3.27733

Abstract

The probability of side effects of herbal medicine refers to the negative or undesirable impacts that may arise after consuming products made from natural ingredients or plants. This can include various physical reactions, health issues, or unwanted disorders, ranging from mild to severe. It's important to remember that while herbal medicines are often seen as a more natural option, they still have the potential to cause side effects, just like synthetic drugs. The aim of this research is to identify the probability of side effects of herbal medicine. This research is an observational study with a quantitative descriptive research design using a cross-sectional approach. This research method uses the Naranjo Algorithm. The results indicate that based on the assessment of the causality of ADRs, the outcomes obtained are possible (82.47%), probable (10.31%), and doubtful (7.22%).
The effectiveness of butterfly pea hydrogel film (Clitoria Ternatea) with chitosan and poly-vinyl-alcohol based as diabetic wound healing Wicita, Prisca Safriani; Daud, Rizka Puji Astuti; Sapiun, Zulfiayu; Yahya, Cindy; Wantaa, Nurunnisa; Mohamad, Fihrina; Imran, Arlan K.; Hartati, Hartati; Husain, Fadli
JURNAL ILMU KEFARMASIAN INDONESIA Vol 22 No 2 (2024): JIFI
Publisher : Faculty of Pharmacy, Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/jifi.v22i2.1483

Abstract

Butterfly pea possesses antioxidant activities with IC50 470 μg/ml of wound healing acceleration quality. Hydrogel for diabetic wound healing due to its physical characteristic that binds water, aside from its qualities that wets the surface and bio-compatibility in the body. This study aimed to identify effectivity test of hydrogel film preparation with butterfly pea (clitoria ternatea l.) Water extract for diabetic wound healing, employing true experimental method which involves 12 rats divided into 4 groups. The control group was treated without the Hydrogel (HET) or HET0 on hyperglycemic rats, HET1 (2%), HET2 (5%), and HET3 (7.5%). The findings revealed wounds treated with HET0 was healed in 9 days with 11.13 mm of diameter (100%), HET1 was healed in 6 days with 15.22 mm of diameter (100%), HET2 that was healed in 4 days with 11.29 mm of diameter (100%), and HET3 that was healed in 8 days with 9.05 mm of diameter (100%). It was concluded that the effectivity test revealed that the best formula is HET2 (5%) healed in 4 days with 11.29 mm of diameter in 100%.
Pemberdayaan Kelompok Keluarga dalam memenuhi Protein Hewani (Ikan Lele) untuk Pencegahan dan Penanganan Balita Stunting di Huntu Utara Pangalo, Paulus; Ischak, Wenny Ino; Aswad, Ahmad; Zulfiayu, Zulfiayu; Papuke, Sri Susanti
JOURNAL OF NONCOMMUNICABLE DISEASES Vol 5, No 2 (2025): November 2025
Publisher : Poltekkes Kemenkes Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52365/jond.v5i2.1429

Abstract

Prevalensi stunting di Provinsi Gorontalo tahun 2021 sebesar 29% dan tahun 2022 terjadi penurunan menjadi 23,8%. Di Kabupaten Bone Bolango prevalensi stunting tahun 2021 sebesar 25,1% dan pada tahun 2022 terjadi penurunan menjadi 22,3%. Hasil penimbangan pada bulan Maret 2023 menunjukkan bahwa dari 65 balita, sebanyak 8 balita (12%) tergolong sangat pendek berdasarkan indikator tinggi badan menurut umur (TB/U), dan 10 balita (15%) mengalami gizi kurang berdasarkan indikator berat badan menurut umur (BB/U). Temuan ini menunjukkan bahwa proporsi balita stunting di Desa Huntu Utara masih berada di bawah angka rata-rata Kabupaten Bone Bolango. Stunting di desa tersebut terutama disebabkan oleh rendahnya asupan nutrisi, khususnya protein hewani, yang berkaitan dengan keterbatasan pendapatan keluarga. Program pengabdian kepada masyarakat ini bertujuan untuk menurunkan prevalensi stunting, meningkatkan pengetahuan keluarga mengenai pencegahan dan penanganan stunting, serta memperkuat pemahaman keluarga tentang peran mereka dalam bidang kesehatan, dan tersedianya 1 unit kolam budidaya ikan lele dengan metode bioflok. Hasil kegiatan menunjukkan adanya peningkatan pengetahuan sasaran mengenai pencegahan dan penanganan stunting, dari < 80% sebelum intervensi menjadi > 85% setelah intervensi. Selain itu, terjadi pula peningkatan pengetahuan sasaran tentang peran keluarga di bidang kesehatan, dari < 75% sebelum intervensi menjadi > 85% setelah intervensi. Terjadi penurunan kasus balita stunting dari 8 balita menjadi 4. Tersedia kolam sudah terisi ikan lele sebanyak 1.300 ekor dan dapat dipanen bulan Januari 2025.The prevalence of stunting in Gorontalo Province in 2021 was 29%, and it declined to 23.8% in 2022. In Bone Bolango Regency, the prevalence of stunting was 25.1% in 2021 and decreased to 22.3% in 2022. Anthropometric assessments conducted in March 2023 showed that among 65 children under five, 8 children (12%) were classified as severely stunted based on the height-for-age (H/A) indicator, and 10 children (15%) were identified as underweight according to the weight-for-age (W/A) indicator. These findings indicate that the proportion of stunted children in Huntu Utara Village remains below the average prevalence in Bone Bolango Regency. Stunting in this village is primarily attributed to inadequate nutritional intake, particularly animal protein, which is associated with limited household income. This community engagement program aimed to reduce stunting prevalence, improve family knowledge regarding stunting prevention and management, strengthen family understanding of their roles in maintaining health, and establish one unit of a biofloc-based catfish aquaculture pond. The results demonstrated an increase in participants’ knowledge of stunting prevention and management, from <80% prior to the intervention to >85% after the intervention. In addition, knowledge related to family roles in health increased from <75% before the intervention to >85% afterward. A reduction in stunting cases was also observed, from eight children to four. One aquaculture pond stocked with 1,300 catfish was successfully established and is expected to be ready for harvest in January 2025.