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A Rare Case of Dural Tail Sign in the Patient with Glioblastoma Multiforme: A Case Report Risdiansyah Risdiansyah; Kusuma Eko Purwantari; Viskasari P Kalanjati; Rahadian I Susilo
AKSONA Vol. 3 No. 2 (2023): JULY 2023
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/aksona.v3i2.46639

Abstract

Highlight: A dural tail sign was found in T1W1-MR-images with contrast of a patient with glioblastoma multiforme. Glioblastoma multiforme as a grade IV malignancy of the astrocytes' glioma, the dura mater can be infiltrated and shown as DTS, although rarely reported.   ABSTRACT Introduction: The dural tail sign (DTS), which is rarely seen in patients with glioblastoma multiforme (GBM), is reported here. This sign is generally found as a manifestation of meningioma due to the reactive changes of the tumor’s invasion. Case: A 61-year-old Javanese man presented with a gradually worsening headache two months prior to hospital admission. He also suffered from paralysis of his right extremities. His complete blood tests and clinical chemistry were within normal limits. A head CT scan showed a large mass near the convexity of the brain in the left parietal lobe, along with edema and a shift of the midline structures to the right. This was confirmed on the T1W1 MR images with contrast, where DTS was clearly shown. Following surgical resection and tumor excision, histopathology analysis revealed GBM with malignant cell infiltration to the dura in the vicinity of the neoplasm. Conclusion: Here we showed a DTS in GBM as a malignant infiltration marker into the dura    
Animal Models for Studying Post-Stroke Neuroplasticity Risdiansyah, Risdiansyah; Ghiffari, Ahmad; Oktariza, Rury Tiara; Rusdi, Fadhillah Putri
Jurnal Impresi Indonesia Vol. 4 No. 5 (2025): Indonesian Impression Journal (JII)
Publisher : Riviera Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58344/jii.v4i5.6647

Abstract

Ischemic stroke remains one of the leading causes of long-term disability worldwide, with recovery dependent on the brain's neuroplastic potential. This review aims to evaluate the role of animal models in elucidating the mechanisms of neuroplasticity following stroke and their relevance to clinical application. Using qualitative literature analysis, the study synthesizes findings from various animal models including rodents, non-human primates, zebrafish, and Drosophila. Rodent models, particularly the middle cerebral artery occlusion (MCAO), have been instrumental in identifying key processes such as BDNF-driven synaptic remodeling, VEGF-induced angiogenesis, and glial involvement in tissue repair. Additionally, systemic modulators like the gut-brain axis, immune responses, and extracellular vesicles are increasingly recognized for their influence on recovery. Despite these insights, most studies disproportionately utilize young, healthy male animals, limiting their relevance to diverse patient populations with comorbidities and aging factors. The findings suggest a need for integrative, multimodal research that incorporates molecular techniques, imaging, and behavioral assays, along with cross-species validation, to improve translational outcomes. This review underscores the necessity of leveraging a broader spectrum of animal models and advanced methodologies to develop effective, personalized therapies for post-stroke rehabilitation.
Collaborative Malaria Surveillance Ending Outbreak In Merangin: Early Response By Academia And Muhammadiyah Community Ghiffari, Ahmad; Risdiansyah, Risdiansyah; Qamariah, Nurul; Faradila, Faradila; Shalshabilla, Alysha Titania; Mukhtarudin, Kuntafie Al Haq; Safitri, Rizka Nabila; Prameswarie, Thia; Ramayanti, Indri; Asmalia, Resy
Jurnal Kreativitas Pengabdian Kepada Masyarakat (PKM) Vol 8, No 8 (2025): Volume 8 No 8 (2025)
Publisher : Universitas Malahayati Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jkpm.v8i8.21282

Abstract

ABSTRACT The Mass Blood Survey (MBS) conducted in August 2023 in Sungai Tebal Village, Jambi Province, in response to a malaria outbreak declared by the Regent of Merangin. The outbreak began with 52 confirmed malaria cases (50 Plasmodium vivax and 2 Plasmodium falciparum), indicating a substantial rise compared to previous years. The District Health Office, an academic institution, and community health partnered to carry out the MBS, which was launched six months after the index case. Prior to implementation, the team coordinated with local health authorities and community organization thus prepared for both rapid diagnostic testing (RDT) and public health education. A total of 33 individuals were tested, and all RDT results were negative, indicating no further local transmission. The findings underscored the importance of early detection, collaborative efforts, and sustained preventive strategies in malaria-endemic regions to avert future outbreaks. Keywords: Active Surveillance, Malaria Elimination, Outbreak Response, Rural Health, Integrated Control
Penguatan Peran Dokter Dalam Upaya Promotif dan Preventif dengan Pendekatan Kedokteran Keluarga Melalui Edukasi Akademik dan Praktik Langsung di Masyarakat [Strengthening the Role of Doctors in Promotive and Preventive Efforts Through Family Medicine Approach via Academic Education and Direct Practice in the Community] Badri, Putri Rizki Amalia; Mayasari, Ni Made Elva; Umar, Erfiana; Aprina, Fenty; Trisnawarman, Trisnawarman; Artanto, Ardi; Risdiansyah, Risdiansyah; Winarto, Winarto; faradilla, faradilla
Indonesia Berdaya Vol 6, No 4 (2025)
Publisher : UKInstitute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47679/ib.20251319

Abstract

Abstract. Communicable diseases and Non-Communicable Diseases (NCDs) such as hypertension, Diabetes Mellitus (DM), and Tuberculosis require a family medicine approach. Hypertension, often referred to as the silent killer, remains a major public health challenge due to its high prevalence among adults. More than half (59%) of adults aged 30 and above living with diabetes did not take medication for their condition in 2022. The lowest coverage of diabetes treatment is found in low- and middle-income countries. Ending the Tuberculosis (TB) epidemic by 2030 is one of the health targets in the United Nations Sustainable Development Goals (SDGs). This community service activity was conducted at the Ahmad Dahlan Building, Faculty of Medicine, Universitas Muhammadiyah Palembang. Through this activity, it is expected that prolanis participants gain knowledge about DM, TB, and hypertension, as well as their preventive measures. The activity consisted of direct counseling regarding DM, TB, and hypertension. The participants’ knowledge level was measured using pre-test and post-test questionnaires related to the counseling material, involving 36 participants. The results showed an increase in knowledge from 54.8% to 65.2%. Participants were enthusiastic and actively engaged during the discussion sessions. All participants attended the counseling and demonstration sessions until completion. This community service activity can improve public knowledge and awareness regarding DM, hypertension, and TB. Abstrak. Penyakit menular dan Penyakit Tidak Menular (PTM) memerlukan pendekatan kedokteran keluarga seperti hipertensi, Diabetes Mellitus (DM) dan Tuberkulosis. Hipertensi, yang sering disebut sebagai silent killer masih menjadi tantangan kesehatan masyarakat utama karena prevalensinya yang tinggi di kalangan orang dewasa. Lebih dari separuh (59%) orang dewasa berusia 30 tahun ke atas yang hidup dengan diabetes tidak mengonsumsi obat untuk diabetes mereka pada tahun 2022. Cakupan pengobatan diabetes terendah berada di negara-negara berpenghasilan rendah dan menengah. Mengakhiri epidemi Tuberkulosis (TB) pada tahun 2030 merupakan salah satu target kesehatan dalam Tujuan Pembangunan Berkelanjutan (SDGs) Perserikatan Bangsa-Bangsa Kegiatan pengabdian masyarakat ini berlokasi di Gedung Ahmad Dahlan FK UM Palembang. Melalui kegiatan ini diharapkan para peserta prolanis mendapatkan pengetahuan mengenai penyakit DM, TB dan Hipertensi serta upaya pencegahannya.  Kegiatan ini berupa penyuluhan secara langsung mengenai penyakit DM, TB dan Hipertensi. Pengukuran tingkat pengetahuan peserta dilakukan melalui pre-test dan post-test menggunakan kuisioner yang terkait dengan materi penyuluhan kepada 36 orang peserta. Hasil pengukuran didapatkan peningkatan pengetahuan peserta dari 54,8 % menjadi 65,2%. Peserta antusias mengikuti kegiatan serta aktif pada sesi diskusi. Seluruh peserta mengikuti proses penyuluhan dan demonstrasi hingga selesai. Kegiatan pengabdian masyarakat dapat meningkatkan pengetahuan dan kesadaran masyarakat mengenai penyakit DM, Hipertensi dan TB.