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All Journal Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Majalah Farmaseutik Jurnal Farmasi Medica (Pharmacy Medical Journal) PMJ Jurnal Riset Kefarmasian Indonesia Jurnal Mandala Pengabdian Masyarakat Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Jurnal Komunitas Farmasi Nasional Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan Jurnal Pengabdian Ikifa Jurnal Farmasi Ikifa
Prayoga, Tria
Sekolah Tinggi Ilmu Kesehatan IKIFA
Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Mathematics Medicine & Pharmacology Nursing Public Health Social Sciences

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ANALISIS PREDIKSI EFEK ANTIINFLAMASI PADA PIPER PORPHYROPHYLLUM SECARA IN SILICO Prayoga, Tria; Rahmat, Deni; Sandhiutami, Ni Made Dwi; Desmiaty, Yesi
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 10 No 1 (2025): Jurnal Ilmiah Ibnu Sina
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jiis.v9i2.2352

Abstract

This study aims to predict the anti-inflammatory effects of compounds in Piper porphyrophyllum using in silico methods. The compounds were analyzed using AutoDock software to evaluate their binding potential with the target protein and Lipinski's rule of five to assess their drug-likeness based on pharmacokinetic properties. Qualitative results show that compounds such as 4'-hydroxy-3',5,7-trimethoxyflavone, 4',5-dihydroxy-3',7-dimethoxyflavone, and 5-hydroxy-3',4',7-trimethoxyflavone form significant interactions with key residues on the target protein. Quantitatively, these compounds exhibit more negative binding free energy compared to the natural ligand (-7.34 kcal/mol), with values of -8.35 kcal/mol, -8.13 kcal/mol, and -8.20 kcal/mol, respectively, indicating stronger binding affinity. Evaluation using Lipinski's rule shows that these compounds meet the criteria as potential drug candidates. In conclusion, this in silico method can predict the potential of Piper porphyrophyllum compounds as anti-inflammatory agents, supporting further research for experimental validation.
UJI AKTIVITAS ANTIBAKTERI EKSTRAK BUNGA KECOMBRANG (Etlingera elatior (Jack) R. M.Sm.) TERHADAP BAKTERI Staphylococcus aureus Sp. Rusdiati Helmidanora; Yullia Sukawaty; Divya Miranti; Tria Prayoga; Nia Lisnawati
Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan Vol. 10 No. 1 (2024): Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v10i1.769

Abstract

Kecombrang plant contains essential oils which are bioactive, including 0.0735% in the leaves. in flowers 0.0334%, in stems 0.0029% and in rhizomes 0.0021%. Combrang flowers (Etlingera elatior (Jack)) have effective antibacterial activity. The aim of this research was to determine the level of ethanol extract of kecombrang flowers from Pampang village (100-500 masl), East Kalimantan in inhibiting Staphylococcus aureus bacteria. The object studied was the inhibitory zone of kecombrang flower extract against Staphylococcus aureus bacteria. Extract preparation was carried out using the maceration method using 96% ethanol solvent, antibacterial activity testing was carried out using the well method with extract concentrations of 10%, 20%, 40%, 60% and positive control chloramphenicol and negative control DMSO. The results of this study were that 96% ethanol extract of kecombrang flowers had antibacterial activity against Staphylococcus aureus bacteria with a maximum concentration of 60% and had a medium category inhibitory power of 5.933 mm.
Penyuluhan Pemanfaatan Daun Sirih Merah (Piper Porphyrophyllum) Sebagai Tanaman Obat Di RW 12 Kelurahan Klender, Jakarta Timur Prayoga, Tria; Rismana, Eriawan; Oktavia, Deva Maharani; Talumepa, Amanda Alycia Maria
Jurnal Mandala Pengabdian Masyarakat Vol. 6 No. 2 (2025): Jurnal Mandala Pengabdian Masyarakat
Publisher : Progran Studi Farmasi Universitas Mandala Waluya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35311/jmpm.v6i2.663

Abstract

Pemanfaatan Tanaman Obat Keluarga masih tergolong rendah di RW 12 Kelurahan Klender, Jakarta Timur, meskipun wilayah ini memiliki potensi dalam penerapan tanaman herbal sebagai upaya menjaga kesehatan keluarga. Kegiatan Pengabdian Kepada Masyarakat ini bertujuan untuk meningkatkan pengetahuan dan kesadaran masyarakat terhadap manfaat daun sirih merah sebagai tanaman obat yang dapat digunakan secara mandiri di lingkungan rumah tangga. Metode kegiatan menggunakan pendekatan edukatif-partisipatif melalui penyuluhan langsung, penyampaian materi visual, dan diskusi interaktif kepada 17 peserta. Evaluasi dilakukan melalui pre-test dan post-test untuk mengukur peningkatan pengetahuan. Hasil menunjukkan adanya peningkatan skor pengetahuan peserta dari 71,43 menjadi 85,71. Selain itu, peserta menunjukkan antusiasme tinggi dan minat untuk menanam serta memanfaatkan daun sirih merah dalam kehidupan sehari-hari. Kegiatan ini menunjukkan bahwa penyuluhan sederhana berbasis hasil penelitian dapat meningkatkan literasi kesehatan dan mendorong pemanfaatan tanaman obat lokal sebagai langkah preventif dalam menjaga kesehatan keluarga.
PEMANFAATAN MINYAK ATSIRI Litsea elliptica Blume PADA SEDIAAN SABUN CUCI TANGAN DI KELURAHAN DUREN SAWIT JAKARTA TIMUR PRA PANCA BAYU CHANDRA; IKA AGUSTINA; TRIA PRAYOGA
Jurnal Pengabdian IKIFA Vol. 3 No. 2 (2024): Jurnal Pengabdian IKIFA
Publisher : Sekolah Tinggi Ilmu Kesehatan IKIFA

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Abstract

Litsea is a plant that belongs to the Lauraceae family with 45 genera and more than 2,000 species. A total of 38 types of Litsea are known to grow in the Kalimantan region, including Litsea elliptica. Litsea elliptica is reported to have a dominant distribution in East Kalimantan. The aim of the Community Service (PkM) activities in Duren Sawit Subdistrict is to educate the public about the use of Litsea elliptica Blume Essential Oil in hand washing soap preparations. The PkM activity was attended by 45 residents from various areas in Duren Sawit Village. The results of the PkM activities showed an increase in respondents' knowledge about the use of Litsea elliptica Blume Essential Oil in hand washing soap preparations.
IDENTIFIKASI KANDUNGAN FORMALIN PADA KUE YANG BEREDAR DI PASAR TRADISIONAL PERUMNAS KLENDER JAKARTA TIMUR Tria Prayoga; Pricillya Maria Loimalitna; Ivan Santoso; Asfiati Asysyifaa
Jurnal Farmasi IKIFA Vol. 2 No. 1 (2023): JURNAL FARMASI IKIFA VOL.2 NO.1 TAHUN 2023
Publisher : Sekolah Tinggi Ilmu Kesehatan IKIFA

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Abstract

Based on BPOM, in Indonesia there are around 20 million cases of food poisoning per year. Palembang's BPOM agency also found market snacks, kue apem cakes and a number of other foods to contain formalin. BTP (Food Additives) which are often used in food processing are preservatives such as formalin. Formalin is used because it can extend the shelf life of the food. This study aims to test the alleged presence of formaldehyde in samples of wet cakes circulating in Klender Market, East Jakarta. The method used in this study is the identification of formalin compounds by qualitative chemical analysis using Schiff's reagent. In this study, it was found that samples of apem cakes, cucur cakes and putu ayu cakes from the Perumnas Klender Traditional Market, East Jakarta, did not contain formalin compounds.
ANALISIS KANDUNGAN BIOAKTIF DAN BAHAN ORGANIK ASING PADA SIMPLISIA DAUN SIRIH MERAH (PIPER PORPHYROPHYLLUM) Tria Prayoga; Nia Lisnawati; Putri Eka Sari; Daffa Salsabiil Rohman; Hafiizhah Firyal Shafa; Tiara Fadli; Ahmad Fahmi
Jurnal Farmasi IKIFA Vol. 3 No. 3 (2024): JURNAL FARMASI IKIFA VOL.3 NO.2 OKTOBER TAHUN 2024
Publisher : Sekolah Tinggi Ilmu Kesehatan IKIFA

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Abstract

Penelitian ini bertujuan untuk mengidentifikasi senyawa bioaktif dan bahan organik asing baik dalam simplisia maupun ekstrak daun sirih merah (Piper porphyrophyllum). Simplisia dikumpulkan dari Balai Penelitian Tanaman Obat dan Aromatik (BALITTRO), Bogor, dan ditentukan di Laboratorium Generasi Biologi Indonesia, Gresik. Pemeriksaan meliputi analisis organoleptik, kadar air, dan bahan organik asing sesuai standar Materia Medica Indonesia dan Farmakope Indonesia VI. Ekstraksi dilakukan dengan menggunakan metode remaserasi dengan etanol 96%. Hasil penelitian menunjukkan bahwa bahan organik asing dalam simplisia adalah 1,43% dan kadar air adalah 0,19%, keduanya dalam batas yang dapat diterima. Hasil ekstrak adalah 26,86%, dengan hasil organoleptik menunjukkan warna hijau tua, khas bau herbal, dan rasa pedas-pahit. Skrining fitokimia mengungkapkan keberadaan alkaloid, flavonoid, dan tanin dalam ekstrak. Kesimpulannya, simplisia dan ekstrak daun sirih merah memiliki kualitas yang baik dan mengandung senyawa aktif yang mendukung potensi farmakologisnya sebagai bahan obat herbal
Co-Authors Ahmad Fahmi Asfiati Asysyifaa CHANDRA, PRA Daffa Salsabiil Rohman Deshinta Imelia Divya Miranti Efrilia, Mega Efrilia, Mega Eriawan Rismana Fauziah, Sarah Fidri Setia Ningsih Hafiizhah Firyal Shafa Ika Agustina Ivan Rahmat Santoso Lisnawati, Nia Mega Efrilia Mekasari, Nur Mudinillah, Adam Ni Made Dwi Sandhiutami Nia Lisnawati Nia Lisnawati Nur Mekasari NURUL HIDAYAH Oktavia, Deva Maharani Panca Bayu Chandra, Pra PRA PANCA BAYU CHANDRA Pricillya Maria Loimalitna Putri Eka Sari Putri Eka Sari Raden Mohamad Herdian Bhakti Rahayu, Wiwit Setya Rahmat Widiyanto RAHMAT, DENI Robby, Rohima Rusdiati Helmidanora Talumepa, Amanda Alycia Maria Tiara Fadli Widiyanto, Rahmat Yesi Desmiaty, Yesi Yullia Sukawaty