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All Journal Jurnal Ilmu Kefarmasian Indonesia JURNAL FARMASIMED (JFM) Jurnal Kesehatan Tambusai Archives Pharmacia Journal of Experimental and Clinical Pharmacy (JECP) Duta Pharma Journal Proceeding of International Conference Health, Science And Technology (ICOHETECH) Prosiding Seminar Informasi Kesehatan Nasional
Rahmatillah, Annie
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Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Education Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health

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Journal : JURNAL FARMASIMED (JFM)

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Synergistic Impact of The Combination of Moringa Leaves and Butterfly Pea Flowers Infusion on Cognitive Enhancement Annie Rahmatillah; Anna Fitriawati; Anisa Fadilah Kumala Putri
Jurnal FARMASIMED (JFM) Vol 8 No 1 (2025): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/n9214f64

Abstract

Oxidative stress can induce memory loss, which may be mitigated by antioxidants. Moringa leaves (Moringa oleifera) and butterfly pea flowers (Clitoria ternatea) possess flavonoid chemicals that function as natural antioxidants. This study seeks to evaluate the impact of combined Moringa leaf and butterfly pea flower infusions on enhancing the memory of mice and to identify the optimal dosage. The research utilized male white mice (Mus musculus), categorized into six groups: a normal group, a negative control (aquadest), a positive control (Ginkgo biloba), and three treatment groups receiving various infusion doses. The procedure had three phases: acclimatization (T0), intraperitoneal administration of hyoscine butylbromide (T1), and therapy (T2). The manufacture of INDUK BUNTEL (an infusion of moringa leaves and butterfly pea flowers) was conducted using an infusion extraction method. Testing on test subjects was conducted utilizing the Radial Arm Maze methodology. The findings indicated that the infusion combination at dose III (100 mg/KgBW: 100 mg/KgBW) was the most efficacious in enhancing the memory of mice. The mean mistake rate in mice was 16.44%, representing the lowest score among the treatment groups. The one-way ANOVA test indicated no significant difference across treatment groups with three distinct dose combinations (p > 0.05).
Co-Authors 'Arifah, Zainul Agustiningrum, Nurul Anisa Fadilah Kumala Putri Anna Fitriawati Apriliya, Intan Bagas Ardiyantoro Fatika Puteri Rosyi Prabowo Ika Trisharyanti Dian Kusumowati Insani, Fitri Nur Irhamadi Malik Larasati, Karina Dwi Luthfiyanti, Niken Mahendra, Andika Dwi Marwiyati, Vivin Pratama, Kharisma Jayak Puspita Sari, Mawar Dela Putri, Anisa Fadilah Kumala Qurniawati, Eka Rahmat Hidayat Riza Monasyifa Rohmana, Vivin Marwiyati Rosi Hayyu Anjani Saputri, Dina Tika Sari, Sindy Avita UTARI SITA ARDANI Wardani, Tatiana Siska YULIANA RIZQI DWI RATNA Yusuf, Dea Sagitarina ZAKIAH FATHIANA