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All Journal Journal of Dentistry Indonesia ODONTO Dental Journal ABDI MOESTOPO: Jurnal Pengabdian pada Masyarakat Jurnal Kedokteran Gigi Terpadu JURNAL ABDI MASYARAKAT INDONESIA (JAMIN) Jurnal Abdimas Kesehatan Terpadu Odonto dental journal Jurnal Abdimas Kesehatan SDJ
Hartanto, Firstine Kelsi
Universitas Trisakti
Humanities Biochemistry, Genetics & Molecular Biology Dentistry Earth & Planetary Sciences Education Energy Engineering Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Other

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Pigmented Oral Lichen Planus: A Case Report Firstine Kelsi Hartanto; Thomas George Kallarakal
Scientific Dental Journal VOLUME 1, ISSUE 1, SEPTEMBER 2017
Publisher : Faculty of Dentistry, Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25105/sdj.v1i1.1923

Abstract

Background: Lichen planus is a chronic muccocutaneous inflammatory disorder. Oral lichen planus (OLP) has certain specific characteristics in its clinical presentation, but can also be presented in forms resembling other diseases. This may introduce difficulty in the diagnostic process. It has been reported that OLP affects between 0.1 to 4% individuals, predominantly women and people over 40 years old. Case Report: A 46-year-old woman complained of a non-healing ulcer present for 1.5 months. Intraorally, multiple white striae with prominent central areas of brownish hyperpigmentation were apparent on the right and left buccal mucosa, right and left buccal sulcus, and lateral and dorsum of the tongue. A biopsy was completed and the histopathology features confirmed the diagnosis of OLP. For the initial treatment, a topical corticosteroid was prescribed, followed by steroid mouthwash. Response to this treatment was positive. OLP has been frequently reported to affect women over the age of 40, with psychological stress as a primary predisposing factor. The clinical presentation is characteristic of Wickham’s striae with erosive areas. However, a biopsy and histopathological examination is mandatory to confirm the diagnosis. The clinical feature of pigmented OLP has been reported and confirmed by microscopic finding of band-like lymphocytic appearance which is the pathognomonic features of OLP, along with basal cell liquefaction degeneration, and melanin in continence at the lamina propria. Conclusion: Pigmented OLP is a variant of erosive OLP. Anamnesis, clinical presentation, and histopathological examination confirm diagnosis.
A Case Report of Angiosarcoma of Maxillary Gingiva: Histopathology Aspects Firstine Kelsi Hartanto; Shin Hin Lau
Scientific Dental Journal VOLUME 2, ISSUE 2, MAY 2018
Publisher : Faculty of Dentistry, Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25105/sdj.v2i2.2681

Abstract

Background: Angiosarcoma is a rare malignant tumor, which most often occurs in the skin and soft tissue. Its occurrence in the head and neck region, and the intraoral region in particular, is uncommon. The aim of this case report is to highlight the importance of histopathological examination and to underscore the characteristic features of angiosarcoma. Case report: A 52-year-old female presented with a growth in the right maxillary portion of the interdental region of her molar teeth. The growth had been present for approximately one month. A computerized tomography (CT) scan showed metastatic tumors in the lungs, liver, bone, and soft tissue of maxillary gingiva. Intraoral examination found a soft and mobile pedunculated ovoid mass at the right palatal gingiva; the mass was reddish-blue in color. An incisional biopsy was performed to confirm the diagnosis and plan for further treatment. Histopathologic examination revealed malignant endothelial cells in a vasoformative growth pattern, with numerous vascular channels lined with neoplastic endothelium-forming intraluminal buds, projections, and papillae. These projections were interspersed with the tumor cells. Immunohistochemistry analysis showed these endothelial cells demonstrated strong positive immunoreactivity with CD31, factor VIII, and FLi-1. A diagnosis of angiosarcoma was made. Discussion: Because intraoral angiosarcoma is rare and its clinical presentation can resemble other vascular lesions, it can be a challenging diagnosis for clinicians and pathologists. In the present case, the diagnosis of intraoral angiosarcoma was made based on clinical and histopathology findings. The microscopic features of malignant endothelial cells and the presence of intraluminal projections, supported by positive immunoreactivity with CD31, factor VIII, and FLi-1, confirmed the diagnosis. Conclusion: Angiosarcoma poses a diagnostic challenge to dental practitioners and oral pathologists due to the rarity of occurrence in the oral cavity. Histopathological examination is critical for an accurate diagnosis.
Co-Authors Albert Alexandra Vanessa Gunawan Andri Sutanto Andrijanto Andrijanto, Andrijanto Ariyani, Annisaa Putri Aryadi Beby Sophiana, Beby Sophiana Caroline Septiani Dewi Agustini Dewi Kusuma, Riesta Paluvi Dewi Priandini Echita Mulia Saputri Elisabeth Sudarmi Elizabeth Fitriana Sari Evita Dewi Fortuna Gunawan, Dika Andiana Sari Hartanto, Firstine Hartanto Henry Tedja, Christian Heriandi, Alyah Herwanto, Tiffany IG Sanditya Ardiana Ilona Krista J Indrayadi Gunardi Indrayadi Gunardi Indrayadi Gunardi, Indrayadi Irene Tania Bijaya Jacinda Jesslyn Komariah Komariah Komariah Krysta Yosvara Kurniawan, Angelita Victoria Luki Astuti M. Orliando Roeslan Mikha Sundjojo Nadiah, Najla Natahnie, Fransiskus Arnold Naufal, Nafia Syifa Nikita Theodorus Niko Falatehan Rahma Landy Rahmi Amtha Rahmi Amtha Rahmi Amtha Rahmi Amtha Septifionna, Haura Agni Shin Hin Lau Soesanto, Sheila Stephanie Ayu Budi K Sudarmi, Elisabeth Tedja, Christian Henry Thomas George Kallarakal Trijani Suwandi Winarto, Jessica Valerie Wiwiek Poedjiastoeti, Wiwiek Yohana Yusra Yonathan, Dick